UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION Patent applications |
Patent application number | Title | Published |
20160036344 | THREE-PHASE BUCK RECTIFIER FOR POWER SUPPLIES - A three-phase alternating current (AC) to direct current (DC) converter may include a three-phase AC filter receiving a three-phase AC power supply, a plurality of three-phase current source rectifiers (CSR) connected in parallel with each other and connected to a three-phase AC filter, and an output filter connected to the CSR's to generate a DC output. Each of the CSRs may include six switches and a free-wheeling diode. Each of the three filtered AC inputs from the three-phase AC filter may be connected via a switch of the six switches to selectably send current into a positive line, and each of three filtered AC inputs from the three-phase AC filter may be connected via another switch of the six switches to selectably receive current from a negative line. The free-wheeling diode may have a cathode connected to the positive line and an anode connected to the negative line. | 02-04-2016 |
20160015688 | COMPOUNDS FOR TREATMENT OF CANCER - The present invention relates to pharmaceutical compositions for treating cancer comprising BRAF inhibitors, (e.g. vemurafenib) and/or MEK inhibitor, (e.g. trametinib, RO5068760), in combination with anti-tubulin compounds of the invention or other known tubulin inhibitors, and using such compositions for treating cancer such as melanoma, drug-resistant cancer, and cancer metastasis. | 01-21-2016 |
20150216105 | FLEX ROLLER-CRIMPER FOR IMPROVED MANAGEMENT AND TERMINATION OF COVER CROPS AND OTHER PLANT MATERIAL - Herein is described an agricultural device that can include a frame; and a plurality of roller-crimping devices supported by the frame arranged in at least one row oriented in a direction that is transverse to a direction of travel of the agricultural device. Each of the plurality of roller-crimping devices having an exterior surface configured to at least partially crush stems of residual plant matter, and being individually movably mounted to the frame such that each of the plurality of roller-crimping devices will move at least vertically with respect to the frame when subjected to a temporary increase in resistance caused by an encounter with a non-uniform region in the field. | 08-06-2015 |
20140363674 | CHLORIDE, BROMIDE AND IODIDE SCINTILLATORS WITH EUROPEAN DOPING - A halide scintillator material is disclosed where the halide may comprise chloride, bromide or iodide. The material is single-crystalline and has a composition of the general formula ABX | 12-11-2014 |
20140361190 | System and Method for Detecting and Positioning A Radioactive Source - The present disclosure describes systems and methods for the detection and positioning of a radioactive source. In an exemplary embodiment, a detector array is placed in a four-quadrant formation to allow for self-shielding of the individual detectors from the radiation emitted by a radiation source. A further embodiment utilizes a fuzzy logic system and method to analyze the gross count response of each individual detector with respect to the other three to thereby determine a generalized location and direction of a radioactive source. | 12-11-2014 |
20140318240 | Soak Chamber and System to Measure the Seed Density Hydration Profile of Seeds - Apparatuses, systems, and methods for measuring the hydration profile of seeds during Soaking. In some example embodiments, the volume change of irregular-shaped seeds during soaking is measured as the difference in the volume for a given chamber and the volume of water to fill a chamber with seeds at pre-defined time intervals. A device according to some example embodiments of the present general inventive concept includes a soak chamber to hold the seed, a water bath as a source of the input water, and a measuring tank where the water volume can be determined with a level sensor. The soaking temperature is maintained constant by water baths with a circulating tank surrounding the soak chamber to reduce heat loss. | 10-30-2014 |
20140297546 | METHOD AND APPARATUS FOR PREDICTING OBJECT PROPERTIES AND EVENTS USING SIMILARITY-BASED INFORMATION RETRIEVAL AND MODELING - Method and apparatus for predicting properties of a target object comprise application of a search manager for analyzing parameters of a plurality of databases for a plurality of objects, the databases comprising an electrical, electromagnetic, acoustic spectral database (ESD), a micro-body assemblage database (MAD) and a database of image data whereby the databases store data objects containing identifying features, source information and information on site properties and context including time and frequency varying data. The method comprises application of multivariate statistical analysis and principal component analysis in combination with content-based image retrieval for providing two-dimensional attributes of three dimensional objects, for example, via preferential image segmentation using a tree of shapes and to predict further properties of objects by means of k-means clustering and related methods. By way of example, one of a criminal activity and a fraudulent activity event, an intrusion event and a fire event and residual objects may be predicted and located and qualified such that, for example, properties of the residual objects may be qualified, for example, via black body radiation and micro-body databases including charcoal assemblages. | 10-02-2014 |
20140296286 | COMPOUNDS WITH INCREASED SPECIFICITY FOR THE TREATMENT OF GLIOMA - Disclosed are compounds for the treatment of cancer. Compounds disclosed herein are particularly effective for the selective inhibition of glioma cells. | 10-02-2014 |
20140268934 | THREE-PHASE BUCK RECTIFIER FOR POWER SUPPLIES - A three-phase alternating current (AC) to direct current (DC) converter may include a three-phase AC filter receiving a three-phase AC power supply, a plurality of three-phase current source rectifiers (CSR) connected in parallel with each other and connected to a three-phase AC filter, and an output filter connected to the CSR's to generate a DC output. Each of the CSRs may include six switches and a free-wheeling diode. Each of the three filtered AC inputs from the three-phase AC filter may be connected via a switch of the six switches to selectably send current into a positive line, and each of three filtered AC inputs from the three-phase AC filter may be connected via another switch of the six switches to selectably receive current from a negative line. The free-wheeling diode may have a cathode connected to the positive line and an anode connected to the negative line. | 09-18-2014 |
20140249300 | Metal Catalyzed Oxidation of Lignin and Related Compounds - Disclosed are methods for the benzylic oxidation of the lignin and related compounds. The methods include contacting lignin with a mixture containing manganese and iron, in the presence of oxygen to produce a carboxylic acid from lignin or a related compound. In some embodiments, the mixture includes cobalt. | 09-04-2014 |
20140249155 | SPECTINAMIDES AS ANTI-TUBERCULOSIS AGENTS - Novel 3′-deoxy-3′-acylaminospectinomycin compounds are described. Also described are methods of using the 3′-deoxy-3-acylaminospectinomycin compounds and other spectinomycin analogs in treating tuberculosis and in treating microbial infections. | 09-04-2014 |
20140238155 | SYSTEMS AND METHODS FOR LASER ASSISTED SAMPLE TRANSFER TO SOLUTION FOR CHEMICAL ANALYSIS - Systems and methods are described for laser ablation of an analyte from a specimen and capturing of the analyte in a dispensed solvent to form a testing solution. A solvent dispensing and extraction system can form a liquid microjunction with the specimen. The solvent dispensing and extraction system can include a surface sampling probe. The laser beam can be directed through the surface sampling probe. The surface sampling probe can also serve as an atomic force microscopy probe. The surface sampling probe can form a seal with the specimen. The testing solution including the analyte can then be analyzed using an analytical instrument or undergo further processing. | 08-28-2014 |
20140221479 | SARMS AND METHOD OF USE THEREOF - This invention is directed to a feed composition and method of affecting the carcass composition by increasing the lean mass, reducing the fat mass, and/or reducing the percent fat mass comprising SARM compounds. | 08-07-2014 |
20140220066 | GROUP A STREPTOCOCCUS MULTIVALENT VACCINE - Immunogenic compositions are provided herein that are useful for inducing an immune response specific against group A | 08-07-2014 |
20140213623 | COMPOUNDS FOR TREATMENT OF CANCER - The present invention relates to a compound of formula XXII and a compound of formula 17ya, which are defined as anywhere in the specification, to a composition comprising the same, and to a method of using thereof in the treatment of various forms of cancer. | 07-31-2014 |
20140206714 | LPA2 RECEPTOR-SPECIFIC BENZOIC ACID DERIVATIVES - Disclosed are compounds effective for inhibiting cellular apoptosis and for protecting cells and tissues from the apoptotic effects of chemotherapeutic agents and/or ionizing radiation. Compounds of the invention act as agonists of the LPA | 07-24-2014 |
