Board of Regents of the University of Nebraska Patent applications |
Patent application number | Title | Published |
20160115124 | SMALL MOLECULE RNASE INHIBITORS AND METHODS OF USE - Small molecule inhibitors of bacterial ribonuclease (e.g., RnpA) and methods for their synthesis and use are described herein. The methods of using the compounds include treating and preventing microbial infections and inhibiting bacterial ribonuclease. Also described herein are methods of identifying compounds for treating or preventing a microbial infection. | 04-28-2016 |
20160022374 | ON-BOARD TOOL TRACKING SYSTEM AND METHODS OF COMPUTER ASSISTED SURGERY - A number of improvements are provided relating to computer aided surgery utilizing an on tool tracking system. The various improvements relate generally to both the methods used during computer aided surgery and the devices used during such procedures. Other improvements relate to the structure of the tools used during a procedure and how the tools can be controlled using the OTT device. Still other improvements relate to methods of providing feedback during a procedure to improve either the efficiency or quality, or both, for a procedure including the rate of and type of data processed depending upon a CAS mode. | 01-28-2016 |
20150283118 | SMALL MOLECULE RNASE INHIBITORS AND METHODS OF USE - Small molecule inhibitors of bacterial ribonuclease (e.g., RnpA) and methods for their synthesis and use are described herein. The methods of using the compounds include treating and preventing microbial infections and inhibiting bacterial ribonuclease. | 10-08-2015 |
20150190170 | Methods, Systems and Devices for Surgical Access and Insertion - The various embodiments herein relate to systems, devices, and/or methods relating to surgical procedures, and more specifically for accessing an insufflated cavity of a patient and/or positioning surgical systems or devices into the cavity. | 07-09-2015 |
20150182358 | STENT TO ASSIST IN ARTERIOVENOUS FISTULA FORMATION - There is described an arteriovenous fistula stent, having a tubular body comprising a series of sinusoidal shaped struts along the length of the tubular body. A plurality of curvilinear connectors extend between and are attached to adjacent struts wherein a first end of a connector is attached to a distal face of a proximal strut apex and a second end of a connector is attached to a proximal face of a distal strut apex. A pair of unconnected strut apexes are between pairs of connected apexes. When the tubular body is in a stowed configuration a proximal aperture and a distal aperture are circular and when the tubular body is in a deployed configuration the distal aperture is oblong or ovoid. There is also described a method for inserting a stent for use in creation of an arteriovenous fistula by identifying a candidate artery and a candidate vein and dissecting the candidate vein. Next, inserting a stent into the vein and creating a breach in the candidate artery at a desired angle and location. Next, introducing the stent and vein into the candidate artery and forming the stent into a curvature angle selected to minimize turbulent blood flow in an anastomosis formed by the vein and the artery. Optionally, there is a step of fastening a distal portion of the stent to the artery. | 07-02-2015 |
20150132297 | SURVIVAL PREDICTOR FOR DIFFUSE LARGE B CELL LYMPHOMA - The invention provides methods and materials related to a gene expression-based survival predictor for DLBCL patients. | 05-14-2015 |
20150112242 | SHEATH - The present application includes a sheath that is suitable for use in a variety of medical procedures. In one or more implementations, the sheath includes a shunt member, and a curvable portion. The curvable portion may be configured in various orientations to facilitate an intervention, such as a hemodialysis intervention, or the like, by an operator. The curvable portion may be configured to bend between a substantially straight configuration and a curved configuration. In implementations, the sheath may be configured to have detachable and/or interchangeable components (e.g., shunt member, curvable portion, etc.). | 04-23-2015 |
20150080460 | Methods for Administration and Methods for Treating Cardiovascular Diseases with Resiniferatoxin - There is disclosed a method for administration of a formulation of resiniferatoxin (RTX) to provide cardiac sympathetic afferent denervation when applied in an amount and concentration sufficient to chemically denervate vanilloid 1 receptor (TRPV1)-expressing CSAR (cardiac sympathetic afferent reflex) afferents. There is further disclosed a method for treating heart failure or hypertension and its related indications selected from the group consisting of increased sympatho-excitation, cardiac hypertrophy, increased left ventricular end diastolic pressure (LVEDP), lung edema, and combinations thereof, comprising administering an effective amount of RTX directly to a tissue site selected from the group consisting of epicardium, a T1-T4 dorsal root ganglion and intrathecally to the T1-T4 region of the spinal column. | 03-19-2015 |
