Universite Pierre Et Marie Curie (Paris 6) Patent applications |
Patent application number | Title | Published |
20160040028 | NOVEL AMPHIPHILIC POLYMERS AND USE THEREOF IN THE TREATMENT OF SURFACES MADE OF HYDROPHOBIC MATERIALS - A straight, branched or cross-linked polymer, including, per 100 mol %: a) a mole fraction from 75% to 99.95% of monomer units from an N,N-dialkyl acrylamide; b) a mole fraction from 0.05% to 1% of monomer units from a monomer of formula (I): CH2=C(Ri)-C(=0)-0-[(CH2-CH(R2)-0]n-R3 (I); c) optionally a mole fraction higher than 0% to 24% either of monomer units from a monomer including a free strong acid function, partially or totally salified, or of monomer units from a monomer of formula (II): CH2=C(R4)-C(=0)-Y-(CH2)m-N(R5)(R6) (II); d) optionally a mole fraction higher than 0% to 1% of a diethylene or polyethylene cross-linking monomer. Also, a method for treating a surface made of a hydrophobic material, using the polymer, and an aqueous, hydro-organic or organic solution including the polymer for modifying interactions between the species contained the solution and the hydrophobic surface. | 02-11-2016 |
20160018416 | NEW DUAL BIOMARKER OF NEURODEGENERATION AND OF NEUROREGENERATION - A new dual biomarker of neurodegeneration and of neuroregeneration | 01-21-2016 |
20150343202 | BIOCOMPATIBLE CARBON BASED ELECTRODE AND ITS PREPARATION PROCESS - A biocompatible carbon based electrode, and its preparation process are described. The electrode is formed by first and second biocompatible chemically oxygen terminated or H-terminated carbon-based materials. The first material is configured to promote the growth or at least the direct interfacing of adult neurons on the first material without substantially promoting the growth and direct interfacing of glial cells on the first material. The second material presents a peptide coating to promote the growth and at least the direct interfacing of adult glial cells. | 12-03-2015 |
20150329857 | RNA INTERFERENCE TO ACTIVATE STEM CELLS - The present invention relates to the use of interferent RNAs that silence PW1 expression in order to activate adult stem cells in vitro or in vivo, in particular in the context of regenerative medicine. | 11-19-2015 |
20150302841 | HAPTIC CONTROLLER SUITABLE FOR CONTROLLING A SOUND CHARACTERISTIC - The invention relates to a haptic controller comprising a base ( | 10-22-2015 |
20150280733 | SIGMA DELTA RF MODULATOR HAVING CAPACITIVE COUPLING, ANALOG/DIGITAL CONVERTER AND APPARATUS INCLUDING SUCH A MODULATOR - A continuous-time sigma delta radio frequency modulator is provided, including at least two LC resonators coupled in parallel by a coupling capacitive element, producing an at least 4 | 10-01-2015 |
20150255639 | PHOTOVOLTAIC COMPONENT WITH A HIGH CONVERSION EFFICIENCY - A photovoltaic component that includes at least one first array of photovoltaic nano-cells is disclosed. Each photovoltaic component includes an optical nano-antenna exhibiting an electromagnetic resonance in a first resonant spectral band, at least one lateral dimension of the optical nano-antenna being subwavelength in size, and a spectral conversion layer allowing at least part of the solar spectrum to be converted to said first resonant spectral band. | 09-10-2015 |
20150119745 | METHOD FOR CHARACTERISING THE PHYSIOLOGICAL STATE OF A PATIENT FROM THE ANALYSIS OF THE CEREBRAL ELECTRICAL ACTIVITY OF SAID PATIENT, AND MONITORING DEVICE APPLYING SAID METHOD - The invention relates to a method for detecting a physiological state of a patient deviating from a reference physiological state, in which, after having determined, in each of Q frequency bands, R reference matrices PR | 04-30-2015 |
20140368633 | DEVICE FOR VIEWING A DIGITAL IMAGE - The invention relates to a device for viewing a digital image comprising means ( | 12-18-2014 |
20140354792 | ASSISTIVE DEVICE FOR POSITIONING A MEDICAL INSTRUMENT RELATIVE TO AN INTERNAL ORGAN OF A PATIENT - The invention relates to an assistive device for positioning a medical instrument ( | 12-04-2014 |
20140346901 | MINIATURE LINEAR VIBROTACTILE ACTUATOR - The invention relates to a miniature linear vibrotactile actuator comprising: a first element | 11-27-2014 |
20140336993 | MULTIPURPOSE CALCULATION COMPUTING DEVICE - A multipurpose computing device includes a solver receiving a working matrix and an initial matrix corresponding to a system of equations and residual data; and an adapter receiving the initial matrix as well as a filtering matrix and calculates a working matrix corresponding to an equation system solved by the solver. The working matrix checks a stability condition with the initial matrix, comprising a comparison of two matrix products including the filtering matrix or the transpose thereof, and the initial matrix and the working matrix, respectively. The adapter renumbers the initial matrix and the filtering matrix in order to produce a modified matrix and a modified filtering matrix using an ordering rule that is a function of a dependency condition, and recursively calculates the working matrix representation with these matrices. The solver works recursively on the working matrix to provide a solution without inverting the initial matrix. | 11-13-2014 |
