The Arizona Board of Regents on Behalf of The University of Arizona Patent applications |
Patent application number | Title | Published |
20160073268 | A METHOD FOR IMPROVING SPECTRUM SENSING AND EFFICIENCY IN COGNITIVE WIRELESS SYSTEMS - Systems and methods for adaptive method exploits self-interference suppression (SIS) and full-duplex (FD) capabilities in cognitive radio and dynamic spectrum access (DSA) systems to enable simultaneous transmission-and-sensing (TS) or transmission-and-reception (TR) over the same frequency channel in a single operation. The adaptive methods enable secondary users or units (SUs) to switch between different modes of operation, taking into account the primary units (PUs) state, the SUs' traffic, and standards' rules. These adaptive methods significantly enhance the SU throughput and reduce the probability of colliding with PU transmissions. | 03-10-2016 |
20160067320 | Fungal Immunogens and Related Materials and Methods - The present disclosure provides immunogenic materials and methods useful for reducing the risk of fungal infections, particularly valley fever. The disclosure also provides assays for identifying compounds useful to treat valley fever, as well as methods for ameliorating the symptoms of valley fever. | 03-10-2016 |
20160022312 | MODIFIED VERESS NEEDLE FOR TENSION PNEUMOTHORAX DECOMPRESSION - Disclosed are devices and methods for treating tension pneumothorax. A needle assembly may include an outer cannula defining a lumen and having a distal end portion with a sharp bevel, and an inner cannula slidably-disposed through the lumen of the outer cannula. The inner cannula moves between an extended and retracted position and includes a blunt distal end portion configured to extend beyond the sharp bevel of the outer cannula when the inner cannula is in the extended position. The blunt distal end portion can retract within the lumen of the outer cannula when the inner cannula is in the retracted position, thereby exposing the sharp bevel. The needle assembly further includes a bias disposed inside the housing and coupled to the inner cannula. A proximal end portion of the inner cannula is configured to extend through the housing when the inner cannula is in the retracted position. | 01-28-2016 |
20150293308 | RECONFIGURABLE DIFFRACTIVE OPTICAL SWITCH - Optical switch based on a micro-mirror device such as a DMD for simultaneous switching light from N inputs to M outputs with switching times of about 10 microseconds, where N and M are generally greater than one. The mirrors of the device are oriented according to a pattern calculated based on a Fourier Transform of spatial distribution of M outputs such as to form, in diffraction of light incident on the device, an diffraction light pattern that in the output plane is substantially congruent with the spatial distribution of M outputs. The device can be configured as a modulator of amplitude and/or a modulator of phase of incident light wavefront. | 10-15-2015 |
20150288141 | MULTI-CHIP VECSEL-BASED LASER TUNABLE INDEPENDENTLY AT MULTIPLE WAVELENGTHS - A laser device capable to simultaneously generate light at multiple wavelengths that are independently (and, optionally, simultaneously) tunable without a limit of how small a spectral separation between such wavelengths can be made is enabled with the use of a laser-cavity network that (i) contains multiple spatially-distinct laser cavity portions all of which have at least one spatial region of the cavity network in common and (ii) is defined by such optical elements that prevent the intracavity amplification of light at first and second of multiple wavelengths at the expense of the same laser gain medium. Each of the distinct cavity portions contains a dedicated laser chip supporting the generation of light at a corresponding wavelength. In a special case, at least two of the multiple lasing wavelengths in the output of the device can be simultaneously and independently tuned to become equal. | 10-08-2015 |
20150226845 | ULTRASONIC/PHOTOACOUSTIC IMAGING DEVICES AND METHODS - Devices are disclosed for obtaining data of a sample, particularly data capable of being processed to produce an image of a region of the sample. An exemplary device includes a light-beam source, an acoustic-wave source, an optical element, and an acoustic detector. The optical element is transmissive to a light beam produced by the light-beam source and reflective to acoustic waves produced by the acoustic-wave source. The optical element is situated to direct the transmitted light beam and reflected acoustic wave simultaneously along an optical axis to be incident at a situs in or on a sample to cause the sample to produce acoustic echoes from the incident acoustic waves while also producing photoacoustic waves from the incident light beam photoacoustically interacting with the situs. The acoustic detector is placed to receive and detect the acoustic echoes and the photoacoustic waves from the situs. The acoustic detector can comprise one or more hydrophones exploiting the acousto-electric effect. | 08-13-2015 |
