Texas Tech University System Patent applications |
Patent application number | Title | Published |
20160104582 | PERIODIC NANOSTRUCTURES FOR HIGH ENERGY-DENSITY AND HIGH POWER-DENSITY DEVICES AND SYSTEMS AND USES THEREOF - Periodic nanostructures for high energy-density and high-power density device and systems and uses thereof. Hierarchical nanostructured materials having stacked polymer nanowires forests interconnected by monolayer graphene sheets were fabricated through bottom-up nanofabrication. Driven by external voltage, aniline molecules and graphene oxide were alternatively assembled for hierarchical porous stacked nanostructures while graphene oxide was in-situ reduced to graphene during the assembly process. As-produced hierarchical nanostructures can be used as supercapacitor electrodes, which can utilize the discovered stack-dependent device properties. | 04-14-2016 |
20160090823 | FRACTURABILITY INDEX MAPS FOR FRACTURE PLACEMENT AND DESIGN OF SHALE RESERVOIRS - Methods and systems for generating a fracturability index for use in identifying fracture locations and propagation in subterranean formations. A well path can be divided into a plurality of segments and the order of fracture locations along the path can be identified. Such an order is based on an optimal fracture stage from a production point of view followed by subsequent fracture stages. The above steps or operations can be repeated with respect to additional paths to generate data for use in determining prioritized segments and identifying fracture locations and propagation in subterranean formations. Such data can be compiled in the context of a fracturability index map. | 03-31-2016 |
20160030343 | PREPARATION AND CHARACTERIZATION OF BONE-TARGETED VANCOMYCIN-LOADED LIPOSOMES FOR OSTEOMYELITIS TREATMENT - A treatment method, system, and compound comprise directly targets osteomyelitis-infected bone tissue with one or more surface-modified liposomes. The surface-modified liposome(s) includes an alendronate targeting moiety utilized to modify the surface of the liposome. Alendronate targets hydroxyapatite in bone tissue, wherein the surface-modified liposome further comprises encapsulated vancomycin that directly targets the hydroxyapatite in the infected bone tissue and prevents bone implant related infection. | 02-04-2016 |
20150056252 | Composition and Method for Diagnosis and Immunotherapy of Lung Cancer - The present invention includes compositions and methods for the diagnosis and treatment of lung cancer with a recombinant tumor-associated antigen loaded antigen presenting cell that generates a cytotoxic T lymphocyte specific immune response to at least one of SP17, AKAP-4, or PTTG1 expressed by one or more lung cancer cells. | 02-26-2015 |
20140248605 | BACTERIAL CHALLENGE MODEL IN CATTLE USING A TRANS- AND INTRA-DERMAL ROUTE TO INFECT PERIPHERAL LYMPH NODES - The present invention includes a method of observing and evaluating bacterial infections within the lymph nodes of animals presented for harvest comprising: inoculating at one or more sites of an animal a known amount of a pathogen, wherein the one or more inoculation sites comprise lymph node drainage areas, and at one or more time points obtaining one or more lymph node biopsies to determine the extent of the pathogen in the lymph nodes. | 09-04-2014 |
20140243275 | Galectin-3C Combination Therapy for Human Cancer - The present invention provides a novel composition of matter useful for the treatment of neoplastic diseases. The novel composition is synergistic and comprised of galectin-3C in combination with a proteosome inhibitor, the combination having a pharmacologic activity greater than the expected additive effect of its individual components. Other embodiments of the invention provide novel synergistic compositions of galectin-3C with a proteasome inhibitor capable of reducing or overcoming resistance that develops to the proteasome inhibitor or reducing the adverse side effects from the proteasome inhibitor through increasing the therapeutic efficacy of lower doses. | 08-28-2014 |
20140199697 | QUANTIFICATION AND MOLECULAR DETECTION OF LACTIC ACID BACTERIA IN A SAMPLE - Methods and compositions are disclosed for detection of probiotic bacteria strains intentionally provided to animals comprising: providing an animal with a known amount or number of probiotic bacteria; following a pre-determined time, obtaining a biological sample suspected of comprising the inoculated probiotic bacteria from the animal; and quantitatively detecting the amount of probiotic bacteria in the biological sample. | 07-17-2014 |
