Modular Genetics, Inc. Patent applications |
Patent application number | Title | Published |
20110059487 | ENGINEERED MICROORGANISMS AND METHODS OF USE - The present invention provides, among other things, engineered microorganisms and methods that allow efficient conversion of soy carbohydrates to industrial chemicals by fermentation. In some embodiments, the invention provides microbial cells engineered to have increased efficiency in utilizing a soy carbon source (e.g., soy molasses, soy meal, and/or soy hulls) as compared to a parent cell. In some embodiments, microbial cells are engineered to have altered (e.g., increased) expression or activity of one or more carbohydrate modifying enzymes (e.g., glycosidases). In some embodiments, microbial cells are engineered to have altered localization of carbohydrate modifying enzymes (e.g., glycosidases). In some embodiments, engineered microbial cells provided herein are used to produce industrial chemicals (e.g., surfactin) using soy components as primary or sole carbon sources. | 03-10-2011 |
20110034557 | ANTIMICROBIAL COMPOSITIONS AND USES THEREOF - Antimicrobial compositions and methods of using the compositions are described herein. The compositions include an antibacterial acyl amino acid. In some embodiments, the acyl amino acid is a fatty acylated glutamate. The methods herein include methods of using acyl amino acids for treating and preventing bacterial infections. | 02-10-2011 |
20090298130 | LADDER ASSEMBLY AND SYSTEM FOR GENERATING DIVERSITY - The present invention provides novel methods of generating a nucleic acid molecule. In certain embodiments, a double stranded nucleic acid chunk is generated from a ladder complex comprising partially complementary oligonucleotides, which chunk is combined with a nucleic acid acceptor molecule. In certain embodiments, the assembled chunk/nucleic acid acceptor molecule complex may be propagated in vivo or in vitro. The present invention also provides improved systems for generating a plurality of nucleic acid molecules that differ at one or more nucleotide positions. In certain embodiments, the plurality of nucleic acid molecules encodes a polypeptide or portion of a polypeptide. | 12-03-2009 |
20090269832 | Growth of Microorganisms in Media Containing Crude Glycerol - The present invention provides novel methods of growing of microorganisms in cell culture media comprising crude glycerol as a carbon source. The present invention further provides novel cell culture media comprising crude glycerol as a carbon source. In certain embodiments, inventive cell culture media substantially lack refined glycerol. In certain embodiments, inventive cell culture media comprise crude glycerol as the sole carbon source. | 10-29-2009 |
20090143242 | ALIEN SEQUENCES - The present invention provides sequences and reagents for preparing microarrays with internal controls. Specifically, the present invention defines and provides sequences that are not present in the hybridizing mRNA or cDNA, and therefore can be used both as hybridization controls and for inter-spot normalization. | 06-04-2009 |