Ajinomoto Co., Inc. Patent applications |
Patent application number | Title | Published |
20160139134 | METHOD FOR ANALYSIS OF COMPOUNDS WITH AMINO GROUP AND ANALYTICAL REAGENT THEREFOR - The present invention provides a method for the analysis of a compound with amino group (e.g., an amino acid or peptide) contained in a sample and convenient manner with a high sensitivity. The compound with amino group in a sample containing the compound with amino group is labeled with a specific carbamate compound such as p-trimethylammonium anilyl-N-hydroxysuccinimidyl carbamate iodide to enhance the selectivity and sensitivity. The present invention is preferably used in conjunction with mass spectrometry such as MS/MS method to facilitate quantitative analysis. The present invention further provides labeling reagents for mass spectrometry. | 05-19-2016 |
20160137633 | PHARMACEUTICAL COMPOSITION FOR TREATING DIABETES - Provided is a compound represented by the following general formula (I), or a pharmaceutically acceptable salt thereof. This novel compound has a glycogen-synthase activation ability, but activates a receptor PPAR to a low degree and is highly safe. | 05-19-2016 |
20160130618 | Method for Manufacturing Useful Substance - A method for producing an objective substance is provided. An objective substance is produced by culturing a microorganism which has been modified so that the activity of a dicarboxylic acid exporter protein is reduced in a medium, and collecting the objective substance from the medium. | 05-12-2016 |
20160101091 | ALKYLAMINE DERIVATIVE - A composition containing a compound represented by General Formula (I) below (see the definition in the specification for the symbols in the formula) or a salt thereof has an excellent CaSR agonistic effect and provides a pharmaceutical agent, a CaSR agonistic agent, a prophylactic or therapeutic agent for a disease that can be ameliorated through CaSR activation as well as seasonings and an agent for imparting kokumi. | 04-14-2016 |
20160082009 | PHARMACEUTICAL PREPARATION COMPRISING PHENYLALANINE DERIVATIVE - The disclosed pharmaceutical preparation comprises a compound represented by the chemical formula (A) or a pharmaceutically acceptable salt thereof, which is dispersed in a matrix consisting of a water-soluble high molecular weight substance; and Crospovidone: | 03-24-2016 |
20160076033 | MORPHOLINO OLIGONUCLEOTIDE MANUFACTURING METHOD - Using a morpholino nucleotide wherein 5′-hydroxy group or a hydroxy group present on the substituent of the 5′-hydroxy group is protected by a protecting group having an alkyl group having not less than 10 and not more than 300 carbon atoms and/or an alkenyl group having not less than 10 and not more than 300 carbon atoms as a starting material, a method capable of efficiently producing the morpholino oligonucleotide in a high yield by a liquid phase synthesis can be provided. | 03-17-2016 |
20160075993 | MEDIUM FOR CULTURING STEM CELLS - Culture media, which contain albumin carrying a reduced amount of fatty acid, are useful for culturing stem cells. | 03-17-2016 |
20160074304 | GELLANT - The present invention provides a novel gellant capable of favorably gelatinizing an oily base. | 03-17-2016 |
20160060640 | Coryneform Bacterium and Method for Producing Heterologous Fusion Proteins - The present invention provides a coryneform bacterium having an ability to produce a heterologous fusion protein by secretory production, which has been modified to express a genetic construct for secretory production of the heterologous fusion protein encoding at least a heterologous fusion protein comprising an extein and an intein having an activity of acyl rearrangement. The method for producing proteins modified at the C-terminus is also provided. | 03-03-2016 |
20160060234 | CYSTEINE DERIVATIVE - Cysteine compounds represented by the following formula | 03-03-2016 |
20160060198 | DIPHENYLMETHANE COMPOUND - The present invention aims to provide a compound superior in broad utility and stability, which is useful as a protecting reagent (anchor) of amino acid and/or peptide in liquid phase synthesis and the like of a peptide having a C-terminal etc., which are of a carboxamide (—CONHR)-type, an organic synthesis reaction method (particularly peptide liquid phase synthesis method) using the compound, and a kit for peptide liquid phase synthesis containing the compound, and has found that the object can be achieved by a particular compound having a diphenylmethane skeleton. | 03-03-2016 |
20160058734 | HETEROARYLCARBOXYLIC ACID ESTER DERIVATIVE - Compounds represented by the following formula (I); | 03-03-2016 |
20160046592 | PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF DIABETES - An object is to provide a novel compound which has a glycogen synthase activation ability, but activates a receptor PPAR to a low degree and is highly safe. Provided is a compound represented by the following general formula (I) or a pharmaceutically acceptable salt thereof: | 02-18-2016 |
20160026770 | Method of evaluating lifestyle-related disease indicator, lifestyle-related disease indicator-evaluating apparatus, lifestyle-related disease indicator-evaluating method, lifestyle-related disease indicator-evaluating program product, lifestyle-related disease indicator-evaluating system, and information communication terminal apparatus - A method of evaluating lifestyle-related disease indicator includes (i) an obtaining step of obtaining amino acid concentration data on concentration values of amino acids in blood collected from a subject to be evaluated and (ii) an evaluating step of evaluating a state of an indicator of lifestyle-related disease for the subject using the concentration values of the amino acids of Gly and Tyr included in the amino acid concentration data of the subject obtained at the obtaining step. | 01-28-2016 |
20160024248 | POLYESTER COMPOUND - Polyester compounds obtained by reaction of a compound represented by formula (1): | 01-28-2016 |
20160024247 | POLYESTER COMPOUND - Polyester compounds obtained by reaction of a compound represented by formula (1): | 01-28-2016 |
20160024143 | DEPROTECTION METHOD - The present invention provides a method of efficiently deprotecting a protected organic compound by catalytic hydrogenation. Specifically, the present invention provides a method of deprotecting an organic compound having at least one functional group selected from the group consisting of a carboxy group, an amino group and a hydroxy group, which is protected by a protecting group represented by the formula (I): | 01-28-2016 |
20160017375 | METHOD FOR COLLECTING ISOPRENOID COMPOUND CONTAINED IN FERMENTED GAS, AND METHOD FOR PRODUCING PURIFIED ISOPRENOID COMPOUND - Methods include contacting a fermented gas including isoprenoid compound with a porous adsorbent and desorbing isoprenoid compound adsorbed on the porous adsorbent. The fermented gas may be obtained by culturing a microorganism having an ability to produce isoprenoid compound. | 01-21-2016 |
20160016867 | METHOD FOR COLLECTING ISOPRENE CONTAINED IN FERMENTED GAS, AND METHOD FOR PRODUCING PURIFIED ISOPRENE - Methods include contacting a fermented gas including isoprene with a porous adsorbent and desorbing isoprene adsorbed on the porous adsorbent. The fermented gas may be obtained by culturing a microorganism having an ability to produce isoprene. | 01-21-2016 |
20160002610 | Modified Glycine Oxidase - The present invention provides a novel enzyme and methods of using the enzyme for measuring glycine concentration. Specifically, the present invention provides an enzyme in which at least one amino acid residue is mutated so as to improve a property of a glycine oxidase which is associated with the measurement of glycine (e.g., activity of glycine oxidase for glycine, thermal stability of glycine oxidase, and substrate specificity of glycine oxidase for glycine,); and a method of analyzing glycine, that includes measuring glycine contained in a test sample using the modified enzyme; and the like. | 01-07-2016 |
20160000676 | COSMETIC COMPOSITION - The present invention provides a cosmetic composition containing (A) a powder composed of one or more kinds of the N-medium-chain-acyl basic amino acid powder represented by the following formula (I), (B) an inorganic powder, and (C) an oil material: | 01-07-2016 |
20150374666 | AQUEOUS LIQUID COMPOSITION INCLUDING HIGH CONCENTRATION OF L-HISTIDINE - Aqueous liquid compositions containing histidine at a high concentration, which is preferable for oral ingestion, are useful for the production of foods, drinks, pharmaceutical products, and the like. Particular aqueous liquid compositions contain histidine at a concentration greater than 20 wt % and may further contain a divalent or higher valent organic acid. | 12-31-2015 |
20150368518 | PROTECTIVE FILM-LAMINATED ADHESIVE SHEET - Protective film-laminated adhesive sheets which include; an adhesive sheet including a support having first and second surfaces and a resin composition layer in contact with the second surface of the support; and a protective film having first and second surfaces with the second surface of the protective film in contact with the resin composition layer of the adhesive sheet and in which the first surface of the protective film has an arithmetic mean roughness (Ra | 12-24-2015 |
20150368242 | NOVEL TETRAHYDROPYRIDOPYRIMIDINONE DERIVATIVE - An object is to provide a novel compound having a higher MGAT2 inhibitory activity than conventional compounds. A compound represented by the following general formula (I) or a pharmaceutically acceptable salt thereof is provided. | 12-24-2015 |
20150361133 | METHOD FOR PRODUCING GAMMA -GLUTAMYL-VALYL-GLYCINE CRYSTAL - The present invention provides a method for efficiently producing a γ-glutamyl-valyl-glycine crystal. Specifically, the present invention provides a method for producing a γ-glutamyl-valyl-glycine crystal, which includes the steps of: preparing a mixed solution of valyl-glycine or a salt thereof and γ-glutamyl-valyl-glycine, wherein the mixed solution contains valyl-glycine or the salt thereof in an amount of 20 mass % or more relative to the mass of γ-glutamyl-valyl-glycine; adjusting the amount of valyl-glycine or the salt thereof in the prepared mixed solution to 0.1 mass % or more and less than 20 mass % relative to the mass of γ-glutamyl-valyl-glycine to prepare a γ-glutamyl-valyl-glycine solution; and subjecting the γ-glutamyl-valyl-glycine solution to a crystallization procedure to produce the γ-glutamyl-valyl-glycine crystal. | 12-17-2015 |
20150359252 | Nutrition Composition - The present invention provides a food intake regulating agent which improves anorexia and overeating and is safe for ingestion for a long term. The present invention relates to a food intake regulating agent containing 3 kinds of amino acids: threonine, methionine and tryptophan, as active ingredients. | 12-17-2015 |
20150344405 | Method for Preserving 1,5-Pentanediamine or Salt Thereof, Method for Preventing Discoloration of 1,5-Pentanediamine or Salt Thereof, and 1,5-Pentanediamine or Salt Thereof in Container - Means of preserving 1,5-pentanediamine or a salt thereof without deterioration is provided. 1,5-pentanediamine or a salt thereof is preserved by adjusting any of a water content of 1,5-pentanediamine or a salt thereof purified through a distillation process, a temperature condition, and a material that comes into contact with 1,5-pentanediamine or a salt thereof. | 12-03-2015 |
20150343096 | LIQUID PREPARATION FOR ORAL ADMINISTRATION FOR USE IN CT COLONOGRAPHY, AND COMPOSITION FOR IMAGING DIGESTIVE TRACT - There are provided a liquid preparation for oral administration which contains barium that is likely to be mixed with residues and is less likely to be precipitated in the intestinal tract, and a liquid preparation for oral administration and a composition for imaging a digestive tract which contain barium and enable the reduction of the dose of an intestinal tract cleaning solution in a the intestinal tract pretreatment. That is, there are provided an orally administered liquid preparation which contains barium and one or more types of thickening agents selected from the group consisting of a natural polysaccharide and a cellulose-based polymer, in which the viscosity at a shear rate of 21.54 s | 12-03-2015 |