20150225696 | Methods for Efficient Immortalization Of Normal Human Cells - Methods for inducing non-clonal immortalization of normal epithelial cells by directly targeting the two main senescence barriers encountered by cultured epithelial cells. In human mammary epithelial cells (HMEC), the stress-associated stasis barrier was bypassed and the replicative senescence barrier, a consequence of critically shortened telomeres, was bypassed in post-stasis HMEC. Early passage non-clonal immortalized lines exhibited normal karyotypes. Methods of efficient HMEC immortalization, in the absence of “passenger” genomic errors, should facilitate examination of telomerase regulation, immortalization during human carcinoma progression, and methods for screening for toxic and environmental effect on progression. | 08-13-2015 |
20150221425 | MAGNETIC-CORE POLYMER-SHELL NANOCOMPOSITES WITH TUNABLE MAGNETO-OPTICAL AND/OR OPTICAL PROPERTIES - Methods are disclosed for synthesizing nanocomposite materials including ferromagnetic nanoparticles with polymer shells formed by controlled surface polymerization. The polymer shells prevent the nanoparticles from forming agglomerates and preserve the size dispersion of the nanoparticles. The nanocomposite particles can be further networked in suitable polymer hosts to tune mechanical, optical, and thermal properties of the final composite polymer system. An exemplary method includes forming a polymer shell on a nanoparticle surface by adding molecules of at least one monomer and optionally of at least one tethering agent to the nanoparticles, and then exposing to electromagnetic radiation at a wavelength selected to induce bonding between the nanoparticle and the molecules, to form a polymer shell bonded to the particle and optionally to a polymer host matrix. The nanocomposite materials can be used in various magneto-optic applications. | 08-06-2015 |
20150202040 | Buttressed Haptic - A haptic supporting an intraocular lens (IOL) in the eye permits radial tension from ciliary muscle relaxation rather than contraction to alter the lens power. The IOL is supported by the overlying tissue in the eye such as iris root, sclera and ciliary process, so that anterior and posterior forces on IOL are balanced, and buckling or displacement of lens in the eye or haptic is reduced or prevented. The haptic is of a thickness so as to increase stiffness and to reduce or prevent IOL buckling or displacement. | 07-23-2015 |
20150194242 | Electrostatic Coating with Metallic Nanoparticles by Intrinsic Particle to Surface Interaction - Described are methods for forming thin, pinhole-free conformal metal layers on both conducting and non-conducting surfaces. The formed metal films are useful as seed layers for further deposition of metal using conventional techniques like electroplating, and provide specific advantages for non-conducting surfaces, which are otherwise unsuitable for electroplating without the presence of the formed metal films. Unlike electroplating, the disclosed methods, however, do not require the presence of a voltage or external electric field at the surface, but form the metal films through an electroless technique using electrostatic interactions between negatively charged nanoparticles and a positively charged surface. In addition, the disclosed methods are compatible with solution phase processing and, thus, eliminate the need to transfer the surfaces into a vacuum chamber for a chemical or physical vapor deposition to form a metal layer. | 07-09-2015 |
20150185151 | FORMULAIC IMAGING FOR TISSUE DIAGNOSIS - Methods for reliable identification of low-contrast lesions within a tissue of a subject comprise delivering an excitation signal to the tissue, wherein the excitation signal is selected to stimulate tissue to produce autofluorescence and/or reflectance. The autofluorescence and/or reflectance is detected, and ratiometric images are produced based on the autofluorescence and/or reflectance images. An imaging system is provided which is configured to carry out such methods, irradiating tissue at a various possible excitation wavelengths, such as UV excitation wavelengths below 300 nm, to elicit fluorescence from specific native fluorophores. | 07-02-2015 |
20150184225 | ELECTROKINETIC POLYMERASE CHAIN REACTION (PCR) DEVICES AND METHODS - Described herein are microfluidic diagnostic methods and devices using electrokinetic modules for the isolation of targets (e.g., cells, bacteria, biomolecules) from biological samples, PCR amplification of DNA isolated from the targets, and real-time quantification of the amplified DNA using impedance sensing. Sample preparation, PCR amplification, and impedance sensing are thus performed using a single integrated platform. | 07-02-2015 |
20150126610 | REDOX-DIRECTED CHELATORS TARGETING INTRACELLULAR METAL IONS - The present invention provides redox-activated chelators and methods for using the same to treat cancer. In one particular embodiment, the redox-activated chelator is of the formula: | 05-07-2015 |
