CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE Patent applications |
Patent application number | Title | Published |
20160123992 | METHODS FOR PREDICTING RHEUMATOID ARTHRITIS TREATMENT RESPONSE - The invention relates to methods and means for predicting rheumatoid arthritis treatment response. | 05-05-2016 |
20160122211 | METHOD AND DEVICE TO REMOVE IONS FROM AN ELECTROLYTIC MEDIA, SUCH AS WATER DESALINATION, USING SUSPENSION OF DIVIDED MATERIALS IN A FLOW CAPACITOR - An object of the present invention is to provide a cheap and efficient method and device to remove ions from an electrolytic media, such as water desalination. | 05-05-2016 |
20160116613 | X-RAY DETECTOR - The invention relates to a matrix device for measuring characteristics of an X-ray beam. The device includes a first set of detection cells of a size different from the cells of at least one second set of detection cells. Each cell corresponds to an ionization chamber including a detection electrode. The detection electrodes of all the cells have the same effective surface for collecting charges. | 04-28-2016 |
20160115199 | Cell Penetrating Peptides for Intracellular Delivery of Molecules - A cell-penetrating peptide characterized in that it comprises an amino acid sequence consisting of XWXRLXXXXXX (SEQ ID No: 5), wherein X in position 1 is beta-A or S; X in positions 3, 9 and 10 are, independently from each other, W or F; X in position 6 is R if X in position 8 is S, and X in position 6 is S if X in position 8 is R; X in position 7 is L or none; X in position 11 is R or none, and wherein X in position 7 is L if X in position 11 is none. | 04-28-2016 |
20160115130 | ALKOXYAMINES FOR THE TREATMENT OF CANCERS - The present invention relates to alkoxyamines of general formula (I), and to compounds of general formula (IIa), (IIb), (IIc), (IId), IIe), (IIf) or (IIg), as such and for the treatment of cancers. | 04-28-2016 |
20160114076 | IMPLANT WITH CONTROLLED POROSITY MADE OF A HYBRID MATERIAL - The disclosure relates to an implant material for filling bone defects, for bone regeneration, and for bone tissue engineering, to an implant comprising this material, to a method for producing such an implant, and to a method for producing a hybrid material. The implant material comprises a hybrid material comprising: a bioactive glass M based on SiO | 04-28-2016 |
20160111709 | METHOD FOR PREPARING AN AMORPHOUS FILM MADE FROM LITHIATED METAL SULFIDE OR OXYSULFIDE - A method of preparing an amorphous film of lithiated metal sulfide or oxysulfide of formula Li | 04-21-2016 |
20160108117 | Anti-CXCL1, CXCL7 and CXCL8 Antibodies and their Applications - The invention provides an isolated antibody or a fragment thereof, which is directed to the human chemokines CXCL1, CXCL7 and CXCL8, said antibody or fragment being capable of binding to the human chemokine CXCL1 with an equilibrium dissociation constant (K | 04-21-2016 |
20160106884 | IMPLANT WITH CONTROLLED POROSITY COMPRISING A MATRIX COVERED BY A BIOACTIVE GLASS OR BY A HYBRID MATERIAL - The disclosure relates to an implant material for filling bone defects, for bone regeneration and for bone tissue engineering, to an implant comprising this material, and to a method for producing such an implant. The implant material comprises: a bioactive glass M based on SiO | 04-21-2016 |
20160089447 | Cell Penetrating Peptides for Intracellular Delivery of Molecules - A cell-penetrating peptide characterized in that it comprises an amino acid sequence X | 03-31-2016 |
20160060296 | Cell Penetrating Peptides for Intracellular Delivery of Molecules - A cell-penetrating peptide characterized in that it comprises an amino acid sequence: X | 03-03-2016 |
20160047750 | DEVICE AND METHOD FOR STIMULATED RAMAN DETECTION - According to one aspect, the invention relates to a device for detecting a resonant non-linear optical signal of Stimulated Raman Scattering (SRS) type induced in a sample. The device comprises electro-optical means for making interact in the sample, at a first modulation frequency, trains of light pulses of angular frequencies ω | 02-18-2016 |
20160046746 | COPOLYMERS CONTAINING VINYLIDENE FLUORIDE AND TRIFLUOROETHYLENE - The subject matter of the invention is a copolymer obtained by free-radical copolymerization of vinylidene fluoride with trifluoroethylene and of at least a third monomer, the third monomer having a molar mass greater than 0 g/mol and corresponding to the formula: in which R | 02-18-2016 |
20160040353 | METHOD FOR DEPOSITING A PHOTOCATALYTIC COATING AND RELATED COATINGS, TEXTILE MATERIALS AND USE IN PHOTOCATALYSIS - A method for depositing a photocatalytic coating on a support, the method having the steps: a) providing an aqueous and/or alcoholic suspension of nanoparticles of a semiconducting material, b) providing a sol in an aqueous and/or alcoholic solution of a hydrolyzed organosilane, c) mixing the suspension and the sol and proceeding with deposition of the obtained mixture on the support to be covered, d) performing a drying operation, e) and optionally producing an illumination of the obtained coating after drying at one wavelength at least causing activation of the semiconducting material, so as to remove at least 3% of the organic groups initially present in the coating and bound to the silicon atoms through a Si—C bond; as well as coatings with photocatalytic properties, materials, notably textiles, covered with such a coating and the use of such coatings and materials for photocatalysis. | 02-11-2016 |
20160040299 | METHOD FOR PREPARING A CARBIDE CERAMICS MULTILAYER COATING ON, AND OPTIONALLY IN, A PART MADE OF A CARBON-CONTAINING MATERIAL USING A REACTIVE MELT INFILTRATION RMI TECHNIQUE - A method preparing a metals carbides multilayer coating on at least one surface of a first carbon layer of a substrate, or under the surface inside the first carbon layer, by a reactive melt infiltration technique, includes: a) putting the surface into contact with a solid metal disilicide MSi | 02-11-2016 |
20160040187 | RECOMBINANT MEASLES VIRUSES EXPRESSING EPITOPES OF ANTIGENS OF RNA VIRUSES - USE FOR THE PREPARATION OF VACCINE COMPOSITIONS - The invention relates to a recombinant measles virus expressing a heterologous amino acid sequence derived from an antigen of a determined RNA virus, said recombinant measles virus being capable of eliciting a humoral and/or cellular immune response against measles virus or against said RNA virus or against both measles virus and against said RNA virus. It also relates to the use of said recombinant measles virus for the preparation of immunogenic composition. | 02-11-2016 |
20160040028 | NOVEL AMPHIPHILIC POLYMERS AND USE THEREOF IN THE TREATMENT OF SURFACES MADE OF HYDROPHOBIC MATERIALS - A straight, branched or cross-linked polymer, including, per 100 mol %: a) a mole fraction from 75% to 99.95% of monomer units from an N,N-dialkyl acrylamide; b) a mole fraction from 0.05% to 1% of monomer units from a monomer of formula (I): CH2=C(Ri)-C(=0)-0-[(CH2-CH(R2)-0]n-R3 (I); c) optionally a mole fraction higher than 0% to 24% either of monomer units from a monomer including a free strong acid function, partially or totally salified, or of monomer units from a monomer of formula (II): CH2=C(R4)-C(=0)-Y-(CH2)m-N(R5)(R6) (II); d) optionally a mole fraction higher than 0% to 1% of a diethylene or polyethylene cross-linking monomer. Also, a method for treating a surface made of a hydrophobic material, using the polymer, and an aqueous, hydro-organic or organic solution including the polymer for modifying interactions between the species contained the solution and the hydrophobic surface. | 02-11-2016 |
20160035581 | MICROELECTRONIC METHOD FOR ETCHING A LAYER - A microelectronic method for etching a layer to be etched, including: modifying the layer to be etched from a surface of the layer to be etched and over a depth corresponding to at least a portion of thickness of the layer to be etched to form a film, with the modifying including implanting light ions into the layer to be etched; and removing the film includes a selective etching of the film relative to at least one layer underlying the film. | 02-04-2016 |
20160033174 | ABSORBENT MATERIAL AND SOLAR PANEL USING SUCH A MATERIAL - The invention concerns a multilayer material comprising at least:
| 02-04-2016 |
20160028205 | Fiber-Optic Laser Oscillator - The invention relates to a laser oscillator comprising an amplifying optical fibre (MA) inserted in a resonant cavity so as to act as an active medium, and pumping means (DL, CP) causing a population inversion in said amplifying optical fibre, characterized in that said amplifying optical fibre comprises at least two cores (C1, C2) optically coupled to each other in a common cladding (G), and in that the shapes, sizes, refractive indices and the relative arrangement of said cores are chosen so that super-modes are supported, at least one (SMI) of which super-modes has, in an emission spectral band of said laser oscillator, a normal chromatic dispersion. | 01-28-2016 |
20160018416 | NEW DUAL BIOMARKER OF NEURODEGENERATION AND OF NEUROREGENERATION - A new dual biomarker of neurodegeneration and of neuroregeneration | 01-21-2016 |
20160006039 | BIOCOMPATIBLE ELECTROCHEMICAL SUPERCAPACITOR - A supercapacitor to be submerged in a medium containing a biological material and an oxidant, wherein the anode comprises a first enzyme that can catalyse the oxidation of the biological material and the cathode comprises a second enzyme that can catalyse the reduction of the oxidant, and wherein each of the anode and cathode electrodes consists of a solid agglomerate of a conductive material mixed with the first or the second enzyme, said agglomerate having a specific surface that is larger than or equal to 20 m | 01-07-2016 |
20160002368 | METHOD FOR PREPARING A HYDROGEL MATRIX BY PHOTOPOLYMERIZATION - The invention relates to a method for preparing a hydrogel type matrix comprising at least two contiguous zones with distinct stiffnesses, comprising a step to photopolymerize a solution comprising one or several polymerizable compounds and a photopolymerization initiator, by application of light onto the entire solution and at a different intensity in at least two zones of the solution, as a result of which a hydrogel matrix is obtained comprising at least two contiguous zones with distinct stiffnesses, characterized in that the photopolymerization step is done in the presence of a polymerization catalyst. | 01-07-2016 |
20150380771 | METHOD FOR SYNTHESIZING IONIC LIQUIDS HAVING A CARBONATE FUNCTIONAL GROUP AND IONIC LIQUIDS THUS OBTAINED - The present invention relates to a method for synthesizing ionic liquids comprising a carbonate functional group characterized in that it comprises a step of reaction A without addition of lithium between a first reactant selected among an imidazolium, a pyrrolidinium or an ammonium and a second reactant being a methyl formate imidazolium. The first reactant is an imidazolium alcohol, a pyrrolidinium alcohol or an ammonium alcohol salt, the anion of which is NTf2. The second reactant is a chloromethyl formate imidazolium. | 12-31-2015 |
20150376757 | METHOD FOR DEPOSITING A CORROSION-PROTECTION COATING FROM A SUSPENSION - Process for depositing a coating on a substrate having at least one cavity, comprising a step of mixing ground powders of an activating agent and a powder of the metal or of the alloy to be deposited on the substrate that were ground in step a) and a liquid so as to form a suspension, and a step of applying the suspension to the portion of the substrate to be coated. | 12-31-2015 |
20150374610 | TOPICAL PROTECTIVE POLYMERIZED NANOPARTICLES IN AN ACTIVE OR BIOACTIVE ARRAY, METHODS FOR PREPARING SAME AND USES THEREOF - The invention concerns a compound formed by functionalised micro- or nanoparticles covalently associated with rheology-modifying polymers. The invention is characterised in that the functionalised micro- or nanoparticles are functionalised inorganic or metal oxide micro- or nanoparticles, in particular aluminium oxide (Al | 12-31-2015 |
20150368782 | METHOD FOR DEPOSITING A CORROSION-PROTECTION COATING - The use of a cement in a process for pack cementation deposition on a substrate having cavities of minimum equivalent diameter e | 12-24-2015 |
20150362571 | METHOD FOR ANALYSIS BY NUCLEAR MAGNETIC RESONANCE OF A SAMPLE INCLUDING A SPECIES TO BE CHARACTERIZED AND A REFERENCE SPECIES - Method for analyzing, using nuclear magnetic resonance, at least one sample including at least one species to be characterized and a reference species having a content, in the sample, that is more than twice greater than the content of the species to be characterized, the method includes:
| 12-17-2015 |
