THE CURATORS OF THE UNIVERSITY OF MISSOURI Patent applications |
Patent application number | Title | Published |
20160120016 | LOW-POWER, COMPACT PIEZOELECTRIC PARTICLE EMISSION - A low-power, compact piezoelectric particle emitter for emitting particles such as X-rays and neutrons. A piezoelectric transformer crystal receives an input voltage at an input end and generates a higher output voltage at an output electrode disposed at an output end. The emitter is in a vacuum and the output voltage creates an electric field. A charged particle source is positioned relative a target such that charged particles from the charged particle source are accelerated by the electric field toward the target. Interaction between the accelerated charged particles and the target causes one of X-rays and neutrons to be emitted. | 04-28-2016 |
20160090444 | DRUG LOADING PENTABLOCK POLYMERS - Novel pentablock polymers having a PCL-PLA-PEG-PLA-PCL or PCL-PGA-PEG-PGA-PCL configuration, wherein PEG is polyethylene glycol, PCL is poly(8-caprolactone), PGA is poly(glycolic acid), and PLA is poly(lactic acid), and methods of making nanoparticles from the pentablock polymers, are disclosed. The invention is also directed to a method for preparing nanoparticle compositions comprised of polymers with high levels of bioactive or diagnostic agents. | 03-31-2016 |
20160083408 | ARSENIC COMPLEXES FOR POTENTIAL DIAGNOSTIC APPLICATIONS - The present invention provides radioactive arsenic complexes useful in diagnostic and therapeutic applications and methods for forming those arsenic complexes. | 03-24-2016 |
20160081591 | System and Method for Laryngeal Reflex Examination - A system for elucidating physiological characteristics of laryngeal adductor reflex (LAR) responses in a human or animal subject's larynx's vocal folds (VFs) includes a pressure pulsing component to provide a stable and adjustable pulse of pressure to the larynx, a control system component in functional communication with the pressure pulsing component to control or regulate one or more aspects of the timing, magnitude and number of pulses of pressure delivered by the pressure pulsing component during respiratory cycles, and a respiratory sensor component to detect and/or determine physiological characteristics of the subject's LAR response. The method includes evoking a LAR response in the subject and determining one or more physiological measurements including duration, velocity, and angles of motion of the subject's VFs during the LAR response. The present disclosure provides for enhanced endoscopic field of view of the larynx and delivering stimuli over a wider range of controlled parameters. | 03-24-2016 |
20160074151 | SYSTEMS AND METHODS FOR ALIGNMENT AND SITE PREPARATION OF ROTATOR CUFF GRAFTS - A graft-positioning system that includes a body further comprising a shaft, a handle engaged to the first end of the shaft, a guide rest engaged to the second end of the shaft and a flange engaged to the guide. In addition, the shaft also includes a plurality of pin channels that extend from the first end to the second end of the shaft. The graft-positioning system may also include plurality of guide pins that are configured and arranged to be received within the plurality of pin channels. Additional embodiments provide an arthroscopic cutter that includes a tubular body and a drive shaft attached to a cutting head at one end and situated within a lumen defined within the tubular body. The tubular body further includes a guide rest engaged to the distal end of the tubular body and a flange engaged to the guide rest. | 03-17-2016 |
20160045874 | NANOCOMPOSITE MEMBRANES WITH ADVANCED ANTIFOULING PROPERTIES UNDER VISIBLE LIGHT IRRADIATION - Nitrogen doped TiO | 02-18-2016 |
20160041188 | PEPTIDE WITH GOLD BINDING AND EGFR RECEPTOR AFFINITY AND SAME ATTACHED TO GOLD NANOSTRUCTURE - An embodiment of the invention is a peptide comprising four domains, wherein domain I consists of thioctyl or monocytl, domain II consists of 2 to 3 positively charged amino acids selected from the group consisting of lysine and arginine, domain III consists of a dimeric ethylene unit; and domain IV comprises the peptide with SEQ ID No. 1 or a sequence having at least 90% identity to SEQ ID No. I. The peptide is preferably attached to a gold nanostructure, preferably a gold nanorod to provide an EFGR kit. An EFGR detection kit of the invention employs a gold nanostructure attached to a peptide sequence, the peptide sequence includes a binding sequence with an affinity toward EGFR, a ligand bound to gold atoms of the nanorod, a positively charged amino acid that maintains activity of the binding sequence, and a unit that increases hydrophilicity of the peptide sequence. | 02-11-2016 |
20160032366 | MULTIPLEX ASSAY FOR DETECTION OF BACTERIAL SPECIES IN BIOLOGICAL SAMPLES - The invention provides a rapid, accurate, sensitive, and low-cost detection method for screening a biological sample for one or more desired bacterial species. The inventive method employs a two-step multiplex real-time PCR assay that comprises an internal amplification control and specific primer sets to detect and discriminate bacterial species based the unique melting temperatures of specific DNA sequences of each strain. | 02-04-2016 |
20160032315 | SOYBEAN RESISTANT TO CYST NEMATODES - A transgenic soybean resistant to soybean cyst nematode (SCN), or parts thereof, including an artificial DNA construct encoding a serine hydroxymethyltransferase protein (e.g., GmSHMT). Also provided are GmSHMT alleles containing mutations R130P and Y358N along with research and breeding methods and compositions including such. | 02-04-2016 |
20160031912 | CLUSTER BORON COMPOUNDS AND USES THEREOF - The present invention relates to novel cluster boron compounds and their use as sodium channel blockers. The invention also provides methods for making and using the compounds. | 02-04-2016 |
20150351841 | GUIDED WAVE ABLATION AND SENSING - Systems and methods for the controlled delivery of laser light to target tissue using an improved waveguide. A waveguide controls transmission of wave energy to a target based on direct contact with the target. The waveguide comprises a propagation medium, a cladding causing the electromagnetic wave to be internally reflected in the medium, and an interface formed in the cladding and configured for direct contact with the target. A portion of the laser light penetrates through the cladding at the interface and propagates into the target while a portion internally reflects within the propagation medium. | 12-10-2015 |
20150335768 | ErbB-2 RECEPTOR TARGETING PEPTIDE - The ErbB-2 receptor, a member of the tyrosine kinase type 1 family of receptors, has been implicated in many human malignancies. Bacteriophage display technology was employed to identify peptides that bound to the extracellular domain of human ErbB-2. The peptide KCCYSL, most frequently occurring in the affinity selected population, was chemically synthesized and characterized for its binding activities to the recombinant extracellular domain of ErbB-2. The synthetic peptide exhibits high specificity to ErbB-2 as well as to ErbB-1, another member of ErbB family. Thus, this peptide can be employed in cancer imaging or therapeutic agent targeting to malignant cells ErbB-2 receptor. | 11-26-2015 |
20150328314 | PHOTOCLEAVABLE DRUG CONJUGATES - Novel photocleavable drug conjugates for forming drug depots comprise drugs attached to photocleavable groups. In one embodiment, the drug is linked via photocleavable group(s) to a polymer chain to form a photocleavable drug-polymer conjugate that generally forms the depot matrix. In another embodiment, the drug is crosslinked via photocleavable group(s) to themselves to form a photocleavable drug conjugate that generally forms the depot. | 11-19-2015 |
20150283274 | RADIOISOTOPE TRITHIOL COMPLEXES - The present invention is directed to a series of stable radioisotope trithiol complexes that provide a simplified route for the direct complexation of radioisotopes present in low concentrations. In certain embodiments, the complex contains a linking domain configured to conjugate the radioisotope trithiol complex to a targeting vector. The invention is also directed to a novel method of linking the radioisotope to a trithiol compound to form the radioisotope trithiol complex. The inventive radioisotope trithiol complexes may be utilized for a variety of applications, including diagnostics and/or treatment in nuclear medicine. | 10-08-2015 |
20150266983 | FLEXIBLE TO RIGID NANOPOROUS POLYURETHANE-ACRYLATE (PUAC) TYPE MATERIALS FOR STRUCTURAL AND THERMAL INSULATION APPLICATIONS - Novel urethane-acrylate (UAC) Star monomers and polyurethane-acrylate (PUAC) aerogel polymers derived therefrom are described herein, along with other novel, related monomers and polymers. Also described herein are processes for preparing the UAC Star monomers, the PUAC aerogel polymers, and the other related monomers and polymers. The PUAC and related polymers herein are useful in various applications including in structural and thermal insulation. | 09-24-2015 |
20150221405 | METHOD AND APPARATUS FOR GENERATING NEUTRONS FROM METALS UNDER THERMAL SHOCK - A method and apparatus for generating neutrons by inducing hydride-forming metals infused with hydrogen isotopes to undergo rapid phase transitions. Such transitions are induced by exposing the metals to rapid temperature changes. The method includes placing the metals in a high-pressure reaction chamber, introducing a hydrogen isotope gas into the chamber to produce a metal hydride, reducing the temperature of the pressure chamber to maximize infusion of gas into metal, then quickly heating the reaction chamber, such that the temperature of the interior of the reaction chamber rapidly rises from a minimum temperature to a maximum temperature in an amount of time that is less than a thermal shock period. The temperatures and pressures are at such high levels that if two or more hydrogen isotope atoms are in the same void or defect within a crystalline lattice of the metal hydride, the atoms can react, resulting in neutron generation. | 08-06-2015 |
20150150153 | ARTIFICIAL OOCYTE ACTIVATION - The present invention provides novel methods for improving the efficiency of artificial activation of unfertilized mammalian oocytes by reducing the intracellular concentration of Zn | 05-28-2015 |
20150126564 | MODULATION OF SPHINGOSINE 1-PHOSPHATE METABOLIZING ENZYMES FOR THE TREATMENT OF NEGATIVE-STRAND RNA VIRUS INFECTIONS - The present invention relates to compounds and methods for the prevention or treatment of infections by negative strand RNA viruses, such as influenza virus and measles virus, wherein said compounds delay or inhibit viral replication by modulating the level or activity of a polypeptide involved in the synthesis or degradation of sphingosine-1-phosphate (S1P) in a cell, tissue, or subject. The methods involve administration of one or more compounds which modulate the level of gene expression, where the gene encodes a polypeptide involved in regulating the metabolic level of S1P, or modulate the level or activity of a polypeptide involved in regulating the metabolic level of S1P, such as sphingosine kinase (SK) and S1P lyase (SPL). Exemplary methods are directed towards reducing the level of SW by reducing the level or activity of one or more SKs, increasing the level or activity of one or more SPLs, or a combination of both steps. | 05-07-2015 |
20150125780 | VISCOUS SEALING GLASS COMPOSITIONS FOR SOLID OXIDE FUEL CELLS - A sealant for forming a seal between at least two solid oxide fuel cell components wherein the sealant comprises a glass material comprising B | 05-07-2015 |
20150112377 | EMBOLIC PROTECTION SYSTEM - A collapsible blood filtering aortic arch bridge comprising a dumbbell shaped chassis having a tubular waist, a first conical end, and a second conical end such that only a periphery of the first and second ends contact the intima of an aortic arch when the bridge is disposed and expanded within the aortic arch of a patient. The waist is flexible so that the bridge can bend to comply with the curvature of the aortic arch. The bridge additionally comprises a blood filtering sleeve disposed over an interior or an exterior of the chassis for filtering blood flowing through the bridge into aortic arch vessels of the patient when the bridge is disposed within the aortic arch. Furthermore, the bridge comprises a retrieval sleeve disposed over the exterior of the chassis for collapsing the bridge to a cylindrical form for retrieval of the bridge from the aortic arch. | 04-23-2015 |
20150077138 | WAVEGUIDE PROBE FOR NONDESTRUCTIVE MATERIAL CHARACTERIZATION - An open-ended waveguide probe including a finite flange extending outwardly and functioning as an infinite flange. A signal source provides a microwave signal to the waveguide, which in turn transmits microwave electromagnetic energy incident upon an object to be tested. The finite flange at the waveguide's aperture is shaped to reduce scattering of the electromagnetic field reflected from the object and received by the aperture. The probe is adapted for coupling to a receiver for sampling the reflected electromagnetic field received by the aperture and the receiver is adapted for coupling to a processor for determining at least one material characteristic of the object based on sampled electromagnetic field reflected from the object. | 03-19-2015 |
20150072956 | CLUSTER BORON COMPOUNDS AND USES THEREOF - The present invention relates to novel cluster boron compounds and their use as sodium channel blockers. In particular, the novel cluster boron compounds may be lidocaine analogs where the aromatic ring of the lidocaine molecule is replaced with a cluster boron group. The invention also provides methods for making the cluster boron compounds comprising contacting a halogenated cluster boron with an amino acetamide in the presence of a catalyst, a proton acceptor, and a ligand. | 03-12-2015 |
20150059022 | Genes Controlling Plant Root Growth and Development for Stress Tolerance and Method of Their Use - Microarrays are employed to analyze soybean transcriptome under water stress conditions in different regions of the root at vegetative stage. Drought responsive genes and transcription factors are identified which may be used for enhancing drought tolerance in soybean or other plants through genetic/metabolic engineering. This disclosure pertains to nucleic acid molecules isolated from soybean and maize that encode polypeptides that may be important for drought tolerance. The disclosure also relates to methods of using these genes from soybean in transgenic plants to confer the desired agronomic traits, and to use such genes or regulatory elements thereof to assist germplasm enhancement by molecular breeding or to identify other factors or chemicals that may enhance a plant's capability to grow under drought conditions. | 02-26-2015 |
20150056595 | SYSTEMS AND METHODS FOR DIAGNOSIS AND TREATMENT OF PSYCHIATRIC DISORDERS - A device for diagnosing and treating psychiatric disorders is described. The device may be configured to provide a graphical user interface that enables a user to select at least one of: entering information related to a diagnosis of the psychiatric disorder and alleviating symptoms caused by the psychiatric disorder. Upon a user selecting entering information related to the diagnosis of a psychiatric disorder, the device may receive information related to the diagnosis of the psychiatric disorder. The device may determine the severity of a user's condition based at least in part on the received information. The device may provide a treatment based on the determined severity of the user's condition. A treatment may include providing feedback to a user. | 02-26-2015 |
