PRIMERA BIOSYSTEMS, INC.
PRIMERA BIOSYSTEMS, INC. Patent applications | ||
Patent application number | Title | Published |
---|---|---|
20090136951 | QUANTIFICATION OF NUCLEIC ACID MOLECULES USING MULTIPLEX PCR - Described are novel quantification methods and systems that permit, within the context of multiplex PCR, the quantification of all targets within a single reaction tube. The methods employ quantitation algorithms applied to the amplification profiles of internal calibration controls or standards utilizing a plurality of nucleic acid templates that are amplified within the same reaction tube as the nucleic acid target(s) interrogated. | 05-28-2009 |
20090075274 | MULTIPLEXED QUANTITATIVE DETECTION OF PATHOGENS - The invention allows for the quantitative detection of a plurality of pathogens in a single sample. The method includes the amplification of a sample with a plurality of pathogen-specific primer pairs to generate amplicons of distinct sizes from each of the pathogen specific primer pairs. The method further includes the use of a plurality of competitor polynucleotide targets that correspond to each of the pathogen-specific primer pairs. The competitor polynucleotides are added to the reaction mixture at a known concentration to allow for the quantitation of the amount of pathogen in the sample. The method can be used for monitoring pathogen infection in an individual, preferably an immunocompromised individual. | 03-19-2009 |