20150353675 | CATALYTIC SYSTEMS FOR THERMOSETTING RESINS WHICH ARE DEFORMABLE IN THE THERMOSET STATE - The invention relates to a composition containing at least one catalyst (C1) containing at least one atom of an element (M1) chosen from: Al, Sc, Ti, Mg, Mn, Fe, Co, Ni, Cu, Zn, Zr, Sn, Hf, Pb, Si, Sb and In; a catalyst (C2) comprising at least one atom of an element (M2) chosen from alkali metals and alkaline-earth metals; a thermosetting resin and/or a hardener for a thermosetting resin. The invention also relates to the use of this composition for rendering a resin which is in the thermoset state hot-deformable and nevertheless free of any residual stress after the deformation thereof; such a resin will advantageously retain its shape even if it is subsequently subjected to high temperatures. The invention relates, moreover, to kits for preparing the composition, to a thermoset-resin-based object obtained from a composition of the invention, to a process for manufacturing objects, to a process for hot-deformation of objects and to various possible uses of the compositions and objects of the invention. | 12-10-2015 |
20150344853 | CONSTRUCTION OF NEW VARIANTS OF DEXTRANSUCRASE DSR-S BY GENETIC ENGINEERING - The present invention relates to a recombinant process for the production of truncated or mutated dextransucrases while conserving the enzymatic activity or their specificity in the synthesis of the α-1,6 bonds. The present invention relates to nucleic acid sequences of truncated or mutated dextransucrases, vectors containing the nucleic acid sequences and host cells transformed by sequences encoding truncated or mutated dextransucrases. In another aspect, the invention concerns a method for producing, in a recombinant manner, truncated or mutated dextransucrases which conserve their enzymatic activity or which conserve their specificity in the synthesis of α-1,6 bonds and can produce, from saccharose, dextrans with high molar mass and modified rheological properties compared with the properties of dextran obtained with the native enzyme and isomalto-oligosaccharides with a controlled molar mass and dextrans. The dextrans and isomalto-oligosaccharides of the invention can be used namely as texturing agents or as prebiotics. | 12-03-2015 |
20150344773 | Hybrid Polymer with High Cluster Content - This deals with a luminescent salt comprising a metal cluster anion and an organic cation, wherein the metal cluster anion comprises a metal cluster with at least two metal atoms, and ligands, the metal atoms being chosen from the group consisting of molybdenum, rhenium, tungsten, thallium, niobium, and mixtures thereof, wherein the organic cation comprises a cationic head substituted by at least one substituent including a polymerisable functional group. It also deals with a polymeric material comprising a polymer matrix which has polymerised with this luminescent salt. | 12-03-2015 |
20150344552 | ANTIBODY AGAINST THE PROTEIN TRIO AND ITS METHOD OF PRODUCTION - Disclosed are specific antibodies against the protein Trio, their method of production, and their use in in vitro cancer prognostic method. Also described are the antigens enabling production of the antibodies. | 12-03-2015 |
20150342517 | METHOD AND APPARATUS FOR ASSESSING PROPRIOCEPTIVE STATUS FOR AT LEAST ONE JOINT OF A PERSON - The present invention relates to a method of assessing proprioceptive status by calculating a proprioceptive score Sp from absolute and variable errors between target angles and angles estimated and joint motion detection by the person tested, and/or between measured time of perceived movement of the joint of the tested person these proprioceptive scores of a person being associated with an assessment date and then stored with a date so as to serve as a reference when said person is monitored or when there is a comparison of said person with at least another person. The present invention also concerns an apparatus for the proprioceptive assessment of at least one joint, this apparatus having two movable parts ( | 12-03-2015 |
20150338391 | IN VITRO DIAGNOSTIC METHOD FOR AN INVASIVE FUNGAL INFECTION USING MALDI-TOFF MASS SPECTROMETRY - A method for the in vitro diagnosis of an invasive fungal infection by MALDI-TOF mass spectrometry. The method involves, providing a liquid biological sample from a mammal, said biological sample containing, in particular, proteins and/or lipids and/or salts and/or polysaccharides and/or oligosaccharides and/or monosaccharides capable of forming complexes with said proteins and/or lipids and/or salts; treating said sample with biological liquid so as to extract said polysaccharides and/or oligosaccharides and/or monosaccharides; determining, by MALDI-TOF mass spectrometry, whether or not there is present among said extracted polysaccharides, oligosaccharides and/or monosaccharides, at least one given compound of interest coming from said fungal microorganism and chosen from polysaccharides, oligosaccharides and monosaccharides; and deducing, if said given compound of interest is present in said sample, that said mammal is suffering from an invasive fungal infection. | 11-26-2015 |
20150329428 | PROCESS FOR PREPARING CERAMICS, CERAMICS THUS OBTAINED AND USES THEREOF, ESPECIALLY AS A SPUTTERING TARGET - A method for preparing a ceramic from an inorganic base material in the form of a powder with a high boiling point, including a step in which the powder of the inorganic base material is mixed with a second inorganic component which is also in powder form and which serves as a dopant for the inorganic base material. The dopant comprises a single inorganic material or a mixture of at least two inorganic materials that have a dopant effect on the inorganic base material. The method also includes a sintering step performed at a high temperature. Owing to the high density thereof, the resulting ceramics are suitable for use as a target element. The films and electrodes obtained from said ceramics have particularly beneficial properties. | 11-19-2015 |
20150328625 | MODIFIED Y-TYPE ZEOLITES HAVING A TRIMODAL INTRACRYSTALLINE STRUCTURE, METHOD FOR MAKING SAME, AND USE THEREOF - The invention relates to a Y-type zeolite having a modified faujasite structure, the intracrystalline structure of which includes at least one network of micropores, at least one network of small mesopores having an average diameter ranging from 2 to 5 nm, and at least one network of large mesopores having an average diameter range from 10 to 50 nm. The invention also relates to particles including such zeolites and to the use thereof in a method for processing crude oil, particularly as a hydrocracking catalyst. | 11-19-2015 |
20150318073 | TALC COMPOSITION - An electrically conducting talc composition may include synthetic talc particulate coated with an electrically conducting coating agent, wherein the coating agent may include carbon nanotubes or an electrically conductive polymeric material, such as a nanocarbon material, such as, for example, carbon nanotubes. A method of making an electrically conducting talc composition may include forming electrically conducting coating agent on or about particles of the talc particle. | 11-05-2015 |
20150311796 | DC-DC HIGH VOLTAGE CONVERTER - A DC-DC voltage converter including a main switch formed by a normally ON switch element connected in series with a normally OFF switch element including a control circuit, a load in series with the main switch, the main switch and the load being configured to be connected to terminals of a DC voltage source. A voltage source, that can be used for controlling is obtained by connecting a main peak detector circuit to the mid-point of the main switch. The control circuit of the normally OFF switch element can be supplied with the DC voltage that makes the entire device self-supplied. Such a converter can, for example, find application in aeronautics. | 10-29-2015 |
20150308717 | Improved Element for Processing Solar Radiation, and a Sun Tracker and a Solar Farm Equipped with Such an Element - An element for processing solar radiation includes means for processing solar radiation forming a layer of the solar radiation processing element and includes a layer of radiation-emitting material, especially infrared radiation, covering the layer of the processing means. A sun tracker includes at least one processing element and a solar farm includes a series of sun trackers, each comprising a processing element. | 10-29-2015 |
20150307450 | NEW DERIVATIVES OF INDOLE FOR THE TREATMENT OF CANCER, VIRAL INFECTIONS AND LUNG DISEASES - The present invention relates to a new class of indole derivatives, having a particular MKlp2 inhibition profile and useful as a therapeutic agent, in particular for the treatment of cancer, viral infections and lung diseases. | 10-29-2015 |
20150302841 | HAPTIC CONTROLLER SUITABLE FOR CONTROLLING A SOUND CHARACTERISTIC - The invention relates to a haptic controller comprising a base ( | 10-22-2015 |
20150297025 | Cooking Device Comprising a Cooking Surface That is Easy to Clean and Resistant to Scratching - The present invention relates to a cooking device including a metal holder supporting a ceramic cooking surface, the holder having a hardness no lower than 150 HV. The holder forms a substrate supporting a surface layer made of a transition metal boride or boronitride forming the cooking surface. The present invention further relates to a culinary article including a cooking device of the type above-mentioned, a household cooking appliance including a cooking device of the type above-mentioned, as well as a method for producing a cooking device of the type above-mentioned. | 10-22-2015 |
20150293787 | Method For Scheduling With Deadline Constraints, In Particular In Linux, Carried Out In User Space - A method for scheduling tasks with deadline constraints, based on a model of independent periodic tasks and carried out in the user space by means of API POSIX is provided. | 10-15-2015 |
20150291568 | NEW COMPOUNDS HAVING A PROTECTIVE ACTIVITY AGAINST TOXINS WITH INTRACELLULAR ACTIVITY - The present invention concerns a new family of 2,3-dihydroquinazolin-4(1H)-one compounds of general formula (I), and the use thereof as inhibitors of the toxic effects of toxins with intracellular activity, such as ricin or Shiga toxin, for example, using retrograde transport to intoxicate cells. | 10-15-2015 |
20150289410 | ELECTRONIC DEVICE WITH COOLING BY A LIQUID METAL SPREADER - An electronic device with cooling of a heat dissipation source, by a liquid metals spreader, the device including at least one heat dissipation source, at least one spreader through which at least one liquid metal circulation channel passes forming a loop routed below a heat dissipation source, at least one heat sink, and at least one electromagnetic pump moving the liquid metal in the at least one channel such that the liquid metal absorbs heat dissipated by a heat dissipation source and transports the absorbed heat to be evacuated by the heat sink. Each spreader includes at least two plates made of an electrical insulating material located on each side of at least one bar made of deformable material. | 10-08-2015 |
20150285811 | MULTIFUNCTIONAL COUPLING REAGENTS HAVING AN AZLACTONE FUNCTION - Novel compounds, having an azlactone function, of formula (I), to be used as multifunctional coupling agents, and a method for coupling a biomolecule and a target molecule using such a compound are described. A diagnosis reagent, a kit for implementing the coupling method, a method for separating, detecting and/or characterizing at least one molecule of interest, and a composition including a novel compound are also described. | 10-08-2015 |
20150285719 | METHOD OF FORMING AN AGGREGATE OF OBJECTS - A method of forming an aggregate of objects in a channel including a liquid, said method including: a) providing objects in at least a region of the channel, and b) forming an aggregate of said objects by submitting them to a modulated pulsed acoustic field, wherein the modulated pulsed acoustic field applied at step b) is modulated in amplitude. | 10-08-2015 |
20150283228 | Recombinant Feline Leukemia Virus Vaccine Containing Optimized Feline Leukemia Virus Envelope Gene - The present invention provides vectors that contain and express in vivo or in vitro FeLV antigens that elicit an immune response in animal or human against FeLV, compositions comprising said vectors and/or FeLV polypeptides, methods of vaccination against FeLV, and kits for use with such methods and compositions. | 10-08-2015 |
20150280733 | SIGMA DELTA RF MODULATOR HAVING CAPACITIVE COUPLING, ANALOG/DIGITAL CONVERTER AND APPARATUS INCLUDING SUCH A MODULATOR - A continuous-time sigma delta radio frequency modulator is provided, including at least two LC resonators coupled in parallel by a coupling capacitive element, producing an at least 4 | 10-01-2015 |