20140205676 | METHOD OF TISSUE REPAIR USING A COMPOSITE MATERIAL - A composite biocompatible hydrogel material includes a porous polymer matrix, the polymer matrix including a plurality of pores and providing a Young's modulus of at least 10 GPa. A calcium comprising salt is disposed in at least some of the pores. The porous polymer matrix can comprise cellulose, including bacterial cellulose. The composite can be used as a bone graft material. A method of tissue repair within the body of animals includes the steps of providing a composite biocompatible hydrogel material including a porous polymer matrix, the polymer matrix including a plurality of pores and providing a Young's modulus of at least 10 GPa, and inserting the hydrogel material into cartilage or bone tissue of an animal, wherein the hydrogel material supports cell colonization in vitro for autologous cell seeding. | 07-24-2014 |
20140162206 | METHODS AND SYSTEMS COMBINING AC ELECTROOSMOSIS WITH DIELECTROPHORESIS TO ENHANCE DELIVERY OF ACTIVE AGENTS INTO INTRAORAL STRUCTURES - Methods and systems for delivering an active agent into an intraoral structure are disclosed. One embodiment of a method for implementing the subject matter described herein includes generating an electrical signal that includes a first frequency, a second frequency, and a third frequency, and supplying the electrical signal to an embedded circuit contained in an intraoral delivery tray, wherein the embedded circuit includes at least one electrode that includes projections positioned proximally to a surface of an intraoral structure. The method further includes providing the first frequency and the second frequency to the at least one electrode to generate an electrical field that electrically motivates the active agent suspended in a fluid medium contained in the intraoral delivery tray toward the intraoral structure via dielectrophoresis and providing the third frequency to the at least one electrode to increase the uptake of the active agent into intraoral structure via alternating current electroosmosis. | 06-12-2014 |
20140161858 | Multigraft Copolymers as Superelastomers - Thermoplastic elastomer compositions are described comprising multigraft copolymers. The multigraft copolymers can comprise a rubbery polymeric backbone and a plurality of glassy polymeric side chains, each attached at one of a plurality of branch points randomly spaced along the backbone. The copolymer materials have high tensile strength, high strain at break, and low residual strain after elongation. The compositions can be used as adhesives and in a wide variety of high tech, medical, and commodity applications. | 06-12-2014 |
20140147371 | CARBONATION OF METAL SILICATES FOR LONG-TERM CO2 SEQUESTRATION - In a preferred embodiment, the invention relates to a process of sequestering carbon dioxide. The process comprises the steps of: (a) reacting a metal silicate with a caustic alkali-metal hydroxide to produce a hydroxide of the metal formerly contained in the silicate; (b) reacting carbon dioxide with at least one of a caustic alkali-metal hydroxide and an alkali-metal silicate to produce at least one of an alkali-metal carbonate and an alkali-metal bicarbonate; and (c) reacting the metal hydroxide product of step (a) with at least one of the alkali-metal carbonate and the alkali-metal bicarbonate produced in step (b) to produce a carbonate of the metal formerly contained in the metal silicate of step (a). | 05-29-2014 |
20140134668 | ANTIMICROBIAL AND ANTI-INFLAMMATORY ACTIVITY OF SWITCHGRASS-DERIVED EXTRACTIVES - Switchgrass is an increasingly important biofuel crop, but knowledge of switchgrass fungal pathogens is not extensive. The purpose of this research was to identify the fungal pathogens that decrease crop yield of switchgrass grown in Tennessee and to investigate a potential sustainable disease management strategy from a value-added by-product of the switchgrass biofuel conversion process. The specific objectives were 1) to identify and characterize prevalent fungal pathogens of switchgrass in Tennessee, 2) assess switchgrass seed produced in the United States for seedborne fungal pathogens, and 3) evaluate switchgrass extractives for antimicrobial activity against plant pathogens. | 05-15-2014 |
20140134274 | SELECTIVE ANDROGEN RECEPTOR MODULATOR AND CHEMOTHERAPEUTIC AGENT FOR TREATING MUSCLE WASTING IN CANCER PATIENTS - This invention provides use of a SARM compound or a composition comprising the same in treating and preventing muscle wasting in patients with non-small cell lung cancer (NSCLC); treating pre-cachexia or early cachexia (preventing muscle wasting in a cancer patient); treating and preventing loss of physical function due to cancer or cancer therapy; increase of physical function; and increasing survival in a patient with NSCLC, wherein the patients are subjected to cancer therapy. | 05-15-2014 |
20140134103 | TREATMENT AND PROPHYLAXIS OF AMYLOIDOSIS - Methods useful for effecting prophylaxis or treatment of amyloidosis, including AA Amyloidosis and AL amyloidosis, by administering peptides comprising neoepitopes, such as AA fragments from a C-terminal region of AA, and antibodies specific for neoepitopes of aggregated amyloid proteins, for example, antibodies specific for the C-terminal region of AA fibrils. Antibodies for inhibition of formation and/or increasing clearance of amyloid deposits in a patient thus effecting prophylaxis or treating amyloid disease. | 05-15-2014 |
20140073833 | METHODS, SYSTEMS AND COMPUTER READABLE STORAGE MEDIA STORING INSTRUCTIONS FOR DETERMINING PATIENT SPECIFIC TREATMENT PLANNING MARGINS - Methods, systems and computer-readable storage media relate to determining individualized treatment planning margins. The methods may include processing motion data of a target obtained from at least one marker for one or more periods. Each period may include a plurality of time intervals. The processing may include processing the motion data to determine an isocenter for each time interval along at least one of the axes of motion. The axes can include the x axis, the y axis, and/or the z axis. The method may include determining motion prediction data for each of the at least one of the axes; and determining treatment planning margins for each of the at least one of the axes based on the motion prediction data. The individualized treatment margins can be smaller and more optimal because the treatment margins can incorporate patient specific patterns of motion of a target (e.g., an organ). | 03-13-2014 |
20140072965 | 1, 2-Dichloropropane-to-Propene Reductive Dehalogenase Genes - The invention is directed to novel reductive dehalogenase genes encoding for reductive dehalogenases, which are capable of dehalogenating halogenated organic compounds and may be useful for environmental assessment and monitoring, and in the bioremediation of pollutants. In particular, the invention provides isolated polynucleotides of novel reductive dehalogenase genes dcpA and dcpB and fragments thereof as well as isolated polypeptides encoding the DcpA and DcpB proteins or fragments thereof. The invention is also directed to methods of identifying and/or quantifying dechlorinating bacterial organisms or polynucleotides encoding a reductive dehalogenase, such as the dcpA or dcpB polynucleotides or fragments thereof, in a sample. | 03-13-2014 |
20140058424 | NOVEL MICROFABRICATED INSTRUMENTS AND METHODS TO TREAT RECURRENT CORNEAL EROSIONS - In one embodiment, the present invention provides a device and method for treating recurrent corneal erosion. In one embodiment, the method includes the steps of contacting an epithelium layer of a cornea with an array of glass micro-rods including a plurality of sharp features having a length that penetrates a Bowman's layer of the eye, wherein the plurality of sharp features of the array of glass micro-rods produces a plurality of punctures in the Bowman's layer of the eye that are of micro-scale or less. In another embodiment, the present invention provides a method and device for drug delivery. In one embodiment, the device includes an array of glass micro-rods, wherein at least one glass micro-rod of the array of glass micro-rods includes a sharp feature opposite a base of the array of glass micro-rods, wherein the sharp feature includes a treated surface for delivering a chemical compound to the eye. | 02-27-2014 |
20140057936 | LPA2 Receptor-Specific Benzoic Acid Derivatives - Disclosed are compounds effective for inhibiting cellular apoptosis and for protecting cells and tissues from the apoptotic effects of chemotherapeutic agents and/or ionizing radiation. Compounds of the invention act as agonists of the LPA | 02-27-2014 |
20140042373 | TRANSPARENT CONDUCTIVE NANO-COMPOSITES - The present invention, in one embodiment, provides a method of forming an organic electric device that includes providing a plurality of carbon nanostructures; and dispersing the plurality of carbon nanostructures in a polymeric matrix to provide a polymeric composite, wherein when the plurality of carbon nanostructures are present at a first concentration an interface of the plurality of carbon nanostructures and the polymeric matrix is characterized by charge transport when an external energy is applied, and when the plurality of carbon nanostructures are present at a second concentration the interface of the plurality of carbon nanostructures and the polymeric matrix are characterized by exciton dissociation when an external energy is applied, wherein the first concentration is less than the second concentration. | 02-13-2014 |
20140020141 | MODE-SYNTHESIZING ATOMIC FORCE MICROSCOPY AND MODE-SYNTHESIZING SENSING - A method of analyzing a sample that includes applying a first set of energies at a first set of frequencies to a sample and applying, simultaneously with the applying the first set of energies, a second set of energies at a second set of frequencies, wherein the first set of energies and the second set of energies form a multi-mode coupling. The method further includes detecting an effect of the multi-mode coupling. | 01-16-2014 |
