MOR RESEARCH APPLICATIONS LTD Patent applications |
Patent application number | Title | Published |
20160114006 | COMPOSITIONS AND METHODS FOR TREATMENT OF RETINAL DEGENERATIVE DISEASES - This disclosure relates to compositions for use in treatment of a retinal degenerative disease, such as age related macular degeneration. The described compositions include agents for activating p38 and/or JNK signaling through the activation of TAK1 in the retinal pigment epithelium of a subject diagnosed with the disease. Methods of treatment of a retinal degenerative disease using the described compositions are also provided. | 04-28-2016 |
20160089423 | COMPOSITIONS AND METHODS FOR TREATING POST-OPERATIVE COMPLICATIONS OF CARDIOPULMONARY SURGERY - Disclosed herein are compositions and methods for treating damage inflicted by use of a cardio-pulmonary bypass (CPB) machine, particularly excessive bleeding and multi organ failure, by administering a pharmaceutical composition comprising alpha-1 antitrypsin (AAT). | 03-31-2016 |
20160029927 | METHOD AND SYSTEM FOR ANALYZING CRANIOFACIAL COMPLEX IMAGES - In a method of analysis, a target image is registered to define a plurality of keypoints arranged in sets corresponding to polygons or linear segments in the target image. A database of registered and annotated images is accessed and a polygon-wise comparison between the target image and each database image is employed. The comparison is used for projecting annotated locations from the database images into the target image. | 02-04-2016 |
20150299805 | NUCLEIC ACID DETECTION ASSAY - This invention is directed, inter alia, to methods and kits for rapid, easy and cost-effective methods of breast cancer prediction and diagnosis in inter alia, blood samples. | 10-22-2015 |
20150039088 | MIDDLE EAR PROSTHESIS - A middle ear prosthesis ( | 02-05-2015 |
20140350662 | DEVICE FOR PLACEMENT IN THE TRICUSPID ANNULUS | 11-27-2014 |
20140349874 | DIAGNOSTIC POLYMORPHISMS FOR CARDIAC DISEASE - One or more polymorphisms, including single nucleotide polymorphisms (SNPs), or combinations thereof, for diagnosis of cardiac disease, such as heart failure and atrial fibrillation. | 11-27-2014 |
20140303233 | ANTISENSE OLIGONUCLEOTIDES AGAINST cPLA2, COMPOSITIONS AND USES THEREOF - Antisense oligonucleotides against cPLA | 10-09-2014 |
20140216464 | FERTILITY PRESERVATION DEVICE - The invention relates to ovary apparatus for regulating the temperature of the ovary; and shielding it from radiation. The main function of the device is to preserve fertility of women treated with chemotherapy by lowering the ovary temperature while the toxic medications circulate in the patients' blood. The current invention utilizes shielding of the ovary to protect it from radiation, and temperature decrease to further limit the toxic effect of radiation. | 08-07-2014 |
20140199344 | ANTI-MEASLES CANCER IMMUNOTHERAPY - The present invention provides methods for treating specific populations of cancer patients by immunotherapy. The methods comprise administering an immunogenic composition eliciting an immune response to measles virus to patients having measles virus-immunoreactive cancer cells. | 07-17-2014 |
20140170644 | STERILE SAMPLE INJECTOR AND METHOD - A sterile injector comprises a body having a cavity, a hollow needle positionable at a distal end of the injector, a probe holder receivable within the needle, a probe connected to a distal end of the holder, and a driving element axially displaceable within the cavity, for causing relative motion between the probe and the needle upon displacement of the driving element. A sample is injected into a sealed container by displacing the driving element to a first position causing the probe to extend from the needle, applying the extended probe with a sample, displacing the driving element to a second position causing the sample laden probe to be retracted within the needle, piercing a seal of a sealed container with the needle, and displacing the driving element to a third position distally spaced from the first position, after which the probe is injected into the container interior. | 06-19-2014 |
20140148752 | A DEVICE FOR ADJUSTING THE INTRAOCULAR PRESSURE - Provided is a device for use in controlling the liquid outflow from the anterior chamber of the eye, methods of draining aqueous humor from the anterior chamber to the intra-orbital space using the device, methods for controlling the liquid outflow from the anterior chamber of the eye and further surgical methods for implanting the presently described device. | 05-29-2014 |
