LES LABORATOIRES SERVIER Patent applications |
Patent application number | Title | Published |
20140296512 | PROCESS FOR THE SYNTHESIS OF 7,8-DIMETHOXY-1,3-DIHYDRO-2H-3-BENZAZEPIN-2-ONE COMPOUNDS, AND APPLICATION IN THE SYNTHESIS OF IVABRADINE - Process for the synthesis of the compound of formula (I): | 10-02-2014 |
20140249215 | NEW SALT OF ABEXINOSTAT, ASSOCIATED CRYSTALLINE FORM, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM - Abexinostat tosylate of formula (II): | 09-04-2014 |
20140242644 | PROCESS FOR THE ENZYMATIC SYNTHESIS OF (7S)-3,4-DIMETHOXYBICYCLO[4.2.0]OCTA-1,3,5-TRIENE-7-CARBOXYLIC ACID AND APPLICATION IN THE SYNTHESIS OF IVABRADINE AND SALTS THEREOF - Process for the enzymatic synthesis of the compound of formula (I): | 08-28-2014 |
20140241989 | NOVEL IMAGING AGENTS, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME - Compounds of formula (I) in which: >R is a linear or branched (C | 08-28-2014 |
20140221449 | DIVIDABLE GALENICAL FORM ALLOWING MODIFIED RELEASE OF THE ACTIVE INGREDIENT - Dividable galenical form for the modified release of active ingredient, wherein the non-subdivided galenical form and a portion of said form obtained by subdivision have identical dissolution profiles. | 08-07-2014 |
20140163220 | PROCESS FOR THE SYNTHESIS OF 3-(2-BROMO-4,5-DIMETHOXYPHENYL)PROPANENITRILE, AND APPLICATION IN THE SYNTHESIS OF IVABRADINE AND ADDITION SALTS THEREOF WITH A PHARMACEUTICALLY ACCEPTABLE ACID - Process for the synthesis of the compound of formula (I): | 06-12-2014 |
20140155453 | SYNTHESIS PROCESS, AND CRYSTALLINE FORM OF 4-{3[CIS-HEXAHYDROCYCLOPENT A[CjPYRROL-2( 1 H)-YLjPROPOXYj BENZAMI DE HYDROCHLORI DE AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT - Medicinal products containing the crystalline form I of the compound of formula (I): | 06-05-2014 |
20140128598 | PROCESS FOR THE SYNTHESIS OF (2E)-3-(3,4-DIMETHOXYPHENYL)PROP-2-ENENITRILE, AND APPLICATION IN THE SYNTHESIS OF IVABRADINE AND ADDITION SALTS THEREOF WITH A PHARMACEUTICALLY ACCEPTABLE ACID - Process for the synthesis of the compound of formula (I): | 05-08-2014 |
20140121368 | PROCESS FOR PREPARING BENZOTHIAZEPINES FROM GAMMA-AMINOALKYLBENZENES - The invention provides a process for preparing a 2,3,4,5-tetrahydro[1.4]benzothiazepine of formula: | 05-01-2014 |
20140107334 | PROCESS FOR THE SYNTHESIS OF 3-(2-BROMO-4,5-DIMETHOXYPHENYL)PROPANENITRILE, AND APPLICATION IN THE SYNTHESIS OF IVABRADINE AND ADDITION SALTS THEREOF WITH A PHARMACEUTICALLY ACCEPTABLE ACID - Process for the synthesis of the compound of formula (I): | 04-17-2014 |
20140100374 | SYNTHESIS PROCESS, AND CRYSTALLINE FORM OF 4- BENZAMIDE HYDROCHLORIDE AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT - Industrial synthesis process for the compound of formula (I): | 04-10-2014 |
20140088171 | AGENTS FOR TREATING DISORDERS INVOLVING MODULATION OF RYANODINE RECEPTORS - The present invention relates to 1,4-benzothiazepine derivatives and their use to treat conditions, disorders and diseases associated with ryanodine receptors (RyRs) that regulate calcium channel functioning in cells. The invention also discloses pharmaceutical compositions comprising the compounds and uses thereof to treat diseases and conditions associated with RyRs, in particular cardiac, musculoskeletal and central nervous system (CNS) disorders. | 03-27-2014 |
20140011883 | CRYSTAL FORM VII OF AGOMELATINE, PREPARATION METHOD AND USE THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING SAME - The present invention provides a new crystalline form VII of agomelatine, its method of preparation, application and pharmaceutical composition. This new crystalline form offers high purity, a stable crystalline structure and good reproducibility, while its method of production lends itself well to large scale production. In terms of stability and purity, it is superior to the numerous crystalline forms which have hitherto been reported. As a result, the crystalline form VII of the present invention possesses advantages in pharmaceutical preparation. | 01-09-2014 |