20140134241 | TCR Mimic Antibodies as Vascular Targeting Tools - The present invention includes a method of delivering a therapeutic agent into and across an endothelial cell (EC) in a subject in need thereof, comprising: identifying a subject in need for treatment of a cancer in the brain; attaching to a TCR mimic an active agent to form a therapeutic agent; and administering to the subject the therapeutic agent in a pharmaceutically acceptable carrier, wherein the therapeutic agent effectively crosses the blood-central nervous system microvascular barrier. | 05-15-2014 |
20140134191 | TCR Mimic Antibodies as Vascular Targeting Tools - The present invention includes a method of delivering a therapeutic agent into and across an endothelial cell (EC) in a subject in need thereof, comprising: attaching to a T Cell receptor mimic (TCR mimic) an active agent to form a therapeutic agent; and administering to the subject the therapeutic agent in a pharmaceutically acceptable carrier, wherein the therapeutic agent effectively crosses the EC microvascular barrier. Furthermore, the present invention relates to methods of treating diseases (particularly neuronal diseases) or conditions comprising identifying a subject in need of such a treatment and administering to said subject a composition comprising a TCR mimic conjugated to an active agent. | 05-15-2014 |
20140109039 | Method, Apparatus and Computer Program Product for Automatically Generating a Computer Program Using Consume, Simplify and Produce Semantics with Normalize, Transpose and Distribute Operations - A code generator and multi-core framework are executable in a computer system to implement methods as disclosed herein, including a method for the code generator to automatically generate multi-threaded source code from functional specifications, and for the multi-core framework, which is a run time component, to generate multi-threaded task object code from the multi-threaded source code and to execute the multi-threaded task object code on respective processor cores. The methods provide transparency to the programmer, and during execution, provide automatic identification of processing parallelisms. The methods implement Consume-Simplify-Produce and Normalize-Transpose-Distribute operations to reduce complex expression sets in a functional specification to simplified expression sets operable in parallel processing environments through the generated multi-threaded task object code. The result is a code generator which compiles transparent declarative code into multi-threaded code and that in the process identifies and assigns parallel processing paths to improve overall processing performance. | 04-17-2014 |
20140105961 | IMMUNOMODULATION USING SPORES AND POLLEN GRAINS - The present invention includes compositions, methods of making and using the compositions for modulating the immune response in a subject by providing a vaccine composition having a pollen/spore disposed in a pharmaceutical carrier for delivery to a subject, wherein the pollen/spore comprises multiple pores that connect an outer surface of the pollen/spore to an inner cavity and one or more antigens disposed on the outer surface, in the inner cavity, in the multiple pores, or a combination thereof, wherein the one or more antigens modulate an immune responses in the subject. | 04-17-2014 |
20140082995 | METHODS AND SYSTEMS TO PRODUCE BIODIESEL FUEL - A method of manufacturing a biodiesel fuel that comprises mixing a co-solvent, a first reactant and a second reactant together in a mixing chamber to form a homogeneous solution. The first reactant and the second reactant are substantially immiscible with each other in the absence of the co-solvent. The first reactant is one of an alcohol or an oil, and the second reactant is the other of the oil or the alcohol. Method also comprises transferring the homogeneous solution into a transesterification reaction vessel. | 03-27-2014 |
20140082376 | System, Method and Apparatus for Securely Saving/Retrieving Data on a Data Storage - A system, method and apparatus securely save data by receiving a file from a user device, wherein the file contains an encrypted data and has a file name. The encrypted data is then split into two or more encrypted data chunks having a specified size. A chunk number is assigned to each of the two or more encrypted data chunks. Each of the two or more encrypted data chunks is saved in a chunk file having a chunk file name comprising a combination of the file name and the chunk number. Each chunk file name is then encrypted, and each chunk file having the encrypted chunk file name is sent to the data storage. The process is essentially reversed to retrieve the data. | 03-20-2014 |