20150104798 | MICRODROPLET-MANIPULATION SYSTEMS AND METHODS FOR AUTOMATED EXECUTION OF MOLECULAR BIOLOGICAL PROTOCOLS - Disclosed herein are automated systems for performing various biochemical and molecular biological procedures, including processor-controlled execution of protocols involving multiple steps performed in, on, or with liquid microdroplets. Example protocols are the various Polymerase Chain Reaction (PCR) protocols, but the subject systems are not limited to performing PCR protocols. Formation of a microdroplet of the sample for use in the described systems is achieved by bringing an amount of the sample into contact with a hydrophobic milieu, such as a superhydrophobic surface or hydrophobic liquid. | 04-16-2015 |
20150103140 | VOLUME HOLOGRAPHIC IMAGING SYSTEM (VHIS) ENDOSCOPE - Provided are modular volume holographic imaging system (VHIS) endoscopic systems, comprising: an endoscope attachment module having a microscope objective lens, a single or cascaded compensated relay system configured to preserve an optical wavefront for use with a single or multiplexed volume hologram to select wavefronts originating from different object depths, and a system aperture; and a handle module configured to be reversibly attachable for operative communication with the endoscope attachment module, and having a beam splitter; a relay having adjustable spacing for object space focus compensation, and a single or multiplexed volume hologram suitable in operation to select wavefronts originating from different object depths, and wherein the handle module is further configured for operative communication with an illumination source and imaging optics. Preferably, an illumination module and an imaging module are configured to be in operative, reversibly attachable communication with the handle module. Flexible tip endoscopic embodiments are provided. | 04-16-2015 |
20150080571 | COMPOUNDS HAVING LOW IONIZATION ENERGY - The present invention provides compounds that are soluble in a non-polar solvent and having a low ionization energy and negative oxidation potentials in tetrahydrofuran (THF). The present invention also provides a method for producing and using the same. | 03-19-2015 |
20150072357 | Cholesteryl Succinyl Silane Bound Proteins and Methods For Producing and Using the Same - The present invention provides a various three-dimensional polymeric scaffold and methods for producing and using the same. In one embodiment, the three-dimensional polymeric scaffold is used to promote cell migration. Yet in another embodiment, the three-dimensional polymeric scaffold comprises enhanced surface functionalization. In one particular embodiment, the polymeric scaffold comprises a plurality of polymer layers, wherein each polymer layer comprises microchannels. Still in another particular embodiment, the composition comprises a fibrous cholesteryl succinyl silane. Yet in another particular embodiment, a polymer comprising cholesteryl succinyl silane attached (e.g., hybridized) to its surface is provided. | 03-12-2015 |
20150045407 | MTK1-ACTIN INHIBITORS AND METHODS OF USE - One aspect of the invention provides a method for treating a clinical condition associated with inappropriate or abnormal activation of HER3/ErbB3. In some embodiments, the method of the invention inhibits interaction between MTK1 and actin. | 02-12-2015 |
20150037877 | Method of Simultaneous Frequency-Sweeping Lifetime Measurements on Multiple Excitation Wavelengths - A fast fluorescence lifetime microscopic system images FRET between multiple labels in live cells and deep tissue, using a quantitative analysis method to reconstruct the molecular machinery behind the multiplexed FRET phenomenon. The system measures fluorescence lifetime, intensity and anisotropy as images of excitation-emission matrices (EEM) in real time and high speed within a single image scan, performs high-resolution deep-penetrating 3D FRET imaging in live samples, and fully analyzes all possible photon pathways of multiplexed FRET. The system provides a way for systematic and dynamic imaging of biochemical networks in cells, tissue and live animals, which will help to understand mechanisms of genetic disorders, cancers, and more. | 02-05-2015 |
20140378294 | Graphene-Reinforced Ceramic Composites and Uses Therefor - The disclosure provides novel graphene-reinforced ceramic composites and methods for making such composite materials. | 12-25-2014 |