20150275184 | INFECTIOUS CDNA OF AN APPROVED VACCINE STRAIN OF MEASLES VIRUS, USE FOR IMMUNOGENIC COMPOSITIONS - The invention relates to a cDNA molecule which encodes the nucleotide sequence of the full length antigenomic (+)RNA strand of a measles virus (MV) originating from an approved vaccine strain. It also concerns the preparation of immunogenic compositions using said cDNA. | 10-01-2015 |
20150244727 | METHOD FOR AUTHENTICATING A SECURITY ELEMENT BY SUPERIMPOSING N SHARED COLOUR IMAGES, AND SECURITY ELEMENT IMPLEMENTING SAID METHOD - A method for authenticating a security element by superimposing N shared colour images in order to obtain at least one target colour may include a phase of constructing an authenticator system that includes a step of selecting a target colour; a step of selecting a series of N decomposition colours which, by means of superimposition, together enable the target colour to be obtained; and a step of recording the N shared images each with a decomposition colour from the series. A security element comprising at least one shared image may be obtained according to the method. | 08-27-2015 |
20150241357 | METHOD AND SYSTEM FOR ANALYSING PARTICLES IN COLD PLASMA - The invention relates to a method of analyzing particles, in particular particles of diameter less than 1 μm, the method comprising the following steps:
| 08-27-2015 |
20150233933 | EZRIN ASSAY METHOD FOR THE IN VITRO DIAGNOSIS OF COLORECTAL CANCER - A method for the in vitro diagnosis of colorectal cancer by determining the presence of the Ezrin tumor marker in a biological sample taken from a patient suspected of having colorectal cancer using at least one anti-Ezrin monoclonal antibody directed against an Ezrin epitope chosen from the epitopes of sequence SEQ ID No.1, SEQ ID No.2, SEQ ID No.3, SEQ ID No.4+SEQ ID No.5, SEQ ID No.6+SEQ ID No.7 and SEQ ID No.8. Said method can be used for early diagnosis, screening, therapeutic follow-up and prognosis, and also for relapse diagnosis in relation to colorectal cancer. | 08-20-2015 |
20150232876 | Use of a Receptor Kinase Having LysM Motifs in Order to Improve the Response of Plants to Lipochitooligosaccharides - The invention relates to improving the response of a plant to lipochitooligosaccharidic Nod and Myc-LCO factors, by means of the expression, in the plant, of a polypeptide which has a sequence homology with the extracellular domain of the LysM-motif-containing receptor kinase LYR3 in | 08-20-2015 |
20150229031 | Electromagnetic Absorber - The invention concerns an electromagnetic absorbent comprising: a metal earth plane, an insulating dielectric substrate, disposed on said metal earth plane, a set of metal resonant elements disposed on said insulating dielectric substrate, the electromagnetic resonant frequency of a resonant element being adjusted by adapting the dimensions of the resonant element, the set of resonant elements comprising resonant elements with different dimensions so as to enable the production, by juxtaposition of different electromagnetic resonant frequencies, of a predetermined electromagnetic absorption band. An elementary pattern formed by a plurality of metal resonant elements can be replaced periodically. | 08-13-2015 |
20150219539 | METHOD OF DETERMINING THE NON-PROPAGATION THRESHOLD OF FATIGUE CRACKS AT HIGH FREQUENCY - A method of determining the non-propagation threshold of fatigue cracks at high frequency, wherein cyclic loading is exerted on at least one testpiece having an elliptical hole in a testpiece zone, the elliptical hole having a notch at one end and the testpiece being held between two rigid masses with two rigid pre-stress plates being arranged on either side of the at least one testpiece and each fastened at its two ends to the two rigid masses, which cyclic loading is at a frequency that is selected as being equal to the resonant frequency of the assembly including the testpiece, the masses, and the stress plates, so as to generate a fatigue crack from the notch, and then once it has been observed that the crack has stopped propagating, the final length of the crack is measured and a chart is used to determine the non-propagation threshold. | 08-06-2015 |
20150218306 | METHOD FOR PREPARING A POLYMER FROM AT LEAST ONE CYCLIC MONOMER - The present invention relates to a method for preparing a copolymer from at least one cyclic monomer selected from: a lactone, a lactam, a carbonate, a lactide and a glycolide, an oxazoline, an epoxide, a cyclosiloxane, comprising the step consisting of reacting said cyclic monomer in the presence of a substituted phosphorus-containing compound. | 08-06-2015 |
20150216962 | REVERSE GENETICS OF NEGATIVE-STRAND RNA VIRUSES IN YEAST - The present invention relates to a methodology for the generation of infectious ribonucleoparticles (RNPs) of negative-strand RNA viruses, and in particular of non-segmented negative-strand RNA viruses in yeast, especially in budding yeast. Accordingly, the patent application relates to a recombinant yeast strain suitable for the rescue of infectious non-segmented negative-strand RNA virus particles or infectious virus-like particles. The invention also relates to the use of the recombinant yeast to prepare vaccine seed and to the use of the produced RNPs or RNPs-like to prepare vaccine formulations. It also concerns the use of the recombinant yeast for the screening of libraries of DNA. | 08-06-2015 |
20150204816 | METHOD FOR SEPARATING BIOLOGICAL MOLECULES AND CELLS IN SOLUTION - A method for separating a plurality of deformable objects, such as biological cells or biological supramolecules such as DNA, in a liquid medium by use of an electrophoretic technique combined with hydrodynamic forces. The deformable objects are introduced into a channel, having a flow axis and a cross section at right angles to the flow axis, with the minimum size of the cross section being less than or equal to 50 pm; A hydrodynamic flow is defined a in the channel together with the application of an electric field in the channel, making it possible to move the deformable objects in the channel according to the flow axis and to separate them along the flow axis. A device suitable for implementing this method. The electrolyte used for the electrophoretic separation may be a non-Newtonian fluid with viscoelastic properties. | 07-23-2015 |
20150203809 | CELL CULTURE - The disclosure relates to the fabrication of a three dimensional [3-D] cell culture membrane comprising one or more functionalized surfaces adapted to provide cell culture conditions suitable for the analysis of proliferation, differentiation or function of cells, typically eukaryotic or prokaryotic cells. | 07-23-2015 |
20150203366 | REVERSIBLE TRAPPING ON ACTIVATED CARBON - A cyclic process is provided for reversible adsorption of emerging pollutants or micropollutants for depolluting a contaminated aqueous medium. The process is carried out without oxygen-containing gas, and without the provision of radical initiators, and includes a plurality of cycles, each cycle having the following steps: a. the adsorption of the emerging pollutants and micropollutants contained in the aqueous medium onto an activated carbon felt electrode by bringing the contaminated aqueous medium into contact with the activated carbon felt electrode making it possible to adsorb the emerging pollutants and micropollutants contained in the aqueous medium onto the activated carbon felt electrode; and b. the in situ regeneration of the activated carbon felt electrode by negative polarization allowing the electrochemical desorption of the emerging pollutants and micropollutants adsorbed in step a) and the re-use of the activated carbon felt electrode in the next cycle, and use thereof for depolluting aqueous media. | 07-23-2015 |
20150191745 | LENTIVIRAL TRIPLEX DNA, AND VECTORS AND RECOMBINANT CELLS CONTAINING LENTIVIRAL TRIPLEX DNA - The present invention provides nucleic acid, vectors, viruses, and recombinant cells comprising triple-stranded structures, such as those resulting from central initiation and termination of HIV-1 reverse transcription at the center of HIV-1 linear DNA genomes. These triplex structures can act as a cis-determinant of HIV-1 DNA nuclear import, allowing infection of non-dividing target cells. In one aspect, the presence of the DNA triplex sequence in an HIV vector strongly stimulates gene transfer in hematopoietic stem cells. The invention also provides methods of using these triplex structures for making recombinant cells, as well as methods of using the recombinant cells to express proteins of interest both in vitro and in vivo. | 07-09-2015 |
20150174222 | MODIFICATION OF THE IMMUNOMODULATORY EFFECTS OF CELLS - The present invention relates to an isolated cell having immunomodulatory potential, in which the expression and/or activity of periostin is modulated, or to the culture supernatant of said cell, for the use thereof as an immunosuppressive or immunostimulatory drug. The present invention also relates to periostin for the use thereof as an immunostimulatory drug or to a periostin inhibitor for the use thereof as an immunosuppressive drug. | 06-25-2015 |
20150158989 | METHOD FOR CHEMICAL FOAMING IN THE PRESENCE OF REINFORCING FILLERS - The present invention relates to a method for preparing a foamed item, including the following steps: a) heating a composition including, or consisting of, at least one polyamide PA, at least one compound U including at least one urethane function, particularly a polyurethane PU, at least one reinforcing filler, the content of which is no lower than 10 wt % of the total weight of the composition, and temperature T such that: the compound U directly or indirectly generates CO | 06-11-2015 |
20150153162 | METHOD OF THREE-DIMENSIONAL MEASUREMENTS BY STEREO-CORRELATION USING A PARAMETRIC REPRESENTATION OF THE MEASURED OBJECT - In the field of methods of three-dimensional measurement of an object by stereo-correlation, methods require at least two cameras connected to image processing means. These methods include at least a first step of calibration of the two image planes and a second step of spatial matching between these two image planes. These two steps can be followed by a third step of temporal matching. The method provided requires objects, the surface of which has a parametric representation, i.e. a mathematical representation of the object surface having the form of a decomposition over a scalar function basis. The parametric representation is implemented during the first calibration step and/or during the second and third steps of spatial or temporal matching. | 06-04-2015 |
20150151005 | MICROPARTICLES AND NANOPARTICLES MADE UP OF HYDROPHOBIZED POLYSACCHARIDES AND AN ALPHA-CYCLODEXTRINE - Microparticles and nanoparticles of hydrophobized polysaccharide and an alpha-cyclodextrin, obtained by self-association in an aqueous medium, the hydrophobized polysaccharide being obtained by grafting of alkyl chains derived from fatty acids, by an acylation reaction. These microparticles and nanoparticles constitute systems used for encapsulating substances of interest, in particular in the pharmaceutical field, and vectorization thereof for therapeutic purposes. | 06-04-2015 |
20150139595 | DEVICE FOR CONVERTING THE TRANSVERSE SPATIAL PROFILE OF INTENSITY OF A LIGHT BEAM, PREFERABLY USING A MICROSTRUCTURED OPTICAL FIBRE - A device for converting transverse spatial profile of intensity of a light beam, using a microstructured optical fiber. Transverse dimensions of the fiber vary longitudinally and both its ends have opto-geometrical parameters such that at the wavelength of the beam the fiber has a fundamental mode having two different profile shapes at its two ends. Thus by introducing the beam with one of the profiles through one of the two ends, the beam emerges through the other end with the other profile, whose shape is different from that of the profile of the introduced beam. | 05-21-2015 |
20150121569 | MICROPEPTIDES AND USE THEREOF FOR MODULATING GENE EXPRESSION - Process for detecting and identifying micropeptides (miPEPs) encoded by a nucleotide sequence contained in the sequence of the primary transcript of a microRNA and use thereof for modulating gene expression. | 04-30-2015 |
20150119745 | METHOD FOR CHARACTERISING THE PHYSIOLOGICAL STATE OF A PATIENT FROM THE ANALYSIS OF THE CEREBRAL ELECTRICAL ACTIVITY OF SAID PATIENT, AND MONITORING DEVICE APPLYING SAID METHOD - The invention relates to a method for detecting a physiological state of a patient deviating from a reference physiological state, in which, after having determined, in each of Q frequency bands, R reference matrices PR | 04-30-2015 |