20150079007 | TUNABLE MULTIMODAL NANOPARTICLES AND METHODS OF USE THEREOF - Tunable nanoparticles and methods of use thereof are provided. In accordance with the instant invention, tunable nanoparticles comprising a metal nanoparticle core (e.g., a paramagnetic particle (e.g., USPIO) or a quantum dot) and a polymer linked to a metal binding moiety are provided. The polymer of the nanoparticle is bound to the metal nanoparticle core by the metal binding moiety and coats the metal nanoparticle core. In a particular embodiment, the metal binding moiety comprises bisphosphonate, pyrophosphate, or a derivative thereof. In a particular embodiment, the polymer is a hydrophilic polymer, an amphiphilic block copolymer or an ionic block copolymer. | 03-19-2015 |
20140371762 | Methods, Systems, and Devices Relating to Force Control Surgical Systems - The various embodiments herein relate to robotic surgical systems and devices that use force and/or torque sensors to measure forces applied at various components of the system or device. Certain implementations include robotic surgical devices having one or more force/torque sensors that detect or measure one or more forces applied at or on one or more arms. Other embodiments relate to systems having a robotic surgical device that has one or more sensors and an external controller that has one or more motors such that the sensors transmit information that is used at the controller to actuate the motors to provide haptic feedback to a user. | 12-18-2014 |
20140329714 | STAT3 ACTIVATION AS A MARKER FOR CLASSIFICATION AND PROGNOSIS OF DLBCL PATIENTS - Methods are disclosed for determining classification and prognosis of patients with diffuse large B-cell lymphoma (DLBCL) using activation of signal transducer and activator of transcription 3 (STAT3). | 11-06-2014 |
20140303434 | Robotic Surgical Devices, Systems, and Related Methods - The embodiments disclosed herein relate to various medical device components, including components that can be incorporated into robotic and/or in vivo medical devices. Certain embodiments include various modular medical devices for in vivo medical procedures. | 10-09-2014 |
20140276944 | Methods, Systems, and Devices Relating to Robotic Surgical Devices, End Effectors, and Controllers - The various embodiments disclosed herein relate to improved robotic surgical systems, including robotic surgical devices having improved arm components and/or biometric sensors, contact detection systems for robotic surgical devices, gross positioning systems and devices for use in robotic surgical systems, and improved external controllers and consoles. | 09-18-2014 |
20140257335 | Multifunctional Operational Component for Robotic Devices - The various embodiments disclosed herein relate to modular medical devices, including various devices with detachable modular components and various devices with pivotally attached modular components. Additional embodiments relate to procedures in which various of the devices are used cooperatively. Certain embodiments of the medical devices are robotic in vivo devices. | 09-11-2014 |
20140199242 | COMPOSITIONS AND METHODS FOR DETECTION AND TREATMENT OF CANCER - Novel antibodies for the detection and/or treatment of a cancer (e.g., a pancreatic cancer or an ovarian cancer) are provided. In certain embodiments the antibodies bind a region of the MUC4 protein that does not comprise the central tandem repeat (TR) domain of MUC4. Certain antibodies bind to the MUC4 peptide fragment MUC4-α-N-Ter and/or to the MUC4 peptide fragment MUC4-α-C-Ter. Chimeric constructs comprising such antibodies are also provided. | 07-17-2014 |
20140170068 | BIOMARKER FOR CORONARY ARTERY DISEASE - In various embodiments methods are provided for identifying a mammal having an elevated risk for an adverse cardiac event (e.g. an MI) and/or determining the prognosis for the mammal. In certain embodiments the methods comprise determining, or causing to be determined, the presence and/or level of antibodies that bind a malondialdehyde-acetaldehyde adduct (MAA adduct) in a biological sample from the mammal, where an elevated level of anti-MAA adduct antibodies, as compared to the level found in a normal healthy mammal is an indicator that that said mammal has one or more atherosclerotic lesions and/or is at elevated risk for a myocardial infarction. | 06-19-2014 |
20140157452 | Plants with Useful Traits and Related Methods - The present invention provides methods for obtaining plants that exhibit useful traits by transient suppression of the MSH1 gene of the plants. Methods for identifying genetic loci that provide for useful traits in plants and plants produced with those loci are also provided. In addition, plants that exhibit the useful traits, parts of the plants including seeds, and products of the plants are provided as well as methods of using the plants. | 06-05-2014 |