20140008294 | SEDIMENT AND DETENTION BASIN DRAINAGE SYSTEM AND METHOD - A fluid drainage system configured for draining a basin impounding fluid and sediment, solids or the like of varying density and turbidity. The system includes a first conduit and a second conduit within or adjacent to the first conduit to form a fluid receiving chamber between the first and second conduits, each conduit having apertures therethrough, with the apertures of the first and second conduits being sized and arranged relative to one another and so configured as to preferentially discharge fluid from the top of a basin, thus providing flow conditions which inhibit the entry of sediment into the system so as to maximize the retention of sediment within the basin and reduce turbidity and Total Suspended Sediment in the discharged fluid. | 01-09-2014 |
20140007293 | Inducible Plant Promoters and the Use Thereof | 01-02-2014 |
20140005263 | TREATING ANDROGEN DECLINE IN AGING MALE (ADAM)-ASSOCIATED CONDITIONS WITH SARMS | 01-02-2014 |
20140005109 | Therapeutic Compositions and Methods for Disorders Associated with Neuronal Degeneration | 01-02-2014 |
20130344027 | MULTI-FUNCTIONAL POLYMERIC MATERIALS AND THEIR USES - Multifunctional polymers are disclosed having a smart segment and a biodegradable segment. Advantageously, the biodegradable segment includes a hydrophilic segment and a hydrophobic segment. Embodiments include combining the multifunctional polymeric material with a biologically active substance in an aqueous loading environment and administering the composition as a drug delivery vehicle to a human subject. | 12-26-2013 |
20130340116 | SWITCHGRASS PROMOTER AND USES THEREOF - The subject application provides polynucleotides, compositions thereof and methods for regulating gene expression in a plant. Polynucleotides disclosed herein comprise novel sequences for a promoter that initiates transcription of an operably linked nucleotide sequence. Thus, various embodiments of the invention comprise the nucleotide sequence of SEQ ID NO: 1 or 2 or fragments thereof that are capable of driving the expression of an operably linked nucleic acid sequence. | 12-19-2013 |
20130324508 | BIOMARKER FOR PROSTATE CANCER AND METHOD OF USING THE SAME - The present invention relates to a biomarker for characterizing prostate cancer and method of using the same. More particularly, the invention relates to method of using a membrane-associated C family G protein-coupled receptor GPRC6A as biomarker of characterizing prostate cancer progression. The present invention also provides a kit for detecting prostate cancer in a subject. | 12-05-2013 |
20130310861 | RETINAL INSTRUMENT - In one embodiment, the present invention provides a method of removing scar tissue from an eye that includes inserting a device including an array of micro-rods into an eye, wherein at least one glass micro-rod of the array of glass micro-rods includes a sharp feature; contacting a scar tissue with the array of micro-rods; and removing the array of micro-rods and the scar tissue from the eye. In another embodiment, the present invention provides a medical device for engaging a tissue including and an array of glass micro-rods, wherein at least one glass micro-rod of the array of glass micro-rods includes a sharp feature opposite a base of the array of glass micro-rods that is connected to the cannula, wherein the sharp feature of the at least one micro-rod is angled from a plane that is normal to a face of the base of the array of glass micro-rods. | 11-21-2013 |
20130298701 | SYSTEMS AND METHODS FOR LASER ASSISTED SAMPLE TRANSFER TO SOLUTION FOR CHEMICAL ANALYSIS - Systems and methods are described for laser ablation of an analyte from a specimen and capturing of the analyte in a dispensed solvent to form a testing solution. A solvent dispensing and extraction system can form a liquid microjunction with the specimen. The solvent dispensing and extraction system can include a surface sampling probe. The laser beam can be directed through the surface sampling probe. The surface sampling probe can also serve as an atomic force microscopy probe. The surface sampling probe can form a seal with the specimen. The testing solution including the analyte can then be analyzed using an analytical instrument or undergo further processing. | 11-14-2013 |
20130298297 | PHK 6 cornus kousa 'Pam's Mountain Bouquet' - A new and distinct cultivar of flowering dogwood, which has fused bracts is provided. This dogwood is botanically known as | 11-07-2013 |
20130261018 | INTERFERON GENE SIGNATURE AND METHODS OF USE THEREOF - The present invention is a method and kit for determining responsiveness of a subject to treatment with a Type I interferon based upon the expression of gene signatures shown to be stimulated by interferon. A method for testing the propensity of a test compound to induce a Type I interferon response is also provided. | 10-03-2013 |
20130216779 | Nanostructures from Laser-Ablated Nanohole Templates - Solution casting a nanostructure. Preparing a template by ablating nanoholes in a substrate using single-femtosecond laser machining. Replicating the nanoholes by applying a solution of a polymer and a solvent into the template. After the solvent has substantially dissipated, removing the replica from the substrate. | 08-22-2013 |
20130207620 | Adaptive Controller for STATCOM to Enhance Voltage Stability - An adaptive controller for a static compensator (STATCOM) to enhance voltage stability comprises an outer voltage regulator loop and an inner current regulator loop. Each of the outer loop and the inner loop comprises a proportional integral controller. The outer loop adjusts proportional and integral control gains of voltage regulator. The inner loop adjusts proportional arid integral parts of current regulator gains. The automatic adjustment of these regulator gains is adaptively determined such that the voltage at the controlled bus follows a desired voltage, reference curve over time returning to a desired steady-state condition under various disturbances such as changes in load and/or transmission network. Thus, the adaptive controller can achieve a plug-and-play feature for a STATCOM without human intervention. | 08-15-2013 |
20130197049 | COMPOUNDS FOR TREATMENT OF CANCER - The present invention relates to novel compounds having anti-cancer activity, methods of making these compounds, and their use for treating cancer and drug-resistant tumors, e.g. melanoma, metastatic melanoma, drug resistant melanoma, prostate cancer and drug resistant prostate cancer. | 08-01-2013 |
20130189336 | Cosmetic Compositions Including Ivy Derived Nanoparticles - Ivy derived nanoparticles and methods for their preparation and use are described herein. Further described herein are cosmetic compositions containing the ivy derived nanoparticles and methods for their use as sunscreens. | 07-25-2013 |
20130173632 | METHOD AND APPARATUS FOR PREDICTING OBJECT PROPERTIES AND EVENTS USING SIMILARITY-BASED INFORMATION RETRIEVAL AND MODELING - Method and apparatus for predicting properties of a target object comprise application of a search manager for analyzing parameters of a plurality of databases for a plurality of objects, the databases comprising an electrical, electromagnetic, acoustic and thermal spectral database (ESD), a micro-body assemblage database (MAD) and a database of image data whereby the databases store data objects containing identifying features, source information and information on site properties and context including time and frequency varying data. The method comprises application of multivariate statistical analysis and principal component analysis in combination with content-based image retrieval for providing two-dimensional attributes of three dimensional objects, for example, via preferential image segmentation using a tree of shapes and to predict further properties of objects by means of k-means clustering and related methods. By way of example, an evidence tree display showing a target object linked by a pathway to a predicted property comprises a similarity value, a speculation value and a model-based rank. | 07-04-2013 |
20130159310 | METHOD AND APPARATUS FOR PREDICTING OBJECT PROPERTIES AND EVENTS USING SIMILARITY-BASED INFORMATION RETRIEVAL AND MODELING - Method and apparatus for predicting properties of a target object comprise application of a search manager for analyzing parameters of a plurality of databases for a plurality of objects, the databases comprising an electrical, electromagnetic, acoustic spectral database (ESD), a micro-body assemblage database (MAD) and a database of image data whereby the databases store data objects containing identifying features, source information and information on site properties and context including time and frequency varying data. The method comprises application of multivariate statistical analysis and principal component analysis in combination with content-based image retrieval for providing two-dimensional attributes of three dimensional objects, for example, via preferential image segmentation using a tree of shapes and to predict further properties of objects by means of k-means clustering and related methods. By way of example, one of a criminal activity and a fraudulent activity event, an intrusion event and a fire event and residual objects may be predicted and located and qualified such that, for example, properties of the residual objects may be qualified, for example, via black body radiation and micro-body databases including charcoal assemblages. | 06-20-2013 |