20140380522 | SOYBEAN RESISTANT TO CYST NEMATODES - A transgenic soybean plant or parts thereof, resistant to soybean cyst nematodes, transformed to express Glyma18g02570, Glyma18g02580, or Glyma18g02590, or a variant thereof. Also provided is a method of making such a plant. Also provided is an artificial DNA construct encoding Glyma18g02570, Glyma18g02580, or Glyma18g02590, or a variant thereof. | 12-25-2014 |
20140369903 | Method and system for purifying charged radioisotopes - The present invention provides a simple and inexpensive method for removing metal and other impurities in a radioisotope solution. The invention further includes the development of a new parent/daughter generator system for collecting the daughter isotope in a concentrated solution. | 12-18-2014 |
20140367326 | THIN-FILM NANO-COMPOSITE MEMBRANE WITH MESOPOROUS SILICA NANOPARTICLES - The present invention is directed to a filtration membrane comprising a thin polymeric membrane film in which mesoporous silica nanoparticles are embedded. The membrane may be a thin-film nanocomposite membrane useful for reverse osmosis or nanofiltration. The present invention is also directed to a filtration membrane comprising a thin polymeric membrane film formed from a solution comprising less than 0.1 wt % mesoporous nanoparticles. | 12-18-2014 |
20140350329 | INORGANIC PYROPHOSPHATE AND USES THEREOF - The present invention provides a new and improved sperm stimulating additive comprising a certain amount of inorganic pyrophosphate (PPi). Addition of PPi in the media for human/animal in vitro fertilization (IVF) improves fertilization rate; addition of PPi in the semen extender for farm animal artificial insemination (AI) may improve pregnancy rates; furthermore, mamalian oocytes matured in vitro in a medium including PPi attain improved fertilization and developmental potential, while embryos cultured in medium supplemented with PPi have improved development to blastocyst. | 11-27-2014 |
20140330305 | EMBOLIC PROTECTION SYSTEM - A collapsible blood filtering aortic arch bridge including an expandable and collapsible chassis structured to provide the bridge with a dumbbell-like shape when expanded having a tubular waist, a first conical end, and a second conical end formed such that only a periphery of the first and second ends contact the intima of an aortic arch when the bridge is disposed within the aortic arch of a patient. The bridge additionally includes a blood filtering sleeve disposed over an interior or an exterior of the chassis that is structured and operable to filter blood flowing through the bridge into aortic arch vessels of the patient when the bridge is disposed within the aortic arch. The bridge further includes a retrieval mechanism structured and operable to collapse the bridge to a cylindrical form for retrieval of the bridge from the aortic arch. | 11-06-2014 |
20140314375 | CAPILLARY WALL COUPLED WHISPERING GALLERY MODE MICRORESONATOR - A microresonator structure comprises a waveguide and a microsphere. The waveguide is of elongated cylindrical shape and includes a first section of optical transmission material and a cavity section axially aligned with the first section. The cavity section includes a first cavity and a second cavity. The first cavity is adjacent to the first section and includes a first sidewall of optical transmission material with an inner surface that tapers inward to an apex positioned adjacent to the first section. The second cavity is positioned adjacent to the first cavity of hollow cylindrical shape and includes a circumferential second sidewall of optical transmission material that abuts the first sidewall. The microsphere has a spherical outer surface and is positioned within the cavity section such that the outer surface contacts a portion of the first sidewall and a portion of the second sidewall. | 10-23-2014 |
20140309129 | Encoded Nanopore Sensor for Multiplex Nucleic Acids Detection - The present invention provides a new and improved multiplexed oligonucleotide detection method based on the nanopore technology with one or more probes containing a sequence with complementarity to the target oligonucleotide, a terminal extension at the probe's 3′ terminus, 5′ terminus, or both termini and a label attached to the terminus. The improved probes and probe sets enable sensitive, selective, and direct multiplex detection, differentiation and quantification of distinct target oligonucleotides such as miRNAs. The inventive detection method may also be employed as a non-invasive and cost-effective diagnostic method based on miRNA levels in the patient's tissue sample. | 10-16-2014 |
20140302104 | CONJUGATED POLYMERIC MATERIAL AND USES THEREOF - Disclosed are compositions comprising collagen covalently bound to particles, wherein covalent bonds are formed between reactive groups of the collagen and reactive groups of the particles, and wherein the particles have an average particle diameter ranging from 20 to 1000 nanometers. Also disclosed are various methods that utilize the compositions. | 10-09-2014 |
20140286945 | ENZYME INHIBITOR FOR CANCER TREATMENT - Disclosed herein is a new and improved therapy for the treatment of diseases including cancer, which comprises the step of altering cell membrane lipid composition by treating a cancer cell with an enzyme inhibitor which inhibits enzymes regulating the cholesterol biosynthetic pathway. The method may also be employed in combination with existing chemotherapeutic agents to combat the drug resistance and enhance the therapeutic efficacy of conventional therapy. | 09-25-2014 |
20140277578 | Biodegradable Composite Scaffold for Repairing Defects in Load-Bearing Bones - A tissue scaffold for repair and regeneration of bone hard tissue or muscle, skin, or organ soft tissue, including load-bearing bone tissue, the scaffold comprising a core of biocompatible, biodegradable inorganic glass fibers; and a biocompatible, biodegradable, flexible polymer film surrounding the core and adhered to the core. | 09-18-2014 |
20140275213 | Methods and Compositions for Plant Pest Control - The present invention comprises methods and compositions for controlling nematode parasitism in host plant. The present invention comprises novel polynucleotides and polypeptides encoded by such polynucleotides comprising one or more nucleic acid sequences disclosed herein having a nucleotide sequence comprising any one of SEQ ID NOs: 1-142, a fragment or variant thereof, or a complement thereof, or a polypeptide sequence comprising any one of SEQ ID NOs: 143-159, a fragment or variant thereof. | 09-18-2014 |
20140262166 | Waste Heat Recovery Apparatus for a Livestock Poultry Barn - Systems and method are provided for recovering heat from waste air being expelled from a livestock poultry barn. A heat recovery unit is specially designed to take advantage of an unused heat source, while avoiding the corrosive effects of waste air from the livestock poultry barn. The novel heat recovery capture heat from the expelled waste air. | 09-18-2014 |
20140256564 | METHODS OF USING HUR-ASSOCIATED BIOMARKERS TO FACILITATE THE DIAGNOSIS OF, MONITORING THE DISEASE STATUS OF, AND THE PROGRESSION OF TREATMENT OF BREAST CANCERS - The present invention relates to methods of identifying gene targets, including methods of using ribonucleoprotein (RNP) immunoprecipitation-microarrays to identify cancer gene targets, such as subsets of RNP-associated mRNAs in breast cancer cell lines. Also presented, are ribonucleotide binding protein-associated biomarkers, panels or sets of ribonucleotide binding protein-associated biomarkers, methods and compositions comprising ribonucleotide-binding protein, associated nucleotides, nucleotide arrays, and kits, plus methods of using HuR-associated biomarkers to facilitate the diagnosis of, monitoring the disease status of, and the progression of treatment of breast cancers to facilitate the diagnosis of and monitoring the disease status or progression of treatment of breast cancers, including drug-resistant breast cancers. | 09-11-2014 |
20140234255 | MICRODYSTROPHIN PEPTIDES AND METHODS FOR TREATING MUSCULAR DYSTROPHY USING THE SAME - According to the embodiments described herein, a series of biological materials for treatment/therapy of DMD and/or BMD through the recovery of sarcolemmal nNOS is provided. The biological material comprises the complete dystrophin repeats R16 and R17 or certain domains, sections, or fragments of the dystrophin repeats R16 and R17. In some aspects, such domains, sections, or fragments may be selected from sequence motifs including dystrophin R17 α1 helix, α2 and α3 helices of both R16 and R17, or a combination thereof. | 08-21-2014 |
20140231321 | FLOW-THROUGH FILTER TO REMOVE ALUMINUM FROM MEDICAL SOLUTIONS - A flow through filter assembly includes a trivalent and tetravalent metal ion capturing agent and a flow controller providing a predetermined flow rate which allows capture of the trivalent and tetravalent metal ions by the capturing agent. | 08-21-2014 |
20140220685 | SELF-ASSEMBLING MULTICELLULAR BODIES AND METHODS OF PRODUCING A THREE-DIMENSIONAL BIOLOGICAL STRUCTURE USING THE SAME - Structures and methods for tissue engineering include a multicellular body including a plurality of living cells. A plurality of multicellular bodies can be arranged in a pattern and allowed to fuse to form an engineered tissue. The arrangement can include filler bodies including a biocompatible material that resists migration and ingrowth of cells from the multicellular bodies and that is resistant to adherence of cells to it. Three-dimensional constructs can be assembled by printing or otherwise stacking the multicellular bodies and filler bodies such that there is direct contact between adjoining multicellular bodies, suitably along a contact area that has a substantial length. The direct contact between the multicellular bodies promotes efficient and reliable fusion. The increased contact area between adjoining multicellular bodies also promotes efficient and reliable fusion. Methods of producing multicellular bodies having characteristics that facilitate assembly of the three-dimensional constructs are also provided. | 08-07-2014 |
20140215657 | Quantitative Trait Loci Associated With Soybean Cyst Nematode Resistance And Methods Of Their Use - Several QTLs that are genetically linked to resistance to soybean cyst nematode (SCN) are disclosed. These QTLs have been mapped to genomic regions on Chrs. 4, 8, 10, 11, 18, and 20 of soybean, G. max. Candidate genes underlying these QTLs as defined by the flanking markers, as well as genetic markers associated with these QTLs are also disclosed. These markers can be utilized for introgressing SCN resistance into non-resistant soybean germplasm. The unique resistance genes can be introduced into a non-resistant plant by marker-assisted selection (MAS) or by transgenic methods. | 07-31-2014 |
20140180414 | SYSTEM, APPARATUS, AND METHOD FOR GRAFTING TISSUE - Systems, apparatus, and methods may be adapted for grafting tissue at a tissue site that may include an elongate housing and a plurality of elongate cutting members. The plurality of elongate cutting members may define a cutting surface at a distal end of the elongate housing. The cutting surface may be adapted to contract from a first diameter to a second diameter that is less than the first diameter. The contraction of the cutting surface from the first diameter to the second diameter may define a tapered profile between the first diameter and the second diameter suitable for obtaining a tapered graft. | 06-26-2014 |
20140166664 | Conformal Tank For Adsorbant Natural Gas Storage - The present disclosure provides a conformal tank for adsorbent storage of gas. The tank includes a body having a substantially flat top wall, a substantially flat bottom wall and a pair of opposing sidewalls that join the top wall and bottom wall to form an open-ended cuboid having a first open end and an opposing second open end. The tank additionally includes a first end cap connected to the top wall, bottom wall and sidewalls at the first open end, and a second end cap connected to the top wall, bottom wall and sidewalls at the second open end, thereby defining an internal cavity in which gas can be removably stored. The tank further includes a plurality of wall supports connected the top and bottom walls to prevent deformation of the tank. The wall supports are structured to allow gas to move throughout the entire internal cavity of the tank. | 06-19-2014 |
20140165227 | PLANT GENES ASSOCIATED WITH SEED OIL CONTENT AND METHODS OF THEIR USE - Cytochrome b5 (Cb5) is a haem-binding protein located in the endoplasmic reticulum (ER) and the outer mitochondrial membranes of higher eukaryotes. In higher plants, animals, and fungi, the ER resident Cb5 has been shown to play a role in desaturation of acyl CoA fatty acids. Higher plants Cb5 isoforms from plants such as soybean or | 06-12-2014 |
20140162310 | RAPID DETECTION OF VIABLE BACTERIA SYSTEM AND METHOD - An improved system and method is provided for detecting viable bacteria in a suspension sample. A sample of a suspension in which bacterial presence is suspected is collected from a source and a portion of the sample transferred to a microfluidic unit. A series of analysis signals at different frequencies are applied to the sample portion. An impedance is measured via a signal analyzer for the sample portion for each of the analysis signals to define an impedance data set. An initial bulk capacitance value is determined for a model circuit based on the impedance dataset. After a predetermined time period, a new bulk capacitance value is determined for on another portion of the sample. The difference between the new bulk capacitance and the initial bulk capacitance value is compared to a threshold value to determine if viable bacterial is present in the sample. | 06-12-2014 |
20140159541 | HIGH ENERGY-DENSITY RADIOISOTOPE MICRO POWER SOURCES - A solid-state high energy-density micro radioisotope power source device including a dielectric and radiation shielding body having an internal cavity, a first electrode disposed a first end of the cavity, and a second electrode disposed at an opposing second end of the cavity and spaced apart from the first electrode such that a micro chamber is provided therebetween. The device further includes a solid-state composite voltaic semiconductor disposed within the micro chamber fabricated by combining at least one semiconductor material with at least one radioisotope material to provide a pre-voltaic semiconductor composition; depositing the pre-voltaic semiconductor composition into the micro chamber; heating the body to liquefy the pre-voltaic semiconductor composition within the micro chamber such that the semiconductor and radioisotope materials are uniformly mixed; and cooling the body and liquid state composite mixture such that liquid state composite mixture solidifies to provide the solid-state composite voltaic semiconductor. | 06-12-2014 |
20140148733 | ACTIVITY ANALYSIS, FALL DETECTION AND RISK ASSESSMENT SYSTEMS AND METHODS - A method for performing health risk assessments for a patient in a home or medical facility is provided. In various embodiments, the method comprises compiling depth image data from at least one depth camera associated with a particular patient, and generating at least one three-dimensional object based on the depth image data. The method additionally includes identifying a walking sequence from the at least one three-dimensional object, analyzing the walking sequence to generate one or more parameters, and performing at least one health risk assessment based on the one or more parameters to determine a health risk assessment score. The method further comprises sending an alert message to at least one caregiver when the at least one health risk assessment indicates the occurrence of an incident (i.e., the recorded depth image data) denoting that the patient has fallen or that there exists a high risk of the patient falling. | 05-29-2014 |