20140152814 | System for Imaging and Measuring Rail Deflection - Devices, systems, and methods for imaging and measuring deflections in structures such as railroad rail are disclosed. One exemplary embodiment relates to a vision system having a high-speed, visible-light imaging camera and an evaluation unit configured for analyzing images from the camera to detect geometric variations in the structure. In a second example, additional sensors are used to identify the wheel location(s) in the same reference frame as the measurement system. In analyzing structures such as railroad track rail, the imaging camera can be coupled to a moving rail vehicle and configured for generating images of the rail as the vehicle moves along the track. | 06-05-2014 |
20140123761 | Systems and Methods to Determine and Monitor Changes in Rail Conditions - The embodiments disclosed herein relate to various systems and methods for determining the residual stress in polycrystalline materials. | 05-08-2014 |
20140121166 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF JUVENILE NEURONAL CEROID LIPOFUSCINOSIS AND RELATED DISORDERS - Provided are materials and methods for the prevention and treatment of Juvenile Neuronal Ceroid Lipofuscinosis comprising administration of an effective amount of at least one of a hemi-channel inhibitor or a phosphodiesterase-4 inhibitor. In some embodiments, the methods comprise administration of an effective amount of each of a hemi-channel inhibitor and a phosphodiesterase-4 inhibitor. Also provided are pharmaceutical compositions comprising a hemi-channel inhibitor or a phosphodiesterase-4 inhibitor, as well as kits comprising at least one effective dose of a hemi-channel inhibitor or a phosphodiesterase-4 inhibitor or a combination of both. | 05-01-2014 |
20140120075 | Nanozyme Compositions and Methods of Synthesis and Use Thereof - Nanozymes and methods of use and synthesis thereof are provided. | 05-01-2014 |
20140066955 | Robotic Devices with Arms and Related Methods - Various robotic devices and related medical procedures are disclosed herein. Each of the various robotic devices has an arm. The arm can have two arm components coupled at a joint. | 03-06-2014 |
20140058205 | Methods, Systems, and Devices for Surgical Access and Insertion - The various embodiments herein relate to systems, devices, and/or methods relating to surgical procedures, and more specifically for accessing an insufflated cavity of a patient and/or positioning surgical systems or devices into the cavity. | 02-27-2014 |
20140054442 | Nanocomposite Photodetector - A photodetector includes an anode that is transparent or partially transparent to light, a cathode and an active layer disposed between the anode and the cathode. The active layer includes a nanocomposite material that has a polymer blended with nanoparticles or organic electron trapping particles. The photodetector has a low dark current when not illuminated by light and has a high conductivity when illuminated by light, in which the light passes the anode and is absorbed by the active layer. | 02-27-2014 |
20140052387 | System and Methods for Determining Structure Stiffness - Systems and methods for determining the stiffness of a structure based on vertical track modulus are disclosed in accordance with embodiments of the present invention. Vertical deflection data is collected along a particular section of a structure, such as a railroad track. A first set of vertical modulus is determined, based in part, on the collected vertical deflection data. At a second time, vertical deflection data is again collected along the particular section of the structure to be used in determining a second set of vertical modulus. At least the first and second sets of vertical modulus are analyzed to determine a mathematical algorithm that facilitates developing a trend in the vertical track modulus of the structure and evaluating the stiffness of the structure. | 02-20-2014 |
20140050728 | METHODS AND COMPOSITIONS FOR INHIBITING CYCLOPHILIN D FOR THE TREATMENT AND PREVENTION OF OBESITY AND KIDNEY INDICATIONS - Methods and compositions for modulating cyclophilin D, e.g., at least one cyclophilin D biological activity, are provided. Modulation of cyclophilin D is useful in preventing or treating obesity, an overweight condition, or in accommodating a desire to lose weight as well as being useful in treating a variety of kidney diseases. | 02-20-2014 |
20140039515 | Single Site Robotic Device and Related Systems and Methods - The embodiments disclosed herein relate to various medical device components, including components that can be incorporated into robotic and/or in vivo medical devices. Certain embodiments include various medical devices for in vivo medical procedures. | 02-06-2014 |
20140039068 | Drug Delivery Compositions and Methods - The present invention provides compositions and methods for the delivery of therapeutics to a cell or subject. | 02-06-2014 |