20140356642 | METALLIC MAGNETIC POWDER AND MANUFACTURING METHOD OF THE SAME, MAGNETIC PAINTING, MAGNETIC POWDER FOR MAGNETIC THERAPY, AND MAGNETIC RECORDING MEDIUM - A metallic magnetic powder where a primary particle of each metallic magnetic particle is a powder without forming an aggregate, and a method of making the same that includes manufacturing a metallic magnetic powder constituted of metallic magnetic particles, containing a metallic magnetic phase, with Fe, or Fe and Co as main components, rare earth elements or yttrium and one or more non-magnetic components removing the non-magnetic component from the metallic magnetic with a reducing agent, while making a complexing agent exist for forming a complex with the non-magnetic component in water; oxidizing the metallic magnetic particle with the non-magnetic component removed; substituting water adhered to the oxidized metallic magnetic particle with an organic solvent; and coating the surface of the metallic magnetic particle with an organic matter different from the organic solvent, while maintaining a wet condition of the metallic magnetic particle with the organic solvent adhered thereto. | 12-04-2014 |
20140301535 | Gamma Ray Imaging Systems And Methods - A system for imaging a gamma source includes a pixelated Compton scattering layer, for Compton scattering of gamma photons emitted by the gamma source, and a non-pixelated full-energy detector for detecting at least a portion of Compton scattered gamma photons geometrically encoded by a coded aperture positioned between the pixelated Compton scattering layer and the full-energy detector at a distance from the pixelated Compton scattering layer. A method for imaging a gamma source includes (a) detecting coincidence events, each including Compton scattering in a pixelated Compton scattering layer, and transmission to a non-pixelated full-energy detector of a Compton scattered gamma photon transmitted through a coded aperture located at a distance from the pixelated Compton scattering layer, and (b) determining an image of the gamma source from the detection of the coincidence events. | 10-09-2014 |
20140271574 | METHODS AND COMPOSITIONS FOR TREATING CONGESTIVE HEART FAILURE - Compositions and methods for treating congestive heart failure are provided herein. | 09-18-2014 |
20140180549 | AUTOMATED MACHINE FOR SELECTIVE IN SITU MANIPULATION OF PLANTS - Disclosed herein are systems for identifying a plant in a field with pixel-level precision and taking an action on the identified plant, also with pixel level precision. The disclosed systems can include multiple implements, enabling the performance of multiple tasks on an identified plant or associated area of soil. Methods of using the described systems for automated thinning, weeding and spot spraying crops are also disclosed. | 06-26-2014 |
20140163389 | IN VIVO DETECTION OF EOSINOPHILS - Snapshot spectral images viewing down the axis of the esophagus are processed to identify eosinophils. The snapshot images are based on fluorescence emitted in response to excitation optical radiation at two or more wavelengths. Ratio of spectral powers between snapshot images can be used in identification. In some examples, a relative abundance or density eosinophils is obtained, and processed to perform an in vivo assessment of tissue, such as esophageal tissue. | 06-12-2014 |
20140162262 | Method and Device for Generating a Tunable Array of Fluid Gradients - Provided herein are devices and methods for generating microfluidic gradients, including an array of unique microfluidic gradients within an array of microchannels. Fluids within conduits are mixed in an intersection region to generate a mixed flow stream in a source reservoir channel that provides a gradient that varies with axial distance from the intersection region. Microchannels having an inlet connected to the source reservoir channel are configured to provide a microfluidic gradient in the microchannel. An outlet end of the microchannel is connected to a sink reservoir channel. By varying the ratio of fluid flow rates from the fluid conduits, the microchannel gradients are tuned. In this manner, a large number of unique gradients or array of microfluidic gradients is provided, wherein the gradient can be any number of physical or chemical parameters, including concentrations and physical fluid properties. | 06-12-2014 |
20140151545 | Sensitive Ion Detection Device and Method for Analysis of Compounds as Vapors in Gases - An ion mobility spectrometer (IMS) for the detection of trace gaseous molecular compounds dissolved or suspended in a carrier gas, particularly in ambient air, without preconcentration or the trapping of analyte particles. The IMS of the invention comprises an ionization volume of greater than 5 cm | 06-05-2014 |
20140142287 | SYNTHESIS OF CARBOHYDRATE-BASED SURFACTANTS - The present invention provides carbohydrate-based surfactants and methods for producing the same. Methods for producing carbohydrate-based surfactants include using a glycosylation promoter to link a carbohydrate or its derivative to a hydrophobic compound. | 05-22-2014 |
20140130843 | HOLOGRAPHIC DIFFRACTION-THROUGH-APERTURE SPECTRUM SPLITTING SYSTEM AND METHOD - An apparatus for obtaining energy from a polychromatic energy source that emits radiation in a first and a second wavelength band comprises a reflector or an energy receiver having an aperture therein; and a holographic lens that diffracts and focuses the radiation within the first wavelength band from the energy source through said aperture towards a first energy receiver, and transmits the radiation within the second wavelength band from the energy source to the reflector or energy receiver. If a reflector is used, the reflector reflects the radiation transmitted by the holographic lens towards a second energy receiver. | 05-15-2014 |