20150337254 | APPARATUS FOR CONTROLLING AMMONIA AND A METHOD FOR CONTROLLING AMMONIA - An method for controlling ammonia concentration of a culture medium contained in a culture tank, by using an ammonia-controlling apparatus comprising at least an ammonia feeder that supplies ammonia to the culture tank, an ammonia sensor that responds to non-ionized ammonia in the culture medium contained in the culture tank, and a control part connected to the ammonia feeder and the ammonia sensor, and which method comprises the following steps performed by the control part: calculating non-ionized ammonia concentration of the culture medium contained in the culture tank from the signal from the ammonia sensor by using a calibration curve representing relation between non-ionized ammonia concentration of the culture medium contained in the culture tank and a signal from the ammonia sensor; and directing the ammonia feeder to supply ammonia to the culture tank when the calculated non-ionized ammonia concentration is lower than a predetermined concentration. | 11-26-2015 |
20150329832 | CULTURE METHOD FOR STABLE PROLIFERATION OF PLURIPOTENT STEM CELL WHILE MAINTAINING UNDIFFERENTIATED STATE - Cultivating a pluripotent stem cell in a medium comprising at least one member selected from the group consisting of ethanolamine, an ethanolamine analog, and a pharmaceutically acceptable salt thereof, and which is substantially free of β-mercaptoethanol or contains β-mercaptoethanol at a concentration of not more than 9 μM, and the like, is effective for the proliferation of a pluripotent stem cell while maintaining an undifferentiated state. | 11-19-2015 |
20150320712 | Nutritional Composition for Gastrostomy-Tube Patients - A nutritional composition for gastrostomy-tube patients who are at an increased development risk of aspiration pneumonia and require careful risk management, which can be more safely consumed by gastrostomy-tube patients while suppressing the development of aspiration pneumonia, is administered to those patients who require risk management for aspiration pneumonia, and contains a protein source, a carbohydrate source, and a lipid source, the protein source including only amino acids. | 11-12-2015 |
20150313889 | HETEROARYLCARBOXYLIC ACID ESTER DERIVATIVE - Compounds represented by formula (I): | 11-05-2015 |
20150311012 | MEMBRANE SWITCH AND OBJECT EMPLOYING SAME - A membrane switch in which a first conductive part is formed on a first substrate, a second conductive part is formed on a second substrate, and the substrates are layered via a spacer such that the conductive parts face each other with a space therebetween, and an organic material showing piezoelectricity is filled, or disposed in the space such that an air gap is present, are useful for obtaining an output signal corresponding to an applied pressure. | 10-29-2015 |
20150307907 | Method for Producing L-Amino Acid - A method for producing an L-amino acid is provided. An L-amino acid is produced by culturing a coryneform bacterium having an L-amino acid-producing ability, which is modified so that the activity of a phosphate transporter is increased, in a medium, and collecting the L-amino acid from the medium. | 10-29-2015 |
20150290108 | COSMETIC COMPOSITION - The problem of the present invention is to provide a protein hydrophilicity-increasing agent capable of effectively increasing water permeability of (swelling) hair, skin and the like while suppressing damages on the hair, skin and the like constituted of the protein. | 10-15-2015 |
20150284375 | HETEROCYCLIC AMIDE DERIVATIVE AND MEDICINE CONTAINING SAME - Compound represented by formula (I): | 10-08-2015 |
20150276710 | Sweet Taste Receptor Chimeric Proteins and Use Thereof - A sweet taste substance or a sweet taste-regulating substance is detected by contacting a test substance with a cell that expresses a chimeric protein of human T1R2 and mouse T1R2, and/or a chimeric protein of human T1R3 and mouse T1R3, and may further express a G protein α subunit, and by detecting an interaction between the chimeric proteins and the test substance. | 10-01-2015 |
20150275246 | Method for Producing L-Amino Acid - A method for producing of an L-amino acid is provided. An L-amino acid is produced by culturing a bacterium belonging to the family Enterobacteriaceae and having an L-amino acid-producing ability, which has been modified so that the acpP-fabF operon is attenuated, in a medium, and collecting the L-amino acid from the medium or cells of the bacterium. | 10-01-2015 |
20150275233 | METHOD OF PRODUCING ISOPRENE MONOMER - A host cell includes a heterogeneous expression unit including: (a) a polynucleotide encoding a mevalonate kinase derived from a microorganism belonging to a genus selected from | 10-01-2015 |
20150272174 | METHOD OF PRODUCING STARCH-CONTAINING FOOD AND ENZYME PREPARATION FOR MODIFYING STARCH-CONTAINING FOOD - Starch-containing foods having improved physical properties and taste may be obtained by adding a branching enzyme and an α-glucosidase. | 10-01-2015 |
20150259717 | Method for Producing an Acidic Substance Having a Carboxyl Group - An acidic substance having a carboxyl group is produced by culturing in a medium a microorganism which has been modified to enhance expression of the ybjL gene, and collecting the acidic substance having a carboxyl group from the medium. | 09-17-2015 |
20150259716 | Method for Producing Basic Substance - A method for producing a basic substance by fermentation comprising culturing a microorganism having an ability to produce the basic substance in a liquid medium contained in a fermentation tank to produce and accumulate the basic substance in the medium, wherein amount of sulfate and/or chloride ions used as counter ions of the basic substance is reduced by adjusting total ammonia concentration in the medium to be within a specific concentration range during at least a part of the total period of culture process. | 09-17-2015 |
20150254411 | METHOD OF EVALUATING PANCREATIC CANCER, PANCREATIC CANCER-EVALUATING APPARATUS, PANCREATIC CANCER-EVALUATING METHOD, PANCREATIC CANCER-EVALUATING PROGRAM PRODUCT, PANCREATIC CANCER-EVALUATING SYSTEM, AND INFORMATION COMMUNICATION TERMINAL APPARATUS - A method of evaluating pancreatic cancer includes (I) an obtaining step of obtaining amino acid concentration data on a concentration value of an amino acid in blood collected from a subject to be evaluated, and (II) an evaluating step of evaluating a state of pancreatic cancer in the subject by calculating a value of a formula using the amino acid concentration data of the subject obtained at the obtaining step and the formula previously established for evaluating the state of pancreatic cancer, including an explanatory variable to be substituted with the concentration value of the amino acid. The amino acid concentration data includes the concentration values of at least two amino acids of Asn, His, Thr, Ala, Cit, Arg, Tyr, Val, Met, Lys, Trp, Gly, Pro, Orn, Ile, Leu, Phe, Ser, and Gln, and the formula includes at least two explanatory variables to be substituted with the concentration values of at least two amino acids of Asn, His, Thr, Ala, Cit, Arg, Tyr, Val, Met, Lys, Trp, Gly, Pro, Orn, Ile, Leu, Phe, Ser, and Gln. | 09-10-2015 |
20150250052 | METHOD FOR PRODUCING PRINTED WIRING BOARD - Printed wiring boards, in which the insulating layer exhibits excellent peel strength with respect to a conductive layer after a roughening treatment, even when using a resin composition having a high content of inorganic filler, may be obtained by: (A) laminating, onto an internal layer substrate, an adhesive sheet which includes a support and a resin composition layer in contact with the support, so that the resin composition layer is in contact with the internal layer substrate; (B) thermally curing the resin composition layer to form an insulating layer; and (C) removing the support, when the support satisfies certain conditions (TD1) and (TD2) in a TD direction thereof when it is heated under specific heating conditions. | 09-03-2015 |
20150218605 | Method for Producing L-Amino Acid - A method for producing an L-amino acid using a fatty acid as the carbon source is provided. An L-amino acid is produced by culturing a | 08-06-2015 |
20150211033 | Method for Producing L-Amino Acid - A method for producing an L-amino acid using linoleic acid as the carbon source is provided. An L-amino acid is produced by culturing a bacterium belonging to the family Enterobacteriaceae and having an L-amino acid-producing ability, which has been modified so that the 2,4-dienoyl-CoA reductase activity is increased, in a medium containing linoleic acid, and collecting the L-amino acid from the medium. | 07-30-2015 |
20150203881 | Method for Producing an L-Amino Acid Using a Bacterium of the Enterobacteriaceae Family - A method for producing an L-amino acid is described, for example L-threonine, L-lysine, L-histidine, L-phenylalanine, L-arginine, L-tryptophan, or L-glutamic acid, using a bacterium of the Enterobacteriaceae family, wherein the bacterium has been modified to enhance an activity of a wild-type alcohol dehydrogenase encoded by the adhE gene or a mutant alcohol dehydrogenase which is resistant to aerobic inactivation. | 07-23-2015 |
20150197782 | DNA ENCODING DIPEPTIDE-SYNTHESIZING ENZYME (VARIANTS), BACTERIUM BELONGING TO THE GENUS ESCHERICHIA, AND METHODS FOR PRODUCING DIPEPTIDES USING THEREOF - The present invention describes novel bacterial L-amino acids α-ligases, which catalyzing reaction of dipeptide formation having an acidic L-amino acid such as L-Asp or L-Glu at the N-terminus. The method for producing dipeptides using said L-amino acids α-ligases and a bacterium of the family Enterobacteriaceae, particularly a bacterium belonging to the genus | 07-16-2015 |
20150190328 | LIQUID CLEANSER COMPRISING STEROL ESTER - Provided is a composition containing a sterol ester, which is an oil poorly soluble in water, and superior in transparency, stability, foaming property, rinsability, skin feel (during rinsing and/or after use), and emollience. A composition containing
| 07-09-2015 |
20150190325 | CLEANSING AGENT COMPOSITION COMPRISING SULFONATE-TYPE SURFACTANT AND/OR SULFATE-TYPE ANIONIC SURFACTANT AND HETEROCYCLIC COMPOUND - A cleansing agent composition containing
| 07-09-2015 |
20150183725 | METHOD OF PRODUCING BASIC AMINO ACID OR BASIC AMINO ACID SALT - [Problem] It is to provide a method of producing basic amino acid or basic amino acid salt suitable for each use for medicine, industrial use, feed, food additive and the like, by a simple method to remove HCl from HCl salt of basic amino acid efficiently. | 07-02-2015 |
20150181920 | METHOD FOR PRODUCING PROCESSED AQUATIC FOOD AND ENZYME PREPARATION FOR MODIFYING PROPERTY OF PROCESSED AQUATIC FOOD - By using a glucose oxidase and a metal-containing yeast, a processed aquatic food of which physical property is improved, and an enzyme preparation for modifying a property of a processed aquatic food can be obtained. | 07-02-2015 |
20150181898 | FROZEN HEATED GYOZA AND MANUFACTURING METHOD THEREOF - A frozen heated gyoza dumpling easy to cook by heating after freeze preservation and superior in the texture can be obtained by attaching a batter liquid containing 70-90 wt % of water to at least a surface to be baked of the gyoza dumpling at a proportion of 18-30 parts by weight per 100 parts by weight of the gyoza dumpling. In addition, a manufacturing method thereof is provided. | 07-02-2015 |
20150175954 | Method for Producing a Nutrient Additive Using a Microalga - A medium component for more efficiently culturing a microorganism or microalga is provided. A nutrient additive useful in culturing a microorganism or microalga is produced by culturing a microalga in a medium to produce biomass derived from the microalga in the medium, adding an acid to the biomass to hydrolyze the biomass, and preparing the hydrolysate of the biomass as a nutrient additive. | 06-25-2015 |