20140333730 | METHOD OF 3D RECONSTRUCTION OF A SCENE CALLING UPON ASYNCHRONOUS SENSORS - A method of 3D reconstruction of a scene, including the implementation of at least two sensors each having a series of elementary receivers arranged so as to view the scene according to distinct respective solid angles and which are each sensitive to a physical characteristic of a signal received by the receiver originating from the scene. The sensors are adapted for emitting an asynchronous stream of events indicative of a modification of the signal received by one of the elementary receivers at a given instant, as well as the implementation of a 3D reconstruction algorithm having a step of pairing elementary receivers of each of the sensors utilizing signals generated by the sensors, the pairing including pairing between them events generated by each of the sensors and temporarily close together. | 11-13-2014 |
20140323425 | NUCLEOSIDE ANALOGUES FOR THE TREATMENT OF A VIRAL INFECTION, AND METHOD FOR EVALUATING THE SENSITIVITY TO SAID TREATMENT - The present invention describes the use of nucleoside analogues for the treatment of viral infections, in particular of an HIV infection, and also compositions comprising at least one of these analogues, and a method for evaluating the sensitivity to said treatment. | 10-30-2014 |
20140315269 | USE OF RECOMBINANT TYPE III "POLYKETIDE SYNTHASES" (PKS III) OF MARINE BROWN ALGAE - The present invention relates to a method for producing polyphenol compounds, i.e. phloroglucinol or one of its derivatives, with a polyketide synthase of type III (PKSIII) from a brown marine alga. The invention also relates to recombinant nucleic acids coding for a polyketide synthase of type III (PKSIII) from the brown alga | 10-23-2014 |
20140296876 | DEVICE FOR GUIDING A MEDICAL INSTRUMENT INSERTED INTO A NATURAL DUCT OR AN ARTIFICAL DUCT OF A PATIENT - The invention relates to a device for guiding a medical instrument ( | 10-02-2014 |
20140296288 | IMINO-SUGAR C-GLYCOSIDES, PREPARATION AND USE THEREOF - The present disclosure relates to iminosugar derivatives and processes for the preparation thereof. The disclosed compounds have glycosidase inhibiting properties, and are useful in the treatment of various diseases, such as type 2 diabetes, neurodegenerative diseases or lysosomal storage disorders. The present disclosure also relates to pharmaceutical compositions containing the disclosed compounds and to their use as biochemical tools. | 10-02-2014 |
20140290745 | USE OF COBALT COMPLEXES FOR PREPARING AN ACTIVE LAYER IN A PHOTOVOLTAIC CELL, AND CORRESPONDING PHOTOVOLTAIC CELL - A method for employing certain cobalt complexes as electron donors and in combination with an electron acceptor is provided for preparing an active layer in a photovoltaic conversion cell, as well as to the photovoltaic conversion cell in which the electron donor of the active layer includes such cobalt complexes. | 10-02-2014 |
20140249454 | DEVICE FOR TREATING THE SENSORY CAPACITY OF A PERSON AND METHOD OF TREATMENT WITH THE HELP OF SUCH A DEVICE | 09-04-2014 |
20140240217 | SYSTEM COMPRISING AN OCULOMETER, METHOD IMPLEMENTED ON SUCH A SYSTEM AND CORRESPONDING COMPUTER PROGRAM PRODUCT - The invention relates to a system comprising an oculometer for measuring movements of at least one eye of an operator, wherein it comprises furthermore a display for displaying, for the eye, a frame of at least one point performing a blinking, so that the operator can perform at least one smooth tracking movement of the eye while looking at the display while operating. The invention also relates to a method implemented on such a system, and a corresponding computer program product. | 08-28-2014 |
20140236621 | METHOD FOR DETERMINING A PREDICTIVE FUNCTION FOR DISCRIMINATING PATIENTS ACCORDING TO THEIR DISEASE ACTIVITY STATUS - The invention relates to a method for determining a predictive function for discriminating patients according to their disease activity status, comprising steps of: a—measuring values of biological markers for each patient of a first group of patients having a first known disease activity status, and for each patient of a second group of patients having a second known disease activity status, the measured values forming a dataset b—analyzing the dataset for identifying biological markers which are differentially expressed between the first group of patients and the second group of patients, c—among the biological markers identified at step b, determining correlated markers as markers which are correlated with other markers above a predetermined significance level, d—removing from the dataset, values measured for a biological marker identified as correlated marker, e—analyzing the dataset obtained at step d for determining a predictive function that predicts a disease activity status of a patient as a combination of values of biological markers, f—evaluating an accuracy index associated with the predictive function determined at step e, g—repeating steps d to f by selectively removing from the dataset, values measured for one or several biological marker(s) identified as correlated marker(s), so as to gradually decrease the number of biological markers in the combination of value until the accuracy index reaches an expected level. | 08-21-2014 |
