UNIVERSITETET I OSLO Patent applications |
Patent application number | Title | Published |
20150133510 | TERTIARY AMINES FOR USE IN THE TREATMENT OF CARDIAC DISORDERS - The present invention relates to tertiary amines of formula (I) for use in therapy, particularly for use in treating cardiovascular disorders. The compounds have been found to regulate phospholamban phosphorylation by interfering with the A-kinase anchor protein 18delta (AKAP185) binding to the PKA substrate phospholamban. The compounds share a tri(alkylaryl/alkylheteroaryl)amine structure. | 05-14-2015 |
20150132391 | COMPOSITION COMPRISING NANOPARTICLES OF TI02 - The present invention is directed to a composition comprising nanoparticles of TiO | 05-14-2015 |
20150068597 | SURFACE PASSIVATION OF SILICON BASED WAFERS - The surface recombination velocity of a silicon sample is reduced by deposition of a thin hydrogenated amorphous silicon or hydrogenated amorphous silicon carbide film, followed by deposition of a thin hydrogenated silicon nitride film. The surface recombination velocity is further decreased by a subsequent anneal. Silicon solar cell structures using this new method for efficient reduction of the surface recombination velocity is claimed. | 03-12-2015 |
20140349315 | DISULPHIDE BOND-STABILIZED FUNCTIONAL SOLUBLE MHC CLASS II HETERODIMERS - The present invention relates to disulphide bond stabilized recombinant MHC class II molecules. In particular, the present invention provides a recombinant MHC class II molecule, which comprises: (i) all or part of the extracellular portion of an MHC class II α chain; (ii) all or part of the extracellular portion of an MHC class II β chain; wherein (i) and (ii) provide a functional peptide binding domain and wherein (i) and (ii) are linked by a disulphide bond between cysteine residues located in the α2 domain of said α chain and the β2 domain of said β chain, wherein said cysteine residues are not present in native MHC class II α2 and β2 domains. Methods of producing these molecules in prokaryotic systems and various uses of these molecules form further aspects. | 11-27-2014 |
20140322123 | METAL ORGANIC FRAMEWORK COMPOUNDS - The invention provides novel Zr MOFs, in particular compounds having a surface area of at least 1020 m | 10-30-2014 |
20140119627 | Method for improved estimation of tracer uptake in physiological image volumes - A method of estimating the true uptake of a tracer in a physiological image acquired with a physiological image modality that has limited spatial resolution comprises: co-registering an anatomical image volume and the physiological image volume such that both image volumes have corresponding voxels; segmenting the anatomical image volume into a number of non-overlapping anatomical regions; combining each of the segmented anatomical regions with a function representative of the limited spatial resolution of the physiological image modality to generate a blurred anatomical region volume for each of the segmented regions; assuming the physiological image in each voxel to be a linear sum of the image intensities of the corresponding voxels in the blurred region volumes in that voxel; estimating, for each voxel, a value representative of the contribution to that voxel from each blurred region volume based on the uptake measured by the physiological image for that voxel and for nearby voxels; and using the estimated values for the voxels to estimate a true uptake of the tracer in each voxel and to thereby establish a corrected physiological image volume. | 05-01-2014 |
20140113301 | DETECTION OF SAXITOXIN-PRODUCING DINOFLAGELLATES - The current disclosure generally relates to the field of saxitoxins and the identification of microorganisms capable of producing them. In particular, the saxitoxin A (sxtA) gene comprising catalytic domain sequences saxitoxin A1 (sxtA1) and saxitoxin A4 (sxtA4) is identified in a number of dinoflagellate species. The disclosure relates to methods of detection of saxitoxin-producing dinoflagellates by amplification and detection of the sxtA gene (in particular by PCR) and kits and primers for use in the method are also disclosed. Saxitoxin-producing dinoflagellate genera detected by the method include | 04-24-2014 |
20130171668 | DISULPHIDE BOND-STABILIZED FUNCTIONAL SOLUBLE MHC CLASS II HETERODIMERS - The present invention relates to disulphide bond stabilized recombinant MHC class II molecules. In particular, the present invention provides a recombinant MHC class II molecule, which comprises: (i) all or part of the extracellular portion of an MHC class II α chain; (ii) all or part of the extracellular portion of an MHC class II β chain; wherein (i) and (ii) provide a functional peptide binding domain and wherein (i) and (ii) are linked by a disulphide bond between cysteine residues located in the α2 domain of said α chain and the β2 domain of said β chain, wherein said cysteine residues are not present in native MHC class II α2 and β2 domains. Methods of producing these molecules in prokaryotic systems and various uses of these molecules form further aspects. | 07-04-2013 |
20130034499 | SGII AS A PROGNOSTIC MARKER IN CONDITIONS WHICH REQUIRE CRITICAL CARE - The present invention relates to methods for determining the prognosis of a condition which requires critical care, said methods comprising determining the level of SgII, or fragments thereof in a subject. The methods of the invention can also be used to determine whether an individual is suffering from a condition which requires critical care and determining the severity of a condition which requires critical care. | 02-07-2013 |