20150118259 | 28 KDA GST PROTEINS FROM SCHISTOSOMA FOR THE USE THEREOF IN THE TREATMENT OF INFLAMMATORY AUTOIMMUNE DISEASES GENERATING A TH1 AND/OR TH17 RESPONSE - The present invention relates to a product selected from a protein, a fragment of the protein, a derived sequence and a homologous sequence of the protein, the protein including or being constituted by the 28 kDa glutathione S-transferase protein from a schistosome selected from | 04-30-2015 |
20150111729 | EXHAUST GAS TREATMENT CATALYST - Catalyst system suitable especially for the removal of CO compounds, comprising or consisting of an oxide, preferably of fluorite crystalline structure, conforming to the following molar formulation: | 04-23-2015 |
20150111718 | PRODUCT MADE OF DENSE SILICON CARBIDE - Sintered product exhibiting a relative density of greater than 97% and composed of:
| 04-23-2015 |
20150105281 | Method for the Selection of Serum Biomarkers of Epigenetic Alterations, Particularly of Global Hypomethylation and Their Uses - The present invention provides a novel method for the selection of serum biomarkers of epigenetic alterations, particularly of global hypomethylation, and the use of said biomarkers in a method for screening, diagnosing and following a pathology associated to epigenetic alterations of cell in an individual, such as placental-related pathology or cancer. The present invention also relates to a method of detecting a predisposition to placental-related pathology or cancer based on the presence or the level of said biomarker in a serum or plasma sample of said patient. The present invention also relates to a method for predicting and following the effect of drugs targeting epigenetic modifications and in particular the effect of demethylating agents. The present invention is directed to a kit comprising such serum biomarkers of epigenetic alterations, particularly of global hypomethylation. | 04-16-2015 |
20150079297 | METHOD OF COATING A FIBER WITH PRE-COATING - A method of depositing a coating of a first metal alloy on a fiber extending in a main direction, including: a) heating a first mass of a first metal alloy above its melting temperature; and b) moving the fiber through the liquid first mass to be covered by a coating of a non-zero thickness over the entire periphery of the fiber; and prior to a): i) providing a second mass of a second metal alloy having a higher melting temperature than the first alloy; j) heating the second mass to above its melting temperature to be in its liquid state and then moving the fiber through the second alloy such that the second alloy is taken up under visco-capillary conditions and the fiber becomes covered over a portion by a coating of the second alloy of non-zero thickness; and k) cooling the second coating until it becomes solid. | 03-19-2015 |
20150072442 | SPIN INJECTOR DEVICE COMPRISING A PROTECTION LAYER AT THE CENTRE THEREOF - A method for manufacturing a spin injector device, comprising the following steps of:
| 03-12-2015 |
20150057231 | Use of Engrailed Proteins for Increasing Dopamine Synthesis by Dopaminergic Neurons - The invention relates to the use of an Engrailed protein as a medicament for increasing dopamine synthesis by dopaminergic neurons, in particular in the management of conditions associated with a decrease of dopamine levels without loss of dopaminergic neurons | 02-26-2015 |
20150056126 | PROCESS FOR PREPARING A CARBON FOAM AND USE OF THE MATERIAL OBTAINED - The present invention relates to a process for preparing a carbon foam, from selected oxocarbons or pseudo-oxocarbons, at low temperatures and to the use of the material obtained via the implementation of this process for the manufacture of a system for detecting light waves. | 02-26-2015 |
20150050282 | GLYCOCONJUGATES AND USE THEREOF AS VACCINE AGAINST SHIGELLA FLEXNERI SEROTYPE 3a AND X - The present invention relates to compounds derived from sugars which reproduce the epitopes of | 02-19-2015 |
20150044717 | DEVICES AND METHODS FOR OBSERVING EUKARYOTIC CELLS WITHOUT CELL WALL - The present invention relates to methods and devices for observing eukaryotic cells devoid of cell wall, in particular for observing the cytokinetic ring, the device comprising a plurality of wells suitable for containing only one single eukaryotic cell and characterized in that the dimensions of the wells constrain the cells into an oblong shape with a long axis parallel to the depth of the wells. | 02-12-2015 |
20150044237 | CHIMERIC MOLECULE INVOLVING OLIGOMERIZED FASL EXTRACELLULAR DOMAIN - New chimeric molecules involving in their structure, a combination of the extracellular domain (EC) of the FasL protein and a domain enabling oligomerisation of this Fas Ligand (FasL) EC domain, such as the Ig-like (so-called Ig in the following pages) domain of the gp190 receptor for the Leukemia Inhibitory Factor (LIF), or involving in their structure variants of the domains. Also, compositions including the chimeric molecule defined herein and the use of these chimeric molecules especially to trigger cytotoxic activity toward cells sensitive to FasL. | 02-12-2015 |
20150038647 | TELECHELIC POLYOLEFIN AND PREPARATION THEREOF - Telechelic polyolefin of formula(I) and its derivatives: | 02-05-2015 |
20150037909 | Electronic Nose or Tongue Sensors - The present invention relates to a sensor for an electronic tongue or nose for analysing a sample or detecting a target. The sensor comprises a support, on one surface of which a plurality of sensitive areas are located, each sensitive area comprising at least one receptor and being capable of transmitting a measurable signal generated by the interaction of at least one constituent of the sample or one target with at least one receptor. The sensor is characterised in that it comprises at least three sensitive areas that differ from one another in terms of their respective receptor compositions, at least one of the sensitive areas comprising a mixture of at least two different receptors, while the two other sensitive areas each comprise at least one of the two receptors. | 02-05-2015 |
20150037837 | Cytological Method Using the Auto Fluorescence of White Corpuscles for the Early Diagnosis and the Monitoring of Infections - The present invention relates to an in vitro method for diagnosing the infectious state of an individual on the basis of a sample of white corpuscles arising from a biological specimen taken from an organ potentially infected by a pathogenic micro-organism of said individual, comprising at least the following two steps: i) measuring the mean cellular intensity of the autofluorescence of said sample, and ii) comparing the intensity measured in step i) with a control value, so as to determine the infectious state of said individual. The diagnostic method of the invention uses a routine optical material making it possible to work in wavelength regions which are compatible with the cellular autofluorescence, and thus constitutes a rapid, reliable and inexpensive aid for the diagnosis or monitoring of an infection in an individual. | 02-05-2015 |
20150030623 | Recombinant Feline Leukemia Virus Vaccine Containing Optimized Feline Leukemia Virus Envelope Gene - The present invention provides vectors that contain and express in vivo or in vitro FeLV antigens that elicit an immune response in animal or human against FeLV, compositions comprising said vectors and/or FeLV polypeptides, methods of vaccination against FeLV, and kits for use with such methods and compositions. | 01-29-2015 |
20150017322 | SULPHATES OF USE AS ELECTRODE MATERIALS - The invention relates to an electrode material. | 01-15-2015 |
20150011749 | USE OF CERTAIN METAL-ACCUMULATING PLANTS FOR THE PERFORMANCE OF ORGANIC CHEMISTRY REACTIONS - Metal-accumulating plants for preparing compositions including a metal catalyst derived from the plants. The composition is substantially devoid of organic matter. Also, carrying out chemical reactions with the compositions prepared from metal-accumulating plants. | 01-08-2015 |
20150011006 | LENTIVIRAL TRIPLEX DNA, AND VECTORS AND RECOMBINANT CELLS CONTAINING LENTIVIRAL TRIPLEX DNA - The present invention provides nucleic acid, vectors, viruses, and recombinant cells comprising triple-stranded structures, such as those resulting from central initiation and termination of HIV-1 reverse transcription at the center of HIV-1 linear DNA genomes. These triplex structures can act as a cis-determinant of HIV-1 DNA nuclear import, allowing infection of non-dividing target cells. In one aspect, the presence of the DNA triplex sequence in an HIV vector strongly stimulates gene transfer in hematopoietic stem cells. The invention also provides methods of using these triplex structures for making recombinant cells, as well as methods of using the recombinant cells to express proteins of interest both in vitro and in vivo. | 01-08-2015 |
20140378652 | METHOD FOR PREPARING MULTIPLE ANTIGEN GLYCOPEPTIDE CARBOHYDRATE CONJUGATES - The present invention relates to a method for preparing carbohydrate T cell epitope conjugates of formula (I): M(T-B) | 12-25-2014 |
20140370678 | METHOD FOR PRODUCING A CONDUCTIVE NANOPARTICLE MEMORY DEVICE - A method for producing a memory device with nanoparticles, comprising the steps of:
| 12-18-2014 |
20140363663 | CMC MATERIAL PART - A part made of ceramic matrix composite material has fiber reinforcement of carbon or ceramic fibers and a majority-ceramic sequenced matrix having first matrix layers made of crack-deflector material alternating with second matrix layers made of ceramic material. An interphase coating is interposed between the fibers and the matrix, and the interphase coating adheres to the fibers and to the matrix, and is formed of at least one sequence constituted by a first elementary layer made of carbon, possibly doped with boron, surmounted by a second elementary layer made of ceramic. The outer elementary interphase layer of the coating is a ceramic layer having an outer surface formed by ceramic grains of size lying essentially in the range 20 nm to 200 nm, with the presence of grains of size greater than 50 nm conferring roughness on the outer surface ensuring mechanical attachment with the adjacent matrix phase. | 12-11-2014 |
20140354792 | ASSISTIVE DEVICE FOR POSITIONING A MEDICAL INSTRUMENT RELATIVE TO AN INTERNAL ORGAN OF A PATIENT - The invention relates to an assistive device for positioning a medical instrument ( | 12-04-2014 |
20140349330 | METHODS FOR AGGREGATION AND DIFFERENTIATION OF MAGNETIZED STEM CELLS - The invention relates to a process which enables optimal aggregation of cells, typically of stem cells, promoting the organisation thereof and advantageously the differentiation thereof, in particular in the context of the formation of a tissue substitute. This process comprises exposing pretreated cells to a magnetic field and makes it possible to obtain large cell aggregates, even prepared in the absence of support matrix and/or of growth factor. The invention also relates to the cell aggregates that can be obtained using such a process and also to the uses thereof as tissue initiators with a view to obtaining a tissue structure of interest in vitro, ex vivo or in vivo. Moreover, it relates to the resulting tissue structures and to the uses thereof in research or in therapy as tissue substitutes. The present application also provides a method which advantageously makes it possible to monitor the development of the tissue of interest in vivo. | 11-27-2014 |
20140347462 | QUANTITATIVE NONLINEAR OPTICAL MICROSCOPY USING A SHAPED BEAM - A nonlinear optical microscope is provided, including source of a pulsed laser beam; a spatial light modulator for modulating the spatial profile of the pulsed laser beam; an objective for guiding the modulated beam towards a slide intended to carry a specimen; and a detector for collecting signals originating from the specimen, wherein the spatial light modulator is designed to modulate the intensity and/or the phase of the pulsed laser beam on the rear pupil of the objective to produce a beam that is axially extended and confined in one or two lateral directions after focusing by the objective, and wherein the slide is placed on a motorized stage of a histology slide scanner assembly. | 11-27-2014 |
20140346901 | MINIATURE LINEAR VIBROTACTILE ACTUATOR - The invention relates to a miniature linear vibrotactile actuator comprising: a first element | 11-27-2014 |
20140342373 | MICROFLUIDIC SYSTEM - The present invention concerns a microfluidic system comprising: a microchannel containing several elements of two non-miscible fluids, the microchannel comprising a droplet ( | 11-20-2014 |
20140336373 | NOVEL COMPLEXING AGENTS AND CORRESPONDING LANTHANIDE COMPLEXES - The present invention concerns complexing agents of formula (I) in which a, b, c, chrom | 11-13-2014 |
20140336368 | MULTIMODAL CONTRAST AND RADIOPHARMACEUTICAL AGENT FOR AN IMAGING AND A TARGETED THERAPY GUIDED BY IMAGING - A multimodal contrast and radiopharmaceutical agent for an imaging and a targeted therapy guided by imaging. | 11-13-2014 |