20130159309 | METHOD AND APPARATUS FOR PREDICTING OBJECT PROPERTIES AND EVENTS USING SIMILARITY-BASED INFORMATION RETRIEVAL AND MODELING - Method and apparatus for predicting properties of a target object comprise application of a search manager for analyzing parameters of a plurality of databases for a plurality of objects, the databases comprising an electrical, electromagnetic, acoustic spectral database (ESD), a micro-body assemblage database (MAD) and a database of image data whereby the databases store data objects containing identifying features, source information and information on site properties and context including time and frequency varying data. The method utilizes a model comprising application of multivariate statistical analysis and principal component analysis in combination with content-based image retrieval for providing two-dimensional attributes of three dimensional objects, for example, via preferential image segmentation using a tree of shapes and to predict further properties of objects by means of k-means clustering and related methods. | 06-20-2013 |
20130143821 | HYDROPHOBICALLY-MODIFIED HYALURONAN AND METHODS OF MAKING AND USING THEREOF - Described herein are modified hyaluronans or the pharmaceutically-acceptable salt or ester thereof, wherein the modified hyaluronan comprises at least one hydrophobic polypeptide covalently bonded to hyaluronan. The modified hyaluronans can be used as viscosupplements in a number of medical applications. The modified hyaluronans can also be used in several biological and medical applications. Methods for preparing the modified hyaluronans are also provided herein. | 06-06-2013 |
20130131994 | METHOD AND APPARATUS FOR MOBILE DISASTER VICTIM IDENTIFICATION - Mobile telecommunications or personal computing apparatus may be specially programmed for predicting whether an unknown biological specimen of an individual to be identified originates from or is related to a member of a particular family. The apparatus may comprise an input device including a barcode reader and a virtual touch screen keyboard whereby DNA profile or mass spectrometry test data may be entered among other data for an individual to be identified, for example, a missing person, victim, crime perpetrator or other unknown individual in hypothetical relationship to another individual or to a family pedigree of typed family members. The typed family pedigree in relation to the individual to be identified in hypothetical relation may be displayed on an output display of the apparatus including at least two different profile typing indicators for each displayed member of the pedigree. | 05-23-2013 |
20130124526 | METHOD AND APPARATUS FOR PREDICTING OBJECT PROPERTIES AND EVENTS USING SIMILARITY-BASED INFORMATION RETRIEVAL AND MODELING - Method and apparatus for predicting properties of a target object comprise application of a search manager for analyzing parameters of a plurality of databases for a plurality of objects, the databases comprising an, electrical, electromagnetic, acoustic spectral, database (ESD), a micro-body assemblage database (MAD) and a database of image data whereby the databases store data objects containing identifying features, source information and information on site properties and context including time and frequency varying data. The method comprises application of multivariate statistical analysis and principal component analysis in combination with content-based image retrieval for providing two-dimensional attributes of three dimensional objects, for example, via preferential image segmentation using a tree of shapes and to predict further properties of objects by means of k-means clustering and related methods. By way of example, one of a machine component or process failure event, an intrusion event and a fire event and residual objects may be predicted and located and qualified such that, for example, properties of the residual objects may be qualified, for example, via black body radiation and micro-body databases including charcoal assemblages. | 05-16-2013 |
20130123304 | PYRIDINE NON-CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE - Disclosed are compounds of the formula I: | 05-16-2013 |
20130109075 | NOVEL HERBICIDE RESISTANCE GENE | 05-02-2013 |
20130054603 | METHOD AND APPARATUS FOR CLASSIFYING KNOWN SPECIMENS AND MEDIA USING SPECTRAL PROPERTIES AND IDENTIFYING UNKNOWN SPECIMENS AND MEDIA - Method and apparatus for determining a metric for use in predicting properties of an unknown specimen belonging to a group of reference specimen electrical devices comprises application of a network analyzer for collecting impedance spectra for the reference specimens and determining centroids and thresholds for the group of reference specimens so that an unknown specimen may be confidently classified as a member of the reference group using the metric. If a trait is stored with the reference group of electrical device specimens, then, the trait may be predictably associated with the unknown specimen along with any traits identified with the unknown specimen associated with the reference group. | 02-28-2013 |
20130041594 | AUTOMATED DECISION SUPPORT FOR ASSOCIATING AN UNKOWN BIOLOGICAL SPECIMEN WITH A FAMILY - Three methods of predicting whether an unknown biological specimen of a missing person originates from a member of a particular family comprise an initial automated decision support (ADS) algorithm for determining a list of relatives of the missing person for DNA typing and which typing technologies of available technologies to use for a listed relative. The ADS algorithm may be implemented on computer apparatus including a processor and an associated memory. The ADS method comprises determining a set of relatives of available family member relatives for DNA typing via a processor from a stored list of family member relatives according to one of a rule base, a table of hierarchically stored relatives developed based on discriminatory power or by calculating the discriminatory power for available family relatives to type. The ADS method may further comprise comparing at least one set of DNA typing data for the unknown biological specimen to DNA typing data from biological specimens from the determined set of relatives; calculating by the processor a likelihood function that the person is related to the family; and outputting a decision whether or not the person is related to the family. | 02-14-2013 |
20130035610 | SYSTEMS AND METHODS FOR PREDICTING GASTROINTESTINAL IMPAIRMENT - In one embodiment, predicting gastrointestinal impairment involves obtaining intestinal sounds of a patient to generate audio data, identifying predefined spectral events in the audio data that are predictive of subsequent gastrointestinal impairment, the spectral events being defined by predefined parameters, and predicting the likelihood of subsequent gastrointestinal impairment relative to the identified spectral events. | 02-07-2013 |
20130035387 | SARMS AND METHOD OF USE THEREOF - This invention is directed to a feed composition and method of affecting the carcass composition by increasing the lean mass, reducing the fat mass, and/or reducing the percent fat mass comprising SARM compounds. | 02-07-2013 |
20130031644 | AUTONOMOUS LUX REPORTER SYSTEM AND METHODS OF USE - Disclosed are systems for expression of an autonomous lux reporter system in a vertebrate cell, such as mammalian or fish cell. In some examples the lux reporter system is operably connected to a pollutant-inducible DNA response element. Also disclosed are transgenic zebrafish, carrying pollution-inducible response elements, and methods of using such zebrafish to monitor pollutants. | 01-31-2013 |
20130026387 | SYSTEM AND METHOD FOR TRAPPING AND MEASURING A CHARGED PARTICLE IN A LIQUID - A system and method for trapping a charged particle is disclosed. A time-varying periodic multipole electric potential is generated in a trapping volume. A charged particle under the influence of the multipole electric field is confined to the trapping volume. A three electrode configuration giving rise to a 3D Paul trap and a four planar electrode configuration giving rise to a 2D Paul trap are disclosed. | 01-31-2013 |
20130022546 | Peptides that Specifically Target Amyloid Deposits - The present invention provides a novel method of detecting amyloids in a subject. The present invention provides peptides that bind selectively to amyloids and are useful for detecting amyloids and diagnosing and/or monitoring the progression of amyloid mediated conditions. | 01-24-2013 |
20130007911 | ENGINEERING MALE STERILITY OR NON-TRANSGENIC POLLEN - The present invention relates to methods of blocking or reducing genetically modified plant (GMO) pollen flow using a “non-lethal” approach. In this aspect, at least one transgenic polynucleotide of interest is linked to a pollen-ablation construct as described herein. The pollen-ablation construct contains a polynucleotide encoding a restriction enzyme that renders the transgenic pollen unable to fertilize a sexually compatible ovule. | 01-03-2013 |
20120321657 | GROUP A STREPTOCOCCUS MULTIVALENT VACCINE - Immunogenic compositions are provided herein that are useful for inducing an immune response specific against group A | 12-20-2012 |