20130331380 | DIHYDROINDOLONE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM - Compounds of formula (I): | 12-12-2013 |
20130289308 | PROCESS FOR THE SYNTHESIS OF AGOMELATINE - Process for the industrial synthesis of the compound of formula (I) | 10-31-2013 |
20130289307 | PROCESS FOR THE SYNTHESIS OF AGOMELATINE - Process for the industrial synthesis of the compound of formula (I) | 10-31-2013 |
20130281512 | AGENTS FOR TREATING DISORDERS INVOLVING MODULATION OF RYANODINE RECEPTORS - The present invention relates to 1,4-benzothiazepine derivatives and their use to treat conditions, disorders and diseases associated with ryanodine receptors (RyRs) that regulate calcium channel functioning in cells. The invention also discloses pharmaceutical compositions comprising the compounds and uses thereof to treat diseases and conditions associated with RyRs, in particular cardiac, musculoskeletal and central nervous system (CNS) disorders. | 10-24-2013 |
20130261298 | PROCESS FOR THE SYNTHESIS OF IVABRADINE AND ADDITION SALTS THEREOF WITH A PHARMACEUTICALLY ACCEPTABLE ACID - Process for the synthesis of ivabradine of formula (I): | 10-03-2013 |
20130211070 | NEW PROCESS FOR THE RESOLUTION OF ENANTIOMERS OF (3,4 DIMETHOXY-BICYCLO[4.2.0]OCTA-1,3,5-TRIEN-7-YL)NITRILE AND APPLICATION IN THE SYNTHESIS OF IVABRADINE - Process for the optical resolution of the compound of formula (I): | 08-15-2013 |
20130210091 | PROCESS FOR THE ENZYMATIC SYNTHESIS OF (7S)-3,4-DIMETHOXYBICYCLO[4.2.0]OCTA-1,3,5-TRIENE-7-CARBOXYLIC ACID OR ESTERS THEREOF, AND APPLICATION IN THE SYNTHESIS OF IVABRADINE AND SALTS THEREOF - Process for the enzymatic synthesis of the compound of formula (I): | 08-15-2013 |
20130204032 | NEW PROCESS FOR THE RESOLUTION OF ENANTIOMERS OF (3,4 DIMETHOXY-BICYCLO[4.2.0]OCTA-1,3,5-TRIEN-7-YL)NITRILE AND APPLICATION IN THE SYNTHESIS OF IVABRADINE - Process for the optical resolution of the compound of formula (I): | 08-08-2013 |
20130202710 | PHARMACEUTICAL COMPOSITION FOR THE PROLONGED RELEASE OF TRIMETAZIDINE - Composition for the prolonged release of trimetazidine wherein the inner phase comprises trimetazidine and the outer layer comprises a retardant and an anti-agglomerant. | 08-08-2013 |
20130178635 | PROCESS FOR THE PREPARATION OF THE L-ARGININE SALT OF PERINDOPRIL - Process for the preparation of the compound of formula (I): | 07-11-2013 |
20130178464 | DELTA CRYSTALLINE FORM OF THE ARGININE SALT OF PERINDOPRIL, A PROCESS FOR ITS PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT - Delta crystalline form of the compound of formula (I): | 07-11-2013 |
20130158257 | PROCESS FOR THE SYNTHESIS OF IVABRADINE AND ADDITION SALTS THEREOF WITH A PHARMACEUTICALLY ACCEPTABLE ACID - Process for the synthesis of ivabradine of formula (I): | 06-20-2013 |
20130158256 | PROCESS FOR THE SYNTHESIS OF IVABRADINE AND ADDITION SALTS THEREOF WITH A PHARMACEUTICALLY ACCEPTABLE ACID - Process for the synthesis of ivabradine of formula (I): | 06-20-2013 |
20130150421 | COMBINATION OF 4-BENZAMIDE AND A NMDA RECEPTOR ANTAGONIST AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME - Combination between 4-{3-[cis-hexahydrocyclopenta[c]pyrrol-2(1H)-yl]propoxy}-benzamide of formula (I): | 06-13-2013 |
20130064880 | ADMINISTRATION REGIME FOR N-HYDROXY-4-BENZAMIDE - N-hydroxy-4-{2-[3-(N,N-dimethylaminomethyl)benzofuran-2-ylcarbonylamino]ethoxy}-benzamide of formula (I): | 03-14-2013 |
20130041040 | SOLID PHARMACEUTICAL COMPOSITION FOR BUCCAL ADMINISTRATION OF AGOMELATINE - The invention relates to a solid buccal pharmaceutical composition comprising agomelatine intended for systemic action. | 02-14-2013 |
20130012592 | AGOMELATINE HYDROBROMIDE HYDRATE AND PREPARATION THEREOF - The present invention relates to an agomelatine hydrobromide hydrate of formula I | 01-10-2013 |