20140075596 | siRNAS Compositions and Method for Manipulating Berry Ripening - The present invention provides a method and compositions of regulating plant development and secondary metabolite biosynthesis by providing one or more plant cells; providing a small interfering RNAs (ta-siRNAs) to the one or more plant cells; targeting a transcription factor to affect the plant development and/or secondary metabolite biosynthesis. | 03-13-2014 |
20140051062 | Methods and Devices to Control Fluid Volumes, Reagent and Particle Concentration in Arrays of Microfluidic Drops - The present invention includes a microfluidic device comprising one or more parking loops | 02-20-2014 |
20140048270 | Methods and Devices for Hydraulic Fracturing Design and Optimization: A Modification to Zipper Frac - The present invention provides a method of optimizing the placement of fractures along deviated wellbores by identifying at least two parallel lateral wellbores in a subterranean formation comprising at least a first wellbore and a second wellbore; introducing a first fracture and a second fracture in the first wellbore; introducing a third fracture in the second wellbore between the first fracture and the second fracture, wherein the third fracture extends to an intermediate area between the first two fractures and alters the stress field in that region; and forming one or more complex fractures extending from the first fracture, the second fracture, the third fracture or a combination thereof to form a complex fracture network. | 02-20-2014 |
20140028496 | APPARATUS AND METHOD FOR USING RADAR TO EVALUATE WIND FLOW FIELDS FOR WIND ENERGY APPLICATIONS - The present invention provides an apparatus and method for obtaining data to determine one or more characteristics of a wind flow field using one or more radars. Data is collected from the one or more radars, and analyzed to determine the one or more characteristics of the wind flow field. The one or more radars are positioned to have a portion of the wind flow field within a scanning sector of the one or more radars. | 01-30-2014 |
20140028495 | System and Method for Evaluating Wind Flow Fields Using Remote Sensing Devices - The present invention provides a system and method for obtaining data to determine one or more characteristics of a wind field using a first remote sensing device and a second remote sensing device. Coordinated data is collected from the first and second remote sensing devices and analyzed to determine the one or more characteristics of the wind field. The first remote sensing device is positioned to have a portion of the wind field within a first scanning sector of the first remote sensing device. The second remote sensing device is positioned to have the portion of the wind field disposed within a second scanning sector of the second remote sensing device. | 01-30-2014 |
20130292687 | Structures and Devices Based on Boron Nitride and Boron Nitride-III-Nitride Heterostructures - The present invention relates to optoelectronic device layer structures, light emitting devices, and detectors based upon heterostructures formed between hexagonal boron nitride (hNB) and III nitrides, and more particularly, to heterojunction devices capable of emitting and detecting photons in the ultraviolet (UV) and extremely ultraviolet (RUV) spectral range. The present invention also relates to neutron detectors based on epitaxially grown hBN thin films (or epitaxial layers) and hBN stacked thin films (or epitaxial layers) to satisfy the thickness required for capturing all incoming neutrons. | 11-07-2013 |
20130292685 | Structures and Devices Based on Boron Nitride and Boron Nitride-III-Nitride Heterostructures - The present invention relates to optoelectronic device layer structures, light emitting devices, and detectors based upon heterostructures formed between hexagonal boron nitride (hNB) and III-nitrides, and more particularly, to heterojunction devices capable of emitting and detecting photons in the ultraviolet (UV) and extremely ultraviolet (RUV) spectral range. The present invention also relates to neutron detectors based on epitaxially grown hBN thin films (or epitaxial layers) and hBN stacked thin films (or epitaxial layers) to satisfy the thickness required for capturing all incoming neutrons. | 11-07-2013 |