20140212931 | Bacterial Iodoperoxidases from Zobellia Galactanivorans, Methods of Preparation and Uses Thereof - The present invention concerns iodoperoxidases from | 07-31-2014 |
20140207150 | ENDOSCOPIC INSTRUMENT WITH SUPPORT FOOT - The invention relates to an endoscopic instrument ( | 07-24-2014 |
20140154289 | ATTENUATED PLASMODIUM WITH DEACTIVATED HMGB2 GENE, AS VACCINE - The present invention relates to novel compositions and methods for immunizing a host against malaria using a | 06-05-2014 |
20140148480 | USE OF COUMARIN DERIVATIVES FOR THE PREPARATION OF DRUGS FOR TREATING SKIN DISEASES - A compound of formula (I-1) | 05-29-2014 |
20140118811 | METHOD AND SYSTEM FOR CONFIGURING A DEVICE FOR CORRECTING THE EFFECT OF A MEDIUM ON A LIGHT SIGNAL, METHOD, DEVICE AND SYSTEM FOR CORRECTING SAID EFFECT - A method and a system is provided for configuring a device for correcting the effect of a medium on a light signal having propagated through the medium, the device including at least one optical element whose phase profiles are individually adjustable. The configuring system and method include propagating a reference signal and a disordered signal obtained at the output of the medium through the correcting device. An interference parameter is measured and optimized by modifying the phase profile of each of the optical elements of the correcting device. A method and a system is also provided for correcting the effect of a medium on a light signal having propagated through the medium. | 05-01-2014 |
20140113366 | MICROFLUIDIC SYSTEM FOR CONTROLLING THE CONCENTRATION OF MOLECULES FOR STIMULATING A TARGET - The invention relates to a microfluidic system for controlling a card for the concentration of molecules capable of stimulating a target, for example formed by an assembly of living cells, characterized in that the system comprises a microfluidic device ( | 04-24-2014 |
20140107186 | CAPSID-FREE AAV VECTORS, COMPOSITIONS, AND METHODS FOR VECTOR PRODUCTION AND GENE DELIVERY - An isolated linear nucleic acid molecule comprising in this order: a first adeno-associated virus (AAV) inverted terminal repeat (ITR), a nucleotide sequence of interest and a second AAV ITR, wherein said nucleic acid molecule is devoid of AAV capsid protein coding sequences. The said nucleic acid molecule can be applied to a host at repetition without eliciting an immune response. Methods for producing and purifying this nucleic acid molecule, and use of the same for therapeutic purposes are also provided. | 04-17-2014 |
20140106436 | USE OF AT LEAST ONE CHELATING AGENT INTRODUCED INTO THE CULTURE MEDIUM OF MAGNETOTACTIC BACTERIA IN ORDER TO STIMULATE THE GROWTH THEREOF - The invention relates to the use of at least one chelating agent, including an iron chelating agent, in order to stimulate the growth of magnetotactic bacteria. | 04-17-2014 |
20140080206 | MICROFLUIDIC SYSTEM FOR CONTROLLING A CONCENTRATION PROFILE OF MOLECULES CAPABLE OF STIMULATING A TARGET - The invention relates to a microfluidic system for controlling a concentration profile of molecules capable of stimulating a target, for example formed by an assembly of living cells, this system comprising: -a microfluidic device ( | 03-20-2014 |
20140073916 | DEVICE FOR ASSISTING IN DETECTING ANATOMICAL FEATURES OF AT LEAST A PORTION OF A TISSUE AND METHOD FOR ASSISTING IN DETECTING ANATOMICAL FEATURES OF AT LEAST A PORTION OF A TISSUE - The invention relates to a device for assisting in detecting anatomical features of at least a portion of a tissue, in particular a retinal tissue, the device comprising means for acquiring images of said portion using optical coherence tomography (OCT), which are taken at separate angles of incidence, and detection means for detecting, in a single area of the portion studied, at least one pattern having at least one feature that varies from one image to another, the pattern being attributable to the presence of anatomical features. The invention likewise relates to a method for assisting in detecting anatomical features of at least a portion of a tissue. | 03-13-2014 |
20140069865 | METHOD FOR HIGH-THROUGHPUT SCREENING OF DROPS BY OSMOTIC EXCHANGE AND DENSITY VARIATION - This method comprises bringing drops to be separated into contact with an interface ( | 03-13-2014 |