20140333730 | METHOD OF 3D RECONSTRUCTION OF A SCENE CALLING UPON ASYNCHRONOUS SENSORS - A method of 3D reconstruction of a scene, including the implementation of at least two sensors each having a series of elementary receivers arranged so as to view the scene according to distinct respective solid angles and which are each sensitive to a physical characteristic of a signal received by the receiver originating from the scene. The sensors are adapted for emitting an asynchronous stream of events indicative of a modification of the signal received by one of the elementary receivers at a given instant, as well as the implementation of a 3D reconstruction algorithm having a step of pairing elementary receivers of each of the sensors utilizing signals generated by the sensors, the pairing including pairing between them events generated by each of the sensors and temporarily close together. | 11-13-2014 |
20140332729 | PROCESS FOR ENCAPSULATING AN INORGANIC PIGMENT BY POLYMERIZATION IN AN ORGANIC MEDIUM - The present invention relates to the field of inks for electrophoretic display devices, and more particularly to a process for encapsulating at least one inorganic pigment by dispersion polymerization in an organic medium. The process consists in dispersing the inorganic pigment in the organic medium, then in synthesizing at least one stable polymer latex in said organic medium, said latex precipitating around said inorganic pigment in order to form a protective shell and to thus obtain a particle, said synthesis of the latex being carried out by polymerization, in said organic medium, of an electrostatically chargeable functional monomer, based on use of a macroinitiator capable of stabilizing said particle obtained. | 11-13-2014 |
20140332717 | METHOD OF PRODUCING A SILICON/CARBON COMPOSITE MATERIAL AND USE OF SUCH A MATERIAL - A method of producing a silicon/carbon composite material which includes the following successive steps: providing a silicon/polymer composite material from silicon particles and a carbonaceous polymer compound, precursor of carbon and able to be cross-linked, performing at least partial cross-linking of the polymer of the silicon/polymer composite material so as to obtain a cross-linked silicon/polymer composite material, the polymer having a cross-linking rate greater than or equal to 50% and, pyrolysing the cross-linked silicon/polymer composite material until said silicon/carbon composite material is obtained. | 11-13-2014 |
20140330530 | METHOD AND DEVICE FOR DETERMINING A TRAJECTORY OF AN AQUEOUS FLOW, AND AUTONOMOUS PROBE IMPLEMENTED IN SAID METHOD - A method for determining a trajectory of an aqueous flow, implementing a mobile autonomous measurement device inserted into the aqueous flow, includes a step of measuring and a step of saving acceleration data in a reference base of the mobile device, and a step of processing data collected during the step of measuring to determine the trajectory by double integration of the processed data. | 11-06-2014 |
20140328753 | Antibodies for Molecular Imaging of Vulnerable Plaques in Atherosclerosis - Antibodies for molecular imaging of vulnerable plaques in atherosclerosis Antibody specifically binding to atherosclerosis lesions for in vivo imaging and methods for in vivo imaging of atherosclerosis lesions in a patient. | 11-06-2014 |
20140323671 | PROCESS FOR METATHESIS OF OLEFINS OBTAINED FROM FISCHER-TROPSCH FRACTIONS USING A RUTHENIUM COMPLEX COMPRISING A DISSYMMETRICAL N-HETEROCYCLIC DIAMINOCARBENE - This invention describes a process for metathesis of olefins from feedstocks obtained from the Fischer-Tropsch process, using as catalyst a ruthenium alkylidene complex comprising a saturated or unsaturated, dissymmetrical N-heterocyclic carbene (NHC) ligand. | 10-30-2014 |
20140322744 | CLONABLE TAG FOR CORRELATIVE LIGHT AND ELECTRON MICROSCOPY LABELING - The present invention relates to a new clonable label for Correlative Light and Electron Microscopy based on the combination of modified metallothionein and lanthanides. | 10-30-2014 |
20140318474 | METHOD AND DEVICE FOR VISUALLY SCARING ANIMAL SPECIES, IN PARTICULAR BIRD SPECIES - A device for visually scaring animal species, in particular bird species includes means for generating at least one visual signal including at least one image, varying in size over time, which simulates approach via an increase in the size of the image. For example, the visual signal includes one of the following images: eyes, a disc, and a spiral. | 10-30-2014 |
20140318368 | Discontinuous Regime Membrane Separation Process - A process for separating a gaseous or liquid mixture by means of a separating device including a first volume (V | 10-30-2014 |
20140308298 | Diagnostic and Treatment of an Androgen-Independent Prostate Cancer - The present invention relates to a method for monitoring the tumor growth of an androgen-independent prostate cancer in a subject, by determining the amount of at least one adrenomedullin receptor and optionally adrenomedullin in a prostate cancer cell obtained from said subject. The present invention also relates to a pharmaceutical composition comprising an anti-adrenomedullin antagonist antibody and/or at least one anti-adrenomedullin receptor antagonist antibody for treating an androgen-independent prostate cancer. | 10-16-2014 |
20140302498 | RAPID DETECTION OF THE "HIGH VIRULENT" ST-17 CLONE OF GROUP B STREPTOCOCCUS - The present invention relates to polynucleotides enabling the rapid, simple and specific detection of Group B | 10-09-2014 |
20140302324 | MRI-VISIBLE HYDROPHOBIC COPOLYMER - The invention relates to a hydrophobic thermoplastic copolymer which is in particular of use for manufacturing and/or coating medical devices, in particular implantable medical devices, characterized in that it is obtained by copolymerization, and in that it comprises at least one first monomer unit and at least one second monomer unit onto which is grafted a paramagnetic-ion-chelating ligand which can complex with such a paramagnetic ion or a paramagnetic-ion-chelating ligand which is complexed with such a paramagnetic ion, wherein the second monomer unit is grafted in sufficient amount for the copolymer to be visible in magnetic resonance imaging when it is complexed with said paramagnetic ion. The invention also relates to a method for obtaining said hydrophobic thermoplastic copolymer. | 10-09-2014 |
20140301997 | COMPOSITION FOR A MITOTIC REMODELING OF CHROMOSOMES - A composition of a female germinal cell (egg) extract of pluricellular organisms in M-phase of the cell cycle, the extract being used for a mitotic remodeling of chromosomes of donor cells of pluricellular organisms, wherein the mitotic remodeling confers to the nucleus of the donor cells the ability to adapt themselves to the early embryonic development, in particular to the replication phases, in order to carry out the embryonic development or to obtain stem cells. | 10-09-2014 |
20140299835 | RAM MEMORY POINT WITH A TRANSISTOR - A memory cell formed of a semiconductor nanorod having its ends heavily doped to form source and drain regions and having its central portion comprising, between the source and drain regions, an N-type region surrounded on a majority of its periphery with a quasi-intrinsic P-type region, and wherein the P-type region itself is surrounded with an insulated gate. | 10-09-2014 |
20140296876 | DEVICE FOR GUIDING A MEDICAL INSTRUMENT INSERTED INTO A NATURAL DUCT OR AN ARTIFICAL DUCT OF A PATIENT - The invention relates to a device for guiding a medical instrument ( | 10-02-2014 |
20140296288 | IMINO-SUGAR C-GLYCOSIDES, PREPARATION AND USE THEREOF - The present disclosure relates to iminosugar derivatives and processes for the preparation thereof. The disclosed compounds have glycosidase inhibiting properties, and are useful in the treatment of various diseases, such as type 2 diabetes, neurodegenerative diseases or lysosomal storage disorders. The present disclosure also relates to pharmaceutical compositions containing the disclosed compounds and to their use as biochemical tools. | 10-02-2014 |
20140294880 | MUTATED LENTIVIRAL ENV PROTEINS AND THEIR USE AS DRUGS - A pharmaceutical composition includes, as active substance a mutated lentiviral ENV protein, substantially devoid of immunosuppressive properties or a variant of the mutated lentiviral ENV protein or a fragment of the above proteins, in association with a pharmaceutically acceptable carrier. | 10-02-2014 |
20140291572 | METHOD FOR PREPARING ALKALI METAL AND TRANSITION METAL FLUOROSULFATES - The invention relates to a method for preparing an alkali metal and transition metal fluorosulfate that is useful as an electrode material in an electrochemical battery that operates by alkali ion exchange. The method includes a first step that involves: preparing a mixture of precursors of elements making up fluorosulfate, placing said mixture in contact with a solid polymer at ambient temperature, subjecting the reaction medium to a heat treatment that aims to melt the polymer, and subsequently reacting the precursors with one another. Said polymer is one that is solid at ambient temperature, has a melting point lower than the reaction temperature of the precursors, is stable at least up to the reaction temperature of the precursors, and is soluble in a nonpolar aprotic organic solvent. | 10-02-2014 |
20140290745 | USE OF COBALT COMPLEXES FOR PREPARING AN ACTIVE LAYER IN A PHOTOVOLTAIC CELL, AND CORRESPONDING PHOTOVOLTAIC CELL - A method for employing certain cobalt complexes as electron donors and in combination with an electron acceptor is provided for preparing an active layer in a photovoltaic conversion cell, as well as to the photovoltaic conversion cell in which the electron donor of the active layer includes such cobalt complexes. | 10-02-2014 |
20140290376 | RESISTIVE DEVICE COMPRISING A SILICON-NANOWIRE-COMPRISING STRAIN GAUGE AND METHOD FOR OPTIMIZING THE ELECTRICAL CONSUMPTION OF SUCH A DEVICE - A resistive device includes at least one strain gauge ( | 10-02-2014 |
20140288120 | COMPOUNDS USEFUL FOR TREATING AIDS - A compound having the following formula or a pharmaceutically acceptable salt thereof: | 09-25-2014 |
20140287989 | Compounds Binding to the Bacterial Beta Ring - The present invention relates to compounds which bind to the hydrophobic pocket of the β clamp, i.e., to the surface of the β ring with which said protein interacts with other proteins of the bacterial replication complex during DNA replication. These compounds are derived from the acetylated peptide AcQLDLF (P6) to improve their affinity to their target. | 09-25-2014 |
20140287912 | Process for Preparing a Monolithic Catalysis Element Comprising a Fibrous Support and Said Monolithic Catalysis Element - A process for preparing a monolithic catalysis element includes a fibrous support and a catalytic phase supported by the fibrous support and also the monolithic catalysis element. The process includes the steps of preparing a porous coherent structure based on refractory fibers; preparing a substrate including the porous coherent structure and nanocarbon supported by the porous coherent structure in the body thereof; and grafting to the substrate, by π interaction, of at least one aromatic compound containing in its chemical formula, at least one aromatic ring, and at least one function chosen from acid catalytic functions, basic catalytic functions, metallic precursor functions, functions that can be converted in situ into metallic precursor functions, and mixtures thereof. | 09-25-2014 |
20140269003 | MEMORY CELL WITH VOLATILE AND NON-VOLATILE STORAGE - The invention concerns a non-volatile memory element comprising: first and second transistors ( | 09-18-2014 |
20140266291 | METHOD, DEVICE AND SYSTEM FOR AUTOMATIC DETECTION OF DEFECTS IN TSV VIAS - A method for automatic detection of defects in TSV vias formed in a layer of semiconductor material, this detection taking place before stacking this layer with a plurality of other layers of semiconductor material for the design of a multilayer chip integrated circuit, comprising: measurement on each of said TSV vias of at least one parameter derived from an electrical characteristic of the TSV vias; detection of defects in said TSV vias according to a comparison of the parameters measured with at least one reference parameter, and calculation of said at least one reference parameter using the measured parameters. The parameter measured on each of the TSV vias comprises an oscillation frequency value derived from a capacitive characteristic of the TSV vias. | 09-18-2014 |
20140255339 | COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF VIRAL INFECTIONS - Provided herein are compounds, compositions and methods for the treatment of liver disorder, including HCV and/or HBV infections. Specifically, compound and compositions of nucleoside derivatives are disclosed, which can be administered either alone or in combination with other anti-viral agents. | 09-11-2014 |