20150159215 | Method for Determining Nutritional Requirements of Industrial Animal - A means for determining the nutritional requirements of an industrial animal is provided. The objects can be achieved by identifying an mRNA the expression of which changes before and/or after a change in physiological condition in an industrial animal by comparing mRNA expression data obtained before and after the change in physiological condition, identifying a metabolic pathway of which the expression changes before and after the change in the physiological condition on the basis of the identified mRNA, and identifying a metabolite that is highly required by the industrial animal before or after the change in physiological condition on the basis of the identified metabolic pathway. | 06-11-2015 |
20150133567 | COMPOSITION CONTAINING GLYCEROL AND GLYCINE - The present invention aims to provide a production method of a composition containing (A) glycerol and (B) glycine, which includes using glycerol substantially free of dihydroxyacetone or having a dihydroxyacetone content of not more than 150 ppm. According to the present invention, a composition, particularly a cosmetic composition, having a moist feeling but free of stickiness and showing suppressed coloration can be provided. | 05-14-2015 |
20150111859 | Moisturizer and Cosmetic Agent Containing Same - Provided is a moisturizer having hygroscopicity and water retention ability, and also provided is a composition superior in antiseptic property and feeling on application, in addition to moisturizing property, and free of coloration and odorization. | 04-23-2015 |
20150104517 | AMINO-ACID-CONTAINING MEDICINAL GRANULAR PREPARATION HIGHLY EASY TO TAKE - The present invention aims to provide an amino acid-containing granule preparation improved in the ease of taking medication than conventional products, which disintegrates rapidly. The amino acid-containing granule preparation of the present invention containing granules having a maximum particle size of substantially not more than 1000 μm and a bulk density of not less than 0.57 g/mL markedly improves ease of taking medication without impairing disintegration property, as compared to conventional amino acid-containing granule preparations. | 04-16-2015 |
20150099733 | HETEROARYLCARBOXYLIC ACID ESTER DERIVATIVE - Compounds represented by the following formula (I); | 04-09-2015 |
20150080565 | OLIGONUCLEOTIDE WITH PROTECTED BASE - The present invention provides a protected nucleotide for elongation, which can be purified efficiently and in a high yield by a liquid-liquid extraction operation, and can achieve an oligonucleotide production method by a phosphoramidite method. | 03-19-2015 |
20150079644 | Method for Producing 3-Acetylamino-4-Hydroxybenzoic Acid - The present invention provides a method for conveniently and efficiently producing a 3-acetylamino-4-hydroxybenzoic acid-type compound that is a stable compound by a process using a microorganism. Specifically the present invention provides a microorganism having an ability to produce 3-amino-4-hydroxybenzoic acid, that is modified so as to increase an activity to form 3-amino-4-hydroxybenzoic acid from dihydroxyacetone phosphate and aspartate semialdehyde, wherein the microorganism is modified so as to increase an N-hydroxyarylamine O-acetyltransferase (NhoA) activity, as well as a method for producing the 3-acetylamino-4-hydroxybenzoic acid-type compound using such a microorganism. | 03-19-2015 |
20150079209 | DIABETES-INDUCIBLE BACTERIUM - The present invention provides a diabetes-inducing bacterium and use thereof, and a reagent and a detection method for detecting the bacterium. According to the present invention, enteric colonization of the diabetes-inducing bacterium can be prevented, and diabetes can be treated and/or prevented. | 03-19-2015 |
20150017693 | Auto-Indicible Expression System, and the Use Thereof for Producing Useful Metabolites Using a Bacterium of the Family Enterobacteriaceae - The present invention describes a method for producing a useful metabolite using a bacterium of the family Enterobacteriaceae, particularly a bacterium belonging to the genus | 01-15-2015 |
20150017306 | EMULSIFIED DISPERSANT AND EMULSIFIED COMPOSITION - Emulsifying dispersants, comprising an amphipathic substance and an electrolyte, wherein the amphipathic substance forms two or more layers, are capable of stably dispersing a large amount of oil even when used in a small amount. Emulsion compositions containing such an emulsifying dispersant show high emulsion stability even when added to a food or drink containing an electrolyte, and can be used to prepare a final product without the need for a complicated operation. | 01-15-2015 |
20150011511 | HETEROARYLCARBOXYLIC ACID ESTER DERIVATIVE - Compounds represented by formula (I): | 01-08-2015 |
20150011003 | CULTURE MEDIUM FOR PROLIFERATING STEM CELL, WHICH CONTAINS SULFATED COMPOUND - A medium which comprises a fibroblast growth factor (FGF), and a sulfated compound or a pharmaceutically acceptable salt thereof at a concentration which promotes the growth of a stem cell in the presence of FGF, is useful for culturing stem cells. | 01-08-2015 |
20150010963 | Method for Producing Basic Substance - A method for producing a basic substance by fermentation comprising culturing a microorganism having an ability to produce the basic substance in a liquid medium contained in a fermentation tank to produce and accumulate the basic substance in the medium, wherein amount of sulfate and/or chloride ions used as counter ions of the basic substance is reduced by adjusting total ammonia concentration in the medium to be within a specific concentration range during at least a part of the total period of culture process. | 01-08-2015 |
20150010962 | Method for Producing Basic Substance - A method for producing a basic substance by fermentation comprising culturing a microorganism having an ability to produce the basic substance in a liquid medium contained in a fermentation tank to produce and accumulate the basic substance in the medium, wherein amount of sulfate and/or chloride ions used as counter ions of the basic substance is reduced by adjusting total ammonia concentration in the medium to be within a specific concentration range during at least a part of the total period of culture process. | 01-08-2015 |
20150010936 | Modified Leucine Dehydrogenase - The present invention provides a means and method useful for measurement of a total branched-chain amino acid concentration. Specifically, the present invention provides a modified enzyme in which at least one amino acid residue is mutated so as to improve a property of a leucine dehydrogenase which is associated with the measurement of the total branched-chain amino acids, such as, for example, substrate specificities of leucine dehydrogenase for total branched-chain amino acids, activity of leucine dehydrogenase for any branched-chain amino acids, and thermal stability of leucine dehydrogenase; and a method of analyzing the total branched-chain amino acids, comprising measuring the total branched-chain amino acids contained in a test sample using the modified enzyme. | 01-08-2015 |
20150010689 | PROCESS FOR PRODUCING MATERIAL FOR FOOD OR BEVERAGE - Heating an oil from a plant or animal while supplying oxygen at a dissolved oxygen supply speed of not less than 0.058 mg/L/min to the oil from plant or animal is a convenient production method of a material for food or drink, which is capable of imparting an aroma and/or a flavor, which are/is mellow and rich in variety, to a food or drink. | 01-08-2015 |
20150010489 | COSMETIC COMPOSITION - Provided is a composition that masks the odor characteristic of anisic acid or phenylalkanol, is superior in appearance and texture on application, and provides moist feeling to the skin after application. Specifically, a composition containing (A) acyl proline represented by the formula (I) or a salt thereof, and (B) one or more kinds selected from anisic acid and phenylalkanol is provided. | 01-08-2015 |
20140371424 | BENZYLIC COMPOUND - The present invention provides a protecting reagent that can be removed in a high yield even under acidic conditions and can afford a resulting product at a high purity in an organic synthesis reaction such as peptide synthesis and the like. The inventive protecting reagent is particular benzylic compound having only one hydroxyl group substituted by an organic group having an aliphatic hydrocarbon group having a carbon number of not less than 14. | 12-18-2014 |
20140368083 | PIEZOELECTRIC ELEMENT - Poly(α-amino acid) which contain: (A) a glutamic acid γ-ester unit represented by formula (I): and (B) one or more kinds of units selected from a glutamic acid γ-ester unit represented by formula (II), an alanine unit, a phenylalanine unit and an N | 12-18-2014 |
20140364579 | Escherichia coli Capable of Producing 3-Amino-4-Hydroxybenzoic Acid - The present invention provides a method for conveniently and inexpensively producing an amino-hydroxybenzoic acid-type compound such as 3-amino-4-hydroxybenzoic acid by utilizing | 12-11-2014 |
20140363857 | Method for Producing an L-Amino Acid - A method for producing an L-amino acid by preparing a processed product of a microalgae, which promotes production and accumulation of the L-amino acid by a bacterium having an ability to produce the L-amino acid, by culturing the microalgae in a medium, and processing the resulting culture at a midtemperature; culturing the bacterium in a medium containing the processed product of the microalgae to produce and accumulate the L-amino acid in culture; and collecting the L-amino acid from the culture. | 12-11-2014 |
20140357524 | Method for Quantifying Subject Substance - There is provided a method for quantifying a subject substance, of which typical examples are amino acids. The method of the present invention comprises the following steps: the step of allowing an enzyme that can generate pyrophosphate by using adenosine triphosphate (ATP) as a substrate with converting the subject substance to act on the subject substance to generate pyrophosphate; the step of allowing pyruvate pyrophosphate dikinase (PPDK) to act on the generated pyrophosphate in the presence of adenosine monophosphate (AMP) and phosphoenolpyruvate (PEP) to generate ATP, phosphoric acid, and pyruvate; and the step of quantifying the generated pyruvate, and amount of the subject substance is determined on the basis of the obtained amount of pyruvate. According to the present invention, an amino acid in a biological sample containing a lot of various kinds of contaminants such as inorganic phosphoric acid and urea can be conveniently and quickly quantified without being influenced by the contaminants. | 12-04-2014 |
20140350128 | BASIC AMINO ACID DERIVATIVE - Provided is a compound capable of gelling various aqueous compositions containing salt, acid and the like. | 11-27-2014 |
20140349371 | Protein Refolding Method - The present invention provides a method for producing a protein which has a restored native higher-order structure by bringing a protein which has lost its native higher-order structure into contact at pH 6.5 to 9.0 with a 1 to 3% aqueous solution of a specific surfactant, such as lauroylglutamic acid to obtain a solubilized solution of the protein; and then adding the solubilized solution to a buffer with pH 6.5 to 9.0 containing arginine or an arginine derivative at a concentration of 0.1 to 1.2 M to lower the concentration of the specific surfactant, such as lauroylglutamic acid, in the obtained mixture solution down to 0.02 to 0.275%. According to the present invention, it is possible to easily restore the native higher-order structure of a protein while smoothly removing the surfactant from the protein. | 11-27-2014 |
20140348767 | AMPHOTERIC ION-TYPE BASIC AMINO ACID DERIVATIVE - Provided is a compound capable of gelling various aqueous compositions containing salt, acid and the like. | 11-27-2014 |
