UNIVERSITA DEGLI STUDI DI MILANO Patent applications |
Patent application number | Title | Published |
20150141410 | GPR17 Receptor Modulators - Chemical compounds are provided which act on GPR17 receptors and are useful in the treatment or amelioration of chronic and/or acute neurodegenerative diseases, such as multiple sclerosis, inflammatory diseases, pathologies involving the immune system, cardiovascular diseases, and renal diseases. | 05-21-2015 |
20150119342 | New Homo- and Heterodimeric SMAC Mimetic Compounds as Apoptosis Inducers - The present invention relates to conformationally constrained homo- and heterodimeric mimetics of Smac with function as inhibitors of Inhibitor of Apoptosis Proteins (IAPs), the invention also relates to the use of these compounds in therapy, wherein the induction of apoptotic cell death is beneficial, especially in the treatment of cancer, alone or in combination with other active ingredients. | 04-30-2015 |
20150057159 | METHOD TO IDENTIFY ASYMPTOMATIC HIGH-RISK INDIVIDUALS WITH EARLY STAGE LUNG CANCER BY MEANS OF DETECTING miRNAs IN BIOLOGIC FLUIDS - A diagnostic and/or prognostic model of at least 5 serum miRNAs selected among a group of 34 miRNAs that identifies subjects with early stage lung cancer, namely non-small cell lung carcinomas (NSCLCs), in a population of asymptomatic high-risk individuals, with 80% accuracy. The model could also distinguish between benign and malignant lesions and is sensitive enough to capture the disease onset. In addition, the model could also diagnose or confirm a diagnosis of lung cancer in symptomatic patients, and monitor the lung tumor status after treatment with surgery and/or chemotherapy and/or radiotherapy in a subject with such lung cancer. | 02-26-2015 |
20140162869 | CATALYSTS FREE FROM NOBLE METALS SUITABLE FOR THE ELECTROCHEMICAL REDUCTION OF OXYGEN - The invention concerns new catalysts for the reduction of oxygen suitable for PEM fuel cells, the process for their preparation and their use in other electrolytic processes. | 06-12-2014 |
20130281654 | STAR-AND TREE-SHAPED BRANCHED POLYMERS HAVING FLAME-RETARDANT PROPERTIES - Disclosed are polymers with a complex branched structure (star- or tree-shaped) obtainable by polymerizing a bifunctional type AB monomer and/or type AA+BB monomers in the presence of: a) one or more polyamine and/or a polyacid and/or a polyalcohol and/or more generally a compound (such as POSS) having at least three functional groups such as amino, carboxylic acid or hydroxyl functions; b) one or more phosphorus containing molecules reacting with only one reactive group during the polymerization; c) optionally one or more organic acid and/or an amine and/or an alcohol having one or two functional groups. | 10-24-2013 |
20130064796 | METHODS FOR THE PREVENTION AND CONTROL OF PATHOGENIC INFECTIONS IN BEES AND RELATIVE COMPOSITION - The invention relates to a probiotic mixture for the protection of bees' health, and more specifically for the protection from microbial pathologies, such as those caused by | 03-14-2013 |
20120316212 | AMINO ALCOHOL DERIVATIVES AND THEIR THERAPEUTIC ACTIVITIES - The present invention relates to amino alcohol derivatives of general formula I: | 12-13-2012 |
20120040007 | SERINE PALMITOYLTRANSFERASE INHIBITORS FOR PREVENTING AND DELAYING RETINITIS PIGMENTOSA - The method for preventing and delaying inherited retinal degenerations using serine palmitoyltransferase inhibitors, and compositions which contain them. | 02-16-2012 |
20100267836 | NOVEL MELATONIN LIGANDS HAVING ANTIDEPRESSANT ACTIVITY AS WELL AS SLEEP INDUCING PROPERTIES - Novel melatonin ligands of Formula I: | 10-21-2010 |
20100227336 | METHOD FOR THE MEASURE OF MOLECULAR INTERACTIONS BY MEASUREMENT OF THE LIGHT REFLECTED BY PLANAR SURFACES - Procedure for the quantitative determination of interactions of ligands with receptors adsorbed or immobilized on the surface of a solid material which can be functionalized, transparent and with low refractive index, by direct measure of the reflection of light. | 09-09-2010 |
20100141945 | METHOD OF MEASURING PROPERTIES OF PARTICLES AND CORRESPONDING APPARATUS - A method of measuring properties of particles comprises the steps of generating a beam of radiation (IW); illuminating with the beam (IW) an observation region (MR) which is transited by a particle (B), a portion of the beam (IW) giving rise to radiation (SW) which is scattered by scattering interaction with the particle (B), and another portion (TW) being transmitted substantially undisturbed through the observation region (MR); and detecting, in a detection plane (M), a plurality of radiation intensity values which are determined by the interference between the scattered radiation (SW) and the transmitted radiation (TW). The detection of the radiation intensity values in the detection plane (M) is carried out according to a time sequence of acquisitions corresponding to successive transit positions of the particle through the observation region (MR). On the basis of the time sequence of acquisitions, the trend of a parameter of asymmetry of the distribution of the plurality of radiation intensity values with respect to the optical axis (z), due to the successive transit positions of the particle (B), is determined as a function of time. Depending on the trend of the parameter of asymmetry determined as a function of time, the trends of phase delay and amplitude of the scattered radiation (SW) with respect to the transmitted radiation (TW) are determined as a function of time, and the properties of the particle (B) are determined on the basis of the trends of the phase delay and amplitude of the scattered radiation (SW) as a function of time. | 06-10-2010 |
20090312356 | NICOTINIC AGONISTS SELECTIVE FOR THE ALPHA7 RECEPTOR SUBTYPE, THE PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS THEREFROM - The invention discloses compounds of formula I endowed with agonistic activity at the alpha7 nicotinic acetylcholine receptors (α7 nAChRs), a process for the preparation thereof, pharmaceutical compositions containing the same and the use thereof for the treatment of neurological and psychiatric disorders as well as inflammatory diseases. | 12-17-2009 |
20090078163 | Compression Strength Cement - The present invention relates to the use of raw glycerine as a cement additive in order to improve the compression strength thereof. | 03-26-2009 |
20080269836 | Apparatus for Treating Neurological Disorders by Means of Chronic Adaptive Brain Stimulation as a Function of Local Biopotentials - An apparatus and a related method for the deep brain stimulation have been invented wherein the parameters of the stimulation supplied at the human nervous system level are adjusted and optimized continuously by the analysis of the bioelectric signals coming from the tissue adjacent the stimulation electrode itself, adapting the therapy continuously and in line to the patient's clinical state. The apparatus is constituted at least by an electro-catheter ( | 10-30-2008 |