20130329304 | HEAD-MOUNTED PROJECTION DISPLAY USING REFLECTIVE MICRODISPLAYS - The present invention relates generally to a head-mounted projection display, and more particularly, but not exclusively to a polarized head-mounted projection display including a light engine and a compact, high-performance projection lens for use with reflective microdisplays. | 12-12-2013 |
20130329283 | CATADIOPTRIC OPTICAL SYSTEM WITH TOTAL INTERNAL REFLECTION FOR HIGH NUMERICAL APERTURE IMAGING - A catadioptric optical system includes, in order from an object side to an image side and arranged along an optical axis, a first catadioptric unit, a second catadioptric unit disposed in axial alignment with the first catadioptric unit and with a space therebetween; and a lens group disposed in axial alignment with the first and second catadioptric optical units. Light rays arriving from an object plane undergo a first reflection at the image-side surface of the first catadioptric optical unit, a second reflection at the object-side surface of the first catadioptric optical unit, a third reflection at the image-side surface of the second catadioptric optical unit, and a fourth reflection at the object-side surface of the second catadioptric optical unit. Advantageously, the sum the outward Petzval curvatures is cancelled out by the sum of inward Petzval curvatures. | 12-12-2013 |
20130329226 | SYSTEM WITH DIFFUSED ILLUMINATION FOR TOMOGRAPHIC IMAGING - The present invention provides an apparatus for tomographic imaging of an object. The apparatus includes a light unit configured to generate illumination, which comprises coherent light and has random phase distribution in a plane perpendicular to an optical axis, for illuminating an object, a coupler which combines a reference beam and an object beam for an interference, a shifter configured to shift relative phase difference between the object light and the reference coherent light, a detector configured to detect an interference caused by the reference coherent light and object light for the each phase, and a processor configured to calculate an optical propagation based on the detected interference for the each phase. | 12-12-2013 |
20130286403 | INTERFEROMETRIC METHOD AND DIGITAL HOLOGRAPHIC MICROSCOPE - An interferometric method for detecting information about a sample includes emitting a laser beam; splitting the laser beam into a reference beam and an object beam; transmitting the object beam through the sample in an incident angle; combining the reference beam with the object beam passed through the sample to form an interference pattern; detecting the interference pattern, and non-linearly scanning the object beam in order to detect a plurality of interference patterns. | 10-31-2013 |
20130258429 | CONFOCAL RAINBOW VOLUME HOLOGRAPHIC IMAGING SYSTEM - A confocal rainbow holographic imaging system and hologram fabrication method. The system employs a multi-spectral light source, a multiple grating volume hologram and a dual pass illumination and imaging pathway which provide for depth sectioning of an object, coverage of the full FOV of the system, and high lateral and depth resolution. Dual matched holograms are used to provide a high image contrast ratio. A method for fabricating the holograms employ a novel combination of design tools is also provided. | 10-03-2013 |
20130184143 | Graphene-Reinforced Ceramic Composites and Uses Therefor - The disclosure provides novel graphene-reinforced ceramic composites and methods for making such composite materials. | 07-18-2013 |
20130182224 | HOLOGRAPHIC ADAPTIVE SEE-THROUGH PHOROPTER - A phoropter having a line of sight for a viewer to see through comprises a lens system in the line of sight, wherein a shape or focal length of at least one lens in the lens system is controllable by means of an electrical signal, electrical field or current. Wavefront sensors of the phoropter detect local tilts of light wavefronts emerging from the eye and generate output signals that are used for controlling the shape or focal length of the at least one lens. Holographic or diffractive elements are used to collect light scattered from an eye of the viewer and image the scattered light to the wavefront sensors. Preferably one or more of the holographic or diffractive elements are away from the line of sight of the viewer. To use the phoropter, light is passed to the lens system, and light scattered by the eye is collected by the holographic or diffractive elements and imaged onto the wavefront sensors. | 07-18-2013 |