20140065658 | Method for Monitoring A Reaction, And Reaction System For Implementing Same - The invention relates to a method for monitoring a reaction and to a reaction system which are inexpensive, compact, easy to implement, and enable the reaction medium to be fully supervised throughout the entire experiment. For this purpose, the invention relates to a reaction system, in particular for microorganism cultures, including: at least one vessel (M | 03-06-2014 |
20140033333 | TRANSGENIC PIG FOR MUTANT GUCY2D AS CONE DYSTROPHY MODEL - The present invention relates to a transgenic pig as a model for studying a cone affecting disease, in particular a cone dystrophy or cone-rod-dystrophy, wherein the pig model expresses a dominant negative guanylate-cyclase-2D (GUCY2D) protein, in particular a GUCY2D protein comprising at least one mutation responsible for the appearance of a CORD6 cone dystrophy in a human being. The invention further relates to methods by which the transgenic pig is produced, to uses of said transgenic pig or of one of its elements to identify new biomarkers of a cone affecting disease and/or new compounds for preventing or treating such a disease. Novel methods for preventing or treating a cone affecting disease or for evaluating conditions needed to alleviate such a disease are further herein described. | 01-30-2014 |
20140031417 | SKELETAL MUSCLE-SPECIFIC ENHANCER - The invention relates to a novel skeletal muscle-specific p57 regulatory element. This element is useful to drive and enhance the specific skeletal muscle expression of therapeutic genes. It is therefore provided nucleic acids and vectors comprising said enhancer element, as well as pharmaceutical compositions comprising the vectors, and uses thereof. | 01-30-2014 |
20130316033 | NOVEL BACTERIUM AND EXTRACTS OF SAID BACTERIUM AND THE USE OF SAME IN DERMATOLOGY - The present invention relates to a novel bacterial strain isolated from groundwater. The invention also relates to bacterial extracts and to the use of same in the context of the treatment of inflammations. More particularly, the present invention relates to novel compositions of interest in the treatment and the prevention of inflammatory disorders, notably dermatological pathologies. | 11-28-2013 |
20130289099 | ABCG1 GENE AS A MARKER AND A TARGET GENE FOR TREATING OBESITY - The invention relates to a method for treating obesity in a patient, which method comprises administering an effective quantity of ABCG1 inhibitor to a patient in need thereof. The invention further provides an in vitro method for determining whether a patient is at risk of developing obesity, which method comprises detecting the presence of a mutation, substitution or deletion of at least one nucleotide in ABCG1 20 gene or regulatory sequences thereof. | 10-31-2013 |
20130260283 | ORGANIC-INORGANIC HYBRID NANOFIBRES HAVING A MESOPOROUS INORGANIC PHASE, PREPARATION THEREOF BY ELECTROSPINNING, MEMBRANE, ELECTRODE, AND FUEL CELL - Organic-inorganic hybrid nanofibres comprising two phases:
| 10-03-2013 |
20130226980 | MULTIPURPOSE CALCULATION COMPUTING DEVICE - A calculation computer includes a calculator-solver receiving a working matrix representation corresponding to a system of equations, as well as residue data, and for providing a solution to the system of equations from residue data, an adapter receiving an initial matrix representation corresponding to a system of equations to be processed, as well as a filtering matrix representation, the working matrix representation forced to meet with the initial matrix representation, the adapter iteratively calculates blockwise an intermediate matrix from the initial matrix representation and from said numerical representation of a filtering matrix representation, the calculator-solver works on this intermediate matrix, blockwise, so as to provide a solution of the system of equations of the initial matrix representation, without completely inverting the latter, | 08-29-2013 |
20130210739 | BHLH PROTEINS AND THEIR USE AS DRUGS - The present invention relates to at least one protein belonging to the bHLH family and/or at least a nucleic acid molecule coding for the bHLH proteins as drug. | 08-15-2013 |
20130210094 | HETEROGENEOUS ENZYMATIC CATALYST, PROCESS FOR PREPARING SAME AND USE FOR CONTINUOUS FLOW ENZYMATIC CATALYSIS - The present invention relates to a heterogeneous enzymatic catalyst consisting of a macroprous silica monolith incorporating an enzyme immobilized by means of a compiling agent, to a process for preparing this enzymatic catalyst, to the use of the catalyst for carrying out chemical reactions by continuous flow heterogeneous enzymatic catalyst and to a process of continuous flow heterogeneous enzymatic catalysis using said catalyst. | 08-15-2013 |