20120321555 | TREATMENT AND PROPHYLAXIS OF AMYLOIDOSIS - Methods useful for effecting prophylaxis or treatment of amyloidosis, including AA Amyloidosis and AL amyloidosis, by administering peptides comprising neoepitopes, such as AA fragments from a C-terminal region of AA, and antibodies specific for neoepitopes of aggregated amyloid proteins, for example, antibodies specific for the C-terminal region of AA fibrils. Antibodies for inhibition of formation and/or increasing clearance of amyloid deposits in a patient thus effecting prophylaxis or treating amyloid disease. | 12-20-2012 |
20120315671 | EXPRESSION MEDIA FOR PROTEINS IN YEAST SYSTEM - The subject invention provides advantageous new media formulations, methods for their production, methods for cultivating cells using the media as well as compositions thereof and their use for enhanced expression of recombinant proteins. In certain embodiments, the subject invention provides media for use in producing recombinant proteins in yeast systems, such as | 12-13-2012 |
20120283331 | Anti-Inflammatory Quinic Acid Derivatives for Radioprotection/Radiomitigation - Disclosed are methods of use of analogs of quinic acids or shikimic acids for protection from the harmful effects of radiation when administered either prior to radiation exposure, after radiation exposure, or both. These methods are useful for treating humans and animals exposed to radiation and at risk for radiation sickness and/or death as the result of radiation exposure. | 11-08-2012 |
20120253704 | METHOD AND APPARATUS FOR FATIGUE AND VISCOELEASTIC PROPERTY TESTING OF ASPHALT MIXTURES USING A LOADED WHEEL TESTER - A loaded wheel tester for testing asphalt mixtures comprises a loaded wheel tester having additional means for attachment to specimens under test to provide a measurement of tensile strain and for attachment between a frame of the loaded wheel tester and the loaded wheel to determine position of the loaded wheel over time. Output results demonstrate that viscoelastic and fatigue properties of asphalt mixtures are obtained in equivalent or improved format using a modified loaded wheel tester when compared with known pavement test apparatus and methods. | 10-04-2012 |
20120237096 | METHOD AND SYSTEM FOR THE DIAGNOSIS OF DISEASE USING RETINAL IMAGE CONTENT AND AN ARCHIVE OF DIAGNOSED HUMAN PATIENT DATA - A method for diagnosing diseases having retinal manifestations including retinal pathologies includes the steps of providing a CBIR system including an archive of stored digital retinal photography images and diagnosed patient data corresponding to the retinal photography images, the stored images each indexed in a CBIR database using a plurality of feature vectors, the feature vectors corresponding to distinct descriptive characteristics of the stored images. A query image of the retina of a patient is obtained. Using image processing, regions or structures in the query image are identified. The regions or structures are then described using the plurality of feature vectors. At least one relevant stored image from the archive based on similarity to the regions or structures is retrieved, and an eye disease or a disease having retinal manifestations in the patient is diagnosed based on the diagnosed patient data associated with the relevant stored image(s). | 09-20-2012 |
20120220534 | BIOMARKER FOR NEURODEGENERATION IN NEUROLOGICAL DISEASE - The present invention provides a method of detecting or diagnosing a neurodegenerative disease or condition in a subject. Further aspects of the invention provide a method of monitoring a subject over a period of time to detect the development or progress of a neurodegenerative disease or condition. Methods of treating, detecting or diagnosing a neurodegenerative disease or condition in a subject are also provided. | 08-30-2012 |
20120190650 | Inhibitors of Autotaxin - Stabilized benzyl phosphonic acid and naphthyl phosphonic acid analog compounds are effective in inhibiting the activity of autotaxin. | 07-26-2012 |
20120189997 | FLEXIBLE AND RIGID ENDOSCOPIC TRAINING DEVICE (FRED) - An anatomically realistic model for training minimally invasive procedures. The model includes an outer shell resembling the appropriate animal or human being with openings for accessing the interior cavity of the shell. Modules within the interior cavity are operably connected to the openings to permit external access to the modules. The modules comprise different mechanical components configured to represent an organ or anatomical feature. Spacers within the interior cavity provide structure and maintain placement of the modules and sufficiently realistic tactile feedback during an endoscopic procedure. | 07-26-2012 |
20120135086 | METHOD OF TISSUE REPAIR USING A COMPOSITE MATERIAL - A composite biocompatible hydrogel material includes a porous polymer matrix, the polymer matrix including a plurality of pores and providing a Young's modulus of at least 10 GPa. A calcium comprising salt is disposed in at least some of the pores. The porous polymer matrix can comprise cellulose, including bacterial cellulose. The composite can be used as a bone graft material. A method of tissue repair within the body of animals includes the steps of providing a composite biocompatible hydrogel material including a porous polymer matrix, the polymer matrix including a plurality of pores and providing a Young's modulus of at least 10 GPa, and inserting the hydrogel material into cartilage or bone tissue of an animal, wherein the hydrogel material supports cell colonization in vitro for autologous cell seeding. | 05-31-2012 |
20120128571 | CARBONATION OF METAL SILICATES FOR LONG-TERM CO2 SEQUESTRATION - In a preferred embodiment, the invention relates to a process of sequestering carbon dioxide. The process comprises the steps of: (a) reacting a metal silicate with a caustic alkali-metal hydroxide to produce a hydroxide of the metal formerly contained in the silicate; (b) reacting carbon dioxide with at least one of a caustic alkali-metal hydroxide and an alkali-metal silicate to produce at least one of an alkali-metal carbonate and an alkali-metal bicarbonate; and (c) reacting the metal hydroxide product of step (a) with at least one of the alkali-metal carbonate and the alkali-metal bicarbonate produced in step (b) to produce a carbonate of the metal formerly contained in the metal silicate of step (a). | 05-24-2012 |
20120107393 | Pellets for Delivery of Biologically Active Substances - Pellets are made by combining a direct compression binder and a waxy spheronizing agent. The pellets may further contain additional pharmaceutical ingredients and/or a drug. The pellets may be compressed to form tablets or loaded into a capsule shell for oral administration, and the pellets may or may not have an additional coating. | 05-03-2012 |
20120084884 | STABLY TRANSFORMED FERNS AND RELATED METHODS - Methods that provide for stable transformation of fern spores and/or protonemata by | 04-05-2012 |
20120059032 | 1,2,3,4-TETRAHYDROISOQUINOLINE DERIVATIVES EFFECTIVE AS ANTIGLIOMA AGENTS, METHODS OF MAKING, AND THEIR USE - Disclosed are tetrahydroisoquinoline-derivative compounds effective for killing cancer cells, shrinking tumor size, and treating cancer. | 03-08-2012 |
20110278212 | SEDIMENT AND DETENTION BASIN DRAINAGE SYSTEM AND METHOD - A fluid drainage system configured for draining a basin impounding fluid and sediment, solids or the like of varying density and turbidity. The system includes a first conduit and a second conduit within or adjacent to the first conduit to form a fluid receiving chamber between the first and second conduits, each conduit having apertures therethrough, with the apertures of the first and second conduits being sized and arranged relative to one another and so configured as to preferentially discharge fluid from the top of a basin, thus providing flow conditions which inhibit the entry of sediment into the system so as to maximize the retention of sediment within the basin and reduce turbidity and Total Suspended Sediment in the discharged fluid. | 11-17-2011 |
20110268680 | HEAT STABLE PROTEIN INGREDIENTS - The subject invention pertains to methods of making crosslinked protein-carbohydrate conjugates (CPCCs) and uncrosslinked protein-carbohydrate conjugates (PCCs) that are heat, pH and salt stable. Methods of stabilizing CPCCs and PCCs are also provided. The PCCs and CPCCs formed according to the methods disclosed herein are useful in the food industry and for loading with substances of interest. | 11-03-2011 |
20110245372 | Rubber-Modified Cementitious Substance and Method of Making the Same - Rubber-modified cementitious substances and various methods of making such substances or components thereof. One embodiment of the substance includes a mix of cement and composite particles, wherein essentially each of the composite particles has a rubber core enclosed in an inorganic exterior and wherein the rubber core is chemically coupled to the inorganic exterior. The chemical coupling between the rubber core and the inorganic exterior and the bonding between the inorganic exterior and the cement result in a rubber-modified cementitious substance that has greater strength than comparable conventional rubber-modified cementitious substances. One embodiment of the method of making a rubber-modified cementitious substance includes (1) reacting a coupling agent with rubber particles and inorganic particles to yield composite particles, wherein essentially each of the composite particles has a rubber core enclosed in an inorganic exterior and (2) combining the composite particles with a cementitious substance to yield a rubber-modified cementitious substance. | 10-06-2011 |