20130162796 | METHODS AND APPARATUS FOR IMAGING, DETECTING, AND MONITORING SURFICIAL AND SUBDERMAL INFLAMMATION - Described are imaging apparatus and methods for imaging an area of interest, such as selected regions on a surface of a human or other living subject, by thermal and non-thermal means. Methods of using the apparatus to detect and monitor wounds in an area of interest on a subject are also described. The apparatus and methods have particular utility for detection and monitoring of ulcerations and general wound degradations, as well as of conditions that could result in formation of such lesions. | 06-27-2013 |
20130149710 | MICRODROPLET-MANIPULATION SYSTEMS AND METHODS FOR AUTOMATED EXECUTION OF MOLECULAR BIOLOGICAL PROTOCOLS - Disclosed herein are automated systems for performing various biochemical and molecular biological procedures, including processor-controlled execution of protocols involving multiple steps performed in, on, or with liquid microdroplets. Example protocols are the various Polymerase Chain Reaction (PCR) protocols, but the subject systems are not limited to performing PCR protocols. Formation of a microdroplet of the sample for use in the described systems is achieved by bringing an amount of the sample into contact with a hydrophobic milieu, such as a superhydrophobic surface or hydrophobic liquid. | 06-13-2013 |
20130110235 | ACCOMMODATING INTRAOCULAR LENS WITH DEFORMABLE MATERIAL | 05-02-2013 |
20130069011 | DOPED-CARBON NANO-ARCHITECTURED STRUCTURES AND METHODS FOR FABRICATING SAME - In an exemplary method, a nano-architectured carbon structure is fabricated by forming a unit (e.g., a film) of a liquid carbon-containing starting material and at least one dopant. A surface of the unit is nano-molded using a durable mold that is pre-formed with a pattern of nano-concavities corresponding to a desired pattern of nano-features to be formed by the mold on the surface of the unit. After nano-molding the surface of the unit, the first unit is stabilized to render the unit and its formed nano-structures capable of surviving downstream steps. The mold is removed from the first surface to form a nano-molded surface of a carbonization precursor. The precursor is carbonized in an inert-gas atmosphere at a suitable high temperature to form a corresponding nano-architectured carbon structure. A principal use of the nano-architectured carbon structure is a carbon electrode used in, e.g., Li-ion batteries, supercapacitors, and battery-supercapacitor hybrid devices. | 03-21-2013 |
20130065863 | NITROXYL (HNO) RELEASING COMPOUNDS AND USES THEREOF IN TREATING DISEASES - Disclosed is a compound of the formula (I) or a pharmaceutically acceptable salt thereof: (I) in which R | 03-14-2013 |
20130012793 | In-Vivo Optical Sensor - An apparatus for determining an optical property of a set of cells is described. The apparatus may include a light source for providing a light signal, a light-conditioning unit configured to condition the light signal, and a diffractive structure. The diffractive structure may be configured to receive the conditioned light signal and produce diffracted light having plasmon-resonance properties and an angular spectrum. The angular spectrum may correspond to the set of cells when the set of cells are within a threshold distance from the diffractive structure. The apparatus further includes a light-collecting unit for collecting the diffracted light. | 01-10-2013 |
20120307326 | SYSTEM, METHOD AND APPARATUS FOR PHASE CONTRAST ENHANCED MULTIPLEXING OF IMAGES - A volume holographic imaging system, apparatus, and/or method enables the projection of a two-dimensional (2D) slice of a four-dimensional (4D) probing object A 4D probing source object is illuminated to emit or scatter an optical field A holographic element having one or more recorded holograms receives and diffracts the optical field into a diffracted plane beam having spectral information A 4-ftelecentπc relay system includes a pupil filter on the relayed conjugate plane of the volume hologram and images the pupil of the volume hologram onto the front focal plane of the collector lens A collector lens focuses the diffracted plane beam to a 2D slice of the 4D probing source object The focused 2D slice is projected onto a 2D imaging plane The holographic element may have multiple multiplexed holograms that are arranged to diffract light from the corresponding slice of the 4D probing source object. | 12-06-2012 |
20120268309 | VIRTUAL APERTURE RADAR (VAR) IMAGING - Virtual Aperture Radar (VAR) imaging provides terminal phase radar imaging for an airborne weapon that can resolve multiple closely-spaced or highly correlated scatterers on a given target with a single pulse to provide an aimpoint update at a useful range to target without training data and without requiring a large aperture antenna. VAR imaging exploits the sparse, dominant-scatterer nature of man-made targets. The array manifold is constructed with a large number of basis functions that are parameterized by range or angle (or both) to target. The number of basis functions extends the capability to resolve scatterers beyond the Rayleigh resolution. However, this also makes the manifold underdetermined. A sparse reconstruction technique that places a sparsity constraint on the number of scatterers is used to solve the manifold to uniquely identify the ranges or angles to the scatterers on the target. These updates are passed to the weapon's guidance system, which in turn generates command signals to actuate aerodynamic surfaces such as fins or canards to steer the weapon to the target. | 10-25-2012 |
