University College Cardiff Consultants Limited Patent applications |
Patent application number | Title | Published |
20160025725 | METHOD FOR IDENTIFYING A BACTERIAL INFECTION - Method for identifying a bacterial infection The present application concerns a method for identifying the nature of a bacterial infection from a peritoneal sample, in particular, whether it is a Gram-negative or Gram-positive infection, based upon the determination of one or more cellular and/or humoral markers in a sample. | 01-28-2016 |
20150292021 | PROGNOSTIC METHODOLOGY - The invention concerns a prognostic method for determining at least one, or a combination, of the following: time to first treatment, response to treatment or overall survival for a patient presenting with a disease including or characterised by telomere shortening, comprising an assessment of the longest mean telomere length at which telomere end-end fusion events can be detected and then a determination of the mean telomere length in the fusogenic range (i.e. the range below said mean telomere length at which telomere end-end fusion events can be detected) and the subsequent use of the mean telomere length in the fusogenic range as a prognostic indicator. | 10-15-2015 |
20150252421 | METHOD FOR DIAGNOSING A NEURODEGENERATIVE DISEASE - The present invention relates to methods of assessing whether a subject has or is likely to develop a neurodegenerative disease comprising determining whether the subject has a mutation in the C9orf72 gene wherein said mutation prevents or disrupts C9orf72 expression relative to expression in a reference from subjects without the mutation. | 09-10-2015 |
20150216833 | Therapeutic for Treating Inflammatory Lung Disorders - A calcium/cation-sensing receptor (CaSR) antagonist to treat an inflammatory lung disorder is described. Methods of treatment including the antagonist, combination therapeutics including the antagonist and at least one other agent, and nebulisers or inhalers including the antagonist are also described. | 08-06-2015 |
20150119264 | DIAGNOSIS AND TREATMENT OF ALZHEIMER'S DISEASE - The invention relates to novel variants that associate with Alzheimer's disease AD and their use in kits as a means for diagnosing AD; and also their use in nucleic acid molecules or cells/cell lines for identifying novel therapeutic, label of identification means. | 04-30-2015 |
20150087542 | SCREENING METHOD FOR THE DETECTION OF CLOSTRIDIUM DIFFICILE - The invention concerns a screening method for the detection of | 03-26-2015 |
20140323774 | METHOD OF MAKING ALCOHOLS - A method of making one or more alcohols with a single hydroxy group, such as methanol and ethanol, the method comprising contacting a polyol and water with a basic catalyst. The polyol may be glycerol, for example. The '. catalyst may be magnesium oxide. | 10-30-2014 |
20140316399 | CRYOPROBE - The invention relates to a medical device, including interchangeable parts thereof, for performing corneal cell freezing wherein said device comprises an elongate member having a flow line system through which a cryogenic fluid flows to cool a cryoprobe tip which tip is fixed and comprises a concave epithelial surface contact member. | 10-23-2014 |
20140303400 | SELECTIVE OXYGENATION OF ALKANES USING OXYGEN - A process for the complete or partial oxygenation of hydrocarbons comprises contacting a C | 10-09-2014 |
20140286903 | Substituted Purine Nucleosides, Phosphoramidate and Phosphordiamidate Derivatives for Treatment if Viral Infections - This invention is directed to compounds of Formula (I) having the structure that are useful in the treatment of viral infections in mammals, particularly in humans, mediated, at least in part, by a virus in the Flaviviridae family of viruses. | 09-25-2014 |
20140216456 | DISPERSION ANAESTHETIC DEVICE - The invention concerns a cartridge for an inhalation device for delivering anaesthetic to a human or animal wherein anaesthetic in said cartridge is dispersed in an anaesthetic control release medium; an inhalation device for use with said cartridge and a formulation comprising at least one selected anaesthetic and anaesthetic control release medium. | 08-07-2014 |
20140213629 | MOLECULAR TARGETS FOR HEALING OR TREATING WOUNDS - The invention relates to at least one molecular target for healing or treating wounds and, in particular chronic, human wounds. The molecular target is PTPRK, or a protein 50% homologous therewith, and which retains the same activity as PTPRK protein. Further, the invention concerns a novel therapeutic for treating said wounds and a novel gene therapy approach, involving said molecular target, for treating said wounds. | 07-31-2014 |