20140125516 | THREE-DIMENSIONAL HOLOGRAPHICAL IMAGING - A holographic imaging system including a transmission line coupled to an antenna at one end and to a signal source at another end. The antenna defines an aperture through which a signal generated by the signal source is transmitted incident to an object located remotely from the aperture and through which a signal reflected from the object is received by the antenna aperture. A standing wave probe phase-referenced to the antenna aperture samples the reflected signal. A detector connected to the standing wave probe receives the sampled reflected signal and provides an output signal that represents a real-valued signal proportional to an in-phase component of the reflected signal from the object. A processor executes an imaging algorithm for generating a multi-dimensional profile representative of the object based on the output signal from the detector. | 05-08-2014 |
20140111374 | FREE-HAND SCANNING AND IMAGING - Wideband synthetic aperture radar (SAR) imaging. A probe transmits a signal through its aperture incident to an object located in a medium of interest remotely from the probe. The probe receives through the aperture a plurality of nonuniformly sampled reflected signals from the object as the probe moves in a measurement plane located a predetermined distance from the object. A processor executes a SAR-based reconstruction algorithm to generate an image. | 04-24-2014 |
20140106988 | Addressable Electrode Arrays in Multiple Fluidic Compartments and Uses Thereof - Methods and apparati for performing measurements of electrical signals in a multi-compartmented fluidic array format where the signal to noise ratio is improved are disclosed. | 04-17-2014 |
20140099675 | REUSABLE PCR AMPLIFICATION SYSTEM AND METHOD - A DNA amplification device utilizing a polydimethylsiloxane (PDMS) and silicon substrate coated with spin-on glass (SOG) is provided. This PDMS layer is irreversibly bonded to the SOG layer of the silicon substrate using oxygen plasma. The amplification device is an inexpensive, microfluidic device, which can be utilized as a portable thermo-cycler to perform PCR amplification of DNA in the field. | 04-10-2014 |
20140096275 | PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS RESISTANT ANIMALS - The disclosure relates to genetically modified swine wherein at least one allele of a SIGLEC1 gene has been inactivated and/or at least one allele of a CD163 gene has been inactivated. Genetically modified swine having both alleles of the SIGLEC1 gene and/or both alleles CD 163 gene inactivated are resistant to porcine reproductive and respiratory syndrome virus (PRRSV). Methods for producing such transgenic swine are also provided. | 04-03-2014 |
20140093618 | ENGINEERED COMESTIBLE MEAT - Provided are engineered meat products formed as a plurality of at least partially fused layers, wherein each layer comprises at least partially fused multicellular bodies comprising non-human myocytes and wherein the engineered meat is comestible. Also provided are multicellular bodies comprising a plurality of non-human myocytes that are adhered and/or cohered to one another; wherein the multicellular bodies are arranged adjacently on a nutrient-permeable support substrate and maintained in culture to allow the multicellular bodies to at least partially fuse to form a substantially planar layer for use in formation of engineered meat. Further described herein are methods of forming engineered meat utilizing said layers. | 04-03-2014 |
20140091491 | OSTEOCHONDRAL IMPLANTS, ARTHROPLASTY METHODS, DEVICES, AND SYSTEMS - Implants for resurfacing or repairing one or more articular cartilage bearing surfaces of a biological organism include an engineered tissue and a biocompatible porous substrate secured to the engineered tissue for attaching the implant to a native bone of the biological organism. The engineered tissue includes a scaffold containing a biocompatible material, and a plurality of living chondrocytes supported by the scaffold. Methods for culturing chondrocytes for incorporation into a biocompatible implant are provided. A bioreactor for producing functional cartilaginous tissue from a cell-seeded scaffold and a system for producing functional cartilaginous tissue are also provided. | 04-03-2014 |
20140090106 | LYSM RECEPTOR-LIKE KINASES TO IMPROVE PLANT DEFENSE RESPONSE AGAINST FUNGAL PATHOGENS - Perception of chitin fragments (chitooligosaccharides) is an important first step in plant defense response against fungal pathogen. LysM receptor-like kinases (LysM RLKs) are instrumental in this perception process. LysM RLKs also play a role in activating transcription of chitin-responsive genes (CRGs) in plants. Mutations in the LysM kinase receptor genes or the downstream CRGs may affect the fungal susceptibility of a plant. Mutations in LysM RLKs or transgenes carrying the same may be beneficial in imparting resistance against fungal pathogens. | 03-27-2014 |
20140088552 | Intravitreal Injection Device - The present disclosure provides a new and improved intravitreal injection device, which is capable of locating the injection site with precision and reproducibility, ensuring the smooth delivery of medications or other treatments, and reducing potential need contaminations. In various embodiments, the device comprises a head unit and a hollow stem extending orthogonally from a bottom of the head unit. The device additionally includes a locating foot slidingly disposed on a distal end of the stem and a biasing device structured to bias the locating foot toward an extended position. | 03-27-2014 |
20140081340 | Apparatus And Method For Sternal Closure - The present disclosure provides a sternal closure fixation device. The fixation device includes a first sternum implant disposable within an interior cavity of a first half of a severed sternum such that the first implant contacts opposing anterior and posterior faces of the cavity. The fixation device additionally includes, a second sternum implant disposable within an interior cavity of a second half of a severed sternum such that the second implant contacts opposing anterior and posterior faces of the cavity. Furthermore, the fixation device includes a rigid fixation pin sized and structured to be disposed within an internal bore of the first implant and within an internal bore of the second implant, whereby when the first and second halves of the severed sternum are joined together, the first and second halves of the sternum are prevented from shear movement in any direction relative to each other. | 03-20-2014 |
20140080197 | NANOSTRUCTURED CARBON BASED BIOCATALYST FOR REMEDIATION OF ENVIRONMENTAL POLLUTANTS - The present invention provides a series of new and improved compounds/materials as vehicles to delivery degradative enzymes to remove/remedy environmental pollutants. The inventive material comprises a series of amide-functionalized ordered mesoporous carbon (AFOMC), which utilizes chemical conjugation techniques for the tethering of enzymes to the surface of the synthesized AFOMC. The delivery mechanism may be utilized to express a wide variety of toxin-degrading enzymes for removal/remediation of organic pollutants. | 03-20-2014 |
20140067129 | Variable Product Agrochemicals Application Management - Methods and products are provided for facilitating application of variable-product agrochemicals, such as fertilizer, to an application area, such as a field. The fertilizer or agrochemical may include a single fertilizer or agrochemical type or a mixture. In one embodiment, a fertilizer-application area is divided into application cells, and a fertilizer product is determined for each cell, based on zones of the application area with a similar characteristic, such as topographic wetness index levels. Based on a determined product for each cell, instructions for controlling an agrochemical applicator are automatically generated. | 03-06-2014 |
20140063461 | Device to Measure Pupillary Light Reflex In Infants and Toddlers - The present disclosure provides a pupillary light reflex (PLR) system, wherein the PLR system includes a remote tracking and imaging system that is structured and operable to generate and acquire high resolution pupil stimulus and response data from a test subject while the test subject is moving and is disposed a distance from remote tracking and imaging system that is greater than or equal to one-third of a meter. The PLR system additionally includes a computer based system controller that is structure and operable to execute PLR software to control the operation of the remote tracking and imaging system and compute PLR information based on the pupil stimulus and response data acquired as the test subject is moving. | 03-06-2014 |
20140050664 | SOY, LENTIL OR EXTRACT STABILIZED, BIOCOMPATIBLE GOLD NANOPARTICLES - The invention provides stabilized, biocompatible gold nanoparticles that are stabilized with material from soy or lentil plant material or a reactive extract thereof of the plant material. The gold nanoparticles of the invention can be fabricated with an environmentally friendly method for making biocompatible stabilized gold nanoparticles. The nanoparticles can be introduced in vivo to conduct enhanced imaging. The nanoparticles can also be introduced in vivo to conduct therapy. | 02-20-2014 |
20140041076 | METABOLIC ENGINEERING OF PLANTS FOR INCREASED HOMOGENTISATE AND TOCOCHROMANOL PRODUCTION - The invention provides methods and compositions for modifying tocochromanol biosynthesis in plants. The present invention thus surprisingly and beneficially provides for increasing desired tocochromanol compounds in plants and enhancing the nutritional quality of human food and animal feed, without associate deleterious plant phenotypes. | 02-06-2014 |
20140039967 | METHOD OF PREDICTING CROP YIELD LOSS DUE TO N-DEFICIENCY - A method for determining the yield loss of a crop using remote sensor data is described. The yield loss is determined using the reflectivity of green light by the crop canopy measured from remote sensor data such as an aerial photograph that is digitized and spatially referenced to the field's longitude and latitude. Green pixel values from the aerial photograph, expressed relative to green pixel values from well-fertilized areas of the field, are transformed to yield losses using a linear transformation that was developed using empirical data. A similar method is described to determine recommended nitrogen fertilization rates for the crop fields. The yield loss data is useful for nitrogen fertilization management, as it allows a producer of crops to weigh the expense of fertilization against the loss of revenue due to yield loss. | 02-06-2014 |
20140038067 | Cathodes For Lithium-Air Battery Cells With Acid Electrolytes - In various embodiments, the present disclosure provides a layered metal-air cathode for a metal-air battery. Generally, the layered metal-air cathode comprises an active catalyst layer, a transition layer bonded to the active catalyst layer, and a backing layer bonded to the transition layer such that the transition layer is disposed between the active catalyst layer and the backing layer. | 02-06-2014 |
20140037756 | SCAFFOLD FOR TISSUE REGENERATION IN MAMMALS - A three-dimensional scaffold with interconnected pores for repair of tissue comprising a scaffold body for structural support of the tissue scaffold, where the scaffold body comprises scaffold body components bonded to each other and made from component materials comprising about 40 to about 90 wt % B | 02-06-2014 |
20140029709 | METHOD AND APPARATUS FOR GENERATING THERMAL NEUTRONS USING AN ELECTRON ACCELERATOR - Apparatus for generating thermal neutrons includes an electron accelerator for generating an electron beam and a converter for converting the electron beam into photons. A receiving device is provided for receiving the photons and includes a material which provides a photoneutron target for the photons, for producing high energy neutrons in a photonuclear reaction between the photons and the photoneutron target, and for moderating the high energy neutrons to generate the thermal neutrons. The electron beam has an energy level high enough to produce photons of sufficient energy to exceed the photodissociation threshold of the selected target material, but that is sufficiently low as to enable the material to moderate the high energy neutrons resulting from the photonuclear reaction. | 01-30-2014 |
20140017320 | WOUND CARE COMPOSITIONS - A method for treating a wound, and a dressing for wound care management comprising a three-dimensional body of glass-based fibers comprising one or more glass-formers selected from the group consisting of P | 01-16-2014 |
20140017175 | PENTABLOCK POLYMERS - Novel pentablock polymers comprising PGA-PCL-PEG-PCL-PGA or PEG-PCL-PLA-PCL-PEG, wherein PEG is polyethylene glycol, PCL is poly(ε-caprolactone), PGA is poly(glycolic acid), and PLA is poly(lactic acid). | 01-16-2014 |
20140005241 | Suppression of Sars Replication by Sars Helicase Inhibitors | 01-02-2014 |
20140005187 | OXIDOSQUALENE CYCLASE AS A PROTEIN TARGET FOR ANTICANCER THERAPEUTICS | 01-02-2014 |
20130334537 | Optically Controlled Power Devices - An electro-optically triggered power switch is disclosed utilizing a wide bandgap, high purity III-nitride semiconductor material such as BN, AN, GaN, InN and their compounds. The device is electro-optically triggered using a laser diode operating at a wavelength of 10 to 50 nanometers off the material's bandgap, and at a power level of 10 to 100 times less than that required in a conventionally triggered device. The disclosed device may be configured as a high power RF MOSFET, IGBT, FET, or HEMT that can be electro-optically controlled using photons rather than an electrical signal. Electro-optic control lowers the power losses in the semiconductor device, decreases the turn-on time, and simplifies the drive signal requirements. It also allows the power devices to be operated from the millisecond to the sub-picosecond timeframe, thus allowing the power device to be operated at RF frequencies (i.e., kilohertz to terahertz range) and at high temperatures where the bandgap changes with temperature. | 12-19-2013 |
20130326736 | NEMATODE RESISTANT CROPS - Methods of inhibiting plant parasitic nematodes, methods of obtaining transgenic plants useful for inhibiting such nematodes, and transgenic plants that are resistant to plant parasitic nematodes through inhibition of plant nematode CLE peptide receptor genes are provided. Methods for expressing genes at plant parasitic nematode feeding sites with plant nematode CLE peptide receptor gene promoters are also provided, along with nematode CLE peptide receptor gene promoters that are useful for expressing genes in nematode feeding sites as well as transgenic plants and nematode resistant transgenic plants comprising the promoters. | 12-05-2013 |
20130312430 | GAS TANK REFUELING SYSTEM - A method of expansive-cooling an amount of a natural gas during transfer from a first storage container to a second storage container is provided. In addition, a system including two storage containers connected by an expander for the expansion of natural gas during the transfer from the first storage container to the second storage container is provided. | 11-28-2013 |
