The Queen's Medical Center Patent applications |
Patent application number | Title | Published |
20140100552 | VASCULAR ACCESS SYSTEMS HAVING A GUIDEWIRE ANTI-MIGRATION FEATURE - Disclosed herein is a removable cap for connection to an input port of a catheter, comprising a proximal end having a lumen configured to house a guidewire therethrough; a distal end configured to reversibly mate with a luer lock of the input port of a catheter, the distal end having a lumen configured to house the guidewire therethrough; and a tubular body between the proximal end and the distal end, wherein the tubular body comprises an anti-migration feature transformable between a first configuration to allow slidable movement of the guidewire within the cap in a first direction toward the patient, and a second configuration to prevent slidable movement of the guidewire within the cap in the first direction toward the patient. Systems and methods are also disclosed. | 04-10-2014 |
20140037174 | MOTION TRACKING SYSTEM FOR REAL TIME ADAPTIVE IMAGING AND SPECTROSCOPY - This invention relates to a system that adaptively compensates for subject motion in real-time in an imaging system. An object orientation marker ( | 02-06-2014 |
20130188830 | MOTION TRACKING SYSTEM FOR REAL TIME ADAPTIVE IMAGING AND SPECTROSCOPY - This invention relates to a system that adaptively compensates for subject motion in real-time in an imaging system. An object orientation marker ( | 07-25-2013 |
20110230368 | High Throughput Assays for TRPM7 - The present invention provides high throughput assays for TRPM7 activity. The present invention encompasses methods and compositions for screening a sample for inhibitors of TRPM7, including methods and compositions for competitive high throughput assays. | 09-22-2011 |
20110028725 | Preparation and Use of Alkylating Agents - The present disclosure provides methods of synthesizing alkylating agents and methods of use. | 02-03-2011 |
20090209435 | Methods of screening for TRPM4b modulators - The invention relates, in part, to methods useful in identifying molecules, that bind TRPM4b, which modulate TRPM4b ion channel activity, and/or which alter expression of TRPM4b within cells. The TRPM4b channels as described herein contain TRPM4b polypeptides, which are in turn encoded by TRPM4b nucleic acids. The ion channels described herein are preferably formed in HEK-293 cells from one or more novel TRPM4b polypeptides, which exhibit one or more of the unique TRPM4b properties described herein. | 08-20-2009 |
20090098546 | Methods of Screening for LTRPC7 Modulators - The present invention relates to the identification and isolation of a novel family of ATP regulated calcium transmembrane channel polypeptides designated herein as “LTRPC7” (Long Transient Receptor Potential Channel). Channels comprising these polypeptides close in response to concentrations of cytoplasmic ATP in the millimolar range, are subject to inhibition by high intracellular levels of calcium and/or magnesium, and do not respond to depletion or reduction in intracellular calcium stores. The invention further relates to the methods of utilizing LTRPC7 for binding, and the methods for modulating LTRPC7 activity and for measuring LTRPC2 permeability. The invention further relates to the methods of modulating expression of LTRPC7. | 04-16-2009 |
20090053753 | FUNCTIONAL IDENTIFICATION OF PROTEINS UNDERLYING Icrac ACTIVITY IN A CELL - The invention provides methods and compositions for determining the identity of CRACM homologs underlying Icrac activity in cells. | 02-26-2009 |
20090023177 | ASSAYS AND METHODS FOR DETERMINING STIM2 ACTIVITY - The present invention provides assays and methods for determining levels of STIM2 activity, thus providing tools for the characterization and study of the regulation of intracellular calcium levels. | 01-22-2009 |
20080294289 | Preparation and Use of Alkylating Agents - The present disclosure provides methods of synthesizing alkylating agents and methods of use. | 11-27-2008 |