20140128946 | FERTILITY PRESERVATION DEVICE - The invention relates to ovary apparatus for regulating the temperature of the ovary, and shielding it from radiation. The main function of the device is to preserve fertility of women treated with chemotherapy by lowering the ovary temperature while the toxic medications circulate in the patients' blood. The current invention utilizes shielding of the ovary to protect it from radiation, and temperature decrease to further limit the toxic effect of radiation. | 05-08-2014 |
20140004488 | TRAINING, SKILL ASSESSMENT AND MONITORING USERS OF AN ULTRASOUND SYSTEM | 01-02-2014 |
20130345722 | TYMPANIC MEMBRANE REPAIR DEVICE - A method for repairing a perforation in a tympanic membrane comprising attaching a single patch to an undersurface of the tympanic membrane covering the perforation. | 12-26-2013 |
20130345132 | USE OF HGH FOR THE TREATMENT OF SMALL FOR GESTATIONAL AGE INFANTS UNDER TWO YEARS OF AGE - The invention provides a method and a composition for the treatment of infants age less than 2.5 years old defined as small for gestational age (SGA), including the use of hGH or any compound that increases blood levels of hGH or of IGF-I. Early use of the composition prevents the irreversible neurological and psychological damage of the children. | 12-26-2013 |
20130244972 | INJECTABLE CHITOSAN MIXTURES FORMING HYDROGELS - A chitosan composition which forms a hydrogel at near physiological pH and 37° C., comprising at least one type of chitosan having a degree of acetylation in the range of from about 30% to about 60%, and at least one type of chitosan having a degree of deacetylation of at least about 70% is disclosed. Further disclosed is a chitosan composition which forms a hydrogel at near physiological pH and 37° C., that includes at least one type of chitosan having a degree of deacetylation of at least about 70% and a molecular weight of from 10-4000 kDa, and at least one type of a chitosan having a molecular weight of from 200-20000 Da. Further disclosed are methods of preparation and uses of the chitosan compositions. | 09-19-2013 |
20130217996 | METHOD AND SYSTEM FOR ANALYZING IMAGES - A method of analysis is disclosed. The method comprises: registering a target image to define a plurality of keypoints arranged in sets corresponding to polygons or linear segments in the target image; accessing a database of registered and annotated images, and employing a polygon-wise comparison between the target image and each database image; and using the comparison for projecting annotated locations from the database images into the target image. | 08-22-2013 |
20130196335 | PROGNOSTIC METHODS, COMPOSITIONS AND KITS FOR PREDICTION OF ACUTE LYMPHOBLASTIC LEUKEMIA (ALL) RELAPSE - The present invention relates to prognostic methods and kits for the assessment and monitoring of relapse-free or disease-free survival of ALL patients. The detection is based on the use of detecting nucleic acids, specific for determination of the expression of at least one of miR-151-5p and miR-451 in a test sample. The invention thereby also provides methods and kits for monitoring and early diagnosis of cancerous disorders associated with low miR-151-5p and/or miR-451 expression, specifically ALL. | 08-01-2013 |
20130190275 | COMBINED THERAPIES OF ANTIPSYCHOTIC DRUGS AND TETRACYCLINES IN THE TREATMENT OF PSYCHIATRIC DISORDERS - The present invention provides combinations of an antipsychotic drug and a tetracycline, particularly minocycline, for the treatment of psychotic disorders, particularly schizophrenia. The invention also provides formulations wherein the release of one or both of the antipsychotic drug and the tetracycline is modified. The invention also provides methods using the combined therapy for treatment of psychotic disorders, particularly schizophrenia, comprising an antipsychotic drug and a tetracycline. | 07-25-2013 |
20130184601 | APPARATUS AND METHOD FOR DIAGNOSING OBSTRUCTIVE SLEEP APNEA - An embodiment of the invention provides a method of diagnosing obstructive sleep apnea, the method comprising: acquiring a sleep sound signal comprising sounds made by a person during sleep; detecting a plurality of snore sounds in the sleep sound signal; determining a set of mel-frequency cepstral coefficients for each of the snore sounds; determining a characterizing feature for the sleep sound signal responsive to a sum of the variances of the cepstral coefficients; and using the characterizing feature to diagnose obstructive sleep apnea in the person. | 07-18-2013 |
20130115645 | FGL-2 PROTHROMBINASE AS A DIAGNOSTIC TOOL FOR MALIGNANCY - The present: invention reveals a strong correlation between FGL-2 prothrombinase activity levels and the presence of a malignant proliferative disorder in a subject. Thus, the present invention provides FGL-2 prothrombinase activity as a diagnostic tool for malignancy. | 05-09-2013 |