20130309274 | WOUND DEBRIDEMENT - A method for debridement of wound on the skin by placing against the wound a glass-based borate-based composition to release dissolution products which support neutrophilic activity into the wound by dissolution. | 11-21-2013 |
20130284956 | MICROFLUIDIC VALVE SYSTEMS AND METHODS - The present disclosure provides a mini-scale microfluidic valve including a valve housing disposed at a fluid dispensing orifice of a mini-scale microfluidic system dispensing nozzle. The valve housing comprises a base member having a base member orifice that aligns with the fluid dispensing orifice to provide a fluid dispensing pathway through which a system-fluid is dispensed from the system dispensing nozzle to an external ambient environment. The housing additionally comprises an open valve channel exposed to the external ambient environment and intersecting the fluid dispensing pathway. The valve further includes a liquid-film movably disposed within the open valve channel such that the liquid-film is exposed to the external ambient environment. The liquid-film comprises a substantially non-volatile, immiscible liquid, and a valve control subsystem structured and operable to control movement of the liquid-film within the open valve channel to selectively cover and uncover the base member orifice. | 10-31-2013 |
20130280781 | A CONTAMINANT REDUCING AMIDE FUNCTIONALIZED ORDERED MESOPOROUS CARBON CONJUGATE - The present invention provides a series of new and improved compounds/materials as vehicles to delivery degradative enzymes to remove/remedy environmental pollutants. The inventive material comprises a series of amide-functionalized ordered mesoporous carbon (AFOMC), which utilizes chemical conjugation techniques for the tethering of enzymes to the surface of the synthesized AFOMC. The delivery mechanism may be utilized to express a wide variety of toxin-degrading enzymes for removal/remediation of organic pollutants. | 10-24-2013 |
20130250244 | Device to Measure Pupillary Light Reflex In Infants and Toddlers - The present disclosure provides a pupillary light reflex (PLR) system, wherein the PLR system includes a remote tracking and imaging system that is structured and operable to generate and acquire high resolution pupil stimulus and response data from a test subject while the test subject is moving and is disposed a distance from remote tracking and imaging system that is greater than or equal to one-third of a meter. The PLR system additionally includes a computer based system controller that is structure and operable to execute PLR software to control the operation of the remote tracking and imaging system and compute PLR information based on the pupil stimulus and response data acquired as the test subject is moving. | 09-26-2013 |
20130244903 | MODULATORS OF ALPHA-SYNUCLEIN TOXICITY - Disclosed are compositions and methods for modulating expression of genes that function at the step of ER to Golgi trafficking. Compounds that modulate expression of these genes or activity of the encoded proteins can be used to inhibit alpha-synuclein mediated toxicity and used to treat or prevent synucleinopathies such as Parkinson's disease. Also disclosed are methods of identifying inhibitors of alpha-synuclein mediated toxicity. | 09-19-2013 |
20130229660 | Total Internal Reflection Photoacoustic Spectroscopy - A system and method of conducting total internal reflection photoacoustic spectroscopy (TIRPAS) comprising using a pulsed laser source to emit a thermally or stress confined laser beam at a prism comprising a surface to be in contact with a sample such that the laser beam travels through the prism to a location at an interface between the prism and the sample to form an evanescent field extending into the sample to generate a detectable photoacoustic response to the evanescent field by an analyte in the sample. | 09-05-2013 |
20130220809 | NANOPORE-FACILITATED SINGLE MOLECULE DETECTION OF NUCLEIC ACID - The present invention provides a new and improved oligonucleotide detection method based on the nanopore technology with a probe containing a complementary sequence to the target oligonucleotide and a terminal extension at the probe's 3′ terminus, 5′ terminus, or both termini. The improved nanopore sensor with the probe enables sensitive, selective, and direct detection, differentiation and quantification of target oligonucleotides such as miRNAs. The inventive detection method may also be employed as a non-invasive and cost-effective diagnostic method for cancer detection based on miRNA levels in the patient's blood sample. | 08-29-2013 |
20130211158 | HIGH SURFACE AREA CARBON AND PROCESS FOR ITS PRODUCTION - Activated carbon materials and methods of producing and using activated carbon materials are provided. In particular, biomass-derived activated carbon materials and processes of producing the activated carbon materials with prespecified surface areas and pore size distributions are provided. Activated carbon materials with preselected high specific surface areas, porosities, sub-nm (<1 nm) pore volumes, and supra-nm (1-5 nm) pore volumes may be achieved by controlling the degree of carbon consumption and metallic potassium intercalation into the carbon lattice during the activation process. | 08-15-2013 |
20130197375 | Hydraulic Bed Sensor and System for Non-Invasive Monitoring of Physiological Data - Disclosed herein is a new and improved non-invasive bed sensing system for detecting and monitoring physiological movements such as heartbeat and respiration. The system may employ a hydraulic fluid to transduce the physiological pressures to an integrated pressure sensor and a new and improved signal processing method to identify individual cardiac pulses from the electronic signals generated by the hydraulic transducer. The system provides increased sensitivity capable of capturing quantitative pulse and respiration rates with subtle changes, ability to distinguish between instances of low pulse rate and shallow breathing, and improved comfort over existing system. | 08-01-2013 |
20130190542 | HIGH SURFACE AREA CARBON AND PROCESS FOR ITS PRODUCTION - Activated carbon materials and methods of producing and using activated carbon materials are provided. In particular, biomass-derived activated carbon materials and processes of producing the activated carbon materials with prespecified surface areas and pore size distributions are provided. Activated carbon materials with preselected high specific surface areas, porosities, sub-nm (<1 nm) pore volumes, and supra-nm (1-5 nm) pore volumes may be achieved by controlling the degree of carbon consumption and metallic potassium intercalation into the carbon lattice during the activation process. | 07-25-2013 |
20130167262 | SOYBEAN VARIETY S05-11268 - A novel soybean variety designated S05-11268 is herein disclosed. This disclosure relates to the seeds of soybean variety S05-11268, to the plants of soybean S05-11268 to plant parts of soybean variety S05-11268 and to methods for producing a soybean plant produced by crossing plants of the soybean variety S05-11268 with another soybean plant, using S05-11268 as either the male or the female parent. | 06-27-2013 |
20130167261 | SOYBEAN VARIETY S05-11482 - A novel soybean variety designated S05-11482 is herein disclosed. This disclosure relates to the seeds of soybean variety S05-11482, to the plants of soybean S05-11482 to plant parts of soybean variety S05-11482 and to methods for producing a soybean plant produced by crossing plants of the soybean variety S05-11482 with another soybean plant, using S05-11482 as either the male or the female parent. | 06-27-2013 |
20130164732 | INORGANIC PYROPHOSPHATE AND USES THEREOF - The present invention provides a new and improved sperm stimulating additive comprising a certain amount of inorganic pyrophosphate (PPi). Addition of PPi in the media for human/animal in vitro fertilization (IVF) improves fertilization rate; addition of PPi in the semen extender for farm animal artificial insemination (AI) may improve pregnancy rates; furthermore, mammalian oocytes matured in vitro in a medium including PPi attain improved fertilization and developmental potential, while embryos cultured in medium supplemented with PPi have improved development to blastocyst. | 06-27-2013 |
20130158103 | Method of Tissue-Selective Targeted Gene Transfer - The present invention relates to methods of delivering a gene, such as a therapeutic gene, to a desired area of stroma of a cornea that involves removing the corneal epithelium and dehydrating the cornea. Certain aspects of the present invention relate to methods of treating corneal scarring by delivering a TGFβ-antagonizing gene packaged in a viral vector. | 06-20-2013 |
20130150251 | METHODS FOR ANALYZING LARIAT RNA - The present invention relates to compositions and methods useful for analyzing lariat RNA, which plays a role in the regulation of gene expression. A sample of RNA is specifically treated to remove linear mRNA and enrich for lariat RNA. The enriched lariat RNA sample may be analyzed further to identify introns, branch point sequences, alternative splicing patters, and gene transcription levels. The enriched lariat RNA sample may also be exploited as a detection or compound screening tool, as well as other uses. | 06-13-2013 |
20130144400 | SCAFFOLD FOR BONE AND TISSUE REPAIR IN MAMMALS - A mammalian tissue scaffold and method for making a tissue scaffold including a rigid scaffold body of biocompatible glass fibers bonded together and in special alignment to define open channels within the scaffold to allow fluid flow into and within the scaffold. | 06-06-2013 |
20130133871 | Multiple Thermal Circuit Heat Spreader - A heat spreader has more than one thermal circuit to give better performance over a wider range of heat input regimes. Different working fluids may be used in the different thermal circuits. The thermal circuits may extend in three dimensions to improve the density of the channels in limited space. | 05-30-2013 |
20130131302 | SOY-BASED POLYOLS - The invention provides processes for preparing soy-based oligomeric polyols or substituted oligomeric polyols, as well as urethane bioelasteromers comprising the oligomeric polyols or substituted oligomeric polyols. | 05-23-2013 |
20130129618 | EGCG STABILIZED GOLD NANOPARTICLES AND METHOD FOR MAKING SAME - The invention provides stabilized, biocompatible gold nanoparticles that are stabilized with material from epigallocatechin Gallate (EGCg), which is a polyphenols- or flavanoids-rich plant material that can be obtained from green tea. The EGCg is an an antioxidant reducing agent derived from green tea. The gold nanoparticles of the invention can be radioactive or non radioactive and are formed via a simple room temperature fabrication method. In preferred embodiment method of making, an aqueous solution containing gold salts is provided. The aqueous solution is mixed with EGCg in a buffer, such as deionized water. The gold salts react to form biocompatible gold nanoparticles that are stabilized with a coating of EGCg. The thermodynamically feasible redox couple of AuCl4-EGCg leading to the reduction of AuCl4- by EGCg to form gold nanoparticles. In another embodiment, pre-cooled gold salt and EGCg solutions form multi-layered EGCg coated particles. | 05-23-2013 |
20130115328 | MICROENCAPSULATED PROBIOTICS FOR REDUCING FECAL SHEDDING OF PATHOGENIC MICROBES IN ANIMALS - Disclosed are methods and compositions for reducing | 05-09-2013 |
20130108525 | METHOD FOR SEPARATION OF CHEMICALLY PURE OS FROM METAL MIXTURES | 05-02-2013 |
20130104909 | Surgical Drape | 05-02-2013 |
20130104262 | Drought Responsive Genes In Plants And Methods of Their Use - Microarrays are employed to analyze soybean transcriptions under water stress conditions in both root and leaf tissues at vegetative stage. Novel drought responsive genes may be thus identified and may be used for enhancing drought tolerance in soybean or other plants through genetic/metabolic engineering. This disclosure pertains to nucleic acid molecules isolated from Soybean that encode polypeptides that may be important for drought tolerance. The disclosure also relates to methods of using these genes from soybean in transgenic plants to confer the desired agronomic traits, and to use such genes or regulatory elements thereof to assist germplasm enhancement by molecular breeding or to identify other factors or chemicals that may enhance a plant's capability to grow under drought conditions. | 04-25-2013 |
20130084248 | STABILIZED, BIOCOMPATIBLE GOLD NANOPARTICLES - The invention provides stabilized, biocompatible gold nanoparticles that are stabilized with material from polyphenols- or flavanoids-rich plant material or reactive phytochemical components of the plant material. The gold nanoparticles of the invention can be fabricated with an environmentally friendly method for making biocompatible stabilized gold nanoparticles. In preferred embodiments, the coating consists of material from polyphenols- or flavanoids-rich plant material or reactive phytochemical components of the plant material. | 04-04-2013 |
20130078678 | Protozoan Glycosidases and Related Methods - Nucleic acids encoding glycosidases useful for the hydrolysis of cellulose and hemicellulose obtained from ciliates residing in a bovine rumen are provided. Also provided recombinant nucleic acids encoding the glycosidases, transformed cells comprising the same and related methods of using the transformed cells and glycosidases to degrade cellulose and/or hemicellulose. | 03-28-2013 |
20130078175 | HYDROXYLATION OF ICOSAHEDRAL BORON COMPOUNDS - The present invention relates to a synthetic method for producing a per-hydroxylated icosahedral boron compound via catalytic hydroxylation of icosahedral boron compound using a soft electrophile. | 03-28-2013 |
20130062314 | DIELECTRIC LOADED FLUIDS FOR HIGH VOLTAGE SWITCHING - This disclosure relates to methods and systems to reduce high voltage breakdown jitters in liquid dielectric switches. In particular, dielectric liquids have been produced that contain a suspension of nanoparticles and a surfactant to reduce the breakdown jitter. In one embodiment, the suspended nanoparticles are Barium Strontium Titanate (BST) nanoparticles. | 03-14-2013 |
20130057151 | SYSTEMS AND METHODS TO GENERATE A SELF-CONFINED HIGH DENSITY AIR PLASMA - This disclosure relates to methods and devices for generating electron dense air plasmas at atmospheric pressures. In particular, this disclosure relate to self-contained toroidal air plasmas. Methods and apparatuses have been developed for generating atmospheric toroidal air plasmas. The air plasmas are self-confining, can be projected, and do not require additional support equipment once formed. | 03-07-2013 |
20130054177 | Deep Level Transient Spectrometer - A method for detecting surface and bulk deep states in semiconductor materials is provided. In various embodiments, the method comprises configuring a detection circuit of charge based deep level transient spectrometer in one of a parallel mode and a series mode by controlling the configuration of a switching circuit of the detection circuit. The method additionally comprises generating digitized voltage charge outputs of a device under test utilizing the detection circuit as controlled via execution of an analog-to-digital conversion and timing program by a control system of the charge based deep level transient spectrometer. Furthermore, the method comprises obtaining desired information about deep level transients of the device under test based on the digitized voltage charge outputs via execution of a control system operable to execute a Q-DLTS data analysis program by the control system. | 02-28-2013 |