20130204316 | APPARATUS FOR THE TREATMENT OF BRAIN AFFECTIONS AND METHOD IMPLEMENTING THEREOF - The present invention relates to an apparatus for the treatment of a brain affection, which comprises at least one implantable generator ( | 08-08-2013 |
20130204150 | SYSTEM FOR ELECTROENCEPHALOGRAPHIC DETECTION OF AN INADEQUACY BETWEEN THE STATE OF A PATIENT PLACED UNDER VENTILATORY SUPPORT AND THE SETTING OF THE MACHINE USED FOR THIS SUPPORT, AND USE OF THIS DETECTION TO ADJUST THE SETTING - The invention relates to a system for electroencephalographic detection of an improper adjustment of a ventilator used on a mammal. The system includes an electroencephalograph, capable of measuring, as a function of time, an electroencephalographic signal representative of a breathing process; and an input for receiving a respiratory initiation signal, different from the electroencephalographic signal, capable of indicating a respiratory initiation time. The detection system further includes means for specifying a beta frequency band comprised between 15 and 30 Hz and with a width comprising between 5 and 10 Hz; means for processing the measured electroencephalographic signal, configured for processing the measured electroencephalographic signal as it is being acquired, in the sole specified beta frequency band; and means for identifying, for each breathing cycle, an improper adjustment of the ventilator from the electroencephalographic signals processed in the sole beta frequency band. | 08-08-2013 |
20130189225 | METHODS OF INCREASING EFFICIENCY OF VECTOR PENETRATION OF TARGET TISSUE - Methods for increasing the efficiency of target tissue penetration of an adeno-associated virus (AAV) vector in a patient are provided. In some aspects, the methods involve inhibiting the interaction of the serum protein galectin 3 binding protein (G3BP) with AAV vector. Further provided are methods for reducing tissue distribution of a virus or for neutralizing a virus harbored by an organ destined for transplant, or newly transplanted, by administering a composition comprising G3BP. | 07-25-2013 |
20130184685 | METHOD FOR PREPARING RED BLOOD CELLS FOR INFUSION - The present invention relates to methods to prepare red blood cells (RBCs) for infusion to a patient. Depletion of RBCs with altered deformability is achieved by filtration through micro-bead filters. | 07-18-2013 |
20130183706 | Method for Culturing Adipocytes - The present invention relates to a method for culturing adipocytes, in which a homogeneous population of mature adipocytes isolated from adipose tissue is cultured on a three-dimensional culture substrate. | 07-18-2013 |
20130172860 | SURGICAL INSTRUMENT IN PARTICULAR FOR PERITONEAL SURGERY - A surgical instrument comprising an elongate body which ends with a tool carrier and which is intended to be introduced into the peritoneal cavity by way of a trocar, the body comprising:
| 07-04-2013 |
20130171356 | METHOD FOR DEPOSITING A LAYER ON THE SURFACE OF A SUBSTRATE - A process for depositing a layer on at least part of the surface of a substrate by at least partially submerging the substrate in a solution comprising a solvent and at least one compound intended to form the layer, then drying the substrate, this drying being at least partially carried out in an atmosphere that is isolated from the solution. The submersion in the solution and the drying of the substrate are carried out in the same controlled-atmosphere enclosure. | 07-04-2013 |
20130160151 | TRANSGENIC ANIMAL AS A MODEL FOR IDENTIFYING ADULT STEM CELLS, AND USES THEREOF - The present invention relates to the use of a transgenic non-human animal, such as a mouse, expressing a reporter gene detectable by a chromogenic, luminescent or fluorescent signal which identifies the cells that express Pw1, or of Pw1-expressing cells or tissues isolated therefrom, as a model for screening a candidate substance for its ability to stimulate adult stem cells, or for monitoring cell aging. | 06-20-2013 |
20130142840 | DENSE FIBRILLAR COLLAGEN MATRICES FOR TISSUE REPAIR AND THE PREPARATION METHOD THEREOF - Method for preparing a homogeneous collagen-based material by concentration of a collagen solution, includes bringing a collagen solution into contact by way of continuous injection and use of the material for tissue repair. | 06-06-2013 |
20130096660 | IMPLANT HAVING THREE-DIMENSIONAL SHAPE FOR ELECTRICALLY STIMULATING A NERVE STRUCTURE - The invention relates to an implant which includes, in order to electrically stimulate a nerve structure, in particular the retina, an electrically insulating substrate ( | 04-18-2013 |
20130095133 | PHARMACEUTICAL COMPOSITIONS COMPRISING A POLYPEPTIDE COMPRISING AT LEAST ONE CXXC MOTIF AND HETEROLOGOUS ANTIGENS AND USES THEREOF - The invention relates to pharmaceutical compositions using a polypeptide comprising at least one CXXC motif, such as | 04-18-2013 |