20140017330 | Activated Nucleoside Analog Conjugates and Methods of Use Thereof - The present invention provides nanogel formulations and methods of use thereof. | 01-16-2014 |
20130345717 | Local Control Robotic Surgical Devices and Related Methods - The various embodiments disclosed herein relate to various robotic medical devices, including robotic devices that are disposed within a body cavity and positioned using a support component disposed through an orifice or opening in the body cavity. Additional embodiments relate to devices having arms coupled to a device body wherein the device has a minimal profile such that the device can be easily inserted through smaller incisions in comparison to other devices without such a small profile. Further embodiments relate to methods of operating the above devices. | 12-26-2013 |
20130324964 | HEMODIALYSIS CATHETER WITH DISPLACEABLE LUMENS TO DISRUPT A FIBROUS SHEET - A hemodialysis catheter with an integrated means of displacing away from each other portions of a distal end of a tube assembly. The displacement serves to allow a fibrous sheath to be disrupted without removing the catheter from a patient. | 12-05-2013 |
20130303585 | SMALL MOLECULE RNASE INHIBITORS AND METHODS OF USE - Small molecule inhibitors of bacterial ribonuclease (e.g., RnpA) and methods for their synthesis and use are described herein. The methods of using the compounds include treating and preventing microbial infections and inhibiting bacterial ribonuclease. Also described herein are methods of identifying compounds for treating or preventing a microbial infection. | 11-14-2013 |
20130296386 | SMALL MOLECULE RNASE INHIBITORS AND METHODS OF USE - Small molecule inhibitors of bacterial ribonuclease (e.g., RnpA) and methods for their synthesis and use are described herein. The methods of using the compounds include treating and preventing microbial infections and inhibiting bacterial ribonuclease. | 11-07-2013 |
20130289041 | QUINOXALINE COMPOUNDS AND USES THEREOF - Disclosed herein are compounds of formula (I) and methods of inhibiting IKKβ and the NF-κB signaling and mTOR pathways. | 10-31-2013 |
20130243847 | ACTIVATED CREATININE AND PRECURSORS THEREOF AS ANTIBACTERIAL AGENTS, COMPOSITIONS AND PRODUCTS CONTAINING SUCH AGENTS AND USE THEREOF - Creatinine, creatinine precursors or the pharmaceutically acceptable salts thereof are activated to function as an antibacterial agent which has broad spectrum activity and is beneficially used in a variety of applications, such as antimicrobial wound dressings, compositions for topical delivery of the antibacterial agent and for preventing and/or inhibiting the occurrence or spread of bacterial infection, as well as the growth of odor-causing bacteria, to name a few. | 09-19-2013 |
20130243696 | Compositions and Methods for the Treatment of Traumatic Brain Injury - Compositions and methods for the inhibition and/or prevention of traumatic brain injury and the symptoms associated with it are provided. | 09-19-2013 |
20130236553 | Compositions and Methods for the Delivery of Therapeutics - The present invention provides compositions and methods for the delivery of therapeutics to a cell or subject. | 09-12-2013 |
20130195964 | Compositions and Methods for the Treatment of Cancer - The present invention provides compositions and methods for the treatment of cancer are provided. | 08-01-2013 |
20130178867 | Robotic Surgical Devices, Systems, and Related Methods - The embodiments disclosed herein relate to various medical device components, including components that can be incorporated into robotic and/or in vivo medical devices. Certain embodiments include various modular medical devices for in vivo medical procedures. | 07-11-2013 |
20130161596 | PHOTOVOLTAIC DEVICE - An apparatus includes a substrate; and a photoactive layer disposed on the substrate. The photoactive layer includes an electron acceptor material; an electron donor material; and a material having dipoles. | 06-27-2013 |
20130123336 | Polyplexes of Hydrophobically-Modified siRNA for Delivery of siRNA - The present invention provides compositions and methods for delivering nucleic acid molecules to a cell. | 05-16-2013 |
20130119346 | IRON PYRITE NANOCRYSTALS - An apparatus includes a nanocrystal. The nanocrystal includes a core including FeS | 05-16-2013 |
20130072598 | Thermoplastics from Distillers Dried Grains and Feathers - A thermoplastic biobased material-containing composition comprising chemically-modified feathers and/or dried distillers grains and a process for forming the thermoplastic biobased material-containing composition. More specifically, the thermoplastic biobased material-containing composition comprises one or more of the following chemically-modified biobased materials: (a) acylated biobased material having a % Acyl Content that is at least 3% and a % Weight Gain that is at least 1%, and; (b) etherified biobased material having a % Weight Gain that is at least 2%; and (c) graft polymerized biobased material having a % Monomer Conversion that is at least 40%, a % Grafting Efficiency that is at least 30%, and a % Grafting that is at least 10%. | 03-21-2013 |