20120238700 | METHOD FOR PRODUCING METAL OXIDE ORGANIC COMPOUND COMPOSITE - A method for obtaining a metal oxide organic compound composite includes dissolving a hydrated yttrium chloride and an epoxide in a solvent, and obtaining a gel including the metal oxide organic compound composite. | 09-20-2012 |
20120027033 | MULTI-SEGMENT ALL-FIBER LASER - A multi-segment all-fiber laser is provided. The device includes a first active fiber laser segment, a first grating, a second grating, and a gain-phase coupling fiber segment arranged between the first and second gratings, said gain-phase coupling segment providing coupling of gain and phase between said first and second gratings. | 02-02-2012 |
20120000726 | SOLID-STATE ACOUSTIC METAMATERIAL AND METHOD OF USING SAME TO FOCUS SOUND - A phonemic crystal is made of a first solid medium having a first density and a substantially periodic array of structures disposed in the first medium, the structures being made of a second solid medium having a second density different from the first density. The first medium has a speed of propagation of longitudinal sound waves and a speed of propagation of transverse sound waves, the speed of propagation of longitudinal sound waves being approximately that of a fluid, and the speed of the propagation of transverse sound waves being smaller than the speed of propagation of longitudinal sound waves. | 01-05-2012 |
20110292335 | DIFFRACTIVE TRIFOCAL LENS - A diffractive multifocal lens is disclosed, comprising an optical element having at least one diffractive surface, the surface profile comprising a plurality of annular concentric zones. The optical thickness of the surface profile changes monotonically with radius within each zone, while a distinct step in optical thickness at the junction between adjacent zones defines a step height. The step heights for respective zones may differ from one zone to another periodically so as to tailor diffraction order efficiencies of the optical element. In one example of a trifocal lens, step heights alternate between two values, the even-numbered step heights being lower than the odd-numbered step heights. By plotting a topographical representation of the diffraction efficiencies resulting from such a surface profile, step heights may be optimized to direct a desired level of light power into the diffraction orders corresponding to near, intermediate, and distance vision, thereby optimizing the performance of the multifocal lens. | 12-01-2011 |
20110245175 | INHIBITING INTERACTION BETWEEN THE HIF-1ALPHA AND p300/CBP WITH HYDROGEN BOND SURROGATE-BASED - The present invention relates to peptides having one or more stable, internally constrained α-helices, and that include a sequence that mimics at least a portion of the C-terminal transactivation domain of HIF-1α. Also disclosed are pharmaceutical compositions containing these peptides and methods of using these peptides, for example to reduce gene transcription, treat or prevent disorders mediated by interaction of HIF-1α with CREB-binding protein and/or p300, reduce or prevent angiogenesis in a tissue, induce apoptosis, decrease cell survival and/or proliferation, and identify potential ligands of CREB-binding protein and/or p300. | 10-06-2011 |
20110236181 | VERTICAL AXIS WIND TURBINE - A vertical axis wind turbine comprises upper and lower rotor blades and upper and lower bearing assemblies. Horizontal members connect the upper rotor blades to the upper bearing assembly and the lower blades connect the upper rotor blades to the lower bearing assembly. The upper rotor blades can be arranged vertically or non-vertically. In non-vertical arrangements, the upper rotor blades can be twisted or swept back in a straight manner. The turbine can be self-supporting with a need for a continuous vertical axis connecting the bearing assemblies. Sweeping jet actuators are incorporated into the rotor blades to deliver oscillating air jets to surfaces of the rotor blades to delay occurrence of dynamic stall. Conduits in the blades can deliver pressurized flow of air to the actuators. The turbine can be supported by a structure that can exerts only horizontal and/or lifting forces on the rotor blade assembly to reduce the load on the lower bearing. | 09-29-2011 |
20110199658 | System and method for synchronizing a spatial light modulator with a pulsed laser to record a hologram at the repetition rate of the pulsed laser - A system and method that synchronizes a spatial light modulator (SLM) with a pulsed laser to record a hologram at the repetition rate of the pulsed laser for applications including holographic displays and data storage. The color channel capability of a SLM is utilized to effectively increase the write throughput when the pulsed laser repetition rate LR exceeds the SLM's image refresh rate R. The hogels are encoded on the color channels and concatenated to form a sequence of color images such that the write throughput is equal to the repetition rate LR up to a maximum of N*R. The invention effectively extends the capability and continued viability of existing inexpensive SLMs. | 08-18-2011 |
