UNIVERSITY COLLEGE CORK, NATIONAL UNIVERSITY OF IRELAND, CORK Patent applications |
Patent application number | Title | Published |
20160095329 | EDIBLE SNACK FOOD PRODUCT HAVING A LOW WATER CONTENT AND A HIGH SOLIDS CONTENT, AND A METHOD FOR THE PRODUCTION THEREOF - A process for making an edible snack food product having a low water content and a high solids content is described. The process comprises a step of providing an edible porous body, for example a freeze-dried fruit or vegetable slice or an extruded cereal product, and coating the body in a high-solids polymer solution, for example 25% (w/w) whey protein isolate, such that the polymer solution infuses into the pores at or close to the surface of the body but does not rehydrate the porous body. Coating may be achieved by spraying the product with the polymer solution or by briefly immersing the porous body in the solution. The coated porous body is then heated to a high temperature to dehydrate the infused polymer solution. This results in closure of the pores at or close to the surface of the porous body. | 04-07-2016 |
20160043074 | JUNCTIONLESS NANOWIRE TRANSISTORS FOR 3D MONOLITHIC INTEGRATION OF CMOS INVERTERS - The invention provides a three dimensional (3D) semi-conductor device comprising a first junctionless transistor doped with dopants of the same polarity; a second junctionless transistor doped with dopants of the same polarity; and the second junctionless transistor and the first junctionless transistor comprise an opposite dopant polarity are stacked in a vertical arrangement, where the first and second junctionless transistors are separated by an insulating layer. The invention makes use of the fact that the transistors are uniformly doped with the same polarity to provide a junctionless transistor. The junctionless concept provides that the junction is already formed, so there is no high temperature step associated with junction formation or junction regrowth. This is an important advantage in the junctionless concept in relation to 3D monolithic integration that allows for vertical stacking of the transistors to form a three dimensional CMOS inverter. | 02-11-2016 |
20150328449 | A THORACOSCOPIC ELECTROPORATION DEVICE WITH A SUCTION HEAD AND WITH NEEDLE ELECTRODES - A thoracoscopic electroporation device for carrying out electroporation on tissue includes a suction head and a plurality of needle electrodes. The needle electrodes include a central needle providing a first electrode and a plurality of second needles which are spaced-apart around the periphery of the suction head. The electrodes are movable from a retracted configuration to a deployed configuration and in the deployed configuration the needles extend from the suction head. The suction head has a retracted delivery configuration and an expanded deployed configuration. The suction head includes a suitable flexible material for biasing the suction head into the expanded deployed configuration. The suction head has channels for the needles and the needles are movable through the channels from the retracted to the deployed configuration. In the deployed configuration, the central first needle extends beyond the peripheral needles. | 11-19-2015 |
20150303345 | AMPLIFIED DETECTOR FORMED BY LOW TEMPERATURE DIRECT WAFER BONDING - In one embodiment the invention relates to a photodetector device sensitive for wavelengths comprising a doped Ge absorbing material bonded to a substrate material locally of opposite doping polarity and an interface layer formed between the Ge absorbing material and the substrate material to form a p-n junction. In one embodiment the bonded material comprises a p-doped Ge wafer and n-doped Si or So I wafer and obtained from a low-temperature heat treatment after bonding. The invention also discloses a process for making a photodetector. | 10-22-2015 |
20140296172 | Method for screening compounds comprising the use of picornavirus protease 2A - A method of screening compounds or molecules comprising the steps of: translating a sequence encoding the amino acid sequence comprising SEQ ID No. 29 in a translation system in the presence of a test compound or molecule; and analysing the translation product(s) for the presence of one or more of (a) a peptide comprising the amino acids Pro-Gly at the C terminus and a peptide comprising the amino acid Pro at the N terminus: or (b) a peptide comprising the amino acid sequence of SEQ ID No. 29. | 10-02-2014 |
20140286904 | ANITMICROBIAL PEPTIDE PRODUCED BY INTESTINAL LACTOBACILLUS SALIVARIUS - An antimicrobial peptide having potent antibacterial activity against | 09-25-2014 |
20140120182 | METHOD FOR THE TREATMENT OF CANCER - The invention is based on the surprising finding that treatment with a chemotherapeutic agent such as 5-fluorouracil (5-FU) and an autophagy inducer effectively inhibit the continued growth of, and prevent the recovery following drug withdrawal, of cancer cells. In vivo, drug resistance from a failure to adequately engage in apoptotic programmed cell death leads to a recurrence of cancer and tumours can remain dormant for periods of time before re-emerging as drug resistant metastases. It has been hypothesised that autophagy (Type II cell death) may help cancer cells survive in response to growth limiting conditions, such as nutrient depletion, hypoxia, absence of growth factor, or presence of cytotoxic drug. LiCl is a known autophagy inducer and accelerates cell survival to autophagic programmed cell death. | 05-01-2014 |