20130052154 | Compositions and Methods for the Treatment of Lung Inflammation - Compositions and methods for the treatment of inflammation are provided. | 02-28-2013 |
20130041360 | Methods, Systems, and Devices Relating to Surgical End Effectors - The embodiments disclosed herein relate to various medical device components, including components that can be incorporated into robotic and/or in vivo medical devices, and more specifically including end effectors that can be incorporated into such devices. Certain end effector embodiments include various vessel cautery devices that have rotational movement as well as cautery and cutting functions while maintaining a relatively compact structure. Other end effector embodiments include various dual end effector devices that have more than one end effector. | 02-14-2013 |
20130017166 | Protein-Poly(2-oxazoline) Conjugates for Enhanced Cellular Delivery and Transport Across Biological Barriers - The present invention provides polymer conjugates and methods of use thereof. | 01-17-2013 |
20120309652 | Restricted Access Media and Methods for Making Restricted Access Media - The present invention is directed to restricted access media (RAM), methods for preparing restricted access media, and kits for preparing restricted access media that contain protected ligand binding agents or protected enzymes. Certain RAM provided contain a plurality of protected regions of the support that contain ligand binding agents that are protected by blocking agents. Certain RAM provided contain a plurality of protected regions of the support that contain unbound ligand binding agents or enzymes that are retained in the protected regions by a capping agent. Methods of making the RAM of the invention and associated kits are also provided | 12-06-2012 |
20120300060 | VISION SYSTEM FOR IMAGING AND MEASURING RAIL DEFLECTION - Devices, systems, and methods for imaging and measuring deflections in structures such as railroad rail are disclosed. An example vision system comprises a high-speed, visible-light imaging camera and an evaluation unit configured for analyzing images from the camera to detect geometric variations in the structure. In analyzing structures such as railroad track rail, the imaging camera can be coupled to a moving rail vehicle and configured for generating images of the rail as the vehicle moves along the track. | 11-29-2012 |
20120284814 | Plants With Useful Traits and Related Methods - The present invention provides methods for obtaining plants that exhibit useful traits by transient suppression of the MSH1 gene of the plants. Methods for identifying genetic loci that provide for useful traits in plants and plants produced with those loci are also provided. In addition, plants that exhibit the useful traits, parts of the plants including seeds, and products of the plants are provided as well as methods of using the plants. | 11-08-2012 |
20120246864 | PAVEMENT CRACK CLEANER - Devices for cleaning and preparing pavement cracks for sealing are disclosed. An example device comprises a wire brush assembly for removal of mid and large-sized debris, an air blaster for removal of fine-grained particulate, a heat lance, and a vacuum for controlled removal of debris and particulates. The example device would also have means for attachment to an air compressor. | 10-04-2012 |
20120225793 | METHODS FOR IDENTIFYING, DIAGNOSING, AND PREDICTING SURVIVAL OF LYMPHOMAS - Gene expression data provides a basis for more accurate identification and diagnosis of lymphoproliferative disorders. In addition, gene expression data can be used to develop more accurate predictors of survival. The present invention discloses methods for identifying, diagnosing, and predicting survival in a lymphoma or lymphoproliferative disorder on the basis of gene expression patterns. The invention discloses a novel microarray, the Lymph Dx microarray, for obtaining gene expression data from a lymphoma sample. The invention also discloses a variety of methods for utilizing lymphoma gene expression data to determine the identity of a particular lymphoma and to predict survival in a subject diagnosed with a particular lymphoma. This information will be useful in developing the therapeutic approach to be used with a particular subject. | 09-06-2012 |
20120132005 | SYSTEMS AND METHODS FOR ULTRASONICALLY EVALUATING STRUCTURAL PROPERTIES - Systems and methods for ultrasonically evaluating one or more microstructural material properties of a structural specimen are disclosed. An example system comprises an ultrasonic sensor unit including a plurality of ultrasonic transducers that generate ultrasonic backscatter within the specimen, and an evaluation module that performs an autocorrelation function on the ultrasonic backscatter data. An autocorrelation algorithm is configured to execute a single scattering response (SSR) model that computes second order grain statistics of the structural specimen. | 05-31-2012 |