20130044776 | Integrated Advanced Heat Spreader for Solid-State Laser Systems - A thermal management apparatus and method for a solid-state laser system enabling the laser system to have near isothermal temperatures across and throughout a solid-state gain material, by mechanically controlling an oscillating heat pipe having effective thermal conductivity of 10-20,000 W/m*K; bonding a solid-state lasing crystal or ceramic to the mechanically controlled oscillating heat pipe; and providing a supporting structure including a surface bonded to the solid-state lasing crystal or ceramic that matches the coefficient of thermal expansion of both the solid-state lasing crystal or ceramic and the mechanically controlled oscillating heat pipe. | 02-21-2013 |
20130029008 | ENGINEERED COMESTIBLE MEAT - Provided are engineered meat products formed as a plurality of at least partially fused layers, wherein each layer comprises at least partially fused multicellular bodies comprising non-human myocytes and wherein the engineered meat is comestible. Also provided are multicellular bodies comprising a plurality of non-human myocytes that are adhered and/or cohered to one another; wherein the multicellular bodies are arranged adjacently on a nutrient-permeable support substrate and maintained in culture to allow the multicellular bodies to at least partially fuse to form a substantially planar layer for use in formation of engineered meat. Further described herein are methods of forming engineered meat utilizing said layers. | 01-31-2013 |
20130004417 | Gold Coated Lanthanide Nanoparticles - The present invention is directed α-particle emitting nanoparticles that comprise a lanthanide phosphate sequestration shell enclosing an α-emitting-radioisotope-doped lanthanide phosphate core such that the shell allows at least some of the α emissions from the α-emitting radioisotope to pass therethrough and prevents at least some radioactive decay products of the α-emitting radioisotope from exiting the α-particle emitting nanoparticle. Further, such α-particle emitting nanoparticles may be coated with gold and functionalized. Additionally, a method for making and using the same are disclosed. | 01-03-2013 |
20130000800 | HOMOGENEOUS MESOPOROUS NANOENERGETIC METAL OXIDE COMPOSITE FABRICATION METHODS - The invention provides methods for making homogeneous metal oxide nanoenergetic composites. A method of the invention forms a metal oxide nanostructure via a sol-gel process with surfactant templating. Metal nanoparticles are introduced into the metal oxide nanostructure via wet impregnation. | 01-03-2013 |
20120310673 | SYSTEM AND METHOD FOR LINKING A WEB-BASED RESOURCE WITH AN ELECTRONIC MEDICAL RECORD - A data processing system and method that, in some cases, include an EMR system and a web server. In some cases, the EMR system includes a plurality of electronic medical records for a plurality of patients. One or more of the electronic medical records may include a URL or HTTP Post message that defines a path to a web-based resource, such as a treatment algorithm or medical calculator. In some embodiments, the URL and/or HTTP Post message is constructed based on information in a patient's medical record. | 12-06-2012 |
20120309268 | METHOD AND APPARATUS FOR JET-ASSISTED DRILLING OR CUTTING - An abrasive cutting or drilling system, apparatus and method, which includes an upstream supercritical fluid and/or liquid carrier fluid, abrasive particles, a nozzle and a gaseous or low-density supercritical fluid exhaust abrasive stream. The nozzle includes a throat section and, optionally, a converging inlet section, a divergent discharge section, and a feed section. | 12-06-2012 |
20120289550 | COMPOSITION COMPRISING A COMBINATION OF OMEPRAZOLE AND LANSOPRAZOLE, AND A BUFFERING AGENT, AND METHODS OF USING SAME - The present disclosure relates to pharmaceutical compositions comprising omeprazole, lansoprazole and sodium bicarbonate. Methods of using such compositions are also provided | 11-15-2012 |
20120288938 | SELF-ASSEMBLING CELL AGGREGATES AND METHODS OF MAKING ENGINEERED TISSUE USING THE SAME - A composition comprising a plurality of cell aggregates for use in producing engineered organotypic tissue by organ printing. A method of making a plurality of cell aggregates comprises centrifuging a cell suspension, extruding the resulting pellet through an orifice, and cutting the extruded pellet into pieces. Apparatus for making cell aggregates comprises an extrusion system and a cutting system. In a method of organ printing, a plurality of cell aggregates are embedded in a polymeric or gel matrix and allowed to fuse to form a desired three-dimensional tissue structure. An intermediate product comprises at least one layer of matrix and a plurality of cell aggregates embedded therein in a predetermined pattern. Modeling methods predict the structural evolution of fusing cell aggregates for combinations of cell type, matrix, and embedding patterns to enable selection of organ printing process parameters for use in producing an engineered tissue having a desired three-dimensional structure. | 11-15-2012 |
20120276218 | CONTROLLING CALCIUM COMPOUND FORMATION IN BIOCOMPATIBLE MATERIALS FOR TISSUE REGENERATION AND REPAIR IN MAMMALS - A biocompatible composition for tissue repair or regeneration in mammals comprising one or more glass former compounds selected from the group consisting of B | 11-01-2012 |
20120250962 | METHOD OF PREDICTING CROP YIELD LOSS DUE TO N-DEFICIENCY - A method for determining the yield loss of a crop using remote sensor data is described. The yield loss is determined using the reflectivity of green light by the crop canopy measured from remote sensor data such as an aerial photograph that is digitized and spatially referenced to the field's longitude and latitude. Green pixel values from the aerial photograph, expressed relative to green pixel values from well-fertilized areas of the field, are transformed to yield losses using a linear transformation that was developed using empirical data. A similar method is described to determine recommended nitrogen fertilization rates for the crop fields. The yield loss data is useful for nitrogen fertilization management, as it allows a producer of crops to weigh the expense of fertilization against the loss of revenue due to yield loss. | 10-04-2012 |
20120245016 | HIGH DIELECTRIC CONSTANT COMPOSITE MATERIALS AND METHODS OF MANUFACTURE - The present invention relates to composite materials with a high dielectric constant and high dielectric strength and to methods of producing the composite materials. The composite materials have high dielectric constants at a range of high frequencies and possess robust mechanical properties and strengths, such that they may be machined to a variety of configurations. The composite materials also have high dielectric strengths for operation in high power and high energy density systems. In one embodiment, the composite material is composed of a trimodal distribution of ceramic particles, including barium titanate, barium strontium titanate (BST), or combinations thereof and a polymer binder. | 09-27-2012 |
20120237677 | PATTERNING OF ULTRA-LOW REFRACTIVE INDEX HIGH SURFACE AREA NANOPARTICULATE FILMS - A method for forming a nanoporous film pattern on a substrate comprising imparting differential surface energy to a surface of a substrate to define first areas having a first surface energy conducive to maintenance of a nanoporous film thereon and second areas having a second surface energy non-conducive to maintenance of a nanoporous film thereon, said first and second areas defining a differential surface energy pattern on the substrate; depositing a nanoporous film precursor onto the differential surface energy pattern; and curing the nanoporous film precursor to form the nanoporous film pattern. | 09-20-2012 |
20120235696 | HIGH FREQUENCY ANALYSIS OF A DEVICE UNDER TEST - Analyzing a device under test (“DUT”) at higher frequencies. A phase shifter varies the phase of a standing wave on a transmission line coupled to the DUT. The standing wave magnitude is sampled at each of the phase shifts and one or more DUT characteristics are determined as a function of the sampled magnitudes and phase shifts. Further aspects include a related phase shifter comprising a waveguide having a plurality of sub-resonant slots formed therein and having active elements for loading the slots to control the phase shift applied to the signal. | 09-20-2012 |
20120226261 | Intramammary Injection Device - In various embodiments, the present disclosure provides an injection system for injecting a fluidic treatment substance into an orifice of an animal. In various implementations the system comprises a treatment cartridge having a hollow body that is structured and operable to retain a treatment substance within the hollow body. The system further comprises a plunger assembly structured and operable to removably retain the treatment cartridge and controllably dispense the treatment substance from the treatment cartridge. In various implementations the injection system can additionally include an injection site cleaning adaptor that is removably connectable to the treatment cartridge and is structured and operable to clean a site in which the treatment substance is to be injected. | 09-06-2012 |
20120221573 | Methods and systems for biclustering algorithm - Methods and systems for improved unsupervised learning are described. The unsupervised learning can consist of biclustering a data set, e.g., by biclustering subsets of the entire data set. In an example, the biclustering does not include feeding know and proven results into the biclustering methodology or system. A hierarchical approach can be used that feeds proven clusters back into the biclustering methodology or system as the input. Data that does not cluster may be discarded. Thus, a very large unknown data set can be acted on to learn about the data. The system is also amenable to parallelization. | 08-30-2012 |
20120221059 | CERVICAL SPINE CLAMP - A spine immobilization system is provided wherein the system includes a plurality of vertebra clamps structured and operable to be clamped to one of a plurality of target vertebrae, a pair of retaining rails disposable along the length of the target vertebrae between the clamps and each of the target vertebrae, and a pair of clamp interlocking rods structured and operable to interlock the clamps together once each clamp is clamped to the respective one of the target vertebra such that the target vertebrae are securely held together to provide a cumulative, unified vertebral body, whereby the target vertebrae can only move simultaneously together as a single cumulative, unified structure. | 08-30-2012 |
20120220911 | WOUND CARE - A method for treating a wound, and a dressing for wound care management comprising a three-dimensional body of glass-based fibers comprising one or more glass-formers selected from the group consisting of P | 08-30-2012 |
20120205011 | Protective Conversion Coating on Mixed-Metal Subtrates and Methods Thereof - Mixed-metal automotive vehicle bodies-in-white comprising ferrous metal surfaces, zinc surfaces, aluminum alloy surfaces, and magnesium alloy surfaces are cleaned and immersed in an aqueous bath comprising an adhesion promoter and an aqueous electrocoat bath (the adhesion promoter may be in the electrocoat bath. The adhesion promoter, which may be a cerium salt, is selected to react with each metal in the body surfaces to form an oxide layer that provides corrosion resistance for the surface and adherence for the deposited polymeric paint coating. The body is cathodic in the electrocoat deposition. | 08-16-2012 |
20120196343 | SELF-ASSEMBLING MULTICELLULAR BODIES AND METHODS OF PRODUCING A THREE-DIMENSIONAL BIOLOGICAL STRUCTURE USING THE SAME - Structures and methods for tissue engineering include a multicellular body including a plurality of living cells. A plurality of multicellular bodies can be arranged in a pattern and allowed to fuse to form an engineered tissue. The arrangement can include filler bodies including a biocompatible material that resists migration and ingrowth of cells from the multicellular bodies and that is resistant to adherence of cells to it. Three-dimensional constructs can be assembled by printing or otherwise stacking the multicellular bodies and filler bodies such that there is direct contact between adjoining multicellular bodies, suitably along a contact area that has a substantial length. The direct contact between the multicellular bodies promotes efficient and reliable fusion. The increased contact area between adjoining multicellular bodies also promotes efficient and reliable fusion. Methods of producing multicellular bodies having characteristics that facilitate assembly of the three-dimensional constructs are also provided. | 08-02-2012 |
20120190583 | Combination of Single-Cell Electroporation and Electrical Recording Using the Same Electrode - Methods for stimulating exocytosis from a cell are provided where the same electrochemical microelectrode is used to electroporate an adjacent cell and then measure quantal exocytosis from the adjacent cell. Also provided are methods for stimulating and measuring exocytosis from a select cell population arrayed on a chip comprising addressable electrodes. Calcium independent stimulation of exocytosis with inorganic anions such as chloride ions is also provided. These methods can provide for specific stimulation of a desired subset of cells without exposing other nearby cells to the stimulus. | 07-26-2012 |
20120178130 | REUSABLE PCR AMPLIFICATION SYSTEM AND METHOD - A DNA amplification device utilizing a polydimethylsiloxane (PDMS) and silicon substrate coated with spin-on glass (SOG) is provided. This PDMS layer is irreversibly bonded to the SOG layer of the silicon substrate using oxygen plasma. The amplification device is an inexpensive, microfluidic device, which can be utilized as a portable thermo-cycler to perform PCR amplification of DNA in the field. | 07-12-2012 |
20120148004 | Apparatus and Method for Directional and Spectral Analysis of Neutrons - A neutron detection system may include a volume of neutron moderating material, and a plurality of solid state neutron detection devices disposed within the volume of neutron moderating material, wherein some of the neutron detection devices suitable for transduction of primary reaction products resulting from a neutron interaction event, wherein some of the solid state neutron detection devices include two or more solid state neutron detection elements, and wherein the solid state neutron detection elements are configured for omnidirectional detection of impinging neutrons. | 06-14-2012 |
20120134918 | GUM ARABIC COATED 198GOLD RADIOACTIVE NANOPARTICLES FOR CANCER THERAPY - The invention provides a cancer therapeutic and imaging agent comprising a solution containing Gum Arabic coated | 05-31-2012 |
20120130421 | RATCHETING STAPLE FOR SURGICAL APPLICATIONS - A surgical staple device which accommodates various tissue thicknesses by employing unique modified surfaces with increased friction is disclosed. The staple device includes a U-shaped staple body with modified surfaces on its legs, whereas the modified surfaces may be designed as ratchet teeth, barbs, hooks, grooves, and channels. The staple device further includes a footplate to receive and engage the legs. | 05-24-2012 |
20120129970 | POLYMER COMPOSITES AND FABRICATIONS THEREOF - The present invention provides polymer composites reinforced with high aspect ratio reinforcing fillers selected from calcium phosphate nanofibers, nanoplates, submicron fibers, submicron plates, and combinations thereof. The mechanical and biological properties of the inventive composites are enhanced significantly over current polymer composites and may be employed in various biomedical applications, such as dental restorations. | 05-24-2012 |
