HEJ Research Institute
HEJ Research Institute Patent applications | ||
Patent application number | Title | Published |
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20090136434 | Tyrosinase enzyme inhibitors from fungal hydroxylation of tibolone - Seven new and one known metabolites of tibolone were obtained by incubation of tibolone with various fungi. Their structures were elucidated by means of a homo and heteronuclear 2D NMR and by HREI-MS techniques. The relative stereochemistry was deduced by 2D NOESY experiment. These metabolites of tibolone were strong inhibitors of tyrosine enzyme and thus useful in producing skin lightning and preserving fruits and vegetables. | 05-28-2009 |
20080318916 | Novel alpha glucosidase inhibitors from lichens - This invention is directed to a novel method for the inhibition of α-glucosidase enzyme and thus treating diabetes, viral infections, fungal infections, autoimmune function disorders and obesity using compounds derived as lichen metabolites; more specifically, this includes the therapeutic applications of methylorsellinate (2,4-dihydroxy-6-methylbenzoate, Compound I), methyl-β-orinolcarboxylate (2,4-dihydroxy-3,6-dimethylbenzoate, Compound II) and zeorin (6,22-hopanediol, Compound III). | 12-25-2008 |
20080274987 | Novel alpha glucosidase activator, pulicarside 1 - A new ent-kaurane type diterpene glucoside, pulicarside (1) was isolated from | 11-06-2008 |