20140086875 | COMPOSITION BASED ON BACILLUS SPP. AND CORRELATE GENERA AND THEIR USE IN PEST CONTROL - The objective of the current invention is the control of agricultural infestations based on alternative methods that are less aggressive to the environment and that are harmless to other invertebrates and to man; for instance biological control using bacterial strains belonging to species of the genera | 03-27-2014 |
20140030755 | MICROPLATE FOR CORRELATIVE MICROSCOPY - The invention relates to a novel multiwell array comprising a plurality of wells, the majority of which have a unique cross-sectional shape whereby each well within the array can be identified and so tracked whilst the contents of the array are investigated. The invention also concerns a computer and a programmable data storage device for use with the array and an imaging apparatus including any one or more of the afore features or aspects. | 01-30-2014 |
20130267616 | Polymerisation Method - A method of forming a polymer is provided, the method comprising: Providing a first monomer comprising one or more aromatic moieties, the first monomer comprising at least two amino groups, each of the amino groups being attached to an aromatic moiety; and contacting said first monomer with formaldehyde or a source of methylene. Polymers made by such a method and uses of such polymers are also described. | 10-10-2013 |
20130224873 | METHOD AND DEVICE FOR THE DETECTION OF SULPHUR CONTAINING SPECIES - A method is provided for detecting sulphur-containing species (such as thiophosphorous esters, in particular phosphorylating agents), in which a suspected sulphur-containing species is brought into contact with a tetrazolium compound in the presence of base, typically at a pH of at least 8. A device, kit and tetrazolium compounds for use in such a method are also disclosed. | 08-29-2013 |
20130210917 | Nitrated Lipids and Methods of Making and Using Thereof - Described herein are nitrated lipids and methods of making and using the nitrated lipids. | 08-15-2013 |
20130172433 | Polymers, Their Method of Manufacture and Use Thereof - A method for the manufacture of a polymer is provided, the method comprising: Providing a first monomer, the first monomer comprising a bicyclic diamine moiety, a first nucleophilic group provided on a carbon atom of an aromatic moiety, and a second nucleophilic group provided on a carbon atom of an aromatic moiety; Providing a bridging compound comprising at least two sites vulnerable to nucleophilic attack; and Contacting the first monomer with the bridging compound. Polymers made by said method and uses of such polymers are also disclosed. | 07-04-2013 |
20130136723 | CONNECTIVE TISSUE REPAIR - The invention concerns a homogenous population of human stem cells isolated from the full depth of human cartilage tissue and/or isolated from aged human cartilage; and uses thereof. | 05-30-2013 |
20130116134 | METHOD AND KIT FOR THE CLASSIFICATION AND PROGNOSIS OF WOUNDS - The invention relates to a method and kit for identifying chronic or acute mammalian wound tissue or for determining the prognosis of mammalian wound tissue based upon the identification of at least one key set of molecular markers or genes whose expression pattern is indicative of a given wound type and so representative of a given prognosis. | 05-09-2013 |
20130096079 | Anti-Viral Pyrimidine Nucleoside Derivatives - A compound for use in the treatment or prophylaxis of viral infections such, for example as chicken pox or shingles caused by the Varicella Zoster virus, said compound having the general formula (II): wherein X is O, S, NH or CH | 04-18-2013 |
20130096049 | THERAPEUTIC CONJUGATES - The invention concerns a novel antimicrobial peptide (AMP) polymer conjugate comprising at least one AMP, typically colistin, and a dextrin polymer wherein said dextrin polymer has a molecular weight between 5,000-60,000 g/mol and is modified by the additions of pendant groups which increase the stability of the conjugate and so delays its degradation thereby slowing the rate at which the AMP is released. | 04-18-2013 |
20130012468 | CHEMICAL COMPOUNDS - 3-(2′,3′-dideoxy-ribo-β-L-furanosyl)[2,3-d]pyrimidin-2(3H)-one derivatives comprising 6-substitutents on the base moiety are shown to have anti-viral properties, particularly with respect to vaccinia and measles. The compounds have unnatural L ribose stereochemistry. | 01-10-2013 |
20120321613 | MOLECULAR TARGETS FOR HEALING OR TREATING WOUNDS - The invention relates to at least one molecular target for healing or treating wounds and, in particular chronic, human wounds. The molecular target is nWASP or a protein 50% homolgous therewith and which retains the same activity as nWASP protein, such as WASP. Further, the invention concerns a novel therapeutic for treating said wounds and a novel gene therapy approach, involving said molecular target, for treating said wounds. | 12-20-2012 |