20140343148 | PROPHYLACTIC OR THERAPEUTIC AGENT FOR IDIOPATHIC INFLAMMATORY MYOPATHIES - Administration of isoleucine, leucine and valine is effective for the prophylaxis and/or therapy of idiopathic inflammatory myopathy or idiopathic inflammatory myopathy associated with steroid-induced myopathy that develops during the course of treatment. This method is effective for the prophylaxis and/or therapy of idiopathic inflammatory myopathy or idiopathic inflammatory myopathy associated with steroid-induced myopathy that develops during the course of treatment. | 11-20-2014 |
20140341960 | GELLING AGENT - Provided is a gelling agent containing N-acyl acidic amino acid dialkylamide having a DL form ratio (D form/L form (weight/weight)) of 5/95-20/80 or 80/20-95/5, and using the gelling agent, a gel composition, particularly a rod-like gel composition, superior in transparency and strength, and superior in compatibility and spreadability when applied to the skin, hair and the like is provided. | 11-20-2014 |
20140336376 | PHARMACEUTICAL COMPOSITION FOR TREATING DIABETES - Provided is a compound represented by the following general formula (I), or a pharmaceutically acceptable salt thereof. This novel compound has a glycogen-synthase activation ability, but activates a receptor PPAR to a low degree and is highly safe. | 11-13-2014 |
20140335574 | Mutant Acetolactate Synthase and a Method for Producing Branched-Chain L-Amino Acids - A mutant bacterial acetolactate synthase (AHAS I) which is resistant to feedback inhibition by L-valine is described. Also described is a method for producing branched-chain L-amino acids using a bacterium from the Enterobacteriaceae family wherein the L-amino acid productivity of said bacterium is enhanced by the use of the acetolactate synthase (AHAS I) which is resistant to feedback inhibition by L-valine. This acetolactate synthase contains a mutant small subunit encoded by the mutant ilvN gene. | 11-13-2014 |
20140335553 | Novel L-Amino Acid Oxidase, Method for Measuring L-Lysin, Kit and Enzyme Sensor - Methods are provided measuring L-lysine using a variant enzyme, an L-lysine measurement kit, and an enzyme sensor. Variant L-amino acid oxidase having a predetermined amino acid mutation, and having oxidase activity that is highly substrate-specific for L-lysine; a method for measuring L-lysine using this variant enzyme; an L-lysine measurement kit; and an enzyme sensor are also provided. | 11-13-2014 |
20140329796 | HETEROCYCLIC AMIDE DERIVATIVE AND PHARMACEUTICAL PRODUCT CONTAINING SAME - The present invention aims to provide a novel compound having a TRPA1 antagonist activity, and a medicament containing the compound. Moreover, the present invention aims to provide a TRPA1 antagonist and a medicament useful for the prophylaxis or treatment of diseases involving TRPA1. | 11-06-2014 |
20140323669 | RESIN COMPOSITION FOR SEALING - Provided is a sealing resin composition simultaneously having good transparency, resistance to moisture permeability, and adhesiveness resistant to heat and humidity, and a sealing resin composition sheet obtained therefrom. | 10-30-2014 |
20140315261 | METHOD FOR PRODUCING AN L-AMINO ACID USING A BACTERIUM OF THE FAMILY ENTEROBACTERIACEAE HAVING ATTENUATED EXPRESSION OF THE yjjK GENE - The present invention provides a method for producing L-amino acids by fermentation using a bacterium of the family Enterobacteriaceae, particularly a bacterium belonging to the genus | 10-23-2014 |
20140309135 | REMEDY FOR DIABETES - A method of screening a compound having a hypoglycemic effect (hereinafter referred to as “hypoglycemic compound”), a remedy for diabetes which contains a compound having a novel function mechanism, etc. More specifically speaking, a method of screening a hypoglycemic compound capable of binding to the β subunit of a trimeric GTP-binding protein, a remedy for diabetes comprising a hypoglycemic compound, which is characterized by being capable of binding to the β subunit of a trimeric GTP-binding protein, as the active ingredient, etc. | 10-16-2014 |
20140308418 | FEED ADDITIVE COMPOSITION FOR RUMINANTS AND METHOD OF PRODUCING THE SAME - A food additive composition for ruminants of the dispersion type and a method of continuously producing the same. This food additive composition for ruminants, which contains 40% by weight or more but less than 65% by weight of a basic amino acid and has rumen bypass properties, is formulated into granules in an arbitrary shape which are scarcely classified when added to a silage or another feed. Thus, attempts have been made to develop a method of producing granules by which the milk yield of a lactation cow can be increased. Namely, it is intended to provide a food additive composition for ruminants which contains at least one protecting agent selected from among a hardened vegetable oil and a hardened animal oil having a melting point higher than 50° C. but lower than 90° C., 0.05 to 6% by weight of lecithin, water and 40% by weight or more but less than 65% by weight of a basic amino acid. It is also intended to provide a method of producing a food additive composition for ruminants characterized by comprising solidifying a molten mixture, which comprises at least one protecting agent selected from among a hardened vegetable oil and a hardened animal oil having a melting point higher than 50° C. but lower than 90° C., lecithin and a basic amino acid, by dipping in water. | 10-16-2014 |
20140308412 | FEED ADDITIVE COMPOSITION FOR RUMINANTS AND METHOD OF PRODUCING THE SAME - A feed additive composition includes a protective agent, lecithin in an amount of 0.05 to 6% by weight relative to a total weight of the composition, a basic amino acid in an amount of at least 40% by weight and less than 65% by weight relative to the total weight of the composition, and water. A method of producing a feed additive composition includes preparing a molten mixture of at least one protective agent, lecithin and at least one basic amino acid, and solidifying the molten mixture by immersing the molten mixture in water or an aqueous liquid. The protective agent includes hydrogenated vegetable oils and/or hydrogenated animal oils having melting points of greater than 50° C. and less than 90° C. | 10-16-2014 |
20140303122 | CASR AGONISTS - By searching various kinds of compounds having CaSR agonistic activity, the present invention provides CaSR agonistic agents, pharmaceutical compositions, preventive or therapeutic agents for diarrhea and kokumi-imparting agents each of which comprise the compound. More specifically, the present invention provides CaSR agonistic agents, pharmaceutical compositions, preventive or therapeutic agents for diarrhea and kokumi-imparting agents each of which comprise a glutamic acid derivative having CaSR agonistic activity or pharmaceutically acceptable salts thereof. | 10-09-2014 |
20140296483 | METHOD FOR REMOVING FMOC GROUP - The present invention relates to a method of removing an Fmoc group, including a step of mixing a compound represented by the formula (I): | 10-02-2014 |
20140295037 | METHOD, PROGRAM AND DEVICE FOR EVALUATING FOOD PREFERENCE OF PETS - A method, a program, and a device for evaluating food preference of pets that do not require humans to eat a pet food itself. The preference of pets can be evaluated by conducting sensory analysis on selected palatants contained in a pet food by humans. Accordingly, highly precise prediction of the preference can be made by a simple and intuitive method based on sensory attributes for human. Further, humans are not required to eat a pet food itself because the humans may conduct sensory analysis on selected palatants contained in the pet food. | 10-02-2014 |
20140287472 | Method for Producing L-Amino Acids Using Bacteriua of the Enterobacteriaceae Family - There is disclosed a method for producing L-amino acid, for example L-threonine, L-lysine, L-histidine, L-phenylalanine, L-arginine or L-glutamic acid, using a bacterium of the Enterobacteriaceae family, wherein the bacterium has been modified to enhance an activity of D-xylose permease. | 09-25-2014 |
20140275183 | AGENT FOR REDUCING SIDE EFFECTS OF KINASE INHIBITOR - The present invention relates to an agent for reducing the side effects of kinase inhibitors, the agent containing at least one branched-chain amino acid selected from among isoleucine, leucine and valine or a salt thereof as an active ingredient, and also relates to an anticancer medicine containing at least one branched-chain amino acid selected from among isoleucine, leucine and valine or a salt thereof, and a kinase inhibitor. | 09-18-2014 |
20140271510 | WHITENING COSMETIC - Provided is a cosmetic agent superior in a whitening effect (including prophylaxis and removal of pigmented spot) and having high safety. In addition, a superior melanin production suppressive agent is provided. | 09-18-2014 |
20140255996 | Method for Secretory Production of Protein - A method for secretory production of a heterologous protein is provided by developing a novel technique for improving ability of a coryneform bacterium to produce a heterologous protein by secretory production. By utilizing a coryneform bacterium having an ability to produce a heterologous protein by secretory production which has been modified so that the activity of a penicillin-binding protein is reduced and in which the activity of a cell surface layer protein has been reduced as an expression host, a heterologous protein is produced by secretory production. | 09-11-2014 |
20140255327 | NOVEL AMIDE DERIVATIVE AND WHITENING AGENT - Compound represented by formula (I): | 09-11-2014 |
20140246627 | ELECTROMAGNETIC WAVE ABSORPTION PLATE, AND COMPOSITION FORSAME AND METHOD FOR MANUFACTURING SAME - A plurality of kinds of carbonized powders obtained by carbonizing a plant material at different carbonization temperatures are dispersed in a resin to form a composition for an electromagnetic wave absorbing plate. When an electromagnetic wave absorbing plate is formed using the composition, the d/λ value in a non-reflective state of the electromagnetic wave absorbing plate can be adjusted to fall within the predetermined range rather than at a single point, by adjusting each weight ratio of the plural kinds of carbonized powders. | 09-04-2014 |
20140242643 | The Use of Phosphoketolase for Producing Useful Metabolites - The present invention provides a bacterium which has an ability to produce a useful metabolite derived from acetyl-coenzyme A, such as L-glutamic acid, L-glutamine, L-proline, L-arginine, L-leucine, L-cysteine, succinate, and polyhydroxybutyrate, wherein said bacterium is modified so that activities of D-xylulose-5-phosphate phosphoketolase and/or fructose-6-phosphate phosphoketolase are enhanced. The present invention also provides a method for producing the useful metabolite using the bacterium. | 08-28-2014 |
20140234916 | METHOD FOR PRODUCING MONATIN USING AN L-AMINO ACID AMINOTRANSFERASE - The present invention provides a methodology for improving a yield of 2R,4R-Monatin. Specifically, the present invention provides a method for producing 2S,4R-Monatin or a salt thereof, comprising contacting 4R-IHOG with an L-amino acid aminotransferase in the presence of an L-amino acid to form the 2S,4R-Monatin; a method for producing 2R,4R-Monatin or a salt thereof, comprising isomerizing the 2S,4R-Monatin to form the 2R,4R-Monatin; and the like. These production methods may further comprise condensing indole-3-pyruvate and pyruvate to form the 4R-IHOG, and deaminating a tryptophan to form the indole-3-pyruvate. | 08-21-2014 |
20140234901 | Method for Secretory Production of Protein - A novel technique for improving ability for secretory production of a multimeric protein of a coryneform bacterium is provided, and thereby a method for secretory production of a multimeric protein is provided. A multimeric protein is produced by secretory production utilizing a coryneform bacterium having an ability to produce a multimeric protein by secretory production and modified so that expression of a gene coding for a metallopeptidase is increased as an expression host. | 08-21-2014 |