20140253094 | METHOD FOR THE RAPID INTERROGATION OF A PASSIVE SENSOR, IN PARTICULAR OF THE SURFACE ACOUSTIC WAVES TYPE, AND SYSTEM FOR MEASURING THE UNIQUE FREQUENCY OF SUCH A SENSOR - For passive sensor with resonator having a natural frequency, a method comprises: a first phase emission of an electromagnetic signal toward the passive sensor at an emission frequency, the resonator oscillating in a forced regime at the emission frequency and then oscillating at its natural frequency when the emission is cut off; a first phase reception of the damped signal oscillating at natural frequency emitted by passive sensor, a measurement of the frequency being performed; a second phase emission of an electromagnetic signal at the measured frequency toward the passive sensor, the resonator oscillating in a forced regime at the measured frequency and then oscillating at its natural frequency when the emission is cut off; a second phase reception of the damped signal oscillating at natural frequency, a measurement of the frequency being performed, determination of the natural frequency being stopped due to measurement performed in this second reception phase. | 09-11-2014 |
20140252686 | METHOD FOR DETECTING THE PRESENCE OF BUBBLES DURING OPERATIONS OF INJECTING RESIN FOR THE MANUFACTURE OF FIBRE COMPOSITE COMPONENTS - A method of detecting bubbles during operations for injecting resin for the manufacture of fibre composite components, is noteworthy in that the electrical capacitance or conductivity of at least one part of the medium formed by the fibres and the liquid is measured. | 09-11-2014 |
20140248306 | LENTIVIRAL GENE TRANSFER VECTORS AND THEIR MEDICINAL APPLICATIONS - The present invention relates to the design of gene transfer vectors and especially provides lentiviral gene transfer vectors suitable for either a unique administration or for iterative administration in a host, and to their medicinal application (such as vaccination against Immunodeficiency Virus, especially suitable in human hosts). Gene transfer vectors can be either integrative or non-integrative vectors. The invention encompasses prophylactic, therapeutic, symptomatic, and curative treatments of animals, including humans, as well as gene therapy and vaccination in vivo. | 09-04-2014 |
20140243499 | PEPTIDE DERIVATIVES AND USE THEREOF AS CARRIERS FOR MOLECULES IN THE FORM OF CONJUGATES - The invention relates to peptide derivatives (peptides and pseudo-peptides) and use thereof as vectors for molecules of interest. The invention also relates to conjugates containing a peptide derivative of the invention bound to a molecule of interest. The peptides and prodrug conjugates of the invention can be used to vectorise molecules of pharmaceutical or diagnostic interest, such as, for example, therapeutic molecules, imaging or diagnostic agents, or molecular probes, across cell membranes, and notably to promote their transport across the blood-brain barrier (BBB). | 08-28-2014 |
20140243391 | PHOSPHOLIPID-DETERGENT CONJUGATES AND USES THEREOF - The invention relates to novel compounds, in particular novel O-substituted phospholipids that are useful for the in vitro and in vivo delivery of drugs as well as nucleic acids into cells. The invention also relates to pharmaceutical compositions and supramolecular complexes comprising said compounds and the use of these compounds in therapeutic treatment, in particular in gene therapy. | 08-28-2014 |
20140242784 | METHOD FOR FORMING A GRAPHENE LAYER ON THE SURFACE OF A SUBSTRATE INCLUDING A SILICON LAYER - The invention relates to a method for forming a graphene layer ( | 08-28-2014 |
20140242146 | FILAMENT BASED ON HYALURONIC ACID IN THE FORM OF FREE ACID AND METHOD FOR OBTAINING IT - The present invention relates to a method for preparing by wet spinning a continuous filament based on hyaluronic acid in free acid form, notably soluble in water. The preparation method according to the invention comprises the following steps: a) preparing a spinnable aqueous solution of hyaluronic acid or of a hyaluronic acid salt, preferably a sodium hyaluronate solution; b) extruding said solution to an extrusion die; c) forming the filament by passing the extruded solution into a bath of acetic acid, concentrated to more than 80%, drawing and drying. The invention also relates to a filament based on hyaluronic acid in free acid form, said filament having swelling properties in water and physiological liquids and moreover being solubilizable in water under certain conditions. | 08-28-2014 |
20140242076 | MULTISPECIFIC MUTATED ANTIBODY FAB FRAGMENTS - The invention relates to multispecific antibody constructs comprising Fab fragments having mutations at the interface of the CH1 and CL domains, said mutations preventing heavy/light chain mispairing. | 08-28-2014 |
20140238117 | Determination of interfacial tensions in supercritical conditions - The invention concerns a method whereby: (E1) an inner liquid phase is made to flow in an inner flow member, and an outer liquid phase in an outer flow member, the flow of the inner liquid phase opening within the flow of the second liquid phase; and the temperature and pressure in the contact area between the first and second liquid phases being such that the first and/or second liquid phase is in the supercritical state, (E2) the flow rate of the inner phase and/or outer phase is varied in such a way as to modify the flow profile, and a torque is identified from values of the flow rates of the inner and outer phases, called transition flow rates, from which the modification in the flow profile occurs (from drops to a jet; or from a jet to drops); (E3 ) from the transition torque identified in step (E2), the value of the interfacial tension between the two inner and outer liquid phases is calculated, or the result obtained is compared to that obtained for another torque in the conditions of steps (E1) and (E2). | 08-28-2014 |
20140236313 | MICROSTRUCTURED ADHESION SUBSTRATE FOR ANIMAL OR HUMAN CELLS - The present invention relates to an adhesion substrate for at least one animal or human cell on the surface of which is generated an adhesion pattern for at least one animal or human cell, said pattern including at least two areas adhering to said cell, which are spaced apart by an area not adhering to said cell on which a polymer not adhering to said cell is immobilized, characterized in that the polymer is selected so as to have a conformation which may be modified by varying a parameter of the environment in which the substrate is found, to a method for preparing such a substrate and to the cell analysis methods using such a substrate. | 08-21-2014 |
20140235654 | USE OF DERIVATIVES OF INDOLES FOR THE TREATMENT OF CANCER - The present invention relates to the use of derivatives of indoles having a general formula (I) as follow: | 08-21-2014 |
20140234342 | NKP46-MEDIATED NK CELL TUNING - The present invention relates to compounds (e.g. antibodies) that specifically bind and inhibit NKp46. Such compounds are capable, when administered to a mammal, capable of increasing the frequency of reactive and/or active NK cells. The invention also relates to pharmaceutical composition and methods of using the antibodies and compositions to treat or prevent diseases, e.g. cancer, infection, autoimmune diseases, inflammatory diseases and the like. | 08-21-2014 |
20140233900 | Microstructured Optical Fibre Having A Large Core And A Flattened Fundamental Mode, Production Method Thereof And Use Of Same In Laser Microfabrication - The fibre comprises a core ( | 08-21-2014 |
20140231310 | PROCESS FOR HYDRODESULPHURATION OF GASOIL CUTS USING A CATALYST BASED ON HETEROPOLYANIONS TRAPPED IN A MESOSTRUCTURED SILICA SUPPORT - The invention relates to a process of hydrodesulphuration of at least one gasoil cut implementing a catalyst containing, in its oxide form, at least one metal from group VIB and/or at least one metal from group VIII of the periodic table, present in the form of at least one polyoxometalate of the formula (H | 08-21-2014 |
20140230912 | DEVICE FOR HANDLING OBJECTS, USING ACOUSTIC FORCE FIELDS - The invention relates to a device ( | 08-21-2014 |
20140221450 | Compositions for the treatment of Fragile X syndrome - The present invention relates to a composition comprising a maxi-K potassium channel opener the use in the treatment of fragile X syndrome. More specifically the present invention relates to a composition comprising a fluoro-oxindole or a chloro-oxindole for use in the treatment of fragile X syndrome. | 08-07-2014 |
20140221289 | Thixotropic A-Lactalbumin Hydrogels, Method for Preparing Same and Uses Thereof - The present invention relates to shear-thinning α-lactalbumin hydrogels, which have a threshold and are thixotropic, to a method for preparing same and to the use thereof. | 08-07-2014 |
20140221205 | ACTINOMYCETE STRAIN COMPOSITION AND ITS USE - Novel actinomycete strain composition and its use. | 08-07-2014 |
20140220599 | DIAGNOSIS METHOD OF ACTIVE TUBERCULOSIS - The present invention relates to a method for the in vitro diagnosis of active tuberculosis, comprising a step of contacting lymphocytes of a patient suspected to have active tuberculosis with at least one protein of mycobacteria, said protein being an enzyme having a lipolytic activity, and a step of detecting the presence of specific activated lymphocytes. | 08-07-2014 |
20140213540 | MODIFIED 2' AND 3'-NUCLEOSIDE PRODRUGS FOR TREATING FLAVIVIRIDAE INFECTIONS - 2′ and/or 3′ prodrugs of 1′, 2′, 3′ or 4′-branched nucleosides, and their pharmaceutically acceptable salts and derivatives are described. These prodrugs are useful in the prevention and treatment of Flaviviridae infections, including HCV infection, and other related conditions. Compounds and compositions of the prodrugs of the present invention are described. Methods and uses are also provided that include the administration of an effective amount of the prodrugs of the present invention, or their pharmaceutically acceptable salts or derivatives. These drugs may optionally be administered in combination or alteration with further anti-viral agents to prevent or treat Flaviviridae infections and other related conditions. | 07-31-2014 |
20140207150 | ENDOSCOPIC INSTRUMENT WITH SUPPORT FOOT - The invention relates to an endoscopic instrument ( | 07-24-2014 |
20140206690 | COMPOUNDS FOR USE AS THERAPEUTIC AGENTS AFFECTING P53 EXPRESSION AND/OR ACTIVITY - The present invention relates to compound (I) | 07-24-2014 |
20140206081 | VARIABLE DOMAINS OF CAMELID HEAVY-CHAIN ANTIBODIES DIRECTED AGAINST GLIAL FIBRILLARY ACIDIC PROTEINS - The present invention relates to the use of variable domains of camelid heavy-chain antibodies (VHH domains) directed against an intracellular target and having an isoelectric point of at least 8.5, for targeting said intracellular target or for the preparation of a peptide vector. Particularly, it concerns VHH domains directed against a glial fibrillary acidic protein and uses thereof for preparing therapeutic or diagnostic agents. | 07-24-2014 |
20140200161 | METHOD OF PREPARING AN ADDUCT - A method for identifying one or several molecular structure(s) having a high-affinity for a target of interest, the molecular structure(s) each including one nucleotide chain onto which is hybridized at least one PNA-encoded molecule. | 07-17-2014 |
20140199746 | ELECTROKINETIC CONFINEMENT OF NEURITE GROWTH FOR DYNAMICALLY CONFIGURABLE NEURAL NETWORKS - Systems and methods for altering neurite growth are generally described. In some embodiments, a system may include a neuron comprising a neurite and electrodes able to generate a physical guidance cue. The physical guidance cue may be used to alter the growth of the neurite and may be temporally and spatially dynamic, such that neurite growth may be altered in a spatial and/or temporal manner. Dynamic control of neurite growth may be used to form directional neural connections, intersections, and/or overlaps. | 07-17-2014 |
20140199745 | ELECTROKINETIC CONFINEMENT OF NEURITE GROWTH FOR DYNAMICALLY CONFIGURABLE NEURAL NETWORKS - Systems and methods for altering neurite growth are generally described. In some embodiments, a system may include a neuron comprising a neurite and electrodes able to generate a physical guidance cue. The physical guidance cue may be used to alter the growth of the neurite and may be temporally and spatially dynamic, such that neurite growth may be altered in a spatial and/or temporal manner. Dynamic control of neurite growth may be used to form directional neural connections, intersections, and/or overlaps. | 07-17-2014 |