20120094828 | HIGH SURFACE AREA CARBON AND PROCESS FOR ITS PRODUCTION - The present invention provides a high surface area porous carbon material and a process for making this material. In particular, the carbon material is derived from biomass and has large mesopore and micropore surfaces that promote improved adsorption of materials and gas storage capabilities. | 04-19-2012 |
20120093994 | Meat Analog Compositions and Process - Analog meat compositions produced from vegetable protein and processes for producing the analog meat compositions are described. The compositions are produced with high moisture content, low vegetable protein content, carbohydrate, and, optionally, an edible lipid material and provides a product that simulates the fibrous structure of animal meat and has a desirable meat-like moisture, texture, mouthfeel, flavor and color. | 04-19-2012 |
20120083907 | VARIABLE PRODUCT AGROCHEMICALS APPLICATION MANAGEMENT - Methods and products are provided for facilitating application of variable-product agrochemicals, such as fertilizer, to an application area, such as a field. The fertilizer or agrochemical may include a single fertilizer or agrochemical type or a mixture. In one embodiment, a fertilizer-application area is divided into application cells, and a fertilizer product is determined for each cell, based on zones of the application area with a similar characteristic, such as topographic wetness index levels. Based on a determined product for each cell, instructions for controlling an agrochemical applicator are automatically generated. | 04-05-2012 |
20120071682 | ORGANOSILICA NANOPARTICLES AND METHOD FOR MAKING - Preparation of Free-Flowing Organosilica Nanoparticles by Forming a solution of an organosilica nanoparticle precursor in a mixed solvent system comprising a first solvent and a second solvent, wherein the first solvent is different from the second solvent, wherein the second solvent has a boiling point which is greater than a boiling point of the first solvent, and wherein the nanoparticle precursor has a greater solubility in the first solvent than in the second solvent; removing at least 50% of the first solvent to form nanoparticles having a mean particle size less than about 25 nanometers dispersed in the solution; adding a coupling agent to the solution to facilitate reacting of the coupling agent with the nanoparticles; and recovering the nanoparticles from the solution, wherein the recovered nanoparticles have the mean particle size of less than about 25 nanometers | 03-22-2012 |
20120064566 | MULTIPLE PHASE FLOW SYSTEM FOR DETECTING AND ISOLATING SUBSTANCES - A multiple flow system and method for detecting substances in a fluid is provided. More specifically, a first fluid tube containing a first fluid and a second fluid tube containing a second fluid are coupled to a common fluid tube via a connector, such that alternating discrete compartments of the first fluid and the second fluid flow through the common fluid tube. The first and second fluids are immiscible. A substance detector, having a flow chamber with an internal wall, is coupled to the common fluid tube. The alternating discrete compartments of the first and second fluids flow through the flow chamber and are analyzed by the substance detector. | 03-15-2012 |
20120047588 | Methods for Conditional and Inducible Transgene Expression to Direct the Development of Embryonic, Embryonic Stem, Precursor and Induced Pluripotent Stem Cells - Methods are disclosed in which the expression of a specific gene, or combinations of genes, is controlled spatially and temporally to develop intra- and interspecies chimeras. A transgenic EC/ES/P/iPS cell line is created which conditionally expresses a suicide or compromiser gene configured to compromise all cell lineages except that corresponding to a target tissue/organ. The EC/ES/P/iPS cell line is injected into donor embryos having a specific target gene deficiency or embryos genetically engineered to be complementary compromised in lineages corresponding to the target tissue/organ cell lineages of the EC/ES/P/iPS line. One or more stimuli is provided to the embryo to activate compromiser genes for ablation of non-target tissues/organs of the EC/ES/P/iPS line and target tissues/organs of the host embryo, resulting in a chimeric animal having target tissues/organs derived from the genotype of the transgenic cell line and all remaining tissues/organs derived from the donor embryo. | 02-23-2012 |
20120015874 | NOVEL INHIBITORS OF RETROVIRAL REVERSE TRANSCRIPTACE - Disclosed are nucleic acid molecules, and methods of their use, which have a specific structure including a double helical domain and a G-quadruplex domain physically connected by a linker domain which may be nucleosidic or non-nucleosidic. These aptamers demonstrate potent inhibition of phylogenetically diverse primate lentiviral reverse transcriptases, which effect is largely independent of aptamer sequence provided that the aptamer has the specified structure. | 01-19-2012 |
20110313542 | ENGINEERED BIOLOGICAL NERVE GRAFT, FABRICATION AND APPLICATION THEREOF - An engineered three-dimensional structure includes living cells cohered with each other. The living cells suitably include Schwann cells and at least one other type of cell. The cells accompanying the Schwann cells can suitably be bone marrow stem cells or another type of cell having one or more anti-inflammatory properties. The structure is suitably a graft that facilitates restorative axon growth when the graft is implanted between the proximal and distal stubs of a severed nerve in a living organism. The graft can optionally include a plurality of acellular conduits extending between opposite axial ends of the graft. Bio-printing techniques can be used to assemble a three-dimensional construct that becomes through maturation an axon-guiding graft, by stacking a plurality of multicellular bodies, each of which includes a plurality of living cells cohered to one another to sufficiently to avoid collapsing when the multicellular bodies are stacked to form the structure. | 12-22-2011 |
20110313392 | STEERABLE EPIDURAL CATHETER - A steerable catheter device which can be steered to locations within the epidural space, as well as methods of use and manufacture are disclosed. The steerable catheter provides a site-specific drug delivery system for accessing the epidural space. The catheter devices includes a steerable wire or a liner extending from a proximal end of the catheter to the catheter's distal end. Forces applied to the wire or the liner cause the distal end to deflect and/or rotate to reach a targeted epidural site. | 12-22-2011 |
20110293840 | SYSTEMS AND METHODS FOR FABRICATING A DIRECT METAL DEPOSITION STRUCTURE HAVING FULLY FORGED STRUCTURAL QUALITIES - A method for fabricating a direct metal deposition (DMD) structure having substantially fully forged structural qualities is provided. In various embodiments, the method includes depositing a layer of metallic material onto an existing metallic structure having a microstructure that provides the existing metallic structure with substantially fully forged structural qualities. The DMD layer has a microstructure that provides the DMD layer with non-forged structural qualities. The method additionally includes applying a friction stir process to the deposited DMD layer utilizing a friction stir device such that the deposited DMD layer and at least a DMD affected zone of the existing metallic structure are friction stirred to refine and homogenize the microstructure of the deposited DMD layer and at least the DMD affected zone of the existing metallic structure, thereby producing a non-forged aggregate structure having a microstructure that provides the aggregate structure substantially fully forged structural qualities. | 12-01-2011 |
20110290252 | CLOSED LOOP RESPIRATORY SUPPORT DEVICE WITH DYNAMIC ADAPTABILITY - The invention provides an automatic system based on the dynamic adaptability strategy for controlling oxygen concentration in blood of patients with fluctuating oxygen needs. The inventive system monitors patient's clinical measurement data and updates the system continuously, which provides changes in FiO | 12-01-2011 |
20110281316 | BACILLUS BASED DELIVERY SYSTEM AND METHODS OF USE | 11-17-2011 |
20110277592 | SEPARATION METHOD FOR CARRIER-FREE RADIOLANTHANIDES - A method for separating a lanthanide from a mixture containing at least one other lanthanide is provided. In particular, an HPLC and liquid separation method using a chromatographic column for separating a lanthanide from a mixture containing at least one other lanthanide is provided. | 11-17-2011 |
20110259039 | Thermally Driven Heat Pump for Heating and Cooling - A thermally driven heat pump includes a low temperature evaporator for evaporating cooling fluid to remove heat A first heat exchanger located at an outlet of a converging/diverging chamber of a first ejector receives a flow of primary fluid vapor and cooling fluid vapor ejected from the first ejector for condensing a portion of the cooling fluid vapor An absorber located in the first heat exchanger absorbs cooling fluid vapor into an absorbing fluid to reduce the pressure in the first heat exchanger A second heat exchanger located at an outlet of a converging/diverging chamber of a second ejector receives primary fluid vapor and cooling fluid vapor ejected from the second ejector for condensing the cooling fluid vapor and the primary fluid vapor A separator in communication with the second ejector, the low temperature evaporator and the primary fluid evaporator separates the primary fluid from the cooling fluid. | 10-27-2011 |
20110250667 | FOSSIL FUEL-FREE PROCESS OF LIGNOCELLULOSIC PRETREATMENT WITH BIOLOGICAL HYDROGEN PRODUCTION - The invention provides an isolated haloalkaliphilic microorganism designated as strain sapolanicus belonging to the genus | 10-13-2011 |
20110237057 | SYSTEMS AND METHODS FOR CO-DOPING WIDE BAND GAP MATERIALS - Various embodiments of the present disclosure provide a method of simultaneously co-doping a wide band gap material with p-type and n-type impurities to create a p-n junction within the resulting wide band gap composite material. The method includes disposing a sample comprising a dopant including both p-type and n-type impurities between a pair of wide band gap material films and disposing the sample between a pair of opposing electrodes; and subjecting the sample to a preselected vacuum; and heating the sample to a preselected temperature; and applying a preselected voltage across the sample; and subjecting the sample to at least one laser beam having a preselected intensity and a preselected wavelength, such that the p-type and n-type impurities of the dopant substantially simultaneously diffuse into the wide band gap material films resulting in a wide band gap compound material comprising a p-n junction. | 09-29-2011 |
20110224673 | JOINT IMPLANT AND PROSTHESIS AND METHOD - Disclosed herein is a minimally invasive ball joint implant and prosthesis for the treatment of arthritis, trauma, and other medical conditions leading to joint destruction and pain, as well as methods of use. In various cases, the prosthesis does not require reaming into the intramedullary canal and does not require diaphyseal fit for any bones associated with the joint, thereby resulting in more rapid and complete recovery. In various cases, the prosthesis incorporates an anchoring stem specifically designed to be impacted into the bone and to facilitate bony ingrowth after implantation, thereby strengthening the implanted prosthesis and preventing rotation thereof. | 09-15-2011 |
20110223616 | HuR-Associated Biomarkers - The present invention relates to methods of identifying gene targets, including methods of using ribonucleoprotein (RNP) immunoprecipitation-microarrays to identify cancer gene targets, such as subsets of RNP-associated mRNAs in breast cancer cell lines. Also presented, are ribonucleotide binding protein-associated biomarkers, panels or sets of ribonucleotide binding protein-associated biomarkers, methods and compositions comprising ribonucleotide-binding protein, associated nucleotides, nucleotide arrays, and kits to facilitate the diagnosis of and monitoring the disease status or progression of treatment of breast cancers, including drug-resistant breast cancers. | 09-15-2011 |
20110218116 | BIOMARKERS OF OSTEOARTHRITIS - Biomarkers, biomarker panels and methods for diagnosing osteoarthritis (OA) are disclosed, using measurement of the expression level of certain polypeptides in a test sample from a subject, including MCP1, IL8, KC, MMP2, MMP3, IL6, MMP1, RANTES, MMP9, IL1B, Apolipoprotein A1, Apolipoprotein E, DCN, CILP and COMP. Related methods for monitoring OA treatment efficacy, diagnostic reagents, and kits are also described. | 09-08-2011 |
20110217762 | PHOTO-ACOUSTIC DETECTION DEVICE AND METHOD - An example method for detecting an analyte in a sample of a bodily fluid comprises the steps of exposing the bodily fluid sample to electromagnetic energy to cause a thermoelastic expansion in the analyte, and detecting a photoacoustic signal in the sample that results from the thermoelastic expansion. | 09-08-2011 |
20110213198 | HIGH-THROUGHPUT AND NON-INVASIVE METHOD TO VITRIFY PORCINE EMBRYOS - The present invention provides a practical, non-invasive, and efficient method for cryopreservation of an in-vitro-produced porcine embryo. The inventive method treats the NP (such as IVF- or NT-derived) embryo at the one-cell or cleavage stage prior to compaction with high osmolality followed by high speed centrifugation. The high osmolality treatment enlarges the periviteline space, and with centrifugation, enables the separation of the lipids from the cytoplasm. The lipid-separated embryos after high osmolality treatment have been successfully cryopreserved and later recovered and transferred to produce live offspring. | 09-01-2011 |
20110206077 | Thin Disk Laser Operations with Unique Thermal Management - A thermal management apparatus and method for a thin disk laser system enabling the laser system to have near isothermal temperatures across and throughout a thin disk comprising a mechanically controlled oscillating heat pipe having effective thermal conductivity of 10-20,000 W/m*K that promotes near isothermal conditions in lasing of the thin disk, a thin disk lasing crystal or ceramic bonded to the mechanically controlled oscillating heat pipe, and a supporting structure including a surface bonded to the thin disk that matches the CTE (coefficient of thermal expansion) of both materials. | 08-25-2011 |
20110204122 | HOLLOW STRUCTURES FORMED WITH FRICTION STIR WELDING - A hollow structure, and a method of forming the hollow structure, where the hollow structure includes first and second metal parts, the second metal part having an interior surface and a tapered support member extending from the interior surface. The hollow structure also includes a friction stir welded joint that extends through the first metal part and into the tapered support member. | 08-25-2011 |
20110199015 | DIAMOND COMPOSITE AS ILLUMINATION SOURCE - The present disclosure provides a new diamond composite comprising a diamond material doped with a preselected transition metal or metal compounds as an illumination source with broadband white light luminosity, high efficiency, and enhanced life span. The present disclosure also provides a new method of diffusing dopants (such as transition metal or metal compounds) into an intended material (such as a diamond material). | 08-18-2011 |