20140220637 | Method for Secretory Production of Protein - A novel technique for improving secretory production of a heterologous protein by coryneform bacteria is described, and thereby a method for secretory production of a heterologous protein is provided. A coryneform bacterium is cultured so that it secretes a heterologous protein, the bacterium having a genetic construct which includes a promoter sequence that functions in the coryneform bacterium, a nucleic acid sequence coding for a signal peptide that functions in the coryneform bacterium, which is ligated downstream from the promoter sequence, and a nucleic acid sequence coding for a fusion protein having an amino acid sequence that includes Gln-Glu-Thr and the heterologous protein, which is ligated downstream from the nucleic acid sequence coding for the signal peptide. | 08-07-2014 |
20140219993 | PLANT VIRUS INFECTION INHIBITOR AND A METHOD FOR INHIBITING PLANT VIRUS INFECTION USING THE SAME - A virus infection inhibitor containing a fermentation by-product such as an amino acid fermentation by-product and a nucleic acid fermentation by-product is sprinkled onto a plant body of a plant, such as tobacco, tomato, bell pepper, and chili pepper to control a disease induced by infection of a virus such as Tobamovirus viruses and Cucumovirus viruses. | 08-07-2014 |
20140213761 | DIPHENYLMETHANE COMPOUND - The present invention aims to provide a compound superior in broad utility and stability, which is useful as a protecting reagent (anchor) of amino acid and/or peptide in liquid phase synthesis and the like of a peptide having a C-terminal etc., which are of a carboxamide (—CONHR)-type, an organic synthesis reaction method (particularly peptide liquid phase synthesis method) using the compound, and a kit for peptide liquid phase synthesis containing the compound, and has found that the object can be achieved by a particular compound having a diphenylmethane skeleton. | 07-31-2014 |
20140212920 | MUTANT GAMMA-GLUTAMYLTRANSFERASE, AND A METHOD FOR PRODUCING GAMMA-GLUTAMYLVALYLGLYCINE OR A SALT THEREOF - A method for producing γ-Glu-Val-Gly comprising the step of reacting Val-Gly with a γ-glutamyl group donor in the presence of a γ-glutamyltransferase, a microorganism containing the enzyme, or a processed product thereof to generate γ-Glu-Val-Gly, wherein the γ-glutamyltransferase consists of a large subunit and a small subunit, and the small subunit has a specific mutation. | 07-31-2014 |
20140206705 | CRYSTALS OF SALTS OF PHENYLALANINE DERIVATIVES - Provided is a crystal of a salt of the compound represented by formula (I), which is excellent in its solubility in water. In particular, also provided is a crystal of hydrochloride, hydrobromate, sulfate, nitrate, p-toluenesulfonate or methanesulfonate of the compound represented by formula (I). | 07-24-2014 |
20140197106 | DIALYSIS PREPARATION - The present invention provides a pharmaceutical composition for dialysis wherein the decline of ionized calcium concentration in an acetate-free bicarbonate dialysate comprising no acetic acid and/or sodium acetate is controlled. The present invention further provides a dialysis agent A that comprises electrolytes, citric acid and/or citrate as pH adjuster, and/or glucose, for preparation of bicarbonate dialysate; the agent A characterized by being adjusted by citric acid and/or citrate so as to keep the electrolyte ionized calcium concentration not less than 1 mmol/L in a prepared bicarbonate dialysate. In a specific aspect of the present invention, sodium citrate is used as citrate, and the present invention provides a dialysate obtained from above. | 07-17-2014 |
20140162325 | Method for Producing an L-Amino Acid Using a Bacterium of the Family Enterobacteriaceae Having Enhanced Expression of the Flagella Formation and Motility Cascade Genes - The present invention provides a method for producing L-amino acid using a bacterium belonging to the family Enterobacteriaceae, particularly a motile bacterium belonging to the genus | 06-12-2014 |
20140155448 | AMINO-ACID-CONTAINING COMPOSITION FOR ENHANCING RECOVERY FROM MUSCLE FATIGUE - Administering an amino acid-containing composition, containing the following amino acids (1)-(9), wherein
| 06-05-2014 |
20140150855 | POROUS STRUCTURE BODY AND METHOD FOR PRODUCING THE SAME - A functional material having excellent photocatalytic activity, electric characteristics and the like is provided. A porous structure body | 06-05-2014 |
20140147909 | Method for Producing an L-Amino Acid Using a Bacterium of the Enterobacteriaceae Family - The present invention provides a method for producing an L-amino acid from ethanol using a bacterium of the | 05-29-2014 |
20140138654 | POLY ALPHA-AMINO ACID AND FERROELECTRIC MEMORY ELEMENT USING SAME - Ferroelectric memory elements which contain a poly α-amino acid which is a copolymer containing a glutamic acid-γ-ester unit represented by the formula (I), defined herein, and a glutamic acid-γ-ester unit represented by the formula (II), defined herein, in a molar ratio of units of formula (I) to units of formula (II) of 10/90-90/10 are useful as recording elements such as RFID and the like. | 05-22-2014 |
20140127819 | METHOD OF EVALUATING NASH, NASH-EVALUATING APPARATUS, NASH-EVALUATING METHOD, NASH-EVALUATING PRODUCT, NASH-EVALUATING SYSTEM, INFORMATION COMMUNICATION TERMINAL APPARATUS, METHOD OF SEARCHING FOR PREVENTING/AMELIORATING SUBSTANCE FOR NASH - A method of evaluating NASH includes (I) an obtaining step of obtaining amino acid concentration data on a concentration value of an amino acid in blood collected from a subject to be evaluated and (II) a concentration value criterion evaluating step of evaluating a state of a hepatic fibrogenesis in a NASH in the subject, based on the amino acid concentration data of the subject obtained at the obtaining step. | 05-08-2014 |
20140127761 | Method for Producing Fatty Acid - A method for producing a fatty acid, which comprises adding an organic solvent to a culture of an alga obtained by culturing the alga in a culture medium, and stirring the culture medium to allow a transesterification or hydrolysis reaction of a lipid, and collecting a fatty acid ester or a fatty acid from the reaction mixture. | 05-08-2014 |
20140126843 | STANDING BAG TYPE INFUSION LIQUID CONTAINER - The present invention relates to a standing bag type container and aims to increase a visibility of the residual liquid volume in accordance with the progress of infusion process. The standing bag type container includes a bag | 05-08-2014 |
20140120233 | Method for Producing Lanthionine Derivative - The present invention relates to a method for producing a novel lanthionine derivative having a CaSR agonist activity, an intermediate compound of the lanthionine derivative, and use of the intermediate compound for production of a CaSR agonist, a kokumi-imparting agent, and a food and/or beverage ingredient. | 05-01-2014 |
20140118964 | METHOD FOR PRODUCING PRINTED WIRING BOARD - A method for producing a printed wiring board which is capable of forming an insulating layer having a surface with low roughness and high adhesion strength to a conductive layer and of achieving an excellent performance in removal of smear, involves the following steps (A) to (F) in this order: (A) laminating, onto an internal layer circuit substrate, a resin sheet with a support which includes a support and a resin composition layer in contact with the support so that the resin composition layer is in contact with the internal layer circuit substrate; (B) thermally curing the resin composition layer of the resin sheet with a support to form an insulating layer; (C) perforating the insulating layer to form a via hole; (D) performing a desmear treatment; (E) peeling the support; and (F) forming a conductive layer on a surface of the insulating layer. | 05-01-2014 |
20140113378 | Method of evaluating fatty liver related disease, fatty liver related disease-evaluating apparatus, fatty liver related disease-evaluating method, fatty liver related disease-evaluating program product, fatty liver related disease-evaluating system, information communication terminal apparatus, and method of searching for prophylactic/ameliorating substance for fatty liver related disease - A method of evaluating fatty liver related disease includes (I) an obtaining step of obtaining amino acid concentration data on a concentration value of an amino acid in blood collected from a subject to be evaluated and (II) a concentration value criterion evaluating step of evaluating a state of a fatty liver related disease including at least one of fatty liver, NAFLD, and NASH in the subject, based on the amino acid concentration data of the subject obtained at the obtaining step. | 04-24-2014 |
20140113344 | ISOPRENE SYNTHASE AND GENE ENCODING THE SAME, AND METHOD FOR PRODUCING ISOPRENE MONOMER - The present invention provides means useful for establishing an excellent isoprene monomer production system. Specifically, the present invention provides a polynucleotide of the following (a), (b), or (c):
| 04-24-2014 |
20140107207 | Method for Inactivating Viruses With Slightly Acidic Arginine - The present invention provides a method for conveniently producing a protein formulation in which viruses are inactivated, without impairing the quality of the obtained protein formulation, characterized by including the step of exposing the protein formulation contaminated with the viruses to a 0.1-2M aqueous solution of arginine, an arginine derivative, or a mixture thereof, the aqueous solution being adjusted to pH 3.5 to 5. The present invention also provides a virus inactivation method characterized by including the step of contacting a virus-containing object with a 0.1-2M aqueous solution of arginine, an arginine derivative, or a mixture thereof, the aqueous solution being adjusted to pH 3.5 to 5. | 04-17-2014 |
20140102623 | RESIN COMPOSITION FOR INSULATING LAYER FOR MULTI-LAYERED PRINTED BOARD - Epoxy resin compositions, which comprise (A) en epoxy resin having two or more epoxy groups in a molecule; (B) a phenol type curing agent where an average hydroxyl group content in a molecule (a mean value of (the total number of hydroxyl groups)/(the total number of benzene rings)), P, satisfies the equation 0 | 04-17-2014 |
20140099672 | Method for Preparing Polymeric Protein Composed of Monomeric Protein Produced by Fusing Protein Having Immunoglobulin Fold Structure to Protein Capable of Serving as Subunit Structure - The present invention provides a method for producing a multimeric protein composed of a monomeric protein, wherein the monomeric protein is obtained by fusing a protein having an immunoglobulin fold structure to a protein that can serve as a subunit structure, the method including the steps of:
| 04-10-2014 |
20140094489 | HETEROCYCLIC CARBOXYLIC ACID ESTER DERIVATIVE - The present invention provides a blood glucose elevation inhibitor having a serine protease inhibitory action, which is a novel therapeutic or prophylactic agent for obesity. A compound represented by the following formula (I) | 04-03-2014 |
20140094434 | AMINO ACID COMPOSITION - Amino acid compositions containing a carbohydrate and any one or more kinds of alanine, proline and glycine as amino acid can suppress a rapid increase in the blood glucose level immediately after ingestion and a decrease in the blood glucose level due to prolonged exercise, and can improve exercise performance. In addition, the present invention provides inhibitors of an increase in the blood glucose level immediately after carbohydrate ingestion, an inhibitor of a decrease in the blood glucose level due to a prolonged exercise, and an exercise performance improver. Therefore, the present invention provides an energy supplement useful for those who exercise (particularly prolonged exercise). | 04-03-2014 |
20140088291 | METHOD FOR PRODUCING PEPTIDE - The present invention provides a production method of peptide, which includes the following step (1).
