UNIVERSITY OF WARWICK Patent applications |
Patent application number | Title | Published |
20150017628 | CRYOPRESERVATION OF CELLS IN ABSENCE OF VITRIFICATION INDUCING AGENTS - The present invention relates to a method for cryopreserving biological material. In particular, the method comprises storing the biological material at a cryopreserving temperature in a composition comprising polyvinyl alcohol (PVA). wherein the composition is substantially free of vitrification-inducing agents such as DMSO and glycerol. The invention also provides methods of inhibiting ice recrystallisation and of reducing cell damage during the warming or thawing of a cryopreserved composition comprising biological material. The invention also relates to processes for producing a biological material, and related kits. | 01-15-2015 |
20140234427 | USE OF SYNTHETIC JANUS PARTICLES FOR PREVENTING OR REDUCING CRYSTAL GROWTH - The invention provides a method of preventing or reducing the growth of crystals in a substance which is susceptible to crystal growth in which colloidal particles having an amphiphilic structure, e.g. Janus particles, are contacted with the substance. Colloidal particles suitable for use in the invention include cross-linked, colloidal materials formed from hydrophobic monomers such as acrylates or methacrylates and hydrophilic monomers such as those derived from acrylic and/or methacrylic acid. The colloidal particles find particular use in methods of cryopreservation of biological samples (e.g. cells, tissues or organs), as a texture modifier in frozen food products, in the inhibition of gas hydrate formation, and as scale inhibitors. | 08-21-2014 |
20140167326 | ADDITIVE BUILDING - An additive building method for building a plurality of layers to form a build stack is provided. The method includes creating a variable potential difference between a conducting element at a first voltage potential and an ion source at a second voltage potential, and creating an electric field between the conducting element and the ion source. The electric field passes through the build stack to a nearest surface of the build stack which is nearest a transfer medium. The method further includes accumulating electric charge from the ion source on the nearest surface of the build stack, and transferring deposition material from a transfer medium onto the nearest surface. The strength of the field at the nearest surface of the build stack is controlled in order to cause a homogenous transfer of the deposition material on to the nearest surface. | 06-19-2014 |
20130220412 | TRANSPARENT ELECTRODES FOR SEMICONDUCTOR THIN FILM DEVICES - A method of producing a transparent electrode suitable for use in an organic semiconductor photovoltaic device. First and second silanes ( | 08-29-2013 |
20130065864 | NOVEL IRIDIUM/RHODIUM ANTI-CANCER COMPOUNDS - The present invention relates to novel iridium and/or rhodium containing complexes for use as a cytotoxic, such as an anti-cancer agent. There is also provided a method of preparing said compounds. | 03-14-2013 |
20130040925 | OSMIUM (II) ARENE AZO ANTI-CANCER COMPLEXES - The present invention relates to the use of certain osmium containing complexes such as cytotoxic agents particularly for the treatment of cancer. There is also provided novel osmium containing complexes, as well as pharmaceutical formulations comprising such complexes. | 02-14-2013 |
20120241717 | Organic Photosensitive Optoelectronic Devices - A photosensitive optoelectronic device ( | 09-27-2012 |
20120237109 | HISTOLOGY ANALYSIS - The invention relates to histology analyses, and in particular, to the assessment of pathological tissues to aid in the diagnosis of disease characterised by specific pathologies, for example cancer. The invention provides methods and apparatuses for analysing tissue samples, as well as computer-readable media programmed with software for carrying out these diagnostic methods. | 09-20-2012 |
20120142622 | STAMBOMYCIN AND DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS DRUGS - The present invention relates to Stambomycin compounds, their derivatives and their pharmaceutically acceptable salt thereof. | 06-07-2012 |
20110162113 | ANTIBODIES - The application discloses a method of making an antibody molecule, the antibody containing an immunoglobulin heavy chain comprising a α3 domain or a mu domain, the method comprising: (a) Providing a nucleotide sequence encoding the immunoglobulin heavy chain; (b) Modifying the nucleotide sequence in the region of the nucleotide sequence encoding the C-terminus 18 amino acids of the completed heavy chain to remove, or reduce the effectiveness of, one or more vacuolar targeting signal sequences to form a modified nucleotide sequence; (c) Inserting the modified nucleotide sequence into a host cell; and (d) Causing the host cell to express the modified nucleotide sequence to form the modified antibody heavy chain and secrete the modified antibody heavy chain from the host cell. This improves the secretion of the antibody from, for example, plant cells. Methods of adding J-chain binding activity to antibodies are also provided. The modified antibodies and their use is also disclosed. | 06-30-2011 |
20100173793 | PEPTIDE / PROTEIN IDENTIFICATION USING PHOTOREACTIVE CARRIERS FOR THE IMMOBILISATION OF THE LIGANDS - The invention provides a method of identifying a peptide or protein capable of binding a ligand which comprises: (i) providing a support, the support comprising a photoreactive group; (ii) reacting the photoreactive group with a ligand to attach the ligand to the support and produce a supported ligand; (iii) providing an expression library comprising a plurality of members, each member expressing a different peptide or protein; (iv) screening the expression library to identify one or more peptides or proteins which bind to the ligand; (v) isolating the member or each member of the library which expresses a peptide or protein which binds to the ligand; and (vi) identifying the peptide or protein which binds to the ligand. Supported photo-reactive compounds are disclosed comprising a photo-reactive group attached to a support via a spacer and a dendritic group, the dendritic group comprising attached thereto, optionally via a spacer, at least one further photo-reactive group and/or a second functional group. Compounds comprising photo-reactive groups attached to a support and a protein resistant group attached to the support are also provided, together with kits for carrying out the method of the invention. | 07-08-2010 |
20100024448 | HEAT EXCHANGER - This invention relates to the field of heat-driven cooling devices, heat pumps or thermal transformers, in particular to those devices, known as sorption devices, which employ an ad- or absorbent material as a chemical compressor to raise the pressure of a refrigerant gas. This invention is particularly concerned with a heat exchanger suitable for use as a generator in a sorption device. Embodiments of the invention provide a heat exchanger comprising: a plurality of stacked plate members each plate member being provided with at least one fluid channel therein, each plate member having a channel inlet and a channel outlet associated with each channel of the plate member; a plurality of chambers, the chambers being provided between opposed major faces of respective adjacent plate members, the chambers containing a sorbent material; a thermal fluid inlet in communication with a plurality of the channel inlets and a thermal fluid outlet in communication with a plurality of the channel outlets; and a sorbate inlet and a sorbate outlet in communication with each of the chambers, the fluid channels being provided in fluid isolation from the chambers. | 02-04-2010 |
20080261213 | Assay - The invention relates to a method for screening for pre-eclampsia in a mammal, such as a human, by determining the amount and quality of foetal 2,3 bisphosphoglycerate mutase (2,3 BPGM) present. Reagents and kits for carrying out the method are also provided. | 10-23-2008 |