20130065948 | NUCLEIC ACID MOLECULES AND METHODS FOR EXCHANGING EXON(S) BY TRANSSPLICING - The present invention provides methods and compositions for generating novel nucleic acid molecules through targeted spliceosome mediated simple or double trans-splicing. The compositions of the invention include pre-trans-splicing molecules (PTMs) designed to interact with a target precursor messenger RNA molecule (target pre-mRNA) and to mediate a simple or double trans-splicing reaction resulting in the generation of a novel chimeric RNA molecule (chimeric RNA). | 03-14-2013 |
20130022068 | Laser System Provided With a Frequency Servo - The invention relates to a laser system provided with a laser radiation device ( | 01-24-2013 |
20130011577 | METHOD FOR PROVIDING A METAL ELECTRODE ON THE SURFACE OF A HYDROPHOBIC MATERIAL - A method of making a metal electrode on the surface of a hydrophobic material ( | 01-10-2013 |
20130000100 | PROCESS FOR MANUFACTURING A FLEXIBLE ELONGATE STRUCTURE HAVING AN ORIENTABLE END - A method of fabricating an elongate structure having a steerable end, the structure including a flexible longitudinal body associated with at least one actuator member having at least one shape memory alloy wire or “SMAW” extending along the body and anchored thereto at its ends, and associated with a mechanism for heating it in controlled manner. The method includes the following steps: inserting at least one of the ends of the SMAW in tubes; crimping the tubes onto the ends of the SMAW; and securing the tubes to the body in such a manner that the wire extends along the body. | 01-03-2013 |
20120285315 | STRING MUSIC INSTRUMENT AND SOUND BOARD - A musical instrument having strings and a soundboard, wherein the soundboard is excited by the strings by a transducer and is associated with differential stiffening mechanism defining at least two zones of the soundboard that present complementary vibratory behaviors. The two zones are separated by a slot extending along a common boundary between the two zones. The transducer extends across the slot so as to be connected to both zones of the soundboard, such that both zones are excited simultaneously when action is taken on one of the strings. | 11-15-2012 |
20120283572 | DEVICE FOR MEASURING THE ACTIVITY OF THE SPINAL CORD OF A VERTEBRA - A measurement device for measuring activity of the spinal cord of a vertebrate, wherein the device includes at least one main probe ( | 11-08-2012 |
20120276577 | Method for Determining the Susceptibility of a Cell Strain to Drugs - The present invention relates to a method for determining the susceptibility of a cell strain to a compound intended for controlling the growth of said cell strain, comprising:
| 11-01-2012 |
20120264616 | LENTIVIRAL-BASED VECTOR AND ITS USE IN DIRECTED EVOLUTION OF GENOMIC REGIONS, GENES AND POLYNUCLEOTIDES - The present invention concerns a method of directing evolution of a target polynucleotide of interest for obtaining variants of this target polynucleotide, as well as a method to generate genetic variability by preparing a cell library. This invention also relates to a method to isolate or to screen variants of a polynucleotide or variants of a protein able to impact the phenotype of a cell or to confer a desired phenotype to target cells, and to identify theses polynucleotide variants or protein variants responsible for this phenotype. | 10-18-2012 |
20120257218 | METHOD FOR LONGITUDINALLY STABILIZING AN OPTICAL CAVITY - A method of stabilizing the distance (L) between two mirrors ( | 10-11-2012 |
20120245220 | NUCLEIC ACID MOLECULES AND METHODS FOR EXCHANGING EXON(S) BY TRANSSPLICING - The present invention provided methods and compositions for generating novel nucleic acid molecules through targeted spliceosome mediated simple or double trans-splicing. The compositions of the invention include pre-trans-splicing molecules (PTMs) designed to interact with a target precursor messenger RNA molecule (target pre-mRNA) and to mediate a simple or double trans-splicing reaction resulting in the generation of a novel chimeric RNA molecule (Chimeric RNA). | 09-27-2012 |
20120232894 | DEVICE FOR RECONSTRUCTING SPEECH BY ULTRASONICALLY PROBING THE VOCAL APPARATUS - The invention provides a portable device for recognizing and/or reconstructing speech by ultrasound probing of the vocal apparatus, the device including at least one ultrasound transducer ( | 09-13-2012 |
20120206177 | DEVICE FOR GENERATING CLOCK SIGNALS FOR ASYMMETRIC COMPARISON OF PHASE ERRORS - A device for generating a clock signal, including a phase-locked loop including: a controlled oscillator to deliver a clock signal; plural phase comparators to compare a phase of the clock signal delivered by the controlled oscillator with plural clock signal phases applied at an input of the phase-locked loop; a mechanism for weighted summation of output signals of the plural phase comparators such that one or more of the weighting coefficients applied to one of the output signals has an absolute value that overrides the absolute values of the other weighting coefficients applied to the other output signals; and a mechanism filtering the weighted sum of the output signals of the plural phase comparators, to deliver at an output a control signal to the controlled oscillator. | 08-16-2012 |