20120118368 | Method for Increasing the Efficiency of Organic Photovoltaic Cells - The present invention is directed to an organic photovoltaic cell that contains one or more dipole regions generally disposed between an organic active region and the electrodes and a process for producing such an organic photovoltaic cell. | 05-17-2012 |
20120035582 | METHODS AND SYSTEMS FOR HANDLING OR DELIVERING MATERIALS FOR NATURAL ORIFICE SURGERY - The embodiments disclosed herein relate to various medical systems, including systems that can be used in conjunction with medical devices used in endoscopic surgery. Certain embodiments include various material handling devices that can transport materials between the inside and the outside of an endoscopic surgery patient. | 02-09-2012 |
20110268691 | dsRNA Delivery Composition and Methods of Use - The present invention provides for compositions comprising a cucurbitacin bait for stimulating insect feeding and a dsRNA—such as for eliciting RNAi mediated gene silencing in an insect. The present invention also provides for methods of delivering a dsRNA molecule to an insect, inhibiting protein expression in an insect, and killing an insect by providing a dsRNA molecule. | 11-03-2011 |
20110237890 | MODULAR AND COOPERATIVE MEDICAL DEVICES AND RELATED SYSTEMS AND METHODS - The various embodiments disclosed herein relate to modular medical devices, including various devices with detachable modular components and various devices with pivotally attached modular components. Additional embodiments relate to procedures in which various of the devices are used cooperatively. Certain embodiments of the medical devices are robotic in vivo devices. | 09-29-2011 |
20110195064 | SURVIVAL PREDICTOR FOR DIFFUSE LARGE B CELL LYMPHOMA - The invention provides methods and materials related to a gene expression-based survival predictor for diffuse large B cell lymphoma (DLBCL) patients. | 08-11-2011 |
20110098942 | SYSTEM AND METHODS TO DETERMINE AND MONITOR CHANGES IN MICROSTRUCTURAL PROPERTIES - A system and methods with which changes in microstructure properties such as grain size, grain elongation, texture, and porosity of materials can be determined and monitored over time to assess conditions such as stress and defects. An example system includes a number of ultrasonic transducers configured to transmit ultrasonic waves towards a target region on a specimen, a voltage source configured to excite the first and second ultrasonic transducers, and a processor configured to determine one or more properties of the specimen. | 04-28-2011 |
20110086742 | REHABILITATION AND EXERCISE MACHINE - An improved rehabilitation and exercise machine is provided which allows a person with physical limitations, disabilities or chronic conditions to use the machine in order to rehabilitate their muscles, improve joint flexibility, and enhance cardiovascular fitness. | 04-14-2011 |
20110001966 | REMOTE CHEMICAL AND ELEMENTAL ANALYSIS BY ULTRA FAST SPECTROSCOPY - Systems and methods are provided for monitoring materials using ultra fast laser pulses. Ultra fast laser pulses, such as femtosecond or attosecond laser pulses, are applied to the materials and laser pulses that result from interactions between the ultra fast laser pulses and the materials are collected. Spectral content of the resulting pulses is generated and presented. The elemental composition of the materials is determined using the spectral content. | 01-06-2011 |
20100318059 | ROBOTIC DEVICES WITH AGENT DELIVERY COMPONENTS AND RELATED METHODS - Various robotic devices and related medical procedures are disclosed herein. Each of the various robotic devices have an agent delivery component. The devices include mobile robotic devices and fixed base robotic devices as disclosed herein. The agent delivery component can have at least one agent reservoir and a discharge component in fluidic communication with the at least one reservoir. | 12-16-2010 |
20100212044 | Pearl millet line 53-1-1 with PP3 gene and all derivatives produced by any method - The invention relates to a pearl millet plant, seed, variety, parental line and hybrid. More specifically the invention relates to a pearl millet plant having a mutant allele that increases purple pigmentation in many plant parts. The invention relates to crossing inbreds, varieties, and hybrids containing the purple allele to produce novel types and hybrids of pearl millet and other compatible millet species, both for pigment extraction and ornamental purposes. | 08-19-2010 |