20130295679 | PREDICTION OF A SMALL-FOR-GESTATIONAL AGE (SGA) INFANT - A method of predicting a SGA infant in a patient at a pre-symptomatic gestational stage is described. The method comprises a step of assaying a biological sample from the patient for an abundance of a plurality of metabolite biomarkers selected from the 19 metabolite biomarkers of Table IV, correlating the abundance of the plurality of metabolite biomarkers with a metabolite fingerprint of SGA shown in Table IV, and predicting SGA based on the level of correlation between the abundance of the plurality of metabolite biomarkers and the metabolite fingerprint of Table IV. | 11-07-2013 |
20130275049 | System and Method of Assessing Allergic Status in a Subject - A method of assessing the allergic status of a subject to a specific allergen, comprises the steps of determining a subject-specific numeric value for a plurality of variables comprising age, sex, SPT, IgE, (sIgE or tIgE minus sIgE) and allergic symptoms, applying an allergen-specific weighting to the numeric value for each variable, and correlating the weighted numeric values with allergic status for the subject. The weighted numeric values is correlated with allergenicity status using a deterministic probability function. | 10-17-2013 |
20130245606 | HYDROGEL BASED OCCLUSION SYSTEMS - A hydrogel based occlusion system, a method for occluding vessels, appendages or aneurysms, and a method for hydrogel synthesis are disclosed. The hydrogel based occlusion system includes a hydrogel having a shrunken and a swollen state and a delivery tool configured to deliver the hydrogel to a target occlusion location. The hydrogel is configured to permanently occlude the target occlusion location in the swollen state. The hydrogel may be an electro-activated hydrogel (EAH) which could be electro-activated with a delivery system to control the degree of swelling/shrinking. | 09-19-2013 |
20130209429 | Modulation of Tissue Fatty Acid Composition of a Host by Human Gut Bacteria - The current invention provides use of a CLA-producing bacterium for the in vivo conversion in the gut of polyunsaturated fatty acids to CLA. The CLA-producing bacterium is selected from one or more of the group consisting of propionibacteria, lactobacilli, lactococci and streptococci, and bifidobacteria. | 08-15-2013 |
20130154690 | NESTED DIGITAL DELTA-SIGMA MODULATOR - Methods and systems are disclosed that provide a radio frequency synthesizer that generates precise frequencies over a large radio frequency range. The radio frequency synthesizer can provide a high resolution of frequency generation and still provide precise frequencies over a range of radio frequencies. The precision and resolution while maintaining a large operating range come from the ability of the frequency synthesizer to generate frequencies as a product of a plurality of moduli. For example, the frequency can be generated from a reference frequency using a first modulus and a second modulus. The plurality of modulo can be implemented using nested digital delta-sigma modulators in a fractional-N frequency synthesizer. | 06-20-2013 |
20130121977 | LACTOBACILLUS PLANTARUM SPECIES POSSESSING BROAD SPECTRUM ANTI-FUNGAL ACTIVITY AND EXHIBITING HIGH HEAT TOLERANCE AND OSMOTOLERANCE - Isolated strains of | 05-16-2013 |
20130073212 | DETECTION OF RISK OF PRE-ECLAMPSIA - A method for the early prediction of risk of hypertensive disorders in pregnant women, including for example eclampsia, mild pre-eclampsia, chronic hypertension, EPH gestosis, gestational hypertension, superimposed pre-eclampsia, HELLP syndrome, or nephropathy. | 03-21-2013 |
20120305893 | TRANSISTOR DEVICE - The invention provides transistor device comprising a source, a drain and a connecting channel, the channel is a nano-structure device adapted to allow current flow between the source and drain. The channel comprises an ultra-high doping concentration and is of the same polarity as in the source and/or drain. Essentially the transistor device of the present invention acts as a junctionless, highly-doped gated resistor. In the context of optimal performance of the transistor high doping means equal to or exceeds 1×10 | 12-06-2012 |
20120289681 | CONJUGATES OF CELL-PENETRATING PEPTIDES AND PHOSPHORESCENT METALLOPORPHYRINS FOR INTRACELLULAR OXYGEN MEASUREMENT - A phosphorescent compound of general Formula I, | 11-15-2012 |
20120189550 | ORALLY ADMINISTERED BACTERIA AS VEHICLES FOR SYSTEMATIC DELIVERY OF AGENTS - The current invention relates to the use of a bacterial species in the preparation of a composition adapted for oral administration for the delivery of an agent to a site in the body. The site in the body may be an organ or a tumour site. The bacterial species is a food grade, non-pathogenic, gram-positive bacteria capable of anaerobic growth. | 07-26-2012 |