20130259085 | Detection of Carbon Nanotubes by Microwave-Induced Heating - The present invention includes a method, systems and devices for the detection of carbon nanotubes in biological samples by providing a sample suspected of having one or more carbon nanotubes; irradiating the sample with a microwave radiation, wherein the carbon nanotubes absorb the microwave radiation; and detecting and measuring the one or more thermal emissions from the carbon nanotubes. | 10-03-2013 |
20130217691 | Compositions and Methods for Treating Hyperproliferative Disorders - A method of treating a hyperproliferative disorder in a subject in need of such treatment, comprising administering to said subject, in combination, a treatment effective amount of: (a) a ceramide-increasing retinoid such as fenretinide or a pharmaceutically acceptable salt thereof; and (b) at least one (and in certain embodiments at least two) compounds selected from the groups consisting of (i) a non-18 carbon chain length L-threo-sphinganine(s) or pharmaceuticeutically acceptable salt thereof, (ii) glucosylceramide or glucosyl(dihydro)ceramide synthesis inhibitor(s), and (iii) sphingomyelin or dihydrosphingomyelin synthase inhibitor(s). Preferred L-threo-sphinganines are of carbon chain length 17 carbons, 19 carbons and 20 carbons. A preferred glucosylceramide or glucosyl(dihydro)ceramide synthesis inhibitor is D-threo-1-phenyl-2-palmitoylamino-3-morpholino-1-propanol. A preferred sphingomyelin or dihydrosphingomyelin synthesis inhibitor is D-threo-1-phenyl-2-palmitoylamino-3-morpholino-1-propanol. A preferred hyperproliferative disorder is brain cancers. | 08-22-2013 |
20130165770 | System, Method and Apparatus for Tracking Targets During Treatment Using a Radar Motion Sensor - A system, method and apparatus tracks targets (e.g., tumors) during treatment (e.g., radiation therapy) using a radar motion sensor by generating a microwave signal, radiating the microwave signal to a subject, and receiving a modulated microwave signal from the subject. The modulated microwave signal is processed to provide a subject motion information using a sensor having an arctangent-demodulation microwave interferometry mode. A location of a target on or within the subject is determined based on the subject motion information and a three-dimensional model for the subject and the target. One or more control signals are generated based on the location of the target, and the treatment device is controlled using the one or more control signals to treat the target on or within the subject. | 06-27-2013 |
20130087069 | ANTIBACTERIAL METALLIC NANOFOAM AND RELATED METHODS - Antibacterial metallic nanofoams, substrates having the nanofoam coated thereon, methods for preventing, inhibiting, and/or killing bacterial growth using the metallic nanofoams, and compositions and methods for making the metallic nanofoams. | 04-11-2013 |
20130011909 | METHODS AND COMPOSITION TO ENHANCE PRODUCTION OF FULLY FUNCTIONAL P-GLYCOPROTEIN IN PICHIA PASTORIS - The present invention provides codon optimization to increase protein production by providing a target gene, wherein the expression of the target gene is to be optimized; determining one or more low-frequency codons in the target gene; providing a codon usage frequency table; replacing each of the one or more low-frequency codons in the target gene with a corresponding high-frequency codons that code for the same amino acid; and harmonizing the a distribution of codon frequencies to those of the set of highly expressed native gene over an open reading frame in the target gene to form an optimized gene, wherein the optimized gene encodes an amino acid sequence identical to the respective wild-type (native) amino acid sequence. | 01-10-2013 |
20120263757 | COMPOSITION AND METHOD FOR DIAGNOSIS AND IMMUNOTHERAPY OF PROSTATE CANCER - A method and composition for the diagnosis of and treatment of prostate cancer including a recombinant AKAP-4 tumor-associated antigen loaded antigen presenting cell that generates an AKAP-4 specific cytotoxic T lymphocyte specific for one or more prostate cancer cells. | 10-18-2012 |
20110091507 | SCHISTOSOMIASIS VACCINE COMPOSITIONS AND METHODS OF USE - No effective vaccine exists for the devastating parasitic disease of Schistosomiasis. The present invention focuses on Sm-p80, a functionally important antigen of | 04-21-2011 |