20110224408 | TREATMENT AND PROPHYLAXIS OF AMYLOIDOSIS - Methods useful for effecting prophylaxis or treatment of amyloidosis, including AA Amyloidosis and AL amyloidosis, by administering peptides comprising neoepitopes, such as AA fragments from a C-terminal region of AA, and antibodies specific for neoepitopes of aggregated amyloid proteins, for example, antibodies specific for the C-terminal region of AA fibrils. Antibodies for inhibition of formation and/or increasing clearance of amyloid deposits in a patient thus effecting prophylaxis or treating amyloid disease. | 09-15-2011 |
20110218328 | TREATMENT AND PROPHYLAXIS OF AMYLOIDOSIS - Methods useful for effecting prophylaxis or treatment of amyloidosis, including AA Amyloidosis and AL amyloidosis, by administering peptides comprising neoepitopes, such as AA fragments from a C-terminal region of AA, and antibodies specific for neoepitopes of aggregated amyloid proteins, for example, antibodies specific for the C-terminal region of AA fibrils. Antibodies for inhibition of formation and/or increasing clearance of amyloid deposits in a patient thus effecting prophylaxis or treating amyloid disease. | 09-08-2011 |
20110212554 | TRANSPARENT CONDUCTIVE NANO-COMPOSITES - The present invention, in one embodiment, provides a method of forming an organic electric device that includes providing a plurality of carbon nanostructures; and dispersing the plurality of carbon nanostructures in a polymeric matrix to provide a polymeric composite, wherein when the plurality of carbon nanostructures are present at a first concentration an interface of the plurality of carbon nanostructures and the polymeric matrix is characterized by charge transport when an external energy is applied, and when the plurality of carbon nanostructures are present at a second concentration the interface of the plurality of carbon nanostructures and the polymeric matrix are characterized by exciton dissociation when an external energy is applied, wherein the first concentration is less than the second concentration. | 09-01-2011 |
20110167523 | MATERIALS AND METHODS FOR THE PRODUCTION OF BIODIESEL - The subject invention provides novel microorganisms comprising polynucleotides and polypeptides encoding a methyltransferase. The subject invention provides novel methods for the production of biodiesel. | 07-07-2011 |
20110157550 | Adaptive Photoscreening System - Briefly described, one embodiment of the system, among others, can be implemented as follows. The system includes a computer control system and an environmental light source that is controlled by the computer control system such that an amount of light provided by the environmental light source is adjusted by the computer control so that ocular parameters of an examinee are within a targeted range. Further, the system includes an irradiation system that provides multiple angle and axial eccentricity illuminations and selective wavelength irradiation based upon instructions received from the computer control system, wherein the computer control system instructs the irradiation system to provide different irradiation characteristics for different screening procedures. Also, the system includes an image detection system that captures ocular images of the examinee, wherein the computer control system analyzes captured images and provides results of in-situ analysis. The system can further include a device, for example a lens or lens system, positioned in the system to be between the eye of the examinee and the image detection system during photoscreening for shifting the neutralization of the system to a desired region for a specific population of examinees. Other systems and methods are also provided. | 06-30-2011 |
20110140296 | ROBUST CARBON MONOLITH HAVING HIERARCHICAL POROSITY - A carbon monolith includes a robust carbon monolith characterized by a skeleton size of at least 100 nm, and a hierarchical pore structure having macropores and mesopores | 06-16-2011 |
20110093208 | LEAST-SQUARE DECONVOLUTION (LSD): A METHOD TO RESOLVE DNA MIXTURES - Least Square Deconvolution (LSD) uses quantitative allele peak data, for example, allele peak area, allele peak height and optical density, derived/obtained from a sample containing the DNA of more than one contributor to resolve the best-fit genotype profile of each contributor. The resolution is based on finding the least square fit of the mass ratio coefficients at each locus to come closest to the quantitative allele peak data. Consistent top-ranked mass ratio combinations from each locus can be pooled to form at least one composite DNA profile at a subset of the available loci. The top-ranked DNA profiles can be used to check against the profile of a suspect or be used to search for a matching profile in a DNA database. | 04-21-2011 |
20110053773 | METHODS OF IMPROVING NUTRITIONAL VALUE OF PLANTS - The subject application provides methods for the direct or indirect improvement of levels of key phytonutrients and/or stress tolerance in plants. Methods of providing for the improvement in key phytonutrient levels and/or stress tolerance in plants are provided through the application of safeners, herbicides, fungicides, insecticides, nematicides, miticides, defoliants/desiccants, antibiotics, and/or plant growth regulators to plants. Agricultural products arising from the disclosed methods are also provided. | 03-03-2011 |
20110038948 | Methods of Reducing the Production of Reactive Oxygen Species and Methods of Screening or Identifying Compounds and Compositions that Reduce the Production of Reactive Oxygen Species - The subject application provides methods of identifying compounds, combinations of compounds, compositions, and/or combinations of compositions that are suitable for reducing the production of reactive oxygen species (ROS) in an individual with the proviso that said compound, combination of compounds, composition, or combination of compositions is not a dietary material containing calcium or dietary calcium. Also provided in the subject application are methods of treating diseases or disorders associated with ROS production and methods of reducing ROS production in an individual with the proviso that said compound, combination of compounds, composition, or combination of compositions is not a dietary material containing calcium or dietary calcium. | 02-17-2011 |
20110033559 | Dietary Calcium for Reducing the Production of Reactive Oxygen Species - The subject application provides a method of identifying or screening compounds or compositions suitable for reducing the production of reactive oxygen species (ROS) comprising: a) feeding (or orally administering) compositions comprising dietary material containing dietary calcium (or dietary calcium) to at least one subject; b) measuring intracellular concentrations of calcium in cells of said at least one subject, wherein a decrease of intracellular calcium concentration in said cells of said at least one test subject as compared to the intracellular concentrations of calcium in the cells of at least one control subject is indicative of a compound, composition, combination of compounds or combination of compositions suitable for use in reducing the production of ROS in a subject. Methods of treating ROS-related diseases comprising the oral administration of dietary material containing dietary calcium (or dietary calcium) are also provided. | 02-10-2011 |
20110023183 | Switchgrass Promoter and Uses Thereof - The subject application provides polynucleotides, compositions thereof and methods for regulating gene expression in a plant. Polynucleotides disclosed herein comprise novel sequences for a promoter that initiates transcription of an operably linked nucleotide sequence. Thus, various embodiments of the invention comprise the nucleotide sequence of SEQ ID NO: 1 or 2 or fragments thereof that are capable of driving the expression of an operably linked nucleic acid sequence. | 01-27-2011 |
20110022561 | Method of Organizing and Presenting Data in a Table - Methods of analyzing data are provided. An expert system receives input from at least a first source. Data is imported and analyzed by an expert system, wherein the expert system makes at least one first decision, which characterizes the data based on a rule base. The at least one first decision is displayable and modifiable by a first input from a first source. In response to the first input from the first source, the rule base may be re-applied to make at least one second decision, wherein the at least one second decision is different from the at least one first decision, or the at least one first decision may be accepted. The at least one first decision or the at least one second decision is then displayable and modifiable in response to a first input from a second source. In response to the first input from the second source, the rule base is either re-applied to make at least one third decision, wherein the third decision is different from the second decision, or either the first or second decisions arc accepted. | 01-27-2011 |