20110196382 | DEVICE TO ASSIST DELIVERY OF FETAL HEAD AT CESAREAN SECTION - In various cases, an obstetrical device is provided for assisting a cesarean section delivery of a neonate having a fetal presenting part well seated within the mother's pelvis. Generally, the device comprises a tubular tail having an internal lumen and a hollow head extending from a distal end of the tail and having an internal chamber fluidly connected to the lumen. The head includes at least one aperture extending through an exterior wall. The device is operable to position the head near or in contact with the fetal presenting part to provide air into an area near and/or between contact surfaces of the fetal presenting part and a vagina and/or a cervix of the mother. Providing the air will reduce or release a suction formed between the contact surfaces such that the well seated fetal presenting part can be easily separated from the vagina and/or the cervix. | 08-11-2011 |
20110165221 | WOUND CARE - A method for treating a wound, and a dressing for wound care management comprising a three-dimensional body of glass-based fibers comprising one or more glass-formers selected from the group consisting of P | 07-07-2011 |
20110165217 | SCAFFOLDS WITH TRACE ELEMENT FOR TISSUE REGENERATION IN MAMMALS - A scaffold for implantation into a mammal to facilitate vessel growth in repair, regeneration, and/or proliferation of bodily tissue, where the scaffold is based on a borate, silicate, or phosphate, glass-former and is biodegradable upon implantation in mammals. The scaffold includes one or more trace elements from the group consisting of Cu, F, Fe, Mn, Mo, Ni, Sr, and Zn which are released into the host to support vessel growth. A method involves implantation of such scaffolds. | 07-07-2011 |
20110147217 | METHOD AND APPARATUS FOR CANCER SCREENING - A method and apparatus for detection of pteridine levels in a biological sample using CE-LIF which is useful for early cancer screening involving fully oxidizing pteridine compounds in a sample such as a urine sample, subjecting to CE-LIF to assess compound concentration, and compare to expected levels in for healthy or cancer-bearing patients. | 06-23-2011 |
20110110896 | Modulating levels of RNA-binding proteins for the treatment of breast cancer - The present invention relates to methods of using RNA-binding protein modulating agents to treat of cancer, particularly patients that are susceptible to or diagnosed with estrogen receptor-negative breast cancer, such as methods of inhibiting the growth or metastasis of cancer cells comprising contacting cells with a therapeutically-effective amount of an HuR-modulating agent. The invention also relates to compositions comprising therapeutically-effective amounts of an HuR-modulating agent. | 05-12-2011 |
20110083493 | Liquid Chromatography Detector and Flow Controller Therefor - A flow controller for use with a liquid chromatography detector. The flow controller includes a flow channel comprising an inlet portion, a control channel portion in communication with the inlet portion, and an outlet portion in communication with said control channel portion. The control channel portion has a cross-sectional area smaller than a cross-sectional area of a drift tube of the liquid chromatography detector for channeling the flow of droplets through the smaller cross-sectional area. The flow controller is shaped and sized to reduce pressure fluctuations and turbulence in the droplet stream of the liquid chromatography detector. | 04-14-2011 |
20110081676 | RAPID DETECTION OF VIABLE BACTERIA SYSTEM AND METHOD - An improved system and method is provided for detecting viable bacteria in a suspension sample. A sample of a suspension in which bacterial presence is suspected is collected from a source and a portion of the sample transferred to a microfluidic unit. A series of analysis signals at different frequencies are applied to the sample portion. An impedance is measured via a signal analyzer for the sample portion for each of the analysis signals to define an impedance data set. An initial bulk capacitance value is determined for a model circuit based on the impedance dataset. After a predetermined time period, a new bulk capacitance value is determined for on another portion of the sample. The difference between the new bulk capacitance and the initial bulk capacitance value is compared to a threshold value to determine if viable bacterial is present in the sample. | 04-07-2011 |
20110079719 | EXTERNAL/INTERNAL OPTICAL ADAPTER WITH BIASED PHOTODIODES FOR FTIR SPECTROPHOTOMETER - A Fourier Transfer Infrared (FTIR) spectrophotometer having reduced baseline noise. The system and method include internal or external optical adapters having a moveable beamsplitter for splitting the source light beam into a reference beam and a sample beam, and may include a variable bandpass filter, variable preamplifier and reversed biased photodiodes. | 04-07-2011 |
20110079718 | EXTERNAL/INTERNAL OPTICAL ADAPTER FOR FTIR SPECTROPHOTOMETER - A Fourier Transfer Infrared (FTIR) spectrophotometer having reduced baseline noise. The system and method include internal or external optical adapters having a moveable beamsplitter for splitting the source light beam into a reference beam and a sample beam, and may include a variable bandpass filter, variable preamplifier and reversed biased photodiodes. | 04-07-2011 |
20110076705 | COMPOSITIONS AND METHODS FOR EARLY PREGNANCY DIAGNOSIS - Disclosed are antibodies and methods for detecting pregnancy in an animal. In certain aspects antibodies used binds immunologically to at least two PAGs selected from PAG4, PAG6, PAG9, PAG16, PAG17, PAG19, PAG20 and PAG21. Antibody encoding nucleic acids are also provided, as are kits, methods of use and additional antibody related compositions. | 03-31-2011 |
20110070451 | TRANSPARENT COMPOSITES AND LAMINATES AND METHODS FOR MAKING - An exemplary method for making a transparent composite includes steps of combining a refractive index modifier with a precursor solution to provide a modified polymer precursor solution, combining glass with the modified precursor solution, and curing the modified precursor solution to create a transparent glass reinforced polymer composite. An example refractive index modifier comprises a monofunctional compound or monofunctional monomer, a polyfunctional compound or polyfunctional monomer or polymer, which is combined with the polymer precursor solution to increase the crosslinking density of the chain in the cured modified polymer precursor solution, and thus increase the refractive index. An exemplary transparent composite comprises a glass reinforced thermosetting polymer composite layer sandwiched between glass layers. | 03-24-2011 |
20110014262 | CONTROLLING VESSEL GROWTH AND DIRECTIONALITY IN MAMMALS AND IMPLANTABLE MATERIAL - A method for directing vessel growth toward a blood-deficient site in a mammal comprising implanting into the mammal an assembly of at glass fibers to form a vascular bridge with a first end of the vascular bridge in contact with the blood-deficient site and a second end of the vascular bridge remote from the blood-deficient site. Over time the bridge biodegrades and promotes vascularity in the direction of the bridge. | 01-20-2011 |
20110014261 | SCAFFOLD FOR TISSUE REGENERATION IN MAMMALS - A three-dimensional scaffold with interconnected pores for repair of tissue comprising a scaffold body for structural support of the tissue scaffold, where the scaffold body comprises scaffold body components bonded to each other and made from component materials comprising about 40 to about 90 wt % B | 01-20-2011 |
20110005305 | LIQUID CHROMATOGRAPHY DETECTOR AND FLOW CONTROLLER THEREFOR - A flow controller for use with a liquid chromatography detector. The flow controller includes a flow channel comprising an inlet portion, a control channel portion in communication with the inlet portion, and an outlet portion in communication with said control channel portion. The control channel portion has a cross-sectional area smaller than a cross-sectional area of a drift tube of the liquid chromatography detector for channeling the flow of droplets through the smaller cross-sectional area. The flow controller is shaped and sized to reduce pressure fluctuations and turbulence in the droplet stream of the liquid chromatography detector. | 01-13-2011 |
20100331879 | Articulating Surgical Hand Tool - A surgical instrument comprising a frame, a control-effector coupled to the frame, a shaft, and an end effector in fluid communication with the control-effector is disclosed. | 12-30-2010 |
20100328436 | ANONYMIZED VIDEO ANALYSIS METHODS AND SYSTEMS - Methods and systems for anonymized video analysis are described. In one embodiment, a first silhouette image of a person in a living unit may be accessed. The first silhouette image may be based on a first video signal recorded by a first video camera. A second silhouette image of the person in the living unit may be accessed. The second silhouette image may be of a different view of the person than the first silhouette image. The second silhouette image may be based on a second video signal recorded by a second video camera. A three-dimensional model of the person in voxel space may be generated based on the first silhouette image, the second silhouette image, and viewing conditions of the first video camera and the second video camera. In some embodiments, information on falls, gait parameters, and other movements of the person living unit are determined. Additional methods and systems are disclosed. | 12-30-2010 |
20100328142 | MICROWAVE AND MILLIMETER WAVE RESONANT SENSOR HAVING PERPENDICULAR FEED, AND IMAGING SYSTEM - A switched-slot sensor for use in a sensor array for microwave and/or millimeter wave imaging. The locations of a plurality of sensors in the array define a spatial domain away from an object for detecting an electric field from the object. Each of the sensors has an out-of-plane transmission line and outputs a signal representative of the measured field and the location of the sensor. A processor decodes the signals and generates an image of the object. | 12-30-2010 |
20100302043 | INTEGRATED SENSOR NETWORK METHODS AND SYSTEMS - Methods and systems for an integrated sensor network are described. In one embodiment, sensor data may be accessed from a plurality of motion sensors and a bed sensor deployed in a living unit for a first time period. An activity pattern for the first time period may be identified based on at least a portion of sensor data associated with the first time period. The activity pattern may represent a physical and cognitive health condition of a person residing in the living unit. Additional sensor data may be accessed from the motion sensors and the bed sensor deployed for a second time period. A determination of whether a deviation of the activity pattern of the first time period has occurred for the second time period may be performed. An alert may be generated based on a determination that the derivation has occurred. In some embodiments, user feedback is captured on the significance of the alerts, and the alert method is customized based on this feedback. Additional methods and systems are disclosed. | 12-02-2010 |
20100288026 | LIQUID CHROMATOGRAPHY DETECTOR AND FLOW CONTROLLER THEREFOR - A flow controller for use with a liquid chromatography detector. The flow controller includes a flow channel comprising an inlet portion, a control channel portion in communication with the inlet portion, and an outlet portion in communication with said control channel portion. The control channel portion has a cross-sectional area smaller than a cross-sectional area of a drift tube of the liquid chromatography detector for channeling the flow of droplets through the smaller cross-sectional area. The flow controller is shaped and sized to reduce pressure fluctuations and turbulence in the droplet stream of the liquid chromatography detector | 11-18-2010 |
20100285518 | PHOTOACOUSTIC DETECTION OF ANALYTES IN SOLID TISSUE AND DETECTION SYSTEM - A preferred system for detecting an analyte in solid tissue, such as an intact lymph node, in vitro includes a laser arranged to generate a pulsed laser beam into solid tissue, which can be a fully intact lymph node. An acoustic sensor, and preferably at least three acoustic sensors are arranged in different positions to span a three dimensional space, such as in an X, Y and Z coordinate system, to detect photoacoustic signals generated within the lymph node. At least one computer receives signals from the acoustic sensor(s). The computer determines the presence or absence of, and preferably the position of analyte, from the signals and the timing of the signals. A preferred method for detecting an analyte in a lymph node in vitro includes exposing an extracted lymph node to a pulsed laser beam. A photoacoustic signal is sensed. The photoacoustic signal is analyzed to confirm the presence or absence of an analyte in the lymph node. Preferably, multiple photoacoustic signals are sensed from sensors that span a three dimensional space and the position of analyte is also determined. | 11-11-2010 |
20100278823 | TREATMENT OF TYPE 1 DIABETES BEFORE AND AFTER EXPRESSION OF PREDISPOSITION MARKERS - The present invention relates generally to the use of compounds, compositions, combinations, kits, and methods for the effective endocytic presentation of immunosuppressive factors for the down regulation of diabetogenic T cells for the treatment of type 1 diabetes. | 11-04-2010 |
20100266508 | STABILIZED GOLD NANOPARTICLE AND CONTRAST AGENT - A kit for providing a contrast enhancer in a mammal for contrasting during imaging of the mammal comprises functionalized gold nanoparticles configured to be directed to one or more of a target organ, tissue and lesion of the mammal. | 10-21-2010 |
20100252721 | OPTICAL SPECTROSCOPY DEVICE FOR NON-INVASIVE BLOOD GLUCOSE DETECTION AND ASSOCIATED METHOD OF USE - An apparatus for concentrating light and associated method of use is disclosed. This apparatus includes a first outer wall having an anterior end, a posterior end, an inner surface and an outer surface, the inner surface defining an interior portion, the interior portion having an anterior end and a posterior end, and a light source disposed within the interior portion. The first outer wall has an opening in the posterior end, the opening having an opening diameter. The interior portion has a substantially frusto-conical shape and has a cross-sectional diameter at the opening equal to the opening diameter and a second cross-sectional diameter near the anterior end that is less than the opening diameter and the inner surface is photo-reflective. The light passes through a sample through an aperture and a collector lens or a second outer wall. A transmission diffraction grating may be utilized. | 10-07-2010 |
20100248228 | Method for detecting DNA methylation in cancer cells - The present invention provides a detecting method of detecting malignant cells in a patient's specimen or a biological sample. Specifically, the inventive method includes the steps of extracting a genomic DNA, digesting said genomic DNA with one or multiple methylation sensitive restriction enzymes, and amplifying by PCR with one or multiple selected primers. The PCR can be performed in a conventional or a real-time platform. The inventive method can detect leukemia cells in 90% ALL patients at a sensitivity of up to 10 | 09-30-2010 |
20100233124 | BACILLUS BASED DELIVERY SYSTEM AND METHODS OF USE | 09-16-2010 |