20120141422 | WIDESPREAD GENE DELIVERY TO THE RETINA USING SYSTEMIC ADMINISTRATION OF AAV VECTORS - The present invention relates to compositions and methods, in particular to methods based on systemic administration of scAAV, for delivering genes to cells of the retina of mammals, and in particular to photoreceptor cells, ganglion cells, glial cells, inner nuclear layer cells or cells of the retinal pigmented epithelium. | 06-07-2012 |
20120138154 | MICROFLUIDIC DEVICE FOR CONVEYING A SUBSTANCE BY DIFFUSION IN A POROUS SUBSTRATE - The invention provides a microfluidic device for conveying substance by diffusion in a porous substrate from a substance injection zone to a substance arrival zone, which zones are connected by a substance-channeling zone. According to the invention, the porous substrate presents a free surface that is partially covered by a mask that is impermeable and that extends from the injection zone to the arrival zone in order to define the substance-channeling zone in the substrate so as to enable the substance to evaporate through a non-covered portion of the free surface. | 06-07-2012 |
20120135926 | PEPTIDES FOR INHIBITING IGF-1 - The invention relates to peptides useful for inhibiting IGF-1 activity and their use as agents for inhibition of in vitrocell proliferation and for treatment of various diseases. | 05-31-2012 |
20120131579 | METHOD AND SYSTEM FOR DEPLOYING AT LEAST ONE VIRTUAL NETWORK ON THE FLY AND ON DEMAND - The invention relates to a method for generating, on the fly and on demand, at least one virtual network ( | 05-24-2012 |
20120117246 | Method And System For The Efficient And Automated Management of Virtual Networks - The invention relates to a method for the automated management of the performance of at least one virtual network ( | 05-10-2012 |
20120115510 | GEOLOCATION OF A MOBILE STATION OF A WIRELESS TELEPHONY NETWORK - The disclosure relates to a method for locating a mobile station inside an area covered by a wireless telephony cellular network in which the mobile station operates. The method includes using the mobile station to measure the received power on at least seven different communication channels of the network (step | 05-10-2012 |
20120095082 | USE OF INTERFERING RNA FOR TREATING AN HIV INFECTION - The present invention relates to interfering RNAs, in particular miRNAs, capable of specifically blocking the replication of a strain of the HIV virus that is resistant to an antiretroviral compound, and use thereof for treating infections by this type of virus. | 04-19-2012 |
20120022696 | DEVICE FOR CONTROLLING THE MOVEMENT OF A SURGICAL INSTRUMENT - A control device includes an arm ( | 01-26-2012 |
20120001572 | DEVICE FOR QUICKLY GENERATING A TORQUE ON AN EXTENDED DYNAMIC RANGE WITH LOW INERTIA - The invention relates to a device for generating a torque on an output member in response to a torque setpoint, including a first motor unit including at least one motor of a first power, or small motor, having a shaft to which the output member is connected, a second motor unit including at least one motor of a second power higher than the first power, or large motor, having a shaft rotationally connected to the output member via viscous coupling means, and servo-control means programmed, in response to a torque setpoint (M | 01-05-2012 |
20110310919 | Laser System Provided With a Frequency Servo - The invention relates to a laser system provided with a laser radiation device ( | 12-22-2011 |
20110306041 | DEVICE FOR CELL CULTURE - A device for cell culture, in particular of neuronal cells, including: a substrate defining a first microfluidic chamber to be seeded with a first cell culture, and at least a second microfluidic chamber, a fluidic interconnection system connecting the first and second chambers and enabling cellular extensions, in particular axons, to extend from one chamber to the other, wherein the interconnection system of the device is made so as to promote the progression of at least one first type of cellular extension, the first and second types of extension being different either due to the microfluidic chamber from which they originate, or due to the type of cell of which they constitute an extension. | 12-15-2011 |