20130005820 | AGOMELATINE HYDROCHLORIDE HYDRATE AND PREPARATION THEREOF - The present invention relates to an agomelatine hydrochloride hydrate of formula I, preparation and use thereof, and to pharmaceutical composition containing it. The agomelatine hydrohalide hydrate obtained through the present method has significant increased solubility than agomelatine, and therefore is more suitable for manufacturing pharmaceutical formulations. In addition, the product enjoys higher stability and purity. Using the present method, product of high purity can be obtained through a simple process, free of any complicated steps. | 01-03-2013 |
20120330062 | PROCESS FOR THE SYNTHESIS OF (7-METHOXY-1-NAPHTHYL) ACETONITRILE AND APPLICATION IN THE SYNTHESIS OF AGOMELATINE - Process for the industrial synthesis of the compound of formula (I) | 12-27-2012 |
20120316245 | CO-CRYSTALS OF AGOMELATINE, A PROCESS FOR THERE PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM - New co-crystal of agomelatine composed of:
| 12-13-2012 |
20120316214 | SYNTHESIS PROCESS, AND CRYSTALLINE FORM OF 4-BENZAMIDE HYDROCHLORIDE AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT - Industrial synthesis process for, and crystalline form I of, the compound of formula (I): | 12-13-2012 |
20120309838 | USE OF AGOMELATINE IN OBTAINING MEDICAMENTS INTENDED FOR THE TREATMENT OF OBSESSIVE-COMPULSIVE DISORDER (OCD) - The present invention relates to the use of agomelatine, or N-[2-(7-methoxy-1-naphthyl)ethyl]acetamide, in obtaining medicaments intended for the treatment of Obsessive-Compulsive Disorder (OCD). | 12-06-2012 |
20120283245 | AZABICYCLO[3.1.0]HEX-2-YL COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM - Compounds of formula: | 11-08-2012 |
20120283244 | ASSOCIATION BETWEEN 4-BENZAMIDE AND AN ACETYLCHOLINESTERASE INHIBITOR, AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT - Association between 4-{3-[cis-hexahydrocyclopenta[c]pyrrol-2(1H)-yl]propoxy}benzamide of formula (I): | 11-08-2012 |
20120245363 | PROCESS FOR THE SYNTHESIS OF AGOMELATINE - Process for the industrial synthesis of the compound of formula (I) | 09-27-2012 |
20120232065 | DIHYDRO-OXAZOLOBENZODIAZEPINONE COMPOUNDS, A PROCESS FOR THERE PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM - Compounds of formula (I): | 09-13-2012 |
20120208996 | PROCESS FOR THE SYNTHESIS OF IVABRADINE AND ADDITION SALTS THEREOF WITH A PHARMACEUTICALLY ACCEPTABLE ACID - Process for the synthesis of ivabradine of formula (I): | 08-16-2012 |
20120208777 | DIOSMETIN COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM - Compounds of formula (I): | 08-16-2012 |
20120196850 | ASSOCIATION OF A SINUS NODE If CURRENT INHIBITOR AND AN ANGIOTENSIN CONVERTING ENZYME INHIBITOR, AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT - Association comprising a selective and specific sinus node I | 08-02-2012 |
20120172589 | PROCESS FOR THE SYNTHESIS OF IVABRADINE AND ADDITION SALTS THEREOF WITH A PHARMACEUTICALLY ACCEPTABLE ACID - Process for the synthesis of ivabradine of formula (I): | 07-05-2012 |
20120116112 | PROCESS FOR THE PREPARATION OF FUNCTIONALISED BENZOCYCLOBUTENES, AND APPLICATION IN THE SYNTHESIS OF IVABRADINE AND ADDITION SALTS THEREOF WITH A PHARMACEUTICALLY ACCEPTABLE ACID - Process for the preparation of compounds of formula (IV): | 05-10-2012 |
20120076856 | ORODISPERSIBLE PHARMACEUTICAL COMPOSITION OF PERINDOPRIL - The invention relates to a solid orodispersible pharmaceutical composition of perindopril, characterised in that it comprises perindopril or a pharmaceutically acceptable salt thereof and granules consisting of co-dried lactose and starch. | 03-29-2012 |
20120071462 | Dihydrobenzoxathiazepine compounds, a process for their preparation and pharmaceutical compositions containing them - Compounds of formula (I): | 03-22-2012 |