20100225834 | ADAPTIVE LENS FOR VISION CORRECTION - An adaptive liquid crystal lens system comprising a first substrate assembly, a second substrate assembly having a continuous phase profile, and a liquid crystal layer disposed between the first and second substrate assemblies. The first substrate assembly includes a first transparent substrate, an alignment layer, and a first conductive layer. The first conductive layer is disposed on the bottom surface of the first transparent substrate and adjacent to the top surface of the alignment layer. The second substrate assembly includes a second transparent substrate, a lens having a grooved surface, and a second conductive layer. The second conductive layer is a continuous layer adjacent to the lens. The liquid crystal layer is received in the grooves of the lens, and is adjacent to the bottom surface of the alignment layer. The alignment layer causes the liquid crystal material in the liquid crystal layer to be in a homeotropic state. | 09-09-2010 |
20100217390 | ROTATOR CUFF BONE-TENDON ALLOGRAFT - The invention provides a biomaterial and a method of selecting a biomaterial for a rotator cuff repair procedure. The biomaterial includes a bone-tendon allograft and the use of the biomaterial in rotator cuff repairs may provide immediate bone-tendon integrity and function, which may result in lower failure rates and enhanced clinical success. | 08-26-2010 |
20100212331 | CRYOPRESERVATION METHOD AND DEVICE - A device and method suitable for the cryopreservation of all types of biological cells is described. In this method, an ultra-fast cooling/warming device system is used to achieve vitrification of individual cells or cell suspensions without cryoprotectant agents (CPA) or with a low concentration of CPAs (<1M), to attenuate the formation of intracellular ice crystal formation during cooling, and to minimize devitrification during subsequent warming. The device system applies oscillating heat pipe (OHP) and nanofluid techniques, and is built through microfabrication. Several devices may be networked to increase the total volume of cell samples that the cryopreservation system can process simultaneously. | 08-26-2010 |
20100197820 | SOY-BASED POLYOLS - The invention provides B-sides of urethane formulations, wherein the B-sides comprise both alcohol and epoxy moieties. Also provided are urethane formulations comprising the B-side of the invention, as well as A-sides comprising isocyanate molecules. | 08-05-2010 |
20100196938 | IMMUNOASSAY FOR VENOM DETECTION INCLUDING NONINVASIVE SAMPLE COLLECTION - Methods and immunoassays for diagnosing a bite or sting of a venomous organism in a patient having symptoms consistent with such a bite or sting are provided. A sample of venom is collected from the area of the suspected bite or sting using a swab and then contacted with an antibody that specifically binds to an antigenic site on venom present in the sample. Binding is then detected. The invention is illustrated by examples showing diagnosis of brown recluse spider bite, distinguishing it from other diagnoses with which it is often confused. This extremely sensitive test can detect venom antigens down to about 20 picograms even after the sample has been shipped and stored for periods of up to three weeks during the summer. | 08-05-2010 |
20100194239 | SYSTEM AND METHOD FOR HARVESTING ENERGY FROM ENVIRONMENTAL VIBRATIONS - Embodiments of the present invention provide a system and a method for increasing the harvested energy from a piezoelectric element exposed to environmental vibrations via a two-prong system. In a first prong, a cantilever beam is tapered and shaped so as to increase and provide an approximately uniform strain on and along the beam, thus resulting in increased voltage. In a second prong of the system and method, a voltage compensating circuit, when used with a voltage inversion circuit of the prior art, increases the harvested power by injecting current to the piezoelectric element after each voltage inversion so as to increase the voltage level. | 08-05-2010 |
20100190951 | SOY-BASED POLYOLS - The invention provides processes for preparing soy-based oligomeric polyols or substituted oligomeric polyols, as well as urethane bioelasteromers comprising the oligomeric polyols or substituted oligomeric polyols. | 07-29-2010 |
20100179667 | SCAFFOLD FOR BONE AND TISSUE REPAIR IN MAMMALS - A mammalian tissue scaffold and method for making a tissue scaffold including a rigid scaffold body of biocompatible glass fibers bonded together and in special alignment to define open channels within the scaffold to allow fluid flow into and within the scaffold. | 07-15-2010 |
20100176789 | HIGH FREQUENCY ANALYSIS OF A DEVICE UNDER TEST - Analyzing a device under test (“DUT”) at higher frequencies. A phase shifter varies the phase of a standing wave on a transmission line coupled to the DUT. The standing wave magnitude is sampled at each of the phase shifts and one or more DUT characteristics are determined as a function of the sampled magnitudes and phase shifts. Further aspects include a related phase shifter comprising a waveguide having a plurality of sub-resonant slots formed therein and having active elements for loading the slots to control the phase shift applied to the signal. | 07-15-2010 |
20100130542 | Composition Comprising a Combination of Omeprazole and Lansoprazole, and a Buffering Agent, and Methods of Using Same - The present disclosure relates to pharmaceutical compositions comprising omeprazole, lansoprazole and sodium bicarbonate. Methods of using such compositions are also provided | 05-27-2010 |
20100128111 | NON-DESTRUCTIVE ROTARY IMAGING - Non-destructive imaging of an object. An imaging head supported on a rotatable arm samples an electric field scattered by the object at a plurality of locations as the arm rotates about a central axis, with the locations corresponding to a defined spatial domain located remotely from the object. One or more processors execute computer-readable instructions for controlling rotation of the arm and generating a multi-dimensional profile representative of the object in the defined spatial domain based on the sampling. | 05-27-2010 |
20100125221 | DEVICE AND METHOD FOR DETERMINING A CAP ARRANGEMENT INDICATING COLOR DISCRIMINATION - A detector located on a positioning tray has a plurality of colored caps placed by a subject being tested. Each cap has a unique resonant circuit which is selectively energized to indicate cap position to the detector so that color discrimination of the subject may be determined. | 05-20-2010 |
20100115640 | Methods for Conditional and Inducible Transgene Espression to Direct the Development of Embryonic, Embryonic Stem, Precursor and Induced Pluripotent Stem Cells - Methods are disclosed in which the expression of a specific gene, or combinations of genes, is controlled spatially and temporally to develop intra- and interspecies chimeras. A transgenic EC/ES/P/iPS cell line is created which conditionally expresses a suicide or compromiser gene configured to compromise all cell lineages except that corresponding to a target tissue/organ. The EC/ES/P/iPS cell line is injected into donor embryos having a specific target gene deficiency or embryos genetically engineered to be complementary compromised in lineages corresponding to the target tissue/organ cell lineages of the EC/ES/P/iPS line. One or more stimuli is provided to the embryo to activate compromiser genes for ablation of non-target tissues/organs of the EC/ES/P/iPS line and target tissues/organs of the host embryo, resulting in a chimeric animal having target tissues/organs derived from the genotype of the transgenic cell line and all remaining tissues/organs derived from the donor embryo. | 05-06-2010 |
20100106233 | BIONANOCOMPOSITE FOR TISSUE REGENERATION AND SOFT TISSUE REPAIR - The present invention provides a bionanocomposite including a pre-selected decellularized tissue crosslinked with a pre-selected nanomaterial. Also provided is a process for fabricating the bionanocomposite. Additionally, applications for using the bionanocomposite as soft tissue repair materials or scaffolds for tissue engineering are described. | 04-29-2010 |
20100094655 | SYSTEM AND METHOD FOR LINKING A WEB-BASED RESOURCE WITH AN ELECTRONIC MEDICAL RECORD - A data processing system and method that, in some cases, include an EMR system and a web server. In some cases, the EMR system includes a plurality of electronic medical records for a plurality of patients. One or more of the electronic medical records may include a URL or HTTP Post message that defines a path to a web-based resource, such as a treatment algorithm or medical calculator. In some embodiments, the URL and/or HTTP Post message is constructed based on information in a patient's medical record. | 04-15-2010 |
20100094066 | GAS PHASE REACTION PROCESS FOR POLYHYDRIC COMPOUNDS - The present invention provides processes for the gas phase conversion of a polyhydric feedstock into an oxygen-containing product. The polyhydric feedstock comprises water and at least one polyhydric compound having from about four to about twelve carbon atoms and more than three hydroxyl groups. Also provided are processes for the separation of the oxygen-containing product from the reaction product mixture. | 04-15-2010 |
20100072414 | MICROFLUIDIC VALVE SYSTEMS AND METHODS - The present disclosure provides a microfluidic valve with a liquid-film-core to open and close one or more dispensing orifices of an ejection nozzle of a microfluidic system, such as an inkjet printhead, to prevent nozzle-clogging. The microfluidic valve employs a non-volatile liquid to control ambient air exposure at a liquid-air interface. Particularly, the microfluidic valve utilizes a microfluidic driving mechanism, such as electrowetting principles or magnetic fields, to control movement of the non-volatile liquid in order to control the ambient air exposure at a liquid-air interface. The valve comprises a non-volatile liquid-film-core, a valve housing including a valve channel and a pair of aligned openings, and a valve control subsystem, whereas the liquid-film-core is movably confined within the valve channel, and the valve control subsystem controls movements of the liquid-film-core within the valve channel to Open and Close the aligned openings. | 03-25-2010 |
20100068550 | HOLLOW STRUCTURES FORMED WITH FRICTION STIR WELDING - A hollow structure, and a method of forming the hollow structure, where the hollow structure includes first and second metal parts, the second metal part having an interior surface and a tapered support member extending from the interior surface. The hollow structure also includes a friction stir welded joint that extends through the first metal part and into the tapered support member. | 03-18-2010 |
20100055019 | CALCIUM PHOSPHATE BODIES AND A PROCESS FOR MAKING CALCIUM PHOSPHATE BODIES - Among the various aspects of the present invention is a process for making calcium phosphate bodies comprising amorphous calcium phosphate, hydroxyapatite or calcium triphosphate, the bodies themselves and the use of such bodies in any of a variety of applications. | 03-04-2010 |
20100041134 | SELF-ASSEMBLING MULTICELLULAR BODIES AND METHODS OF PRODUCING A THREE-DIMENSIONAL BIOLOGICAL STRUCTURE USING THE SAME - Structures and methods for tissue engineering include a multicellular body including a plurality of living cells. A plurality of multicellular bodies can be arranged in a pattern and allowed to fuse to form an engineered tissue. The arrangement can include filler bodies including a biocompatible material that resists migration and ingrowth of cells from the multicellular bodies and that is resistant to adherence of cells to it. Three-dimensional constructs can be assembled by printing or otherwise stacking the multicellular bodies and filler bodies such that there is direct contact between adjoining multicellular bodies, suitably along a contact area that has a substantial length. The direct contact between the multicellular bodies promotes efficient and reliable fusion. The increased contact area between adjoining multicellular bodies also promotes efficient and reliable fusion. Methods of producing multicellular bodies having characteristics that facilitate assembly of the three-dimensional constructs are also provided. | 02-18-2010 |
20100037351 | Alteration of Phospholipase De (PLDe) or Phospholipase Da3 (PLD a3) Expression in Plants - Transgenic plants and seeds with altered expression of phospholipase Dε (PLDε) are described, i.e., plants and seeds either overexpressing or underexpressing PLDε. Methods for producing such transgenic plants and for increasing a plant's ability to capture and utilize nitrogen, increasing a plant's biomass production, increasing the yield of a plant or increasing a plant's ability to grow under hyperosmotic stress by overexpressing PLDε are also disclosed. Further disclosed are transgenic plants and seeds which overexpress phospholipase D alpha3 (PLDα3), methods for producing such transgenic plants and seeds, and methods for increasing a plant's ability to grow under hyperosmotic stress by overexpressing phospholipase D alpha3. | 02-11-2010 |
20100036492 | OSTEOCHONDRAL IMPLANTS, ARTHROPLASTY METHODS, DEVICES, AND SYSTEMS - Implants for resurfacing or repairing one or more articular cartilage bearing surfaces of a biological organism include an engineered tissue and a biocompatible porous substrate secured to the engineered tissue for attaching the implant to a native bone of the biological organism. The engineered tissue includes a scaffold containing a biocompatible material, and a plurality of living chondrocytes supported by the scaffold. Methods for culturing chondrocytes for incorporation into a biocompatible implant are provided. A bioreactor for producing functional cartilaginous tissue from a cell-seeded scaffold and a system for producing functional cartilaginous tissue are also provided. | 02-11-2010 |
20100016583 | COMPOUNDS FOR TREATMENT OF COPPER OVERLOAD - The present invention provides compounds, pharmaceutical compositions, and methods that can be used to treat pathologies that are due to copper overload or to the presence of reactive oxygen species. | 01-21-2010 |
20100002229 | Light Scattering Detector - The invention concerns high sensitivity light scattering detection and its application to evaporative light scattering detection in liquid chromatography. The exemplary embodiment includes a detection cell to accept particles suspended in a gas stream and permit a polarized light beam to pass through a trajectory of the particles and gas stream. A sample light detector is disposed to detect light scattered in the detection cell. A light trap accepts the polarized beam after it passes through the detection cell. The light trap includes an elongated housing through which the polarized beam passes, and light absorptive material within the elongated housing. An absorptive filter is aligned such that the angle of incidence of the light beam upon the filter approximates Brewster's angle and the electric field vector of the beam is aligned with the plane of incidence between the beam and the filter. Other embodiments of the invention provide increased light collection. Embodiments of the invention include temperature-controlled entrance and exit ports that control particle trajectory. Embodiments of the invention include a reference cell disposed between a detection cell and a light trap, and the reference cell includes lensing and a spherical mirror to direct light toward a reference light detector. The reference light detector provides a reference signal that may be used with noise cancellation circuitry, operating in either voltage or current mode, to reduce light source noise in the sample signal. | 01-07-2010 |