20100121152 | SUCTION CATHETER ASSEMBLY FOR A LARYNGOSCOPE - A laryngoscope is provided with a suction catheter assembly that includes a catheter to supply suction for removal of fluids (e.g., blood, vomit, secretions, and so on) proximate to the distal end of the blade of the laryngoscope during intubation. A connector secures the catheter to the distal end of the blade. A retainer holds the catheter against the side of the blade. | 05-13-2010 |
20100055667 | Restricted Access Media and Methods for Making Restricted Access Media - The present invention is directed to restricted access media (RAM), methods for preparing restricted access media, and kits for preparing restricted access media that contain protected ligand binding agents or protected enzymes. Certain RAM provided contain a plurality of protected regions of the support that contain ligand binding agents that are protected by blocking agents. Certain RAM provided contain a plurality of protected regions of the support that contain unbound ligand binding agents or enzymes that are retained in the protected regions by a capping agent. Methods of making the RAM of the invention and associated kits are also provided | 03-04-2010 |
20090316157 | DIRECT DETECTION OF LOCALIZED MODULATION OF ION CONCENTRATION ON AN ELECTRODE-ELECTROLYTE INTERFACE - The present invention directly measures localized electrochemical processes on a planar electrode using differential interferometry. The ionic charge accumulation at the electrode-electrolyte interface may be directly measured by using differential interferometry as a function of magnitude and frequency (for example, 2-50 kHz) of an external potential applied on an electrode. Methods in accordance with the present invention probe the ion dynamics confined to the electrical double layer. An electric field is applied using a pure AC potential and a superposition of AC and DC-ramp potential to measure ion concentration and detect redox processes. | 12-24-2009 |
20090286149 | ADAPTIVE RECONFIGURABLE BATTERY - Embodiments of the present invention relate to methods and apparatus for a dynamic reconfigurable battery system for supporting power-aware computing. The present invention allows each cell of a multi-cell battery to be charged and/or discharged separately depending on an external load that is applied to the system. The present invention, the dynamic reconfigurable multi-cell battery system, may support dynamic voltage scaling (DVS) by providing fine-tuned voltage levels to satisfy the various power requirements imposed by different system components. Another embodiment of the present invention includes taking advantage of power requirement diversity in a power-aware computing platform to fully utilize a battery's capacity. Also, this system is adaptable to isolate fully discharged or failed cells from other functioning cells. The dynamic reconfigurable design of the present invention provides a solution for an emergent power supply for mission-critical tasks. | 11-19-2009 |
20090274765 | Compositions and Methods for Drug Delivery - The present disclosure is directed to surface-modified particles and to methods of making and using the same. The surface-modified particles comprise a particle core and a coating associated with the particle core, wherein the particle core comprises an active agent, the coating comprises an opsonin, and the surface-modified particle has an average size from about 1 nm to about 2,000 nm. | 11-05-2009 |
20090181449 | DEVICE AND METHOD FOR AUTOMATING MICROBIOLOGY PROCESSES - A device and method for automating the handling and testing of microbiological specimens are provided. A portable specimen collection vehicle (SCV) is provided which comprises a protective housing, a specimen chamber for receiving a biospecimen sample, a plurality of culturing chambers each for receiving a portion of the biospecimen sample and each containing a different culture medium, a system of fluid ducts connecting the specimen chamber to each of the culturing chambers, and an actuator that facilitates flow of portions of the biospecimen sample from the specimen chamber through the system of fluid ducts and into each of the culturing chambers, wherein biological organisms in the biospecimen begin to grow in one or more of the culturing chambers and cultured portions of the biospecimen sample can be withdrawn selectively from the apparatus. A microbiology automation platform includes a computer system that integrates microbiology laboratory instruments and workflow logic in order to perform organism detection and susceptibilities on specimens contained in an SCV. The platform is intended to automate the work of a medical technologist which is characteristically labor intensive. The work performed by the platform includes accession of the specimen, pre-test processes, detection and susceptibility assays, post-test handling and reporting of results. | 07-16-2009 |