20120046287 | Dihydroindolone compounds, a process for their preparation and pharmaceutical compositions containing them - Compounds of formula (I): | 02-23-2012 |
20120029210 | Process for the synthesis of strontium ranelate and its hydrates - Process for the industrial synthesis of strontium ranelate of formula (I): | 02-02-2012 |
20110306598 | Use of the association of a sinus node if current inhibitor and an angiotensin-converting enzyme inhibitor in the treatment of heart failure - Use of the association of a selective and specific sinus node I | 12-15-2011 |
20110294999 | PROCESS FOR THE SYNTHESIS OF IVABRADINE AND ADDITION SALTS THEREOF WITH A PHARMACEUTICALLY ACCEPTABLE ACID - Process for the synthesis of ivabradine of formula (I): | 12-01-2011 |
20110288072 | Use of ivabradine for obtaining medicaments intended for the treatment of endothelial dysfunction - Use of ivabradine, or 3-{3-[{[(7S)-3,4-dimethoxybicyclo [4.2.0]octa-1,3,5-trien-7-yl]-methyl }-(methyl)-amino]-propyl}-7,8-dimethoxy-1,3,4,5 -tetrahydro-2H-3-benzazepin-2-one, its addition salts with a pharmaceutically acceptable acid and their hydrates, for obtaining a medicament intended for the treatment of endothelial dysfunction. | 11-24-2011 |
20110237644 | UBIQUITIN SPECIFIC PROTEASES RESPONSIBLE FOR MCL-1 STABILITY AND USES THEREOF - Use of a polypeptide selected from the group consisting of USP13, USP26, USP38, USP42 or USP46 as a screening tool for an agent for treating cancer. | 09-29-2011 |
20110230466 | Association of a sinus node if current inhibitor and calcium inhibitor and pharmaceutical compositions containing it - Association comprising a selective and specific sinus node I | 09-22-2011 |
20110201805 | Process for the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid - Process for the synthesis of ivabradine of formula (I): | 08-18-2011 |
20110159598 | CRYSTAL STRUCTURE OF THE CCZ-LZ DOMAIN OF NEMO - The invention relates to a crystal of the CC2-LZ domain of the NEMO protein, in which the three-dimensional structure has been determined by X-ray diffraction at a resolution of about 3.25 A. The invention also relates to methods for the crystallisation of the CC2-LZ domain. The CC2-LZ crystals and the information derived from the crystalline structures thereof are used for identifying and designing compounds interacting with CC2-LZ. | 06-30-2011 |
20110136886 | Azabicyclo[3.2.0] hept-3-yl compounds, a process for their preparation and pharmaceutical compositions containing them - Compounds of formula (I): | 06-09-2011 |
20110112104 | TRICYCLIC COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. - Compounds of formula (I): | 05-12-2011 |
20110105516 | POLYMERIZED MICELLES - Polymerised micelles comprising polymerised amphiphilic molecules obtained starting from amphiphilic molecules having one or two lipid chains each comprising one or two polymerisable moieties and linked to a polar head. | 05-05-2011 |
20110034460 | Dihydroindolone compounds, a process for their preparation and pharmaceutical compositions containing them - Compounds of formula (I): | 02-10-2011 |
20110021490 | Chromene compounds, a process for their preparationand pharmaceutical compositions containing them - The invention relates to compounds of formula (I): | 01-27-2011 |
20100330064 | 2-mercaptocyclopentanecarboxylic acid compounds, a process for their preparation and pharmaceutical compositions containing them - Compounds of formula (I): | 12-30-2010 |
20100317698 | Polysubstituted Pyridinylaminoalkylene- and Pyridinyloxyalkylene-Cyclopropanamine Compounds, a Process for Their Preparation and Pharmaceutical Compositions Containing Them - Compounds of formula (I): | 12-16-2010 |
20100286225 | DIAZENIUMDIOLATE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. - Compounds of formula (I): | 11-11-2010 |