20120177608 | PSEUDOMONAS AERUGINOSA BACTERIOPHAGE(S) AND USES THEREOF - An isolated bacteriophage MR299-2 or NH-4 deposited under NCIMB Deposit Accession Nos. 41729 and 41730, respectively, is described. The phages have lytic activity against | 07-12-2012 |
20120171325 | METHOD FOR THE PRODUCTION OF A GUM BASE - A method for the preparation of a gum base or chewable entity comprises the step of treating a mixture comprising cereal protein, for example gluten, and water, optionally in combination with sugar, sugar substitute or other functional ingredient, at a hydrostatic pressure of at least 100 MPa for at least 2 mins. Generally, the mixture is pressure treated at an elevated pressure of at least 25° C. The temperature, pressure and treatment time may be varied provided that the combination of the three results in the modification of the viscoelastic properties of the mixture to resemble that of conventional chewing gum. The treatment time of the current invention is inversely related to the hydrostatic pressure and temperature of the treatment. Thus, if the pressure and/or the temperature are increased, the treatment time may be reduced. | 07-05-2012 |
20120155881 | ELECTRONIC DISPERSION COMPENSATION SYSTEM AND METHOD - The invention provides a system and method, for an optical communication network to compensate impairments in the network, using electronic dispersion compensation, said system comprising optical means comprising two or more optical-to-electrical converters for generating at least two electrical signals, comprising amplitude and instantaneous frequency of a received distorted optical signal, and an electrical circuit adapted to perform a full-field reconstruction of the received distorted optical signal using said electrical signals. The system is characterised by a dispersive transmission line circuit with compensation parameters updated at a selected rate to process said full-field reconstructed signal and compensate for coarse chromatic dispersion; and an adaptive electronic equalization circuit with compensation parameters updated at a rate faster than those in the said dispersive transmission line circuit to provide a fine impairment compensation of said reconstructed signals. The system and method of the invention achieves low-cost long-distance transmission, up to 2000 km, while maintaining the fast-adaptive compensation capability and provide a method for transparent long-haul and metro-optical networks. | 06-21-2012 |
20120114003 | LASER DEVICE, A LIGHT SIGNAL GENERATION DEVICE, AND AN OPTICAL RESONATOR AND A METHOD FOR PRODUCING LIGHT - A laser device includes a ridge waveguide having an active layer between upper and lower cladding layers. A ridge formed in the upper cladding layer defines the width of a light guiding region in the active layer, and is formed so that a portion of the light guiding region extends into the ridge. A plurality of reflecting slots extend across and into the ridge to a depth sufficient to extend into the extending portion in order that the reflectivity of each slot is on the order of 2%. The slots intersect more than 20% of the total mode energy in the light guiding region, and this in combination with the gain of the active layer facilitates lasing within the light guiding region independently of the reflectivity of end facets of the waveguide. The laser device is particularly suitable for integrally forming with other optical components on a single semiconductor chip. | 05-10-2012 |
20110269671 | NISIN DERIVATIVES AND THE USE THEREOF - The present invention relates to a nisin derivative comprising amino acid substitutions in the peptide sequence encoding the hinge region of the protein, wherein the derivative exhibits an increased anti-microbial activity. | 11-03-2011 |
20110236986 | SENSOR MATERIAL AND USES THEREOF TO SIMULTANEOUSLY SENSE TWO ANALYTES - A sensor material of the type comprising a long-decay photoluminescent, protonable dye embedded in a suitable polymeric matrix, is used for generating a specific optical response to two different analytes present in a sample, thus allowing selective determination of the two analytes in the sample. Also described is a method for the simultaneous sensing of a first and second analyte in a sample. The method comprises the steps of irradiating a sensor material of the type comprising a long-decay photoluminescent protonable dye embedded in a suitable polymeric matrix with light of one or two wavelengths, determining photoluminescence intensity and lifetime signals originating from the sensor, and correlating the photoluminescence intensity signal with a concentration of the first analyte and the photoluminescence lifetime signal(s) with the concentration of the second analyte. | 09-29-2011 |
20110200569 | INCREASING THE SHELF LIFE OF BAKERY AND PATISSERIE PRODUCTS BY USING THE ANTIFUNGAL LACTOBACILLUS AMYLOVORUS DSM 19280 - The current inventions relates to a strain of | 08-18-2011 |