20100332475 | METHOD AND APPARATUS FOR PREDICTING OBJECT PROPERTIES AND EVENTS USING SIMILARITY-BASED INFORMATION RETRIEVAL AND MODELING - Method and apparatus for predicting properties of a target object comprise application of a search manager for analyzing parameters of a plurality of databases for a plurality of objects, the databases comprising an electrical, electromagnetic, acoustic spectral database (ESD), a micro-body assemblage database (MAD) and a database of image data whereby the databases store data objects containing identifying features, source information and information on site properties and context including time and frequency varying data. The method comprises application of multivariate statistical analysis and principal component analysis in combination with content-based image retrieval for providing two-dimensional attributes of three dimensional objects, for example, via preferential image segmentation using a tree of shapes and to predict further properties of objects by means of k-means clustering and related methods. By way of example, a fire event and residual objects may be located and qualified such that, for example, properties of the residual objects may be qualified, for example, via black body radiation and micro-body databases including charcoal assemblages. | 12-30-2010 |
20100332474 | METHOD AND APPARATUS FOR PREDICTING OBJECT PROPERTIES AND EVENTS USING SIMILARITY-BASED INFORMATION RETRIEVAL AND MODEL - Method and apparatus for predicting properties of a target object comprise application of a search manager for analyzing parameters of a plurality of databases for a plurality of objects, the databases comprising an electrical, electromagnetic, acoustic spectral database (ESD), a micro-body assemblage database (MAD) and a database of image data whereby the databases store data objects containing identifying features, source information and information on site properties and context including time and frequency varying data. The method comprises application of multivariate statistical analysis and principal component analysis in combination with content-based image retrieval for providing two-dimensional attributes of three dimensional objects, for example, via preferential image segmentation using a tree of shapes and to predict further properties of objects by means of k-means clustering and related methods. By way of example, one of a process failure event, an intrusion event and a fire event and residual objects may be predicted and located and qualified such that, for example, properties of the residual objects may be qualified, for example, via black body radiation and micro-body databases including charcoal assemblages. | 12-30-2010 |
20100332210 | METHOD AND APPARATUS FOR PREDICTING OBJECT PROPERTIES AND EVENTS USING SIMILARITY-BASED INFORMATION RETRIEVAL AND MODELING - Method and apparatus for predicting properties of a target object, in particular, one of an origin and a source, comprise application of a search manager for analyzing parameters of a plurality of databases for a plurality of objects, the databases comprising an electrical, electromagnetic, acoustic spectral database (ESD), a micro-body assemblage database (MAD) and a database of image data whereby the databases store data objects containing identifying features, source information and information on site properties and context including time and frequency varying data. The method comprises application of multivariate statistical analysis and principal component analysis in combination with content-based image retrieval for providing two-dimensional attributes of three dimensional objects, for example, via preferential image segmentation using a tree of shapes and to predict further properties of objects by means of k-means clustering and related methods. By way of example, a fire event and residual objects may be located and qualified such that, for example, properties of the residual objects may be qualified, for example, via black body radiation and micro-body databases including charcoal assemblages. | 12-30-2010 |
20100293667 | Environmental Stress-inducible Promoter and its Application in Crops - The subject application provides polynucleotides, compositions thereof and methods for regulating gene expression in a plant using a promoter that initiates transcription in an inducible manner. In a further aspect of the invention, methods for modulating expression of a gene product in a stably transformed plant comprising the steps of (a) transforming a plant cell with a DNA construct comprising the disclosed promoter or fragments thereof that are capable of driving the expression of an operably linked nucleic acid sequence operably linked to at least one nucleotide sequence; (b) growing the plant cell under plant growing conditions and (c) regenerating a stably transformed plant from the plant cell wherein the induced expression of the operably linked nucleotide sequence alters the phenotype of the plant. | 11-18-2010 |
20100285295 | Wood Adhesives Containing Reinforced Additives for Structural Engineering Products - The present disclosure relates to additives used in conjunction with adhesives to give enhanced performance. Engineered composite wood materials and methods of making such materials are also provided by the subject application. A reinforced adhesive includes an adhesive and an additive material comprising nanoscopic and microscopic materials. | 11-11-2010 |
20100233017 | PRODUCTION OF MAGNESIUM METAL - A process of producing magnesium metal includes providing magnesium carbonate, and reacting the magnesium carbonate to produce a magnesium-containing compound and carbon dioxide. The magnesium-containing compound is reacted to produce magnesium metal. The carbon dioxide is used as a reactant in a second process. In another embodiment of the process, a magnesium silicate is reacted with a caustic material to produce magnesium hydroxide. The magnesium hydroxide is reacted with a source of carbon dioxide to produce magnesium carbonate. The magnesium carbonate is reacted to produce a magnesium-containing compound and carbon dioxide. The magnesium-containing compound is reacted to produce magnesium metal. The invention also relates to the magnesium metal produced by the processes described herein. | 09-16-2010 |
20100205696 | NOVEL HERBICIDE RESISTANCE GENE - The subject invention provides novel polynucleotides and polypeptides encoding a methyltransferase. The subject invention provides novel plants that express the methyltrasferase disclosed herein and are resistant to auxin-based herbicides. The subject invention also provides transgenic plants have been transformed with one or more other herbicide resistance genes such that the plants are resistant to the application of auxin-based herbicides and one or more other herbicides. | 08-12-2010 |
20100153019 | LEAST-SQUARE DECONVOLUTION (LSD): A METHOD TO RESOLVE DNA MIXTURES - Least Square Deconvolution (LSD) uses quantitative allele peak data derived obtained from a sample containing the DNA of more than one contributor to resolve the best-fit genotype profile of each contributor. The resolution is based on finding the least square fit of the mass ratio coefficients at each locus to come closest to the quantitative allele peak data. Consistent top-ranked mass ratio combinations from each locus can be pooled to form at least one composite DNA profile at a subset of the available loci. The top-ranked DNA profiles can be used to check against the profile of a suspect or be used to search for a matching profile in a DNA database. | 06-17-2010 |
20100138374 | AUTOMATED DECISION SUPPORT FOR ASSOCIATING AN UNKNOWN BIOLOGICAL SPECIMEN WITH A FAMILY - Three methods of predicting whether an unknown biological specimen of a missing person originates from a member of a particular family comprise an initial automated decision support (ADS) algorithm for determining a list of relatives of the missing person for DNA typing and which typing technologies of available technologies to use for a listed relative. The ADS algorithm may be implemented on computer apparatus including a processor and an associated memory. The ADS method comprises determining a set of relatives of available family member relatives for DNA typing via a processor from a stored list of family member relatives according to one of a rule base, a table of hierarchically stored relatives developed based on discriminatory power or by calculating the discriminatory power for available family relatives to type. The ADS method may further comprise comparing at least one set of DNA typing data for the unknown biological specimen to DNA typing data from biological specimens from the determined set of relatives; calculating by the processor a likelihood function that the person is related to the family; and outputting a decision whether or not the person is related to the family. | 06-03-2010 |
20100114809 | Method of Organizing and Presenting Data in a Table - Methods of analyzing data are provided. An expert system receives input from at least a first source. Data is imported and analyzed by an expert system, wherein the expert system makes at least one first decision, which characterizes the data based on a rule base. The at least one first decision is displayable and modifiable by a first input from a first source. In response to the first input from the first source, the rule base may be re-applied to make at least one second decision, wherein the at least one second decision is different from the at least one first decision, or the at least one first decision may be accepted. The at least one first decision or the at least one second decision is then displayable and modifiable in response to a first input from a second source. In response to the first input from the second source, the rule base is either re-applied to make at least one third decision, wherein the third decision is different from the second decision, or either the first or second decisions are accepted. | 05-06-2010 |
