ADELAIDE RESEARCH & INNOVATION PTY LTD Patent applications |
Patent application number | Title | Published |
20150291698 | Methods and Products for Preventing and/or Treating Metastatic Cancer - The present disclosure relates to the prevention and/or treatment of metastatic cancer. Certain example embodiments of the present disclosure provide a method for preventing and/or treating a metastatic cancer in a subject. The method comprises administering to the subject a therapeutically effective amount of an inhibitor of a chemokine receptor CCX-CKR. | 10-15-2015 |
20150216966 | CELLULAR VACCINE AND METHOD OF INDUCING AN IMMUNE RESPONSE IN A SUBJECT - The present invention relates to methods of inducing or enhancing an immune response against an immunogen in a subject. The invention further includes isolated nucleic acid vaccines, cellular vaccines, fusion proteins, expression vectors, vaccines, and immunogenic compositions for use therein. | 08-06-2015 |
20150203599 | POLYSACCHARIDE SYNTHASES (X) - The present disclosure relates generally to polysaccharide synthases. The present disclosure reveals that a subset of the CesA gene family encode XynS xylan synthases. As a result of the identification of XynS nucleic acids, and corresponding amino acid sequences that encode XynS xylan synthases, the present invention provides, inter alia, methods and compositions for modulating the level and/or activity of xylan synthase in a cell and/or modulating the level of xylan produced by a cell. | 07-23-2015 |
20150054284 | HYBRID RECEIVER-COMBUSTOR - A hybrid receiver-combustor ( | 02-26-2015 |
20150010914 | BIOMARKERS FOR GASTRIC CANCER AND USES THEREOF - The present invention provides biological markers associated with gastric cancer. In particular, the present invention provides a method of diagnosing gastric cancer (GC) in a subject, the method including: measuring an expression level of one or more proteins in the subject, wherein the one or more proteins are selected from the group consisting of vitamin D binding protein (VDBP), clusterin, insulin like growth factor binding protein complex acid labile subunit (IGFALS), and afamin; comparing the expression level of the or each protein in the subject to a reference expression level for the or each protein; and diagnosing GC in the subject on the basis of the comparison. On the basis of the identification of biological markers associated with gastric cancer, the present invention also provides a method of determining if a subject is susceptible to developing gastric cancer, a method of assessing progression of gastric cancer in a subject, a method for screening a candidate therapeutic agent useful for treating gastric cancer in a subject, and a kit for diagnosing gastric cancer in a subject. | 01-08-2015 |
20140330131 | METHOD OF AND A SYSTEM FOR CHARACTERISING A MATERIAL - A system for characterising a material is provided. The system includes an optical sensor including an optical waveguide, the optical waveguide having first and second ends and being characterised by having a numerical aperture greater than or equal to 0.2, and a microresonator including an optically active material, the microresonator being positioned in an optical near field of an end face of the first end of the optical waveguide such that the optically active material is excitable by light. The system further includes a light source for exciting the optically active material of the microresonator so as to generate whispering gallery modes (WGMs) in the microresonator and a light collector for collecting an intensity of light that is associated with the WGMs excited in the microresonator. | 11-06-2014 |
20140073052 | MODULATION OF GRANULOSA CELL APOPTOSIS - The present invention relates to a method of modulating apoptosis of a granulosa cell. The method includes one or more of the following steps: (i) modulating the concentration and/or activity of BMP-15 and/or BMP-6 that the granulosa cell is exposed to; (ii) modulating activity of a BMP-15 dependent signalling pathway in the granulosa cell; and (iii) modulating activity of a BMP-6 dependent signalling pathway in a granulosa cell. | 03-13-2014 |
20140065241 | USES OF (-)-PERHEXILINE - A method for treating or preventing a disease, condition or state in a subject in need thereof by administering to the subject an effective amount of the (−)-enantiomer of perhexyline or a pharmaceutically acceptable salt, prodrug or derivative thereof, substantially free of the (+)-enantiomer, or pharmaceutical composition containing same. The disease, condition or state may be associated with altered tissue energetics, impaired tissue energetics, altered cardiac tissue energetics, impaired cardiac tissue energetics, altered hepatic tissue energetics, impaired hepatic tissue energetics, and diabetes. | 03-06-2014 |
20130242109 | Network Surveillance System - A method for estimating the activity topology of a set of sensed data windows is described. Each of the sensed data windows related to a corresponding sensed region. The method includes the steps of determining a subset of sensed data windows that are not connected; and excluding the subset of sensed data windows from the set of sensed data windows. In one embodiment, the sensed data windows corresponding to image windows such as would be provided by a visual surveillance system. | 09-19-2013 |
20130178495 | IBUDILAST FOR RELIEVING NEGATIVE EFFECTS OF MEDICATION OVERUSE HEADACHE - Certain negative effects of medication overuse headache (MOH) are relieved by administering ibudilast or a pharmaceutically acceptable salt thereof. | 07-11-2013 |