20140199379 | COMPOSITIONS HAVING MEANS FOR TARGETING AT LEAST ONE ANTIGEN TO DENDRITIC CELLS - A composition that can be used as a vaccine containing means for targeting at least one antigen to dendritic cells and as adjuvants a granulocyte macrophage colony stimulating factor and a CpG oligodeoxynucleotide and/or a CpG-like oligodeoxynucleotide. This composition can used to treat cancers, infectious diseases caused by bacterial, viral, fungal, parasitic or protozoan infections, allergies and/or autoimmune diseases. | 07-17-2014 |
20140199243 | BIFUNCTIONAL PHOSPHONATE CHELATING AGENTS - Compounds of the following Formula (I): | 07-17-2014 |
20140193322 | RIGID FOAMS BASED ON PROCYANIDIN- AND/OR PRODELPHINIDIN-TYPE TANNINS AND PREPARATION METHOD THEREOF - Use of at least one procyanidin- and/or prodelphinidin-type tannin, devoid of prorobinetidin- and/or profisetinidin-type tannin, in a mixture with furfuryl alcohol for the implementation of a polymerization reaction for the preparation of rigid foams, said procyanidin- and/or prodelphinidin-type tannin being in particular pine bark tannin. | 07-10-2014 |
20140186944 | USE OF CELLULAR EXTRACTS FOR OBTAINING PLURIPOTENT STEM CELLS - The use of a composition including at least one permeabilized nucleus of a first cell, or at least one permeabilized first cell including the nucleus and an extract of female germinal cells, or eggs, of a multicellular organism, the eggs being blocked in the metaphase II of meiosis, the extract including EGTA, for carrying out a method for obtaining pluripotent stem cells, or tissues derived from the pluripotent stem cells, or of cloning, provided that the process is not for cloning human beings. | 07-03-2014 |
20140179679 | MOLECULES INHIBITING A METABOLIC PATHWAY INVOLVING THE SYK PROTEIN TYROSINE KINASE AND METHOD FOR IDENTIFYING SAID MOLECULES - The present invention relates to the C-13 molecule (methyl 2-{5-[(3-benzyl-4-oxo-2-thioxo-1,3-thiazolidin-5-ylidene)methyl]-2-furyl}-benzoate) and to organic molecules functionally equivalent to the C-13 molecule, capable of inhibiting the binding of an antibody or antibody fragment with the human Syk protein tyrosine kinase, to the use of these molecules for the production of medicaments for the prevention or treatment of diseases dependent on metabolic pathways involving Syk, and also to a method for identifying such molecules. | 06-26-2014 |
20140178384 | POST-TRANSLATIONALLY MODIFIED NEUROTROPHINS - The present invention describes that neurotrophins undergo post-translational modifications, and that these post-translational modifications mediate the pro-apoptotic and/or pro-neurite activity of neurotrophins. These post-translational modifications notably include nitration and the formation of conformationally-different dimers, as well as of abnormal oligomers, such as tetramers and octamers. The invention further relates to compounds that compete with such modified neurotrophins, as well as to compounds that binds to said modified neurotrophins. The invention thus provides useful agents for the treatment of the conditions or diseases involving chronic pain and/or neuron loss. | 06-26-2014 |
20140171676 | METHOD FOR PREPARING ACROLEIN FROM GLYCEROL OR GLYCERINE - A method of preparing acrolein from glycerol or glycerine is disclosed. The method includes dehydrating glycerol or glycerine in the presence of a catalyst consisting of at least (a) a mixed oxide of zirconium and at least one metal, said metal being selected from niobium, tantalum and vanadium, or (b) a zirconium oxide and at least one metal oxide, the metal being selected from niobium, tantalum and vanadium, or (c) a silicon oxide and a mixed oxide of zirconium and at least one metal, the metal being selected from tungsten, cerium, manganese, niobium, tantalum, titanium, vanadium and silicon, or (d) a titanium oxide and a mixed oxide of zirconium and at least one metal, said metal being selected from tungsten, cerium, manganese, niobium, tantalum, titanium, vanadium and silicon. | 06-19-2014 |
20140168801 | COLLECTOR MIRROR FOR A SOLAR CONCENTRATOR COMPRISING LINEAR FRESNEL MIRRORS - The invention relates to a collector mirror ( | 06-19-2014 |
20140167816 | MEMORY CELL WITH VOLATILE AND NON-VOLATILE STORAGE - The invention concerns a memory device comprising at least one memory cell comprising: first and second pairs of cross-coupled transistors; and a first resistance switching element ( | 06-19-2014 |
20140163216 | COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF VIRAL INFECTIONS - Provided herein are compounds, compositions and methods for the treatment of liver disorders, including HCV infections. In one embodiment, compounds and compositions of nucleoside derivatives are disclosed, which can be administered either alone or in combination with other anti-viral agents. | 06-12-2014 |
20140162301 | Method for Classifying the Presence or Absence of a Microorganism in a Biological Medium - The present invention relates to a method for determining the presence or absence of a microorganism, said method including the steps of: 1) providing an enclosure containing a liquid or semi-solid phase consisting of a biological medium capable of containing a living form of said microorganism, nutritional elements, and an enzymatic substrate which is specific to said microorganism and which can be metabolised into at least one VOC metabolite, and a gaseous phase adjacent to said liquid or semi-solid phase; 2) exposing at least said liquid or semi-solid phase to conditions that are propitious for said microorganism to metabolise said enzymatic substrate into a molecule of said VOC metabolite; and 3) determining, by optical transduction, the presence or absence of said VOC metabolite, characterised in that the latter interacts with a nanoporous matrix, said matrix being implemented in a form that is separate from said enzymatic substrate, and in that the detection, by optical transduction, of a change in the optical properties of said matrix indicates an interaction of said matrix with said metabolite. | 06-12-2014 |
20140161793 | GLYCOCONJUGATES AND THEIR USE AS POTENTIAL VACCINES AGAINST INFECTION BY SHIGELLA FLEXNERI - A conjugate molecule comprising an oligo- or polysaccharide covalently bound to a carrier and its use as potential vaccine against infection by | 06-12-2014 |
20140157887 | Miniaturised Sensor Comprising A Heating Element, And Associated Production Method - The invention relates to a miniaturised sensor having a heating element, and to an associated production method. The sensor includes a substrate, a cavity and a heat-insulating structure suspended above the cavity by areas connecting to the substrate. The heat-insulating structure includes at least two bridges extending above the cavity, the heating element being supported by said bridges, extending transversely thereto. | 06-12-2014 |
20140145715 | DEVICE AND METHOD FOR CHARACTERIZING A LASER BEAM - A device and a method making it possible to measure a magnetization generated within an active medium, or to characterize a linearly polarized electromagnetic wave when said active medium exhibits an Inverse Cotton-Mouton effect, comprises in combination at least the following elements: an active medium in which a linearly polarized electromagnetic wave propagates, a means for producing a transverse magnetic field with respect to the direction of propagation of said electromagnetic wave, a device for measuring the electrical signal suitable for manifesting the magnetization generated within said active medium by said electromagnetic wave. | 05-29-2014 |
20140140365 | SENSOR FOR DIFFERENTIAL CALORIMETRIC MEASUREMENT, AND METHOD FOR MANUFACTURING SAME - A sensor for differential calorimetric measurement including a thermometric cell and another cell, each cell including: a membrane of a low thermal conductivity material, having first and second surfaces; and a mechanism supporting the membrane, of a high thermal diffusivity coefficient material, in contact with the first surface of the membrane, the thermometric cell including at least two active thermometric elements located on the first surface of the membrane, the two cells configured to be assembled such that the second surfaces of the membranes of the cells are opposite one another, a sample and a reference used for taking measurement configured to be placed between the two membranes and directly in contact with the second surfaces, and at least one of the cells including a sealing mechanism opposite the first surface of the membrane, wherein a free space for a gas is arranged between the sealing mechanism and the membrane. | 05-22-2014 |
20140130850 | COMPOSITION OF AN ORGANIC PHOTOVOLTAIC CELL OF A PHOTOVOLTAIC MODULE - A composition of an active film of an organic photovoltaic cell, including: an electron-donor material having a conjugated polymer; and an electron-acceptor material having a polymer, wherein the active film comprises a copolymer with a linear structure including: two to five blocks, at least two blocks of which have different chemical natures; two consecutive blocks having different chemical natures; each block having a molar mass of between 500 g/mol and 50,000 g/mol. Also, an organic-cell-based photovoltaic module incorporating such a composition and the use of this composition for the same purposes. | 05-15-2014 |
20140130482 | Device for the Purification of Exhaust Gases from a Heat Engine, Comprising a Ceramic Carrier and an Active Phase Mechanically Anchored in the Carrier - Device for the purification of exhaust gases from a thermal combustion engine comprising: | 05-15-2014 |
20140128335 | USE OF POLYAMINOISOPRENYL DERIVATIVES IN ANTIBIOTIC OR ANTISEPTIC TREATMENT - The present invention relates to the use of polyaminoisoprenyl derivatives in antibiotic or antiseptic treatment of bacteria including those presenting multiple drug resistance (MDR), in particular as efflux pump inhibitors. It also relates to novel polyaminoisoprenyl derivatives, compositions comprising the same, process for preparing the same, and use thereof in antibiotic or antiseptic treatment. | 05-08-2014 |
20140127099 | Device for Purifying Exhaust Gases from a Heat Engine, Comprising a Catalytic Ceramic Support Comprising an Arrangement of Essentially Identical Crystallites - Device for purifying exhaust gases from a thermal combustion engine, comprising a catalytic ceramic carrier comprising an arrangement of crystallites of the same size, same isodiametric morphology and same chemical composition or substantially the same size, same isodiametric morphology and same chemical composition, wherein each crystallite is in contact at a singular or almost singular point with surrounding crystallites, and whereon at least one active phase is deposited for the chemical destruction of impurities in the exhaust gas. | 05-08-2014 |
20140121238 | TOTAL SYNTHESIS OF REDOX-ACTIVE 1.4-NAPHTHOQUINONES AND THEIR METABOLITES AND THEIR THERAPEUTIC USE AS ANTIMALARIAL AND SCHISTOMICIDAL AGENTS - Naphthoquinones, azanaphthoquinones and benxanthones, their process of synthesis and methods of their use as antimalarial or antischistosomal agents. | 05-01-2014 |
20140120566 | Bilirubin Oxidase from Magnaporthe Oryzae and Applications Thereof - The present invention relates to a novel bilirubin oxidase from | 05-01-2014 |
20140120014 | Device for the Purification of Exhaust Gases from a Heat Engine, Comprising a Ceramic Carrier and an Active Phase Chemically and Mechanically Anchored in the Carrier - Device for the purification of exhaust gases from a thermal combustion engine comprising: | 05-01-2014 |
20140118811 | METHOD AND SYSTEM FOR CONFIGURING A DEVICE FOR CORRECTING THE EFFECT OF A MEDIUM ON A LIGHT SIGNAL, METHOD, DEVICE AND SYSTEM FOR CORRECTING SAID EFFECT - A method and a system is provided for configuring a device for correcting the effect of a medium on a light signal having propagated through the medium, the device including at least one optical element whose phase profiles are individually adjustable. The configuring system and method include propagating a reference signal and a disordered signal obtained at the output of the medium through the correcting device. An interference parameter is measured and optimized by modifying the phase profile of each of the optical elements of the correcting device. A method and a system is also provided for correcting the effect of a medium on a light signal having propagated through the medium. | 05-01-2014 |
