Introgen Therapeutics, Inc.
Introgen Therapeutics, Inc. Patent applications | ||
Patent application number | Title | Published |
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20090253184 | COMPOSITIONS AND METHODS RELATED TO AN ADENOVIRAL TRANS-COMPLEMENTING CELL LINE - Embodiments of the invention include E1 expressing cell lines that can be used in a variety of methods for production of an E1 defective adenovirus. In certain aspects a cell of the invention can be adapted to various culture conditions, e.g., suspension culture in serum free medium. In a further aspect, the cell lines allow isolation and subculture of E1-deleted recombinant adenoviruses in an environment free of replication competent adenovirus (RCA). | 10-08-2009 |
20080293652 | Combination of Ad-P53 and Chemotherapy for the Treatment of Tumours - The present invention relates to the use of p53 gene therapy to treat recurrent cancers in combination with a radio- or chemotherapy. Patients with recurring cancers are treated with a p53 expression construct followed by subsequent radio- or chemotherapy treatment. Viral and non-viral delivery systems, as well as various radio- and chemotherapy regimens are disclosed. | 11-27-2008 |