20130063726 | SENSOR AND A METHOD FOR CHARACTERISING A DIELECTRIC MATERIAL - The present disclosure provides a method of characterising a dielectric material. The method comprises the step of providing a light source, a light collector and a sensor. The sensor is arranged so that an evanescent field of light penetrates through a surface of the sensor and surface plasmons are generated at the surface of the sensor when suitable light is directed along at least a portion of the sensor. The method also includes the step of exposing the surface of the sensor to the dielectric material so that an interface is formed between the surface and the dielectric material. Further, the method comprises guiding light along at least a portion of the sensor to generate the surface plasmons. In addition, the method comprises the step of collecting an intensity of light from the interface as a function of a spectral parameter of the light. Further, the present disclosure provides an apparatus for characterising the dielectric material in accordance with the method. | 03-14-2013 |
20120260370 | Plant Egg Cell Transcriptional Control Sequences - The present invention relates generally to transcriptional control sequences. Generally, the present invention relates to transcriptional control sequences that specifically or preferentially direct expression of a nucleotide sequence of interest in a plant egg cell. The present invention is predicated, in part, on the identification of transcriptional control sequences derived from EC1 genes which, in preferred embodiments, direct preferential expression in an egg cell of at least one plant taxon. | 10-11-2012 |
20120132830 | OPTICAL DETECTOR FOR DETECTING RADIATION - The present disclosure provides an optical detector for detecting radiation. The optical detector includes an optical light guide that incorporates a sensing region. The sensing region includes a sensing material that emits luminescence light when the sensing material is exposed to suitable ionizing radiation and accrues trapped charge which is released and produces optically stimulated luminescence (OSL) when the sensing material is optically stimulated. The optical detector also includes a light source for optically stimulating the sensing material and a light detector for detecting the OSL. The optical light guide is arranged to guide light through the sensing region and between the sensing region and the luminescence light detector. | 05-31-2012 |
20120041694 | METHOD AND SYSTEM FOR ASSESSMENT OF PIPELINE CONDITION - A method and system for assessing the condition of a pipe carrying a fluid is disclosed. The method includes the steps of generating a pressure wave in the fluid being carried along the pipe and detecting a pressure wave interaction signal resulting from an interaction of the pressure wave with a localised variation in pipe condition. The method then involves determining from the timing of the pressure wave interaction signal the location of the localised variation in pipe condition and the extent of the localised variation in pipe condition based on a characteristic of the pressure wave interaction signal. | 02-16-2012 |
20110045298 | FABRICATION OF NANOWIRES - A method of forming a nanowire is disclosed. In one embodiment, a primary preform is formed comprising at least one central region and a support structure. The primary preform is then drawn to a cane, which is then inserted into an outer portion, to form a secondary preform. The secondary preform is then drawn until the at least one central portion is a nanowire. The method can produce nanowires of far greater length than existing methods, and can reduce the likelihood of damaging the nanowire when handling. | 02-24-2011 |
20100305183 | METHOD AND COMPOSITION FOR REDUCING REPERFUSION INJURY - The present invention relates to a method of preventing and/or reducing reperfusion injury to a tissue, organ, or organ system in a subject. The method includes administering to the subject an effective amount of a substance P receptor antagonist. | 12-02-2010 |
20100237255 | OPTICAL FIBER SENSOR - A sensor based on optical fiber technology is described. The sensor includes an elongate core for propagating light having an excitation wavelength; an interaction region that includes a fluorescent material for excitation by the propagated light to produce fluorescent light; and an interface region defining a boundary between the elongate core and the interaction region. The elongate core of the sensor is adapted to increase an intensity of the propagated light at the interface region to increase the amount of captured fluorescent light in the elongate core. | 09-23-2010 |
20100203064 | METHODS AND COMPOSITIONS FOR MODULATING WOUND REPAIR - The present invention relates to a method of modulating repair of a wound. The method includes modulating expression and/or activity of Flightless I in cells involved in repair of the wound. | 08-12-2010 |
20100067801 | Network Surveillance System - A method for estimating the activity topology of a set of sensed data windows is described. Each of the sensed data windows related to a corresponding sensed region. The method includes the steps of determining a subset of sensed data windows that are not connected; and excluding the subset of sensed data windows from the set of sensed data windows. In one embodiment, the sensed data windows corresponding to image windows such as would be provided by a visual surveillance system. | 03-18-2010 |
20100017899 | METHOD FOR THE ISOLATION OF PLURIPOTENT CELLS FROM A PRE-IMPLANTATION EMBRYO IN A CULTURE MEDIUM FREE FROM ANIMAL SERUM - The present invention provides a method of isolating a pluripotent cell from a pre-implantation embryo without isolation of the pluripotent cells from other cells, the method including propagating a whole pre-implantation embryo including one or more pluripotent cells, embedded in a feeder cell layer and cultivated in a medium substantially free of serum, and isolating a pluripotent cell from the one or more pluripotent cells. The present invention also provides pluripotent cells generated by the method and uses thereof. | 01-21-2010 |