| 03-27-2014 |
20140087152 | RESIN COMPOSITION - Resin compositions which contain an epoxy resin, an alkoxy oligomer, and an inorganic filler provide insulating layers that have a surface with not only low arithmetic mean roughness but also low root mean square roughness in a wet roughening step and that are capable of forming thereon a plated conductive layer having a sufficient peel strength that can be formed while maintaining the glass transition temperature and thermal expansion coefficient. | 03-27-2014 |
20140080999 | METHOD FOR PRODUCING PEPTIDE - The present invention provides a production method of a protected amino acid, protected peptide or peptide, including precipitation and solid-liquid separation of C-protected amino acid or C-protected peptide in a solvent containing water-containing acetonitrile, after removing the N-terminal protecting group from N-protected C-protected amino acid or N-protected C-protected peptide wherein the C-terminal carboxy group is protected by an anchor group. | 03-20-2014 |
20140080790 | HETEROARYLCARBOXYLIC ACID ESTER DERIVATIVE - Compounds represented by formula (I): | 03-20-2014 |
20140080185 | Method for Producing a Target Substance by Fermentation - A method is described for producing a target substance utilizing a microorganism by culturing the microorganism in a medium to produce and accumulate the target substance in the medium, and then collecting the target substance from culture. The microorganism is imparted with isomaltase activity, or modified to increase isomaltase activity. | 03-20-2014 |
20140065260 | FEED ADDITIVE COMPOSITION FOR RUMINANTS CONTAINING ACIDIC OR NEUTRAL AMINO ACID, AND METHOD FOR PRODUCTION THEREOF - A feed additive composition includes a protective agent, lecithin, an acidic or neutral amino acid, and water. A method of producing a feed additive composition includes preparing a molten mixture of a protective agent, lecithin, and an acidic or neutral amino acid, and immersing the molten mixture in water or an aqueous liquid to obtain a solidified mixture. Feed additives may be obtained by such method. The protective agent may include a hydrogenated vegetable oil or hydrogenated animal oil having a melting point of higher than 50° C. and lower than 90° C. | 03-06-2014 |
20140065186 | Immunostimulant for Animals, Feed Containing the Same, and Method for Producing the Same - By administering sterilized bacterial cells obtained by heat treating cells of a coryneform bacterium or an enterobacterium under a condition of pH 2 to 5 at 90 to 120° C. for 3 minutes to 4 hours, or a feed containing such sterilized bacterial cells to a mammal, fowl, fish, or crustacean, immunity of these animals is enhanced. | 03-06-2014 |
20140051772 | CLEANING AGENT COMPOSITION - The problem of the present invention is provision of a cleansing composition providing good amount and good quality of lather. Using a particular alkenoic acid or a salt thereof, the above-mentioned problem can be solved. In addition, the cleansing composition provided by the present invention is stable in various formulations and also useful for rough skin and damaged hair. | 02-20-2014 |
20140051651 | LIQUID CLEANSING COMPOSITION - The present invention aims to provide a liquid cleansing composition showing a good amount of lather and superior in a moist feeling after washing. | 02-20-2014 |
20140051132 | Method for Producing an L-Amino Acid Belonging to the Glutamate Family, Using a Coryneform Bacterium - The present invention provides a method for producing an L-amino acid belonging to the glutamate family, using a coryneform bacterium which has been modified so that expression of one or more gene(s) of the NCgl_2067-NCgl_2065 operon in said bacterium is/are attenuated. | 02-20-2014 |
20140046022 | FLUORENE COMPOUND - Particular compounds having a fluorene skeleton are superior in broad utility and stability, as a protecting reagent for liquid phase synthesis of amino acids and/or peptides. | 02-13-2014 |
20140045247 | FUSION PROTEIN - The present invention provides means useful for making devices, materials and the like that are excellent in photocatalytic activity, electric property or the like. Specifically, the present invention provides a fusion protein comprising a polypeptide portion capable of forming a multimer having an internal cavity, and a first peptide portion capable of binding to a first target substance and a second peptide portion capable of binding to a second target substance; a multimer of the fusion protein; a complex comprising the multimer of the fusion protein; and the like. | 02-13-2014 |
20140045228 | Method for Producing L-Amino Acid - An L-amino acid is produced by culturing an Enterobacteriaceae which is able to produce an L-amino acid in a medium containing glycerol, especially crude glycerol, as the carbon source to produce and accumulate the L-amino acid in the culture, and collecting the L-amino acid from the culture. | 02-13-2014 |
20140045219 | Method for Producing Substance Utilizing Microorganism - In a method for producing a target substance utilizing a microorganism comprising culturing the microorganism in a medium to produce and accumulate the target substance in the medium and collecting the target substance, microorganism is employed, which is a mutant strain or a genetic recombinant strain constructed from a parent strain of the microorganism having a respiratory chain pathway of high energy efficiency and a respiratory chain pathway of low energy efficiency as respiratory chain pathways, and having either one or both of the following characteristics: (A) the respiratory chain pathway of high energy efficiency is enhanced, (B) the respiratory chain pathway of low energy efficiency is deficient. | 02-13-2014 |
20140044828 | NUTRITIONAL COMPOSITION - A nutritional composition is provided which has an effective prophylactic and/or improving effect for various symptoms of muscle mass decrease, decreased basal metabolism, low body temperature, suppression of obesity, suppression of visceral fat accumulation, hyperglycemia, hyperlipidemia and the like in elderly people. The nutritional composition can include n-3 fatty acid and one or more of free lysine, dipeptides containing lysine, and lysine salts, wherein the content of free lysine, dipeptides containing lysine, and/or lysine salts is 0.1 g-10.0 g per 100 kcal of the composition, and the content of the total amount of n-3 fatty acid is 0.17 g-5.00 g per 100 kcal of the composition. | 02-13-2014 |
20140030380 | Manufacturing Method for Food With Enhanced Taste and Method for Enhancing Taste of Food - The present invention provides a production method of a food, which can effectively enhance a taste without conferring an unpreferable or undesirable flavor, and a method for enhancing a taste of food. The present invention provides a method of producing a food with an enhanced taste, including by adding a peptide mixture obtained by hydrolyzing, with an enzyme, a composition containing β-conglycinin, and a method of enhancing the taste of food, including a step of adding the peptide mixture. | 01-30-2014 |
20140005359 | BRANCHED CHAIN-CONTAINING AROMATIC COMPOUND | 01-02-2014 |
20140004243 | SALTY TASTE ENHANCER | 01-02-2014 |
20130344526 | Method of Analyzing L-Tryptophan in Biological Samples, and Kit Used Therein - Disclosed is a method for quantifying L-tryptophan involving a step for mixing a specimen, L-tryptophan oxidase, and water, a step for allowing the obtained reaction solution to stand a predetermined period of time in the presence of oxygen, and a step for measuring the reaction product resulting from action of enzymes present in the reaction solution after allowing to stand. The L-tryptophan oxidase has a given amino acid sequence and has oxidase activity that generates hydrogen peroxide and ammonia by acting on the L-tryptophan in the presence of oxygen and water. The oxidase activity of the L-tryptophan oxidase on the L-phenylalanine is in the range of 0-3% of the oxidase activity thereof on the L-tryptophan, and the L-tryptophan oxidase does not have oxidase activity on protein-constituting amino acids other than L-tryptophan and L-phenylalanine. Also disclosed are a kit used to quantify the L-tryptophan containing L-tryptophan oxidase, and an enzyme sensor using the L-tryptophan oxidase. This method, kit and enzyme sensor use an L-tryptophan-specific enzyme, so are capable of quantifying L-tryptophan even in the presence of other amino acids. | 12-26-2013 |
20130338132 | HETEROARYLCARBOXYLIC ACID ESTER DERIVATIVE - Compounds represented by the following formula (I), | 12-19-2013 |
20130337511 | Method for Producing Pyrroloquinoline Quinone Using a Bacterium of the Genus Methylobacterium or Hyphomicrobium - The present invention provides a method for producing PQQ using a bacterium belonging to the genera | 12-19-2013 |
20130319749 | PRODUCTION METHOD OF MULTILAYER PRINTED WIRING BOARD AND MULTILAYER PRINTED WIRING BOARD - Multilayer printed wiring boards may be prepared by forming a via hole by laser irradiation in insulating layer formed by a prepreg, comprised of a glass cloth impregnated with a thermosetting resin composition, and subjecting the via hole to a glass etching treatment with a glass etching solution and then to a desmear treatment with an oxidizing agent solution. By such a process, etch back phenomenon and excessive protrusion of glass cloth from the wall surface of a via hole can be sufficiently suppressed, and a highly reliable via can be formed. Particularly, a highly reliable via can be formed in a small via hole having a top diameter of 75 μm or below. | 12-05-2013 |
20130316401 | Method for Modifying a Property of a Protein - A method for improving the thermostability of a protein includes introducing, into the protein, two or more amino acid substitutions selected from the group consisting of: (i) substitution of an arginine residue for a lysine residue, (ii) substitution of a threonine residue for a serine residue, and (iii) substitution of an alanine residue for a serine residue. | 11-28-2013 |
20130259981 | FROZEN GYOZA AND REFRIGERATED GYOZA WITH BROWNING AGENT, AND METHOD FOR PRODUCING THE SAME - Frozen or refrigerated gyoza having an improved quality can be produced by forming a layer of a browning agent on a portion of a gyoza, such that the browning agent has a net-like structure and the structure properties of the net-like structure is used as an index. | 10-03-2013 |
20130259407 | PROCESS OF FUSION-BONDING PLASTIC FILM AND DRUG BAG - The present invention relates to a process of fusion-bonding a plastic film ( | 10-03-2013 |
20130252310 | NOVEL ALDOLASE AND PRODUCTION PROCESS OF SUBSTITUTED ALPHA-KETO ACIDS - 4-(Indol-3-ylmethyl)-4-hydroxy-2-oxoglutarate, which is useful as an intermediate in the synthesis of monatin, may be synthesized from indole pyruvic acid and pyruvic acid (and/or oxaloacetic acid) by using a novel aldolase derived from the genus | 09-26-2013 |
20130243933 | NUTRIENT COMPOSITION - The present invention relates to a nutrient composition which contains at least a carbohydrate, a lipid, a protein, and a mineral, and is liquid or semisolid, characterized in that the volume-based median size (d50) of particles in the nutrient composition is 5 to 100 μm and water-insoluble particles having a protein insolubilized by a divalent cation are contained as a major component of the nutrient composition, or a nutrient composition which contains at least a carbohydrate, a lipid, a protein, and a mineral, and is liquid or semisolid, characterized in that water-insoluble particles having a protein insolubilized by a divalent cation are contained as a major component of the nutrient composition and the mass of the protein with respect to the total moles of divalent ions forming the water-insoluble particles is 1.5 to 3 g/mmol. | 09-19-2013 |