20140118724 | Analyseur Spatial de Faisceau Laser a Reglage Automatique - An analyzer of the spatial intensity distribution of a laser beam focused or transmitted by an optical fiber comprises: a shaping lens; a device for taking a partial sample of the beam; a heat sink; a photodiode; an imaging lens to form images of the plane on an image sensor; a motorization of the shaping lens to translate along the optical axis; a motorization of the imaging lens to translate in a plane perpendicular to the optical axis; a motorization of the image sensor to translate along the optical axis; an electronic unit controlling each motorization; an electronic unit synchronizing the image sensor, connected to the photodiode to synchronize image capture with the laser pulses or in the pulses; an electronic unit adjusting the aperture and/or gain of the image sensor; and a software interface parameterizing and piloting the electronic control units, equipped with an image processing unit. | 05-01-2014 |
20140113285 | MUTATION WITHIN THE CONNEXIN 26 GENE RESPONSIBLE FOR PRELINGUAL NON-SYNDROMIC DEAFNESS AND METHOD OF DETECTION - A purified polynucleotide having a chain of nucleotides corresponding to a mutated sequence, which in a wild form encodes a polypeptide implicated in hereditary sensory defect, wherein said mutated purified polynucleotide presents a mutation responsible for prelingual non-syndromic deafness selected from the group consisting of a specific deletion of at least one nucleotide. | 04-24-2014 |
20140113215 | SPECIFIC PHOSPHONATED COPOLYMERS AND INORGANIC PARTICLES GRAFTED BY SAID COPOLYMERS - The invention relates to copolymers comprising a chain of siloxane repeat units of at least two different types, a first type of siloxane repeat unit comprising at least one —OH group on the silicon atom of the siloxane repeat unit and a second type of repeat unit comprising at least one pendant chain on the silicon atom of said repeat unit, this pendant chain consisting of a polymer chain comprising a chain of repeat units carrying at least one group of formula —PO | 04-24-2014 |
20140107186 | CAPSID-FREE AAV VECTORS, COMPOSITIONS, AND METHODS FOR VECTOR PRODUCTION AND GENE DELIVERY - An isolated linear nucleic acid molecule comprising in this order: a first adeno-associated virus (AAV) inverted terminal repeat (ITR), a nucleotide sequence of interest and a second AAV ITR, wherein said nucleic acid molecule is devoid of AAV capsid protein coding sequences. The said nucleic acid molecule can be applied to a host at repetition without eliciting an immune response. Methods for producing and purifying this nucleic acid molecule, and use of the same for therapeutic purposes are also provided. | 04-17-2014 |
20140106436 | USE OF AT LEAST ONE CHELATING AGENT INTRODUCED INTO THE CULTURE MEDIUM OF MAGNETOTACTIC BACTERIA IN ORDER TO STIMULATE THE GROWTH THEREOF - The invention relates to the use of at least one chelating agent, including an iron chelating agent, in order to stimulate the growth of magnetotactic bacteria. | 04-17-2014 |
20140090973 | DEVICE AND METHOD FOR ION BEAM SPUTTERING - The invention relates to a device for depositing a selected material on a substrate by means of ion beam sputtering, which include a plurality of targets of a selected material, each of which is bombarded by an ion beam, the lateral dimensions of each of the ion beams being less than one tenth of the lateral dimensions of the substrate. | 04-03-2014 |
20140087378 | METHOD, PROBE AND KIT FOR DNA IN SITU HYBRIDATION AND USE THEREOF - The invention relates to a method for the detection of the occurrence of initiation of replication events in genomic DNA in a eukaryotic cell, involving contacting said eukaryotic cell comprising said genomic DNA with a first nucleotide probe, under conditions enabling in situ hybridization of said first nucleotide probe with a target region in the DNA genome, wherein said target region comprises a nucleic acid sequence which has no identified corresponding annealing RNA in a metabolically active cell and therefore remains RNA-free during transcription and replication of said DNA genome and detecting said first nucleotide probe hybridized to said DNA. Further detection of at least one RNA molecule can be achieved. The invention also relates to a nucleic acid molecule suitable for use as a probe, hybridizing with a target region in a eukaryotic genomic DNA, and comprising a nucleic acid sequence which has no identified corresponding annealing RNA in the metabolically active cell containing said eukaryotic genomic DNA and therefore remains RNA-free during transcription and replication of said DNA genome. The invention also encompasses kit(s) for carrying out in situ hybridization and use of the method(s), nucleic acid molecule(s) or kit(s) of the invention in the detection of mitochondrial disease(s), neoplasic diseases(s) or cancer(s), or in the testing of the cytotoxicity of organic or chemical compounds, especially drugs, on eukaryotic cells. | 03-27-2014 |
20140083500 | COMPOSITION FOR AN ACTIVE LAYER OR ELECTRODE OF PHOTOVOLTAIC CELLS - A composition including a graft copolymer, having: a linear trunk including at least one non-aromatic vinyl polymer or an unsaturated polyolefin; and at least two grafts attached to said trunk via a chemical bond, each graft having a conjugated polymer, characterized in that said composition further includes: fullerenes and a conjugated polymer; or carbon and/or graphene nanotubes. Also, a photovoltaic module incorporating such a composition, and to the use of said composition for the same purposes. Finally, methods for synthesizing the molecules forming all or part of the composition. | 03-27-2014 |
20140080206 | MICROFLUIDIC SYSTEM FOR CONTROLLING A CONCENTRATION PROFILE OF MOLECULES CAPABLE OF STIMULATING A TARGET - The invention relates to a microfluidic system for controlling a concentration profile of molecules capable of stimulating a target, for example formed by an assembly of living cells, this system comprising: -a microfluidic device ( | 03-20-2014 |
20140078810 | LOADLESS VOLATILE/NON-VOLATILE MEMORY CELL - The invention concerns a memory device comprising at least one memory cell comprising: first and second transistors ( | 03-20-2014 |
20140073637 | AMINO-SUBSTITUTED-ALKYLOXY-BENZO[E]PYRIDO[4,3-B]INDOLE DERIVATIVES AS NEW POTENT KINASE INHIBITORS - The present invention relates to a new class of benzo[e]pyrido-indole, the amino-substituted-alkyloxy-benzo[e]pyrido[4,3-b]indole derivatives, having a particular kinase inhibition profile and useful as a therapeutic agent, in particular an anti-tumoral agent. | 03-13-2014 |
20140073633 | INHIBITORS OF THE SHIGA TOXINS TRAFFICKING THROUGH THE RETROGRADE PATHWAY - The present invention relates to the use of compounds of general formula (I) and (II) for the preparation of a drug for preventing and/or treating disorders caused by Shiga toxins and related toxins. | 03-13-2014 |
20140073555 | USE OF MULTIVALENT SYNTHETIC LIGANDS OF SURFACE NUCLEOLIN FOR TREATING CANCER OR INFLAMMATION - A method for treating disorders involving deregulation of cell proliferation and/or angiogenesis comprising the administration of an effective amount of a multivalent synthetic compound comprising a support on which at least 3 pseudopeptide units are grafted, said compound being of formula (I). | 03-13-2014 |
20140072805 | MATERIALS AND PARTS THAT CAN WITHSTAND HIGH TEMPERATURES IN AN OXIDIZING MEDIUM, AND METHOD FOR MANUFACTURING SAME - A refractory material that can withstand high temperatures in an oxidizing medium and containing at least:
| 03-13-2014 |
20140070844 | VOLATILE/NON-VOLATILE MEMORY CELL - The invention concerns a memory device comprising at least one memory cell comprising: a first transistor ( | 03-13-2014 |
20140065658 | Method for Monitoring A Reaction, And Reaction System For Implementing Same - The invention relates to a method for monitoring a reaction and to a reaction system which are inexpensive, compact, easy to implement, and enable the reaction medium to be fully supervised throughout the entire experiment. For this purpose, the invention relates to a reaction system, in particular for microorganism cultures, including: at least one vessel (M | 03-06-2014 |
20140058061 | PROCESS FOR PREPARING PLATINUM-CARBENE COMPLEXES - Described is a process for preparing platinum-carbene complexes. | 02-27-2014 |
20140051148 | Cells and Methodology to Generate Non-Segmented Negative-Strand RNA Viruses - The present invention relates to recombinant cells as well as to methods for the generation of non-segmented negative-sense single-stranded RNA viruses (NNV or mononegavirales) from cloned deoxyribonucleic acid (cDNA), especially from measles virus and in particular from attenuated strains such as those approved for vaccination, in particular from the attenuated Schwarz measles virus and various recombinant Schwarz measles-based viruses expressing heterologous sequences. Such rescued viruses can be used, after amplification, as vaccines for immunization against measles and/or against the heterologous peptides or proteins expressed. | 02-20-2014 |
20140050940 | PART COMPRISING A COATING ON A SUPERALLOY METAL SUBSTRATE, THE COATING INCLUDING A METAL UNDERLAYER - The invention relates to a part comprising a coating on a superalloy metal substrate, the coating comprising a metal underlayer covering said substrate, the part being characterized in that said metal underlayer contains a base of nickel aluminide and also contains 0.5 at % to 0.95 at % of one or more stabilizer elements M from the group formed by Cu and Ag for stabilizing the gamma and gamma prime phases. | 02-20-2014 |
20140050716 | NOVEL PROCOAGULANT MOLECULAR DECOY FOR TREATING HEMOPHILIA A OR B WITH OR WITHOUT INHIBITOR - The present invention relates to a pharmaceutical composition including a modified factor Xa (GDXa), said modified GDXa being nonthrombogenic, able to bind to TFPI but not able to bind to phospholipids, for preventing or treating a hemorrhagic accident in a patient with hemophilia A or B with or without inhibitor. | 02-20-2014 |
20140050012 | PROGRAMMABLE VOLATILE/NON-VOLATILE MEMORY CELL - The invention concerns a memory device comprising at least one memory cell comprising: a first transistor ( | 02-20-2014 |
20140045262 | CONSTRUCTS AND METHOD FOR REGULATING GENE EXPRESSION OR FOR DETECTING AND CONTROLLING A DNA LOCUS IN EUKARYOTES - The present invention concerns constructs based on sequences derived from the partitioning system of plasmid and chromosomal DNA of bacteria, such as eukaryotic expression vectors, fusion proteins and polynucleotides encoding the same and also eukaryotic cells transformed with or expressing such constructs. The present invention also concerns the use thereof in the regulation of gene expression and/or in the detection and control of the dynamics, localization or metabolism of genomic DNA loci of interest in eukaryotic cells. | 02-13-2014 |
20140044362 | METHOD AND SYSTEM FOR ESTIMATING A SIMILARITY BETWEEN TWO BINARY IMAGES - The invention relates to a method and a system for estimating the resemblance between two images of optionally different modalities. More particularly, the invention makes it possible to characterize a similarity between two binary images formula (I): it allows in particular registration of images acquired in the fields of teledetection, medical imaging, industrial vision. | 02-13-2014 |
20140043062 | COMPACT VOLATILE/NON-VOLATILE MEMORY CELL - The invention concerns a memory device comprising at least one memory cell comprising: a first transistor ( | 02-13-2014 |
20140038883 | NOVEL AZACOUMARIN DERIVATIVES HAVING MDR PUMP INHIBITING ACTIVITY - The present invention relates to compounds of formula (I), where R | 02-06-2014 |
20140033333 | TRANSGENIC PIG FOR MUTANT GUCY2D AS CONE DYSTROPHY MODEL - The present invention relates to a transgenic pig as a model for studying a cone affecting disease, in particular a cone dystrophy or cone-rod-dystrophy, wherein the pig model expresses a dominant negative guanylate-cyclase-2D (GUCY2D) protein, in particular a GUCY2D protein comprising at least one mutation responsible for the appearance of a CORD6 cone dystrophy in a human being. The invention further relates to methods by which the transgenic pig is produced, to uses of said transgenic pig or of one of its elements to identify new biomarkers of a cone affecting disease and/or new compounds for preventing or treating such a disease. Novel methods for preventing or treating a cone affecting disease or for evaluating conditions needed to alleviate such a disease are further herein described. | 01-30-2014 |
20140027346 | SPHERICAL MATERIAL COMPRISING METALLIC NANOPARTICLES TRAPPED IN A MESOSTRUCTURED OXIDE MATRIX AND ITS USE AS A CATALYST IN REFINING PROCESSES - An inorganic material is described, constituted by at least two elementary spherical particles, each of said spherical particles comprising metallic nanoparticles having at least one band with a wave number in the range 750 to 1050 cm | 01-30-2014 |
20140026937 | Semiconductor Heterostructure and Photovoltaic Cell Including Such A Heterostructure - The invention relates to a heterostructure including a first region (R | 01-30-2014 |