20120315637 | METHOD AND KIT FOR THE CLASSIFICATION AND PROGNOSIS OF CHRONIC WOUNDS - A method and kit are provided for identifying non-healing or healing chronic mammalian wound tissue or for determining the prognosis of chronic mammalian wound tissue based upon the identification of at least one key set of molecular markers or genes whose expression pattern is indicative of a given wound type and so representative of a given prognosis. | 12-13-2012 |
20120122703 | DIAGNOSIS AND TREATMENT OF ALZHEIMER'S DISEASE - The invention relates to novel variants that associate with Alzheimer's disease AD and their use in kits as a means for diagnosing AD; and also their use in nucleic acid molecules or cells/cell lines for identifying novel therapeutic, label of identification means. | 05-17-2012 |
20110306494 | COMPOSITION BASED ON BACILLUS SPP. AND CORRELATE GENERA AND THEIR USE IN PEST CONTROL - The objective of the current invention is the control of agricultural infestations based on alternative methods that are less aggressive to the environment and that are harmless to other invertebrates and to man; for instance biological control using bacterial strains belonging to species of the genera | 12-15-2011 |
20100261170 | SCREENING METHODS AND SEQUENCES RELATING THERETO - Disclosed are screening methods and sequences related thereto. Disclosed are methods for detecting mutations in the MYH gene of an individual. Also disclosed are methods of genotyping and methods of predicting for an individual the likelihood of developing certain cancers, such as colorectal cancer. | 10-14-2010 |
20100166216 | Nonlinear Signal Processing - A method of determining a signal input to a transducer from the signal output from the transducer, the method comprising receiving as input at a processing means the signal output from the transducer, processing the signal output from the transducer in dependance upon a value for the linear gain coefficient of the transducer and a value for the quadratic nonlinear coefficient of the transducer, to determine the signal input to the transducer. | 07-01-2010 |
20100028900 | SCREENING METHODS AND SEQUENCES RELATING THERETO - Disclosed are screening methods and sequences related thereto. Disclosed are methods for detecting mutations in the MYH gene of an individual. Also disclosed are methods of genotyping and methods of predicting for an individual the likelihood of developing certain cancers, such as colorectal cancer. | 02-04-2010 |
20090252705 | IL-6/IL-6R Fusion Protein - The present invention relates to a fusion protein comprising a functional IL-6 molecule and a functional DS-sIL-6R molecule. The present invention also relates to a nucleic acid encoding the fusion protein, methods of producing the fusion protein, and the use of the fusion protein in the treatment of infectious diseases and in inflammatory and immunological disorders. | 10-08-2009 |
20090004101 | Method and Means for Enhanced Pulmonary Drug Delivery - The present invention provides a method of enhancing the absorption of molecules across the airway epithelium, thereby enhancing the delivery of desired therapeutic or diagnostic agents across the airway epithelium via the systemic circulation to the target site of action. The method comprises administration of a formulation comprising a pharmaceutical composition comprising a synthetic or natural nucleoside diphosphate, nucleoside triphosphate, or dinucleoside polyphosphate, together with a pharmaceutically acceptable carrier. Preferably the nucleotide is a P2Y receptor agonist which is administered at any time during treatment with a therapeutic or diagnostic agent. A preferred embodiment is a method of administering a pharmaceutical composition comprising a P2Y receptor agonist with enhanced resistance to extracellular hydrolysis, such as dinucleoside polyphosphate compounds. | 01-01-2009 |
20080305033 | Catalysts - A catalyst effective for the direct reaction of hydrogen and oxygen to form hydrogen peroxide includes particles of gold, palladium or, preferably, gold and palladium deposited upon an acid-washed support. High selectivity to and production of hydrogen peroxide is observed, with low hydrogen peroxide decomposition. The catalysts have extended lifespan. | 12-11-2008 |
20080294069 | Ph Sensor - The invention relates to a pH sensor for use in a catheter drainage system. The invention also relates to a catheter, drainage bag or connection unit comprising the pH sensor of the present invention, methods of using the pH sensor and methods of making the pH sensor. | 11-27-2008 |
20080213784 | SCREENING METHODS AND SEQUENCES RELATING THERETO - A screening method for identifying an individual having a pre-disposition towards having a cancer is disclosed, which screening method comprises the steps of:
| 09-04-2008 |