20100267799 | Orodispersible pharmaceutical composition of perindopril - The invention relates to a solid orodispersible pharmaceutical composition of perindopril, characterised in that it comprises perindopril or a pharmaceutically acceptable salt thereof and granules consisting of co-dried lactose and starch. | 10-21-2010 |
20100267693 | Orodispersible pharmaceutical composition of ivabradine - The invention relates to a solid orodispersible pharmaceutical composition of ivabradine, characterised in that it comprises ivabradine or a pharmaceutically acceptable salt thereof and granules consisting of co-dried lactose and starch. | 10-21-2010 |
20100260840 | Orodispersible pharmaceutical composition of agomelatine - The invention relates to a solid orodispersible pharmaceutical composition of agomelatine, characterised in that it comprises agomelatine and granules consisting of co-dried lactose and starch. | 10-14-2010 |
20100249398 | Process for the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid - Process for the synthesis of ivabradine of formula (I): | 09-30-2010 |
20100249397 | Process for the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid - Process for the synthesis of ivabradine of formula (I): | 09-30-2010 |
20100240635 | Benzothiadiazepine compounds, a process for their preparation and pharmaceutical compositions containing them - Compounds of formula (I): | 09-23-2010 |
20100204276 | INDOLE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM - Compounds of formula (I): | 08-12-2010 |
20100197740 | Method of Screening Compounds Having Anti-Amyloid Properties - The invention relates to a method of screening compounds having anti-amyloid properties. The method of screening compounds that are capable of dissociating or preventing high-affinity complexes between β-amyloid peptides and nicotinic acetylcholine receptors of human cortical tissues makes it possible to rapidly identify compounds intended for the curative and/or preventive treatment of neurodegenerative diseases, especially Alzheimer's disease. | 08-05-2010 |
20100172995 | Process For Preparing A Solid Pharmaceutical Composition - The invention relates to a process for preparing a solid pharmaceutical composition of perindopril or a salt thereof which avoids a wet granulation step and results in very stable pharmaceutical compositions, like tablets. | 07-08-2010 |
20100168150 | Camptothecin Analogue Compounds, a Process for Their Preparation and Pharmaceutical Compositions Containing Them. - Compound of formula (I): | 07-01-2010 |
20100160628 | Process for the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid - Process for the synthesis of ivabradine of formula (I): | 06-24-2010 |
20100137628 | PROCESS FOR THE SYNTHESIS OF (METHOXY-1-NAPHTHYL) ACETONITRILE AND APPLICATION IN THE SYNTHESIS OF AGOMELATINE - Process for the industrial synthesis of the compound of formula (I) | 06-03-2010 |
20100119459 | Use of ivabradine as diagonstic agent in the method of coronary angiography by multislice computed tomography - Use of ivabradine, or 3-{3-[{[(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]-methyl}(methyl)amino]propyl}-7,8-dimethoxy- 1,3,4,5-tetrahydro-2H-3-benzazepin-2-one, of its addition salts with a pharmaceutically acceptable acid and of their hydrates, as a diagnostic agent in the method of coronary angiography by multislice computed tomography. | 05-13-2010 |
20100076088 | Crystalline form IV of agomelatine, a process for its preparation and pharmaceutical compositions containing it - Crystalline form IV of the compound of formula (I): | 03-25-2010 |
20100056564 | Association of an anti-atherothrombotic agent and an anti-platelet-aggregation agent - The present invention relates to a new association of an anti-atherothrombotic agent and an anti-platelet-aggregation agent. | 03-04-2010 |
20100041640 | Beta-crystalline form of ivabradine hydrochloride, a process for its preparation and pharmaceutical compositions containing it - β-Crystalline form of ivabradine of formula (I): | 02-18-2010 |