20110136898 | TREATMENT OF RETINAL DEGENERATION - The use of a compound of general formula (I): or a pharmaceutically acceptable salt thereof, in the manufacture of a medicament for the treatment or prevention of a disease or condition characterised by apoptosis or degeneration of mammalian cells, wherein: R1 is a alkoxy, alkyl, ether or ester group; R2 is H or has the formula wherein Y is linear or branched, saturated or unsaturated, aliphatic group with from 2 to 23 carbon atoms, or a cyclic group, and which can contain substituents selected from the group consisting of hydroxyl, alkoxy, amino, carboxyl, cyano, nitro, alkylsuphonyl or halogen atoms, X is O or S; and R3 is any substituent. | 06-09-2011 |
20110136163 | Method of Toxicological Assessment - A method of assessing toxicity of a candidate agent to a sample of cells comprises the steps of providing a sample of cells, exposing the cells to the candidate agent for a suitable period of time, assaying the cells to measure data for at least one parameter of cellular function; and correlating the measured data of the at least one parameter of cellular function with toxicity, wherein the step of exposing the cells to the candidate agent is carried out in the presence of a reagent capable of facilitating transport of the candidate agent into the cell. The transport reagent may be an endocytosis, pinocytosis inducing agent, a peptide, or a liposome. The at least one parameter of cellular function may be selected from the group consisting of: cell viability; proliferation rate; membrane integrity; and a metabolic parameter. Also described is a method of generating a toxicity signature for a candidate agent comprising the step of carrying out the method of the invention for a plurality of cellular function parameters, and compiling the measured data for each of the cellular function parameters to provide a toxicity signature. | 06-09-2011 |
20110110853 | PRIMITIVE VASCULAR PROGENITOR CELLS AND USES THEREOF - Described herein are isolated mammalian cells (progenitor cell biomarkers), referred to as primitive vascular progenitor cells (PVPC), which are present in and isolated from blood (e.g., peripheral blood) and useful as biomarkers of vascular remodeling in mammals (e.g., humans, rodents). | 05-12-2011 |
20110019823 | OPTICAL COMMUNICATION SYSTEM AND METHOD FOR SECURE DATA COMMUNICATION USING QUANTUM KEY DISTRIBUTION - The invention provides time-synchronised transmission of data on the (polarisation or phase-modulated) QKD channel and the (on-off modulated) conventional channel such that a QKD bit is only transmitted when a zero, or sequence of zeros, is transmitted on the conventional channel. Also, there is co-directional propagation of the QKD and conventional channel. Further, there is dispersion management through wavelength selection or control of fibre properties or other means such that the “walk-off in time of the QKD pulses and the Raman pulses generated by the ones on the conventional channel is less than or of the order of one bit period. The latter can be achieved, for example, by placing the conventional and QKD channel wavelengths close to the point where the group velocity-induced time delay for optical pulses propagating in the fibre reaches a minimum. This dispersion minimum occurs at a wavelength of 1.3 microns in standard fibre. The invention discloses a receiver embodiment to implement the invention. | 01-27-2011 |
20110014303 | METHOD FOR THE TREATMENT OF CANCER - The invention is based on the surprising finding that treatment with a chemotherapeutic agent such as 5-fluorouracil (5-FU) and an autophagy inducer effectively inhibit the continued growth of, and prevent the recovery following drug withdrawal, of cancer cells. In vivo, drug resistance from a failure to adequately engage in apoptotic programmed cell death leads to a recurrence of cancer and tumours can remain dormant for periods of time before re-emerging as drug resistant metastases. It has been hypothesised that autophagy (Type II cell death) may help cancer cells survive in response to growth limiting conditions, such as nutrient depletion, hypoxia, absence of growth factor, or presence of cytotoxic drug. LiCl is a known autophagy inducer and accelerates cell survival to autophagic programmed cell death. | 01-20-2011 |
20100302933 | Robust Routing of Data in Wireless Networks - A wireless network ( | 12-02-2010 |
20100290495 | LASER DEVICE, A LIGHT SIGNAL GENERATING DEVICE, AND AN OPTICAL RESONATOR AND A METHOD FOR PRODUCING LIGHT - A laser device ( | 11-18-2010 |
20100284979 | Modulation of Tissue Fatty Acid Composition of a Host by Human Gut Bacteria - The current invention provides use of a CLA-producing bacterium for the in vivo conversion in the gut of polyunsaturated fatty acids to CLA. The CLA-producing bacterium is selected from one or more of the group consisting of propionibacteria, lactobacilli, lactococci and streptococci, and bifidobacteria. | 11-11-2010 |
20080311080 | BIFIDOBACTERIUM IN THE TREATMENT OF INFLAMMATORY DISEASE - A strain of | 12-18-2008 |