20130018081 | AChE ANTISENSE OLIGONUCLEOTIDE AS AN ANTI-INFLAMMATORY AGENT - Disclosed is a novel use for AChE antisense oligonucleotides as anti-inflammatory agents, wherein said oligonucleotides are preferably as denoted by SEQ ID NO:1, SEQ ID NO:2 and SEQ ID NO:7. Methods of treatment of inflammatory conditions, as well as fever, and particularly inflammation-associated neuropathies such as Guillain-Barré Syndrome, are described. | 01-17-2013 |
20120277292 | ANTISENSE OLIGONUCLEOTIDES AGAINST cPLA2, COMPOSITIONS AND USES THEREOF - Antisense oligonucleotides against cPLA | 11-01-2012 |
20120246106 | MONITORING DEVICE FOR MANAGEMENT OF INSULIN DELIVERY - Monitoring system and method for use with diabetic treatment management. The system includes: a communication interface configured to permit access to stored raw log data, obtained over a certain time, being indicative of glucose measurements, meals consumed and insulin delivery; and a control unit including an unsupervised learning controller configured to receive and process said raw log data and determine at least one global insulin pump setting of basal rate, correction factor, carbohydrate ratio and insulin activity curve parameters. The system may include a processing unit including a first processor for processing measured data indicative of blood glucose level and generating first processed data, a second processor including at least one fuzzy logic module which receives input parameters corresponding to the measured data, the first processed data and a reference data, and processes the data to produce a qualitative output parameter to determine whether any treatment parameter should be modified. | 09-27-2012 |
20120155735 | SYSTEM AND METHOD FOR ANALYZING IMAGING DATA - A method of analyzing a stream of imaging data is disclosed. The method comprises: for each picture-element of the data, associating a vector of features indicative of temporal intensity variation relative to baseline intensity, thereby providing a plurality of vectors. The method further comprises clustering the picture-elements according to the vectors, thereby providing a plurality of clusters, and identifying different compartments in the vasculature based on the clusters. | 06-21-2012 |
20110257988 | MULTI-PHASE ANCHOR-BASED DIAGNOSTIC DECISION-SUPPORT METHOD AND SYSTEM - A medical diagnosis decision support system for assisting a health professional to diagnose a medical condition. The system is first provided with an anchor condition that can be a symptom, a sign, a laboratory test result, or an imaging test results or any combination thereof The system then guides users in a series of predetermined phases regarding abstract or concrete diagnosis groups that should be considered and appropriate data that should be collected during the clinical investigation process. The system suggests history and physical examination clinical data items, laboratory, and imaging tests that should be collected in order to differentiate among alternative diagnoses. In each phase, possible diagnoses are listed and ranked. | 10-20-2011 |
20110014231 | ANTI-MEASLES CANCER IMMUNOTHERAPY - The present invention provides methods for treating specific populations of cancer patients by immunotherapy. The methods comprise administering an immunogenic composition eliciting an immune response to measles virus to patients having measles virus-immunoreactive cancer cells. | 01-20-2011 |
20100204662 | CARDIAC VALVE LEAFLET AUGMENTATION - Methods and devices for augmenting an atrioventricular valve leaflet is disclosed. A method according to an exemplary embodiment includes piercing a leaflet of the valve to at least a portion of the leaflet's thickness to form a pierced section; and extending the leaflet using said pierced section. A device according to an exemplary embodiment of the invention includes a catheter comprising: a longitudinal tube having a lumen; and a cutting element extendable from the lumen. The cutting element is adapted for forming a limited cut in an atrioventricular valve. A device according to another exemplary embodiment of the invention includes a catheter comprising a longitudinal tube having a lumen; a cutting element extendable from the lumen and adapted for forming a cut in a leaflet of an atrioventricular valve; and a frame, configured to attach to the leaflet and stay attached to the leaflet when the heart beats. | 08-12-2010 |
20100152161 | COMPOSITIONS FOR WEIGHT MANAGEMENT - Methods and compositions for preventing or reducing weight gain associated with drug treatment, which utilize an H | 06-17-2010 |
20090304661 | Method And Composition For Proctecting Neuronal Tissue From Damage Induced By Elevated Glutamate Levels - A method of reducing extracellular brain glutamate levels is provided. The method comprising administering to a subject in need thereof an agent capable of modulating stress hormone activity thereby reducing blood glutamate levels, thereby reducing extracellular brain glutamate levels. | 12-10-2009 |