20110230122 | NANOSCALE CUBIC BORON NITRIDE - The invention relates to a method of manufacturing nanoscale cubic boron nitride and to the nanoscale cubic boron nitride thus obtained. The method according to the invention of manufacturing nanoscale boron nitride of cubic structure is characterized in that it comprises the following steps: a) compression of a pyrolytic boron nitride powder having a structure of the monomodal turbostratic graphite type at a pressure of between 19 and 21 GPa and at room temperature; and b) heating of the powder under a pressure of between 19 and 21 GPa and at a temperature of between 1447° C. (1720 K) and 1547° C. (1820 K) for less than 2 minutes. The invention is applicable in particular in the field of abrasives. | 09-22-2011 |
20110188717 | METHOD AND DEVICE FOR READING AN EMULSION - A method for reading an emulsion ( | 08-04-2011 |
20110166282 | METHOD FOR PREPARING A POLYMER PARTICLE DISPERSION IN AN AQUEOUS MEDIUM - The invention relates to a process for the preparation of an aqueous dispersion of polymer particles in an aqueous medium employing a living macroinitiator requiring a reinitiation temperature of less than 100° C. | 07-07-2011 |
20110124723 | Compounds for Preventing and Treating Plasmodium Infections - The present invention relates to the use of at least one compound of formula (I) for the manufacture of a medicament intended for preventing or treating infections by a | 05-26-2011 |
20110083730 | DERIVATIVES OR DIPYRANNYLIDENE TYPE AS ANODE INTERFACE LAYER IN ELECTRONIC DEVICES - The present invention relates to substrates coated with films comprising compounds of general formula (I) below: | 04-14-2011 |
20110046220 | PARABEN COMPOUNDS - The invention relates to a | 02-24-2011 |
20100322913 | CHIMERIC POLYPEPTIDE COMPRISING THE FRAGMENT B OF SHIGA TOXIN AND PEPTIDES OF THERAPEUTIC INTEREST - The invention pertains to methods for using chimeric polypeptides of the formula: | 12-23-2010 |
20100285099 | VACCINATION BY TRANSCUTANEOUS TARGETING - The present invention relates to a method of vaccination via hair follicles that makes it possible to target vaccine components to the antigen-presenting cells in order to induce a protective and effective immune response against pathogens. | 11-11-2010 |
20100284932 | FLUORESCENT EMULSIONS FOR OPTICAL IMAGING - The invention relates to a fluorescent emulsion, to a diagnostic reagent containing the same, and to the use thereof in the preparation of a diagnostic reagent for in vivo fluorescence imaging. | 11-11-2010 |
20100236706 | METHOD OF FASTENING LAMELLAE OF A LAMELLAR MATERIAL ON A SUITABLE SUBSTRATE - The invention provides a method of fastening lamellae of a lamellar material that is at least partially conductive onto an insulating substrate ( | 09-23-2010 |
20100233144 | METHOD FOR OPTIMIZING BLOOD CELL TRANSPLANTS - The invention relates to the use of allogenic T lymphocytes for the preparation of a composition intended to be injected into a recipient patient as a conditioning for a transplantation of haematopoietic stem cells, said allogenic T lymphocytes expressing a molecule allowing their specific destruction. | 09-16-2010 |
20100215629 | TREATMENT OF TUMORS USING T LYMPHOCYTE PREPARATIONS - The invention relates to the treatment of a tumor in a patient, by injecting T lymphocytes depleted of regulatory T lymphocytes, and expressing a molecule allowing their specific destruction, the patient receiving beforehand a non-myeloablative or myeloablative lymphopenic treatment. | 08-26-2010 |
20100209902 | Use of a Globin, a Globin Protomer or an Extracellular Hemoglobin for the Preservation of Organs, Tissues, Organ and Tissue Cells and Cell Cultures - The invention relates to the use of at least one globin and/or at least one globin protomer and/or at least one naturally extracellular native hemoglobin for the preservation of organs, tissues, organ and tissue cells and cell cultures. | 08-19-2010 |
20100184790 | PYRROLO[2,3-B]PYRIDINE COMPOUNDS, AZAINDOLE COMPOUNDS USED FOR SYNTHESIZING SAID PYRROLO[2,3-B]PYRIDINE COMPOUNDS, METHODS FOR THE PRODUCTION THEREOF, AND USES THEREOF - The invention relates to pyrrolo[2,3-b]pyridine compounds and azaindole compounds used for the synthesis thereof. The invention also relates to methods for the production thereof and the uses thereof. Said novel pyrrolo[2,3-b]pyridine compounds according to the invention have great antiproliferative, apoptotic, and neuroprotective activities. The invention particularly applies to the pharmaceutical field. | 07-22-2010 |
20090194639 | SPACECRAFT AND METHOD FOR OPERATING THE SPACECRAFT - The present invention relates to a spacecraft (P) comprising a propulsion system ( | 08-06-2009 |
20090091090 | HYDRAULIC SYSTEM - The present invention relates to a hydraulic system that includes a compression chamber capable of being subjected to the pressure of a hydraulic fluid; a piston movable inside the compression chamber along an axis; and at least one sealing gasket disposed between the piston and a wall of the compression chamber, the gasket occupying an axial position that varies circumferentially around the axis in such a manner as to compensate for non-axially symmetrical stresses induced by the pressure of the fluid. | 04-09-2009 |