20110061289 | METHODS AND SYSTEMS TO PRODUCE BIODIESEL FUEL - A method of manufacturing a biodiesel fuel that comprises generating micro-droplets of a first reactant and mixing the micro-droplets of the first reactant with a second reactant that is substantially immiscible with the first reactant. The method also comprises transferring the mixture of the first reactant and second reactant into a transesterification reaction vessel. The first reactant is one of an alcohol or oil, and the second reactant is the other of the oil or the alcohol. | 03-17-2011 |
20100289879 | Remote Contactless Stereoscopic Mass Estimation System - A contactless system and method for estimating the mass or weight of a target object is provided. The target object is imaged and a spatial representation of the target animal is derived from the images. A virtual spatial model is provided of a characteristic object of a class of object to which the target object belongs. The virtual spatial model is reshape to optimally fit the spatial representation of the individual animal. Finally, the mass or weight of the target object is estimated as a function of shape variables characterizing the reshaped virtual object. | 11-18-2010 |
20100144030 | Method and Apparatus for Gender Selection Based on pH - The present invention includes methods and apparatus to separate X or Y-chromosome bearing sperm cells in a population by first placing the population of sperm cells at physiological pH environment, and simultaneously contacting the population of sperm cells with one or more additional sub-environments with different pH values. The exposure allows mobile sperm cells bearing X or Y-chromosome to migrate to the different pH sub-environments, wherein each cell only exposed or come in contact with one pH sub-environment. Finally, the collecting X or Y-chromosome enriched population of sperm cells is performed. | 06-10-2010 |
20100099731 | Use of Endothelial Interrupters in the Treatment of Neurodegenerative Diseases - In various embodiments, the present invention relates generally to methods of treating at least one neurodegenerative disease by administering a medicament comprising an endothelial interrupter. | 04-22-2010 |
20090203003 | INHIBITION OF METALLO-BETA-LACTAMASE - A method to identify a high affinity nucleic acid ligand to inhibit the activity of a lactamase enzyme. The method comprises several steps that initially involve preparing a candidate mixture of nucleic acids. The candidate mixture of nucleic acids is then allowed to make contact with the lactamase enzyme under controlled conditions of temperature, ionic strength and pH; the combination forms a candidate-enzyme mixture. The target nucleic acids are partitioned from the remainder of the candidate mixture. The target nucleic acids that have been partitioned are amplified to yield a pool of nucleic acids enriched with target nucleic acid sequences. The enriched pool of target nucleic acids have a relatively higher affinity and specificity for binding to the lactamase, whereby nucleic acid ligand of the lactamase are identified. Nucleic acid ligands that inhibit an activity of lactamase. The lactamase includes class B, metallo-β-lactamase. | 08-13-2009 |
20090092708 | METHOD AND SYSTEM FOR PRESERVING FOOD - The present invention includes a method for extending the shelf-life of one or more foods by exposure to one or more pulses of microwave radiation for at least seven (7) seconds. The present invention may also be used to reduce pathogenic organisms in food. The one or more foods may be packaged within a container, sealed and stored. | 04-09-2009 |
20080241281 | Compositions & methods for activation and inhibition of Staphylococcus aureus biofilm development - Botanical extracts and derivative compositions are described for activating or inhibiting the formation and development of bacterial biofilms. Gymnemic acids and other associated saponins are isolated from botanical extractions of the | 10-02-2008 |
20080213350 | Encapsulation of nucleic acids in liposomes - Complexes of nucleic acid and cationic polymer, which are encapsulated in liposomes for the purpose of delivering nucleic acid and methods for producing encapsulated complexes. | 09-04-2008 |
20080197450 | AMORPHOUS CARBON METAL-TO-METAL ANTIFUSE WITH ADHESION PROMOTING LAYERS - A metal-to-metal antifuse having a lower metal electrode, a lower thin adhesion promoting layer disposed over the lower metal electrode, an amorphous carbon antifuse material layer disposed over the thin adhesion promoting layer, an upper thin adhesion promoting layer disposed over said antifuse material layer, and an upper metal electrode. The thin adhesion promoting layers are about 2 angstroms to 20 angstroms in thickness, and are from a material selected from the group comprising Si | 08-21-2008 |