20090198324 | METHODS AND DEVICES FOR TREATMENT OF CARDIAC VALVES - Disclosed are methods for treatment of cardiac valve including augmenting a cardiac leaflet with the help of a ring associated with a membrane. Also disclosed are methods for treatment of cardiac valves including augmenting the tissue surrounding a cardiac valve, for example with the help of a tubular or annular implant, allowing relocation of the valve. In embodiments, the methods of the present invention improve leaflet coaptation, which in embodiments is useful for treating conditions such as ischemic mitral regurgitation. Also disclosed are devices useful for implementing the methods of the present invention. | 08-06-2009 |
20090192119 | Inhibition of the Renin-Angiotensin System for the Treatment of Renal, Vascular and Cartilage Pathology - A method of treating a disease or condition in which up-regulating GAGs is therapeutically beneficial is disclosed. The method comprises locally administering to a subject a therapeutically effective amount of an agent capable of down-regulating activity or expression of a component of the renin-angiotensin system. | 07-30-2009 |
20090186043 | Method and compositions for preventing and treating streptococcus pneumoniae infection - A method of preventing and/or treating | 07-23-2009 |
20090105812 | DEVICE AND METHOD FOR USE IN AORTIC VALVE DISEASE TREATMENT - A device is presented for assisting an insufficient aortic valve. The device is configured as an auxiliary valve and comprises a resilient deformable sleeve-like valve, deformation of the sleeve-like valve shifting the valve between its closed and opened positions. | 04-23-2009 |
20090035354 | Device and Method for Treating the Anal Sphincter - A rectally insertable device for localized drug delivery to the anal sphincter of a subject, a method of using the device and the use of the device is disclosed. The device comprises a shell for containing an active pharmaceutical ingredient, the shell being substantially impermeable to the active pharmaceutical ingredient wherein a lower portion of the shell is configured to release the active pharmaceutical ingredient from the shell and wherein when the device is inserted into the rectum of the subject, the lower portion of the shell is proximal to the anal sphincter, such that the active pharmaceutical ingredient is released proximal to the anal sphincter. | 02-05-2009 |
20090010947 | Red Microalgae Expressing Exogenous Polypeptides And Methods Of Generating And Utilizing Same - A method of transforming red microalgae is provided. The method is effected by: (i) culturing red microalgae cells under predetermined light/dilution conditions to thereby generate competent red microalgae cells; and (ii) introducing at least one exogenous polynucleotide into said competent red microalgae cells, thereby transforming the red microalgae. | 01-08-2009 |
20090005331 | AChE antisense oligonucleotide as an anti-inflammatory agent - Disclosed is a novel use for AChE antisense oligonucleotides as anti-inflammatory agents, wherein said oligonucleotides are preferably as denoted by SEQ ID NO:1, SEQ ID NO:2 and SEQ ID NO:7. Methods of treatment of inflammatory conditions, as well as fever, and particularly inflammation-associated neuropathies such as Guillain-Barré Syndrome, are described. | 01-01-2009 |
20090004276 | Novel injectable chitosan mixtures forming hydrogels - A chitosan composition which forms a hydrogel at near physiological pH and 37° C., comprising at least one type of chitosan having a degree of acetylation in the range of from about 30% to about 60%, and at least one type of chitosan having a degree of deacetylation of at least about 70% is disclosed. Further disclosed is a chitosan composition which forms a hydrogel at near physiological pH and 37° C., comprising at least one type of chitosan having a degree of deacetylation of at least about 70% and a molecular weight of from 10-4000 kDa, and at least one type of a chitosan having a molecular weight of from 200-20000 Da. Further disclosed are methods of preparation and uses of the chitosan compositions. | 01-01-2009 |
20080287380 | Antisense Oligonucleotides Against Cpla2, Compositions and Uses Thereof - Antisense oligonucleotides against cPLA | 11-20-2008 |
20080233149 | Use of Erythropoietin for Enhancing Immune Responses and for Treatment of Lymphoproliferative Disorders - The present invention relates to the use of erythropoietin (EPO) for enhancing immune responses and for the treatment of lymphoproliferative disorders, excluding multiple myeloma. Accordingly to the invention EPO may be administered with a viral or bacterial vaccine. | 09-25-2008 |