20110134944 | EFFICIENT PULSE LASER LIGHT GENERATION AND DEVICES USING THE SAME - A time delay is introduced in the optical path of the light pulse at fundamental wavelength relative to that for the fourth harmonic light pulse in a set up for generating the 5 | 06-09-2011 |
20110101938 | ADAPTIVE-GAIN STEP-UP/DOWN SWITCHED-CAPACITOR DC/DC CONVERTERS - A switched-capacitor DC-DC converter has a reconfigurable power stage with variable gain ratio and/or interleaving regulation for low ripple voltage, fast load transient operation, variable output voltage and high efficiency. Since the power stage has multiple switches per capacitor, the converter exploits reconfigurable characteristics of the power stage for fast dynamic control and adaptive pulse control for tight and efficient voltage regulation. | 05-05-2011 |
20100249235 | ADMINISTRATION OF 3,5-DIIODOTHYROPROPIONIC ACID FOR STIMULATING WEIGHT LOSS, AND/OR LOWERING TRIGLYCERIDE LEVELS, AND/OR TREATMENT OF METABOLIC SYNDROME - The invention provides methods and compositions for stimulating weight loss or lowering triglyceride levels in an individual in need thereof. In methods of the invention, a pharmaceutical composition comprising a therapeutically effective amount of DITPA, and optionally one or a plurality of lipid lowering agents, is administered to an individual to stimulate weight loss, lower triglyceride and/or lipoprotein levels, and/or to treat one or more symptoms of metabolic syndrome. | 09-30-2010 |
20100002581 | Method for Inter-Router Dual-Function Energy- and Area-Efficient Links for Network-on-Chips - The present invention provides methods for connecting routers and transmitting data along inter-router links within Nework-on-Chip (NoC) architectures. | 01-07-2010 |
20090285821 | Campylobacter Pilus Protein, Compositions and Methods - The present disclosure provides coding and amino acid sequences for a | 11-19-2009 |
20090270377 | COMBINATION CANCER CHEMOTHERAPY - Provided is a method for improving treatment of a neoplastic condition by combining a therapeutically effective amount of a polyADP-ribose polymerase inhibitor with a therapeutically effective amount of a compound which triggers the release of nucleolin from the G-quadruplexes in rDNA. As specifically exemplified, the compound which increases nucleolin binding is a substituted quinobenzoxazine analog, for example CX-3543. | 10-29-2009 |
20090252887 | SYSTEM AND METHOD FOR GROWING NANOTUBES WITH A SPECIFIED ISOTOPE COMPOSITION VIA ION IMPLANTATION USING A CATALYTIC TRANSMEMBRANE - An ion source(s) is configured to generate ions from one or more elements including a plurality of different isotopes or unique molecular combinations of two or more different isotopes from at least one of the selected elements. A selection filter(s) directs a subset of the ions onto a catalytic transmembrane to grow nanotubes of a specific isotope composition on the opposite side of the transmembrane. The nanotubes may be uniformly or selectively doped with dopant atoms. A controller can configure the selection filter(s) to sequentially pass different subsets of ions to form isotope, molecular or element junctions in the growing nanotubes. | 10-08-2009 |
20090220569 | Prevascularized Constructs for Implantation to Provide Blood Perfusion - This application discloses methods and materials for preparing functional microvascular beds in the laboratory. These prevascularized constructs can be used to vascularize engineered tissue constructs or to revascularize damaged or diseased tissues or organs following implantation. The prevascularized constructs may also deliver genetically engineered gene products to the bloodstream. | 09-03-2009 |
20090170069 | Cell free methods for detecting protein-ligand binding - Provided are rapid and sensitive cell-free assay methods for detecting and/or measuring specific bimolecular or higher order interactions via reassembly of a split monomeric reporter protein, and methods of detecting or identifying modulators of such interactions by the effect on the signal provided by the reassembled split reporter protein. This methodology is adaptable to protein-protein, protein-peptide, protein-nucleic acid, protein-methylated or nonmethylated nucleic acid and other small or large molecule ligands and binding proteins. | 07-02-2009 |
20080222754 | Methods of Modulating Glucosinolate Production in Plants - The present invention relates to methods for modulating glucosinolate production in plants, specifically by modulating CYP83A1 expression. The present invention also relates to transgenic plants that over-express and underexpress CYP83A1. | 09-11-2008 |