20120115961 | METAL ORGANIC FRAMEWORK COMPOUNDS - The invention provides novel Zr MOFs, in particular compounds having a surface area of at least 1020 m | 05-10-2012 |
20110263479 | Peptides - A peptide which can adopt a 3 | 10-27-2011 |
20110223106 | GRANIN PROTEINS AS MARKERS OF HEART DISEASE - The present invention relates to methods for the diagnosis of impaired cardiac function/heart disease. The present invention provides a method of diagnosing heart disease in a subject, said method comprising determining the level of CgB or SgII, or fragments thereof, in a body fluid of said subject. Such methods can also be used to determine the clinical severity or prognosis of heart disease in a subject. | 09-15-2011 |
20110099798 | FORMATION OF A LITHIUM COMPRISING STRUCTURE ON A SUBSTRATE BY ALD - The present invention discloses a method for the formation of lithium comprising layer on a substrate using an atomic layer deposition method. The method comprises the sequential pulsing of a lithium precursor through a reaction chamber for deposition upon a substrate. Using further oxidising pulses and or other metal containing precursor pulses, an electrolyte suitable for use in thin film batteries may be manufactured. | 05-05-2011 |
20110018687 | ULTRASOUND ZONE LOCATION SYSTEM WITH HIGH CAPACITY - A zone location system with ultrasound US transmitters S | 01-27-2011 |
20100137266 | TREATMENT OF INSULIN RESISTANCE AND DISORDERS ASSOCIATED THEREWITH - The present invention provides the use of an LXR antagonist, or a physiologically-acceptable pro-drug therefor, in the manufacture of a medicament for combating insulin resistance or a disorder associated therewith. Further provided is a compound being an ester or carbamate of a hydroxycholesterol, a pharmaceutical composition of such a compound or its use in therapy. | 06-03-2010 |
20100064367 | INTRUSION DETECTION FOR COMPUTER PROGRAMS - A method of detecting intrusion in a computer program which has number of defined libraries and includes cross border instructions which cause execution to branch from a source library to a target library. The method comprises the step of determining whether execution of the program is in an area consistent with normal execution of the program, by checking whether the source library of a cross border instruction is the expected current execution library of the program. Each cross border instruction has a code stub identifying the source library, and when a legal cross border instruction is executed the target library becomes the current execution library. The method also checks that the target address of a cross border instruction is a legal address. In another arrangement, areas of the program are set so that a cross border instruction will generate page protection fault which is intercepted by the intrusion detection system so that the cross border instruction can be checked. | 03-11-2010 |
20090286674 | ACTIVATION OF SURFACES THROUGH GAS PHASE REACTIONS - A process for the preparation of active surfaces terminated by a desired form of organic, organic-inorganic, or inorganic nature comprising growing with a gas phase deposition technique preferable the ALCVD (atomic layer chemical vapour deposition) technique. As an example, trimethylaluminium (TMA), hydroquinone (Hq) and phloroglucinol (Phl) have been used as precursors to fabricate surfaces that are terminated by hydroxyl groups attached to aromates. Further types of active surfaces are described. These surfaces can be used to produce surfaces: suitable for adhesion through the use of glue or other adhesive, providing receptors for biological molecules, making the surfaces biocompatible, of catalytically active materials, where upon subsequent types of chemical reactions can take place, with different degrees of wetting properties. | 11-19-2009 |
20090104500 | Proton Conductors - Proton conductivity has been shown in acceptor-doped rare earth orthoniobates and tantalates (LnNbO | 04-23-2009 |
20090056800 | Surface Passivation of Silicon Based Wafers - The surface recombination velocity of a silicon sample is reduced by deposition of a thin hydrogenated amorphous silicon or hydrogenated amorphous silicon carbide film, followed by deposition of a thin hydrogenated silicon nitride film. The surface recombination velocity is further decreased by a subsequent anneal. Silicon solar cell structures using this new method for efficient reduction of the surface recombination velocity is claimed. | 03-05-2009 |
20080306315 | Metal-Organic Framework Catalysts and Their Use in Hydrocarbon Transformation - The invention relates to a porous heterogeneous catalyst material comprising frameworks of inorganic cornerstones connected by organic bridges, characterized in that as organic bridges are used ligands having a complexed catalytically active metal. The metals are preferably palladium and platinum. The ligands preferably contain nitrogen donor groups for complexing the catalytically active metal and carboxylate groups connecting to the inorganic cornerstones. | 12-11-2008 |
20080281523 | CHANNEL IMPULSE RESPONSE ESTIMATION - A method of estimating the impulse response of a channel is disclosed. The method includes transmitting an impulse signal to the channel, detecting a received signal from the channel, and calculating an estimate of the impulse response of the channel by applying a calculated inverse matrix of the impulse signal to the received signal. | 11-13-2008 |