20090087494 | Methods and Compositions for Targeted Delivery of Therapeutic Agents - Compositions and methods for targeted delivery of therapeutic agents, and particularly for mucosal, oral, nasal, or parenteral delivery of therapeutic agents. The compositions comprise carrier particles containing or encapsulating a therapeutic agent or agents, which have been modified on their surface to contain one or more targeting moieties that enable the enhanced uptake and transport of the therapeutic agent via receptor-mediated processes such as endocytosis or transcytosis. | 04-02-2009 |
20090076536 | MEDICAL INFLATION, ATTACHMENT, AND DELIVERY DEVICES AND RELATED METHODS - The various embodiments disclosed herein relate to procedural space maintenance devices, medical device positioning devices, and devices that provide both procedural space maintenance and device positioning. Further embodiments relate to medical device insertion and/or retraction devices. | 03-19-2009 |
20090069821 | ROBOTIC DEVICES WITH AGENT DELIVERY COMPONENTS AND RELATED METHODS - Various robotic devices and related medical procedures are disclosed herein. Each of the various robotic devices have an agent delivery component. The devices include mobile robotic devices and fixed base robotic devices as disclosed herein. The agent delivery component can have at least one agent reservoir and a discharge component in fluidic communication with the at least one reservoir. | 03-12-2009 |
20090069542 | Process Of Extracting High Quality Proteins From Cereal Grains And Their ByProducts Using Acidic Medium And A Reducing Agent - The present invention is directed to a method for processing a plant-based protein source, the method comprising an acidic extracting solution comprising a reducing agent is useful for extracting and isolating proteins from plant-based protein sources. | 03-12-2009 |
20090054909 | METHODS AND SYSTEMS OF ACTUATION IN ROBOTIC DEVICES - The embodiments disclosed herein relate to various medical device components, including components that can be incorporated into robotic and/or in vivo medical devices. Certain embodiments include various actuation system embodiments, including fluid actuation systems, drive train actuation systems, and motorless actuation systems. Additional embodiments include a reversibly lockable tube that can provide access for a medical device to a patient's cavity and further provides a reversible rigidity or stability during operation of the device. Further embodiments include various operational components for medical devices, including medical device arm mechanisms that have both axial and rotational movement while maintaining a relatively compact structure. medical device winch components, medical device biopsy/stapler/clamp mechanisms, and medical device adjustable focus mechanisms. | 02-26-2009 |
20090048612 | MODULAR AND COOPERATIVE MEDICAL DEVICES AND RELATED SYSTEMS AND METHODS - The various embodiments disclosed herein relate to modular medical devices, including various devices with detachable modular components and various devices with pivotally attached modular components. Additional embodiments relate to procedures in which various of the devices are used cooperatively. Certain embodiments of the medical devices are robotic in vivo devices. | 02-19-2009 |
20080233083 | Methods and Compositions for Vaccination of Animals with Prrsv Antigens with Improved Immunogenicity - Pigs challenged with hypoglycosylated variants of Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) major surface protein GP5 exhibited increased production of PRRSV-neutralizing antibodies relative to the levels of neurtalizing antibodies produced by pigs immunized with wild type (wt) or glycosylated GP5. This invention provides for methods of obtaining improved immune responses in pigs to PRRSV, compositions useful for obtaining the improved immune responses as well as isolated polynucleotides that encode hypoglycosylated variants of PRRSV major surface protein GP5. | 09-25-2008 |
20080221591 | METHODS, SYSTEMS, AND DEVICES FOR SURGICAL VISUALIZATION AND DEVICE MANIPULATION - A surgical device includes a console having a visual display and a manipulator arm, a robotic device having a camera and a connection component. The robotic device is configured to be positioned completely within a body cavity. The camera is configured to transmit visual images to the visual display. The connection component operably couples the console and the robotic device. The manipulator arm is positioned relative to the visual display so as to appear to be penetrating the visual display. | 09-11-2008 |
20080201797 | Pearl millet line 53 1 1 with PP3 gene and all derivatives produced by any method - The invention relates to a pearl millet plant, seed, variety, parental line and hybrid. More specifically the invention relates to a pearl millet plant having a mutant allele that increases purple pigmentation in many plant parts. The invention relates to crossing inbreds, varieties, and hybrids containing the purple allele to produce novel types and hybrids of pearl millet and other compatible millet species, both for pigment extraction and ornamental purposes. | 08-21-2008 |