20130237702 | ALKYLAMINE DERIVATIVE - A composition containing a compound represented by General Formula (I) below (see the definition in the specification for the symbols in the formula) or a salt thereof has an excellent CaSR agonistic effect and provides a pharmaceutical agent, a CaSR agonistic agent, a prophylactic or therapeutic agent for a disease that can be ameliorated through CaSR activation as well as seasonings and an agent for imparting kokumi. | 09-12-2013 |
20130236627 | COFFEE WHITENER, PROCESS FOR PRODUCING SAME, AND PROCESS FOR PRODUCING BEVERAGE - Coffee whiteners prepared by using, as the aqueous phase thereof, a casein-containing milk protein solution that has been deamidated with a protein deamidating enzyme, exhibit excellent storage stability and dispersibility in coffee without the use of synthetic emulsifiers. | 09-12-2013 |
20130231402 | POLYSACCHARIDES AND EMULSIFIED PRODUCTS CONTAINING THE SAME - To provide a novel substance having an excellent water-dispersibility capable of forming an emulsion which spreads rapidly onto the skin, does not undergo aggregation or segregation due to a salt, and is excellent in a low temperature stability. The aforementioned problems were found to be solved by means of a certain polysaccharide and the invention was established. | 09-05-2013 |
20130224806 | Method for Producing an L-Amino Acid Using a Bacterium of the Enterobacteriaceae Family - A method for producing an L-amino acid is described using a bacterium of the Enterobacteriaceae family, wherein the bacterium contains a protein which is able to confer resistance to growth inhibition by L-cysteine. | 08-29-2013 |
20130196050 | SALTY TASTE ENHANCER - Compounds represented by formula (I): | 08-01-2013 |
20130183406 | METHOD FOR PRODUCING FROZEN BREAD DOUGH WHICH DOES NOT REQUIRE THAWING OR FERMENTATION STEP - Provided is shaped frozen bread dough from which a baked bread product having favorable post-baked qualities (taste, texture, flavor, appearance (voluminousness), and the like) can be prepared using a commonly employed baking facility, without requiring a special facility for thawing and fermenting. A bread dough having a continuous, multi-layered structure is prepared by using a cereal flour composition containing yeast and an oil-and-fat composition (roll in oil-and-fat), the bread dough is formed into a desired shape, and then a dent is made on the surface of the thickest portion having the length which is 13% to 70% of the longitudinal length of the shaped article. | 07-18-2013 |
20130171700 | L-Amino Acid-Producing Bacterium and Method for Producing L-Amino Acid - An L-amino acid is produced by culturing a | 07-04-2013 |
20130164793 | SULFUR-CONTAINING AMINO ACID-PRODUCING BACTERIUM AND METHOD FOR PRODUCING SULFUR-CONTAINING AMINO ACID - A novel technique for improving the production by bacteria of amino acids that contain sulfur has been developed, and thereby a sulfur-containing amino acid-producing bacterium, and a method for producing a compound such as a sulfur-containing amino acid are provided. A sulfur-containing amino acid, a related substance thereof, or a mixture of these can be produced by culturing a bacterium belonging to the family Enterobacteriaceae, which has a sulfur-containing amino acid-producing ability and has been modified so that the activity of the protein encoded by the yeeE gene, for example, the protein of the following (A) or (B), is increased in a medium, and collecting a sulfur-containing amino acid, a related substance thereof, or a mixture of them from the medium: (A) a protein having the amino acid sequence of SEQ ID NO: 14, (B) a protein having the amino acid sequence of SEQ ID NO: 14 but which includes one or several amino acid substitutions, deletions, insertions, or additions, and when the intracellular activity of this protein is increased, the ability of the bacterium to produce a sulfur-containing amino acid is improved. | 06-27-2013 |
20130164792 | METHOD FOR PRODUCING CRYSTALS OF MUTIVALENT METAL SALT OF (2R, 4R) MONATIN - The present invention provides a method of efficiently producing a crystal of a (2R,4R)Monatin multivalent metal salt that has a good sweetness property and is excellent in storage stability. Specifically, the present invention provides the method of producing the crystal of the (2R,4R)Monatin multivalent metal salt comprising allowing an aldehyde or one or two or more enzymes capable of forming (2R,4R)Monatin from (2S,4R)Monatin to be acted on an aqueous solution containing the (2S,4R)Monatin in the presence of a multivalent metal ion to obtain the crystal of the (2R,4R)Monatin multivalent metal salt. The aldehyde may preferably be an aromatic aldehyde. The one or two or more enzyme may preferably be a racemase or one or more aminotransferases. The multivalent metal may preferably be a bivalent alkaline earth metal. | 06-27-2013 |
20130157342 | NOVEL ALDOLASE AND PRODUCTION PROCESS OF SUBSTITUTED ALPHA-KETO ACIDS - 4-(Indol-3-ylmethyl)-4-hydroxy-2-oxoglutarate, which is useful as an intermediate in the synthesis of monatin, may be synthesized from indole pyruvic acid and pyruvic acid (and/or oxaloacetic acid) by using a novel aldolase derived from the genus | 06-20-2013 |
20130157321 | Use of Phosphoketolase for Producing Useful Metabolites - The present invention provides a bacterium which has an ability to produce a useful metabolite derived from acetyl-coenzyme A, such as L-glutamic acid, L-glutamine, L-proline, L-arginine, L-leucine, L-cysteine, succinate, and polyhydroxybutyrate, wherein said bacterium is modified so that activities of D-xylulose-5-phosphate phosphoketolase and/or fructose-6-phosphate phosphoketolase are enhanced. The present invention also provides a method for producing the useful metabolite using the bacterium. | 06-20-2013 |
20130143262 | METHOD FOR PRODUCING PEPTIDE - Peptides may be produced by allowing (A) a first amino acid or peptide, which is converted into its ionic liquid form, (B) a second amino acid or peptide, and (C) a peptide hydrolase to simultaneously exist in a single reaction system, wherein the first amino acid or peptide, which is converted into its ionic liquid form, is used as both a reaction solvent and a reaction starting material; and forming a peptide bond between the first amino acid or peptide and the second amino acid or peptide. By such a process, it is possible to synthesize a peptide at a high concentration and at a high yield, and the method is excellent for producing peptides on an industrial scale. | 06-06-2013 |
20130137853 | METHOD FOR PRODUCING PEPTIDE - Peptides may be produced by using (A) a first amino acid or peptide, which is converted into its ionic liquid form through the formation of an ionic bond, as a substance serving as both a reaction solvent and a reaction starting material; and reacting the first amino acid or peptide with (B) an ester of second amino acid or peptide, in the absence of any peptide hydrolase or any condensation agent, in the presence of water in an amount of not more than 20% by mass relative to the total mass of the reaction system to form a peptide bond between the first amino acid or peptide and the second amino acid or peptide. By means of this process, it is possible to synthesize a peptide at a high concentration and at a high yield, and this method is excellent for producing peptides on an industrial scale. | 05-30-2013 |
20130131179 | IRON METABOLISM-IMPROVING AGENT - An acetic acid- and/or acetate salt-free iron metabolism-improving agent that contains citric acid and/or a citrate salt as electrolytes and also contains another/other electrolyte/electrolytes and glucose solely or in combination is provided. The iron metabolism-improving agent can be formulated into a dialysate and/or a substitution fluid. A method for improving internal iron metabolism and a blood purification method including hemodialysis and hemodiafiltration in a chronic renal failure patient employing the dialysate and/or the substitution fluid are further provided. | 05-23-2013 |
20130130277 | REMEDY FOR DIABETES - A method of screening a compound having a hypoglycemic effect (hereinafter referred to as “hypoglycemic compound”), a remedy for diabetes which contains a compound having a novel function mechanism, etc. More specifically speaking, a method of screening a hypoglycemic compound capable of binding to the β subunit of a trimeric GTP-binding protein, a remedy for diabetes comprising a hypoglycemic compound, which is characterized by being capable of binding to the β subunit of a trimeric GTP-binding protein, as the active ingredient, etc. | 05-23-2013 |
20130126804 | MODIFIED POLYAMINE - A pigment dispersant which includes a modified polyamine obtained by the reaction of a polyamine having two or more primary and/or secondary amino groups per molecule and containing 2 to 1800 nitrogen atoms per molecule, a polyester, and a phosphorus-containing compound. The modified polyamine exhibits excellent pigment dispersion performance, shows little change in color tone upon heating, and has excellent heat resistance. | 05-23-2013 |
20130122544 | ENZYME THAT CATALYZES A PEPTIDE-FORMING REACTION FROM A CARBOXY COMPONENT AND AN AMINE COMPONENT, MICROBE PRODUCING THE SAME, AND A METHOD OF PRODUCING A DIPEPTIDE USING THE ENZYME OR MICROBE - DNA and recombinant DNA that encode a peptide-forming enzyme, a method for producing a peptide-forming enzyme, and a method for producing a dipeptide are disclosed. A method for producing a dipeptide includes producing a dipeptide from a carboxy component and an amine component by using a culture of a microbe belonging to the genus | 05-16-2013 |
20130115332 | PROCESS FOR PRODUCTION OF FISH PASTE PRODUCT, AND ENZYME PREPARATION FOR MODIFYING FISH PASTE PRODUCT - A fish paste product imparted with firmness and flexibility can be obtained using transglutaminase, an alkali material, and an ascorbic acid compound. | 05-09-2013 |
20130109063 | Method for Producing an L-Amino Acid Using a Bacterium of the Enterobacteriaceae Family | 05-02-2013 |
20130108744 | METHOD FOR PRODUCING NON-FRIED FOOD | 05-02-2013 |
20130102570 | PROPHYLACTIC AGENT OR THERAPEUTIC AGENT FOR DIABETES OR OBESITY - A medicament having an excellent CaSR agonist action which enables the prevention or treatment of diabetes or obesity is provided by a composition comprising the compound represented by general formula (I) as defined, or a salt thereof. | 04-25-2013 |
20130095206 | FEED ADDITIVE COMPOSITION FOR RUMINANTS AND METHOD OF PRODUCING THE SAME - A food additive composition for ruminants of the dispersion type and a method of continuously producing the same. This food additive composition for ruminants, which contains 40% by weight or more but less than 65% by weight of a basic amino acid and has rumen bypass properties, is formulated into granules in an arbitrary shape which are scarcely classified when added to a silage or another feed. Thus, attempts have been made to develop a method of producing granules by which the milk yield of a lactation cow can be increased. Namely, it is intended to provide a food additive composition for ruminants which contains at least one protecting agent selected from among a hardened vegetable oil and a hardened animal oil having a melting point higher than 50° C. but lower than 90° C., 0.05 to 6% by weight of lecithin, water and 40% by weight or more but less than 65% by weight of a basic amino acid. It is also intended to provide a method of producing a food additive composition for ruminants characterized by comprising solidifying a molten mixture, which comprises at least one protecting agent selected from among a hardened vegetable oil and a hardened animal oil having a melting point higher than 50° C. but lower than 90° C., lecithin and a basic amino acid, by dipping in water. | 04-18-2013 |