20090220785 | METHOD AND DEVICE FOR FORMING MICROSTRUCTURED FIBRE - A die and method for extruding an extrudable material to form an extruded member is described. In one embodiment, the die comprises a barrier member comprising a plurality of feed channels that extend through the barrier member. Furthermore, the die incorporates a passage forming member extending from the barrier member substantially in the direction of extrusion. The feed channels are arranged with respect to the passage forming member to allow the extrudable material to substantially flow about the passage forming member to form a corresponding passage in the extruded member. | 09-03-2009 |
20090205074 | TRANSCRIPTION REGULATORS FOR REPRODUCTION ASSOCIATED PLANT PART TISSUE SPECIFIC EXPRESSION - The present invention relates generally to transcriptional control sequences for effecting expression of a nucleotide sequence of interest in a plant. The present invention is predicated, in part, on the identification and functional characterisation of transcriptional control sequences derived from genes which encode polypeptides comprising the amino acid sequence set forth in SEQ ID NO: 1 and homologs thereof. Among other things, the present invention has identified that transcriptional control sequences derived from the subject genes can effect specific or preferential expression of an operably connected nucleotide sequence in a reproduction-associated plant part such as a seed or anther. | 08-13-2009 |
20090191635 | PLANT EGG CELL TRANSCRIPTIONAL CONTROL SEQUENCES - The present invention relates generally to transcriptional control sequences. Generally, the present invention relates to transcriptional control sequences that specifically or preferentially direct expression of a nucleotide sequence of interest in a plant egg cell. The present invention is predicated, in part, on the identification of transcriptional control sequences derived from EC1 genes which, in preferred embodiments, direct preferential expression in an egg cell of at least one plant taxon. | 07-30-2009 |
20090158457 | SPECIFIC EXPRESSION USING TRANSCRIPTIONAL CONTROL SEQUENCES IN PLANTS - The present invention relates generally to methods and transcriptional control sequences suitable for effecting expression of a nucleotide sequence of interest in a plant. More particularly, the present invention relates to methods and transcriptional control sequences suitable for directing specific or preferential expression of a nucleotide sequence of interest in a plant seed. Of particular interest as a transcriptional control sequence in this invention is the promoter PR602 (SEQ ID NO: 1) found in the 5′-untranslated region of the rice END1-like gene and isolated from a rice panicle library. | 06-18-2009 |
20090118372 | Inhibitors Of Biotin Protein Ligase - The present invention relates to a method for identifying an inhibitor of a biotin protein ligase. The method include the steps of (a) providing a substrate, wherein the substrate may be biotinylated; (b) contacting the substrate with biotin and a biotin protein ligase in the presence of a test compound; (c) determining the extent of biotinylation of the substrate by the biotin protein ligase in the presence of the test compound; and (d) identifying the test compound as an inhibitor of the biotin protein ligase by a reduction in the biotinylation of the substrate in the presence of the test compound as compared to the extent of biotinylation of the substrate in the absence of the test compound. | 05-07-2009 |
20090009513 | METHOD AND SYSTEM FOR GENERATING A 3D MODEL - A method for generating a three dimensional (3D) model of an object is depicted in a two dimensional (2D) image is disclosed, The 2D image includes associated 3D information. The method includes an operator determining a geometric primitive corresponding to shape characteristics of the object and then the generation of the 3D model based on the determined geometric primitive, the 2D image, and the associated 3D information. | 01-08-2009 |
20080307549 | Polysaccharide Synthases - The present invention relates generally to polysaccharide synthases. More particularly, the present invention relates to (1,3;1,4)-beta-D-glucan synthases. The present invention provides, among other things, methods for influencing the level of (1,3;1,4)-beta-D-glucan produced by a cell and nucleic acid and amino acid sequences which encode (1,3;1,4)-beta-D-glucan synthases. | 12-11-2008 |
20080291949 | Q-Switched Laser - A system for producing a laser light pulse is disclosed. The system includes a travelling wave or ring laser incorporating a gain medium with polarizing means for introducing substantially polarized radiation having a first polarization state into the travelling wave laser and output coupling means to substantially output couple radiation having an output polarization state from the travelling wave laser. The system further includes polarization changing means incorporated into the optical path of the travelling wave laser for changing the polarization of radiation having the first polarization state to a seeding polarization state, wherein radiation with the seeding polarization state seeds the gain medium, and radiation intensity modulation means for modulating the intensity of radiation in the travelling wave laser to vary the feedback of radiation into the gain medium, wherein the radiation intensity modulation means also modulates the radiation with respect to the output coupling means. | 11-27-2008 |
20080274963 | Modulation of Granulosa Cell Apoptosis - The present invention relates to a method of modulating apoptosis of a granulosa cell. The method includes one or more of the following steps: (i) modulating the concentration and/or activity of BMP-15 and/or BMP-6 that the granulosa cell is exposed to; (ii) modulating activity of a BMP-15 dependent signalling pathway in the granulosa cell; and (iii) modulating activity of a BMP-6 dependent signalling pathway in a granulosa cell. | 11-06-2008 |
20080241824 | Mutation Associated With Lacunar Strokes - The present invention relates to a method of identifying a subject predisposed to lacunar stroke. The method includes the step of identifying in the subject the presence of a thymine to cytosine mutation at position -107 in both alleles of the paraoxonase 1 locus. | 10-02-2008 |