20100069782 | Passive Microwave Assessment of Human Body Core to Surface Temperature Gradients and Basal Metabolic Rate - A passive microwave thermography apparatus uses passive microwave antennas designed for operation, for example, at WARC protected frequencies of 1.400 to 1.427 GHz and 2.690 to 2.70 GHz (for core body gradient temperature measurement) and 10.68 to 10.700 GHz or higher microwave frequency (for surface body gradient temperature measurement) and a related directional antenna or antenna array to measure microwave radiation emanating from an animal, especially, a human body. The antennae may be radially directed toward a point within or on the surface of a human body for comparison with known temperature distribution data for that point and a given ambient temperature. Each frequency band may provide a plurality of adjacent noise measuring channels for measuring microwave noise naturally emitted by the human body. The apparatus measures short-term changes in, for example, core and body surface temperatures to establish a basal metabolic rate. Changes in core body temperature may be stimulated by the administration of food or certain organic and drug-related substances or stress to induce a change in basal metabolic rate over time. These changes correlate directly with a human subject's metabolism rate at rest and under certain dietary constraints and can be used to determine courses of treatment for obesity, metabolic disease, and other disorders. The apparatus can also be used to remotely monitor patients and subjects without physical contact. | 03-18-2010 |
20100068737 | Enzyme-linked Immunosorbent Assay (ELISA) for Canine Hepcidin - The present invention relates to the use of hepcidin-specific antibodies for the detection of hepcidin in biological samples for the diagnosis of diseases and disorders related to iron metabolism. Kits useful in screening various subjects suspected of having diseases or disorders associated with iron metabolism are also provided. | 03-18-2010 |
20090326020 | COMPOUNDS FOR TREATMENT OF CANCER - Compounds according to formula (I) are disclosed | 12-31-2009 |
20090246191 | Preparation of Purified Covalently Cross-linked Abeta Oligomers and Uses Thereof - The present invention provides a method of purifying cross-linked oligomers. The purified cross-linked oligomers are useful as immunogen for generating and isolating cross-linked oligomer reactive antibodies. The cross-linked oligomer reactive antibodies are useful for detecting amyloid deposition and for diagnosing and treating diseases and conditions associated with amyloid deposition. | 10-01-2009 |
20090162425 | METHODS AND COMPOSITIONS FOR INHIBITING UNDESIRABLE CELLULAR PROLIFERATION BY TARGETED LIPOSOME DELIVERY OF ACTIVE AGENTS - Provided are methods for inhibiting undesirable proliferation of a tumor cell or a tumor in a subject including administering to the subject a composition that includes an effective amount of an active agent, wherein the active agent is entrapped by one or more liposomes, the active agent has activity in inhibiting undesirable proliferation of the tumor cell or the tumor, and the one or more liposomes include one or more targeting agents that preferentially or specifically bind to a binding molecule expressed by the tumor cell or the tumor, present on the tumor cell or the tumor, present in the tumor cell or the tumor, or combinations thereof. Also provided are compositions for treating tumors, particularly gliomas, in a subject in need thereof. | 06-25-2009 |
20090143446 | THIAZOLIDINONE AMIDES, THIAZOLIDINE CARBOXYLIC ACID AMIDES, METHODS OF MAKING, AND USES THEREOF - Substituted thiazolidinone carboxylic acid amides and substituted thiazolidine carboxylic acid amides according to formulae (I) and (II) are disclosed | 06-04-2009 |
20090126897 | METHOD AND APPARATUS FOR SEMI-SOLID MATERIAL PROCESSING - A method of forming a material includes the steps of: vibrating a molten material at an ultrasonic frequency while cooling the material to a semi-solid state to form non-dendritic grains therein; forming the semi-solid material into a desired shape; and cooling the material to a solid state. The method makes semi-solid castings directly from molten materials (usually a metal), produces grain size usually in the range of smaller than 50 μm, and can be easily retrofitted into existing conventional forming machine. | 05-21-2009 |
20090079937 | Adaptive Photoscreening System - Briefly described, one embodiment of the system, among others, can be implemented as follows. The system includes a computer control system and an environmental light source that is controlled by the computer control system such that an amount of light provided by the environmental light source is adjusted by the computer control so that ocular parameters of an examinee are within a targeted range. Further, the system includes an irradiation system that provides multiple angle and axial eccentricity illuminations and selective wavelength irradiation based upon instructions received from the computer control system, wherein the computer control system instructs the irradiation system to provide different irradiation characteristics for different screening procedures. Also, the system includes an image detection system that captures ocular images of the examinee, wherein the computer control system analyzes captured images and provides results of in-situ analysis. Other systems and methods are also provided. | 03-26-2009 |
20090078872 | Doped Carbon Nanostructure Field Emitter Arrays for Infrared Imaging - An infrared imaging device and method for making infrared detector(s) having at least one anode, at least one cathode with a substrate electrically connected to a plurality of doped carbon nanostructures; and bias circuitry for applying an electric field between the anode and the cathode such that when infrared photons are absorbed by the nanostructures the emitted field current is modulated. The detectors can be doped with cesium to lower the work function. | 03-26-2009 |
20090044606 | Robust Carbon Monolith Having Hierarchical Porosity - A carbon monolith includes a robust carbon monolith characterized by a skeleton size of at least 100 nm, and a hierarchical pore structure having macropores and mesopores. | 02-19-2009 |
20090035259 | GROUP A STREPTOCOCCAL VACCINES - The present invention provides methods for eliciting an immune response against Group A streptococci, comprising use of recombinant fusion polypeptides, and compositions thereof, that include a multivalent immunogenic portion of at least two immunogenic polypeptides from Group A streptococci M proteins (which are capable of stimulating a protective immune response against Group A streptococci), and a reiterated polypeptide from the immunogenic portion carboxy-terminal to the immunogenic portion, wherein the carboxy-terminal polypeptide is not required to stimulate an immune response against Group A streptococci. | 02-05-2009 |
20080255213 | THIAZOLIDINONE AMIDES, THIAZOLIDINE CARBOXYLIC ACID AMIDES, AND SERINE AMIDES, INCLUDING POLYAMINE CONJUGATES THEREOF, AS SELECTIVE ANTI-CANCER AGENTS - Substituted thiazolidinone carboxylic acid amides and substituted thiazolidine carboxylic acid amides having a structure | 10-16-2008 |
20080250527 | Antibiotic Resistance Conferrred by a Plant Abc Transporter Gene when Expressed in Transgenic Plants - The use of selectable marker genes, such as the kanamycin resistance encoding neomycin phosphotransferase (nptII), has been invaluable in transgenic plant production. The subject invention provides a new selectable marker gene, an Arabidopsis thaliana ATP binding cassette (ABC) transporter, Atwbc19 and methods of using the gene for the identification of transgenic plants. Since ABC transporters are endogenous to plants, there should be less controversy using Atwbc19, as a selectable marker in transgenic plants with regards to concerns of horizontal gene transfer. | 10-09-2008 |
20080206103 | Method For The Preparation Of Very Stable, Self-Assembled Monolayers On The Surface Of Gold Coated Microcantilevers For Application To Chemical Sensing - Methods for the preparation of a stable, self-assembled monolayer on the silicon surface or metallic coating of a microcantilever are disclosed. The methods produce a microcantilever suitable as a chemical sensor. In a microcantilever produced using one version of the method, a metallic coating is disposed on a side of the microcantilever, a bridging atom is bonded to the metallic coating, a first spacer group is bonded to the bridging atom, a second spacer group is bonded to the bridging atom, and a chemical recognition agent is bonded to the first spacer group. In another version of the method, a silicon surface of a microcantilever is hydrogen terminated, and a calixarene chemical recognition agent is carbon linked to the silicon surface using photochemical hydrosilylation. Among other things, the calixarene may be bonded to a crown ether for ion detection or bonded to a area for the recognition of explosives by hydrogen bonding to nitro groups. | 08-28-2008 |
20080200439 | Methods and compositions for modulating BK channel activity and vasodilation - Methods and compositions are provided for modulating myocyte BK channel activity and for screening for modulators of BK channel activity. The methods and compositions are useful in the treatment of disorders where increasing myocyte BK channel activity can attenuate, revert or prevent the disorder. For example, the methods and compositions are useful for treating disorders ameliorated by increasing vasodilation and blood flow in a subject, in particular, increasing cerebral blood flow. | 08-21-2008 |