20130095048 | CYSTEINE DERIVATIVE - Cysteine compounds represented by the following formula | 04-18-2013 |
20130084609 | Method for Producing an L-Amino Acid - An L-amino acid is produced by culturing a bacterium having an L-amino acid-producing ability in a medium containing a processed product of a microalga which promotes production and accumulation of the L-amino acid by the bacterium. The process product is produced by disrupting the culture of the microalga, and/or extracting the culture of the microalga, or fractionating the culture of the microalga or the disrupted culture. The processed product contains a mixture of organic substances produced by the microalga, a hydrolysate of the disrupted microalga culture, and/or an extract or fractionation product of the microalga culture. The processed product can also contain a saccarification product of starch or a hydrolysate of fats and oils. The bacterium is cultured to produce and accumulate the L-amino acid in culture, and the L-amino acid is collected from the culture. | 04-04-2013 |
20130078682 | Method for Producing an L-Amino Acid Using a Bacterium of the Enterobacteriaceae Family, Having Attenuated Expression of Gene(s) Encoding Peptidase - The present invention provides a method for producing L-amino acids, such as L-arginine, L-citrulline, and L-lysine, using a bacterium of the Enterobacteriaceae family, particularly a bacterium belonging to the genus | 03-28-2013 |
20130078681 | METHOD FOR PRODUCING AN L-AMINO ACID USING A BACTERIUM OF THE ENTEROBACTERIACEAE FAMILY HAVING ATTENUATED EXPRESSION OF GENES ENCODING A LYSINE/ARGININE/ ORNITHINE TRANSPORTER - The present invention provides a method for producing an L-amino acid using a bacterium of the Enterobacteriaceae family, particularly a bacterium belonging to genus | 03-28-2013 |
20130078228 | VITAMIN-CONTAINING NUTRITION INFUSION FOR ADMINISTRATION THROUGH PERIPHERAL VEIN - A nutrition infusion is provided for administration through a peripheral vein that contains a vitamin B group and vitamin C stably and includes two solutions of a sugar solution and an amino acid solution. In the nutrition infusion for administration through a peripheral vein, the sugar solution contains vitamin B1, vitamin B12, and pantothenic acid and has a pH of 4.7 to 5.5, and the amino acid solution contains vitamin B2, folic acid, vitamin C, and biotin and has a pH of 7.0 to 7.5. | 03-28-2013 |
20130072491 | PROPHYLACTIC OR THERAPEUTIC AGENT FOR DIABETES OR OBESITY - An object is to provide a CaSR agonist agent that has excellent CaSR agonist effects, and particularly, a pharmaceutical product that can prevent or remedy diabetes or obesity by the effect of CaSR activation. The aforementioned object is achieved by a composition that contains a compound represented by the following General Formula (I) or a salt thereof (refer to the Description for the definitions of the symbols used in the formula). | 03-21-2013 |
20130071863 | Sulfur-Containing Amino Acid Derivative - The present invention provides a method of measuring an endogenous low-molecular-weight compound specifically and conveniently with high sensitivity. Using the particular sulfur-containing amino acid derivative, a method of measuring an endogenous low-molecular-weight compound specifically and conveniently with high sensitivity can be provided. | 03-21-2013 |
20130067742 | PROCESS FOR PRODUCING MULTILAYER PRINTED WIRING BOARD - Multi-layer printed wiring boards may be produced by:
| 03-21-2013 |
20130066072 | CRYSTALS OF SALTS OF PHENYLALANINE DERIVATIVES - Provided is a crystal of a salt of the compound represented by formula (I), which is excellent in its solubility in water. In particular, also provided is a crystal of hydrochloride, hydrobromate, sulfate, nitrate, p-toluenesulfonate or methanesulfonate of the compound represented by formula (I). | 03-14-2013 |
20130053441 | NOVEL ESTER DERIVATIVE AND USE THEREOF - A compound represented by the following formula (I′) | 02-28-2013 |
20130052143 | LIQUID PREPARATION FOR ORAL ADMINISTRATION TO BE USED IN CTCOLONOGRAPHY, AND COMPOSITION FOR DIGESTIVE TRACT IMAGING - An liquid preparation for oral administration in digestive tract imaging, wherein: the preparation comprises an iodine compound, an electrolyte, and a water-soluble polymer; and the iodine content is 1.5 to 12.0 mg/mL. | 02-28-2013 |
20130045305 | YEAST EXTRACT CONTAINING GAMMA-GLU-X OR GAMMA-GLU-X-GLY AND A METHOD FOR PRODUCING THE SAME - A yeast extract containing a peptide, such as γ-Glu-X and γ-Glu-X-Gly, wherein X can represent an amino acid or an amino acid derivative other than Cys and derivatives thereof, is prepared by culturing a yeast in a medium containing a peptide such as γ-Glu-X, γ-Glu-X-Gly and X-Gly, and preparing a yeast extract from the obtained cells. | 02-21-2013 |
20130041000 | NOVEL AZOLE COMPOUND - Azole compounds represented by formula I: | 02-14-2013 |
20130030013 | PHARMACEUTICAL PREPARATION COMPRISING PHENYLALANINE DERIVATIVE - The disclosed pharmaceutical preparation comprises a compound represented by the chemical formula (A) or a pharmaceutically acceptable salt thereof, which is dispersed in a matrix consisting of a water-soluble high molecular weight substance; and Crospovidone: | 01-31-2013 |
20130023581 | ENVIRONMENTALLY ACTIVE CONCRETE - In order to reduce the amount of an organism attractant substance remaining inside concrete that tends be used wastefully and also to allow the organism attractant substance to effectively flow out gradually in a long period of time, an environmentally active, preserving and repairing-use concrete block is provided in which the air content and flowability of the concrete are increased, and the congregating and growing effects for fishes and shellfishes and the adhering and growing effects for algae are maintained so that a high attractant effect by odor of the organism attractant substance is obtained. | 01-24-2013 |
20130023563 | AMIDINOANILINE DERIVATIVE - Provided are a novel amidine derivative having an activated blood coagulation factor X inhibitory activity, a production method thereof, a production intermediate therefor, and a pharmaceutical composition containing the amidine derivative. An amidinoaniline derivative represented by the following formula (1-1) or a pharmaceutically acceptable salt thereof: | 01-24-2013 |
20130022710 | ICE CREAM OR ICE CREAM-LIKE PRODUCT AND METHOD FOR PRODUCING SAME - Provided is an ice cream or ice cream-like product, to which a good body, flavor and a smooth texture have been imparted, and a method for producing the same. In a process of producing an ice cream or ice cream-like product, a step, wherein a protein deamidating enzyme is added to a milk material or a liquid ice cream mix for treating the same to thereby deamidate milk proteins in the milk material, is employed. | 01-24-2013 |
20130017603 | GLUTAMATE DERIVATIVES OR SALTS THEREOF - Compounds having an excellent CaSR agonist activity are in demand. The invention provides glutamate derivatives or salts thereof, pharmaceutical compositions comprising the glutamate derivatives, preventive or therapeutic agents for diarrhea, hyperparathyroidism or peptic ulcer. | 01-17-2013 |
20130011873 | ENZYME THAT CATALYZES A PEPTIDE-FORMING REACTION FROM A CARBOXY COMPONENT AND AN AMINE COMPONENT, MICROBE PRODUCING THE SAME, AND A METHOD OF PRODUCING A DIPEPTIDE USING THE ENZYME OR MICROBE - DNA and recombinant DNA that encode a peptide-forming enzyme, a method for producing a peptide-forming enzyme, and a method for producing a dipeptide are disclosed. A method for producing a dipeptide includes producing a dipeptide from a carboxy component and an amine component by using a culture of a microbe belonging to the genus | 01-10-2013 |
20130011538 | CRYSTAL OF MULTIVALENT METAL SALT OF MONATIN - To provide a novel monatin crystal capable of forming a sweetener composition which is less likely to be degraded even when being exposed to high temperature and high humidity conditions in the coexistence of a reducing sugar. It was found that the object can be achieved by a crystal of a multivalent metal salt of (2R,4R)-monatin. | 01-10-2013 |
20120329846 | THERAPEUTIC AGENT FOR INFLAMMATORY BOWEL DISEASE AND TNF-ALPHA PRODUCTION INHIBITOR - Disclosed is an agent for use in the treatment or prevention of inflammatory bowel disease. Also disclosed is an agent for inhibiting the production of TNF-α. A therapeutic or prophylactic agent for inflammatory bowel disease comprising at least one amino acid selected from the group consisting of lysine, histidine, phenylalanine, methionine, tryptophan, glutamine, glycine, cysteine, cystine and threonine, the amino acid being administered at a dose of 0.1 to 4000 mg/kg per day; and a TNF-α production inhibitor comprising an amino acid selected from the group consisting of histidine, phenylalanine and tryptophan, the amino acid being administered at a dose of 0.1 to 4000 mg/kg per day. | 12-27-2012 |
20120328760 | EMULSION COMPOSITION - An emulsion composition, which contains (A) an oil phase component containing an oil-soluble component and fats and oils, (B) polyglycerol fatty acid ester, and (C) an aqueous phase component, wherein the (A) fats and oils in the oil phase component have a fatty acid composition in a weight ratio of capric acid 20 to 97, lauric acid 28 to 6000, and myristic acid 11 to 2100, relative to caprylic acid 100, has a high emulsion stability even after long-term preservation, which is sensorially superior, shows a high transparency when added to an aqueous phase system, and suppresses decomposition of an oil-soluble component having physiological functions such as a capsinoid compound. | 12-27-2012 |
20120323002 | IMIDAZOPYRIDAZINE COMPOUNDS - By searching various compounds having an inhibiting activity against IL-12/IL-23 production, the present invention provides a pharmaceutical composition or a therapeutic or preventive agent for diseases related to IL-12/IL-23 excessive production each of which comprises the compound(s) of the present invention. | 12-20-2012 |
20120315678 | MICROALGA HIGHLY ACCUMULATING STARCH, A METHOD FOR PRODUCING GLUCOSE USING THE SAME, AND A METHOD FOR PRODUCING A TARGET SUBSTANCE - Glucose is produced by hydrolyzing starch contained in a microalga which belongs to the genus | 12-13-2012 |
20120301918 | METHOD FOR PRODUCING ALPHA-L-ASPARTYL-L-PHENYLALANINE-BETA-ESTER AND METHOD FOR PRODUCING ALPHA-L-ASPARTYL-L-PHENYLALANINE-ALPHA-METHYL ESTER - A method of producing an α-L-aspartyl-L-phenylalanine-β-ester by forming the α-L-aspartyl-L-phenylalanine-β-ester from L-aspartic acid-α,β-diester and L-phenylalanine using an enzyme or enzyme-containing substance that has an ability to selectively link L-phenylalanine to an α-ester site of the L-aspartic acid-α,β-diester through a peptide bond. | 11-29-2012 |
20120296074 | PRODUCTION METHOD OF OLIGONUCLEOTIDE - The problem of the present invention is provision of a method of producing an n+p-mer oligonucleotide efficiently in a high yield, which includes use of, as a starting material, an n-mer oligonucleotide wherein the 3′-terminal hydroxyl group is protected, and the 5′-terminal hydroxyl group is protected by a temporary protecting group, and continuously performing, in a solution, (1) a deprotection step of the 5′-terminal hydroxyl group, (2) a 5′-terminal elongation step by the addition of a p-mer oligonucleotide wherein the 3′-position is phosphoramidited, and (3) an oxidation step or a sulfurization step of a phosphite triester moiety. | 11-22-2012 |