20100036165 | Process for obtaining the crystalline form V of agomelatine - Process for obtaining the crystalline form V of the compound of formula (I): | 02-11-2010 |
20100036163 | Process for the synthesis of agomelatine - Process for the industrial synthesis of the compound of formula (I) | 02-11-2010 |
20100036162 | Process for the synthesis of agomelatine - Process for the industrial synthesis of the compound of formula (I) | 02-11-2010 |
20100036161 | Process for the synthesis of agomelatine - Process for the industrial synthesis of the compound of formula (I) | 02-11-2010 |
20100016580 | Process for the preparation of functionalised benzocyclobutenes, and application in the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid - Process for the preparation of compounds of formula (IV): | 01-21-2010 |
20100009974 | Cycloalkylated benzothiadiazines, a process for their preparation and pharmaceutical compostions containing them - Compounds of formula (I): | 01-14-2010 |
20090325883 | Peptides Which Interact with Anti-Apoptotic Members of the BCL-2 Protein Family, and Uses - The invention lies within the field of seeking out and identifying new peptides which interact with anti-apoptotic members of the Bcl-2 protein family, by means of the two-hybrid system. | 12-31-2009 |
20090318682 | Process for the synthesis of 7,8-dimethoxy-1,3-dihydro-2H-3-benzazepin-2-one, and application in the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid - Process for the synthesis of the compound of formula (I): | 12-24-2009 |
20090318420 | Gamma d-crystalline form of ivabradine hydrochloride, a process for its preparation and pharmaceutical compositions containing it - A γd-Crystalline form of ivabradine hydrochloride of formula (I): | 12-24-2009 |
20090318419 | Delta-crystalline form of ivabradine hydrochloride, a process for its preparation and pharmaceutical compositions containing it - A δ-crystalline form of ivabradine hydrochloride of formula (I): | 12-24-2009 |
20090318418 | Delta d-crystalline form of ivabradine hydrochloride, a process for its preparation and pharmaceutical compositions containing it - A δd-crystalline form of ivabradine hydrochloride of formula (I): | 12-24-2009 |
20090318417 | Gamma-Crystalline form of ivabradine hydrochloride, a process for its preparation and pharmaceutical compositions containing it - A γ-Crystalline form of ivabradine hydrochloride of formula (I): | 12-24-2009 |
20090318416 | Beta d-crystalline form of ivabradine hydrochloride, a process for its preparation and pharmaceutical compositions containing it - A βd-Crystalline form of ivabradine hydrochloride of formula (I): | 12-24-2009 |
20090312389 | Azabicylic compounds, a process for their preparation and pharmaceutical compositions containing them - Compounds of formula (I): | 12-17-2009 |
20090298813 | USE OF NEUROPROTECTIVE COMPOUNDS IN OBTAINING MEDICAMENTS INTENDED FOR THE TREATMENT OF NEURODEGENERATING DISEASES - Use of neuroprotective compounds in obtaining medicaments intended for the curative treatment of neurodegenerative disease and/or the prevention of the appearance of disorders ensuing from those diseases. | 12-03-2009 |
20090274674 | Heterocyclic Oxime Compounds, Process for Their Preparation and Pharmaceutical Compositions Containing Them - Compounds of formula (I): | 11-05-2009 |
20090258883 | 1H-Indole-Pyridinecarboxamide and 1H-Indole-Piperidinecarboxamide Compounds - Compounds of formula (I): | 10-15-2009 |
20090247621 | Diosmetin compounds, a process for their preparation and pharmaceutical composition containing them - Compounds of formula (I): | 10-01-2009 |
20090239917 | Heterocyclic Cycloalkyl Compounds, a Process for their Preparation and Pharmaceutical Compositions Containing Them - Compounds of formula (I): | 09-24-2009 |
