20120226445 | Method for Improving a Chromatographic Detection Limit for an Analyte - A method for improving the chromatographic detection limit for an analyte including a) producing a chromatogram with a peak of the analyte, b) calculating a regression straight line for a baseline from measured values of a section without a peak in the chromatogram, c) calculating a regression function from measured values of the peak of the analyte, d) subtracting the regression function from the chromatogram, e) calculating a regression polynomial for the baseline from the values of the chromatogram which have been changed in step d), calculating a further regression function from the measured values of the peak in the produced chromatogram, g) calculating a peak area between the regression polynomial and the further regression function, h) repetition of step d) with the further regression function instead of the regression function and of steps e), f) and g), until the calculated peak area changes by less than a predetermined amount. | 09-06-2012 |