20090238870 | Dividable galenical form allowing modified release of the active ingredient - Dividable galenical form for the modified release of active ingredient, wherein the non-subdivided galenical form and a portion of said form obtained by subdivision have identical dissolution profiles. Medicaments. | 09-24-2009 |
20090215745 | Association of a sinus node If current inhibitor and a calcium inhibitor, and pharmaceutical compositions containing it - Association comprising a selective and specific sinus node I | 08-27-2009 |
20090209515 | Association of a sinus node if current inhibitor and a Beta Blocker - Association of a sinus node If current inhibitor and a β-blocker and also pharmaceutical compositions containing it. | 08-20-2009 |
20090203758 | Alpha Crystalline form of the Arginine salt of Perindopril, a Process for its Preparation and Pharmceutical Compositions Containing it. - α-crystalline form of the compound of formula (I): | 08-13-2009 |
20090186934 | Beta Crystalline form of the Arginine Salt of Perindopril, a Process for its Preparation and Pharmaceutical Compositions Containing it. - β-crystalline form of the compound of formula (I): | 07-23-2009 |
20090176794 | 1H-INDOL-1-YL-UREA COMPOUNDS - Compounds of formula (I): | 07-09-2009 |
20090131719 | Process for the synthesis of (7-methoxy-1-naphthyl) acetonitrile and its application in the synthesis of agomelatine - A process for the industrial synthesis of the compound of formula (I) | 05-21-2009 |
20090131668 | 4-oxo-4,6,7,8-Tetrahydro-pyrrolo[1,2-a]pyrazine-6-carboxamide compounds - Compound of formula (I): | 05-21-2009 |
20090124656 | Heterocyclic Oxime Compounds a Process for Their Preparation and Pharmaceutical Compositions Containing Them - Compounds of formula (I): | 05-14-2009 |
20090082578 | Process for the synthesis of strontium ranelate and its hydrates - A process for the industrial synthesis of strontium ranelate of formula (I): | 03-26-2009 |
20090082393 | New addition salts of angiotensin-converting enzyme inhibitors with no donor acids, a process for their preparation and pharmaceutical compositions containing them - Compounds of formula (I): | 03-26-2009 |
20090076030 | Piperazine compounds - A compound selected from those of formula (I): | 03-19-2009 |
20090075982 | Piperazine compounds - A compound selected from those of formula (I): | 03-19-2009 |
20090075976 | Association between an anti-atherothrombotic and an angiotensin-converting enzyme inhibitor - The present invention relates to the association of an anti-atherothrombotic and an angiotensin-converting enzyme inhibitor (ACEI), and also to pharmaceutical compositions containing them, and to methods of treating vascular complications associated with diabetes, with atherothrombotic diseases, with hyperlipidaemia, with hypertension, with chronic venous diseases, with inflammation, with metabolic syndrome associated with obesity, or with cancer, with such association. | 03-19-2009 |
20090069296 | 1,2,4,5-Tetrahydro-3H-benzazepine compounds, a process for their preparation and pharmaceutical compositions containing them - Compounds of formula (I): | 03-12-2009 |
20080312314 | Alpha crystalline form of strontium ranelate - Alpha crystalline form of strontium ranelate of formula (I): | 12-18-2008 |
20080227771 | Delta d-crystalline form of ivabradine hydrochloride, a process for its preparation and pharmaceutical compositions containing it - A δd-crystalline form of ivabradine hydrochloride of formula (I): | 09-18-2008 |
20080200450 | Use of ivabradine for obtaining medicaments intended for the treatment of endothelial dysfunction - Use of ivabradine, or 3-{3-[{[(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]-methyl}-(methyl)-amino]-propyl}-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-one, its addition salts with a pharmaceutically acceptable acid and their hydrates, for obtaining a medicament intended for the treatment of endothelial dysfunction. | 08-21-2008 |