Inventors list

Agents list

Assignees list

List by place

Classification tree browser

Top 100 Inventors

Top 100 Agents

Top 100 Assignees

ASTRAZENECA R&D BOSTON

WALTHAM, MA US

1. 20110046108 PYRIMIDINE DERIVATIVES - The invention concerns benzamide compounds of Formula , or a pharmaceutically acceptable salt thereof, where R 02-24-2011
2. 20110034454 MORPHOLINO PYRIMIDINE DERIVATIVES AND THEIR USE IN THERAPY 02-10-2011
3. 20110028498 METHOD FOR EVALUATING PATIENTS FOR TREATMENT WITH DRUGS TARGETING RET RECEPTOR TYROSINE KINASE 02-03-2011
4. 20110028471 COMBINATION THERAPY 238 - There is provided a combination product comprising a VEGFR tyrosine kinase inhibitor and a m TOR-selective kinase inhibitor 02-03-2011
5. 20110015392 PROCESS FOR PREPARING PYRIDONE DERIVATIVES 226 01-20-2011
6. 20110009373 COMPOSITION COMPRISING A COMBINATION OF AN AROMATASE INHIBITOR, A PROGESTIN AND AN OESTROGEN AND ITS USE FOR THE TREATMENT OF ENDOMETRIOSIS 01-13-2011
7. 20110003831 N-(-3-METHOXY-5-METHYLPYRAZIN-2-YL)-2-(4-'1,3,4-OXADIAZOL-2-YL!PHENYL)PYRI- DINE-3 SULPHONAMIDE AS AN ANTICANCER AGENT 01-06-2011
8. 20100331329 BENZAMIDE DERIVATIVES USEFUL AS HISTONE DEACETYLASE INHIBITORS 12-30-2010
9. 20100324040 9-(PYRAZOL-3-YL)-9H-PURINE-2-AMINE AND 3-(PYRAZOL-3-YL) -3H-IMIDAZO[4,5-B] PYRIDIN-5- AMINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF CANCER 12-23-2010
10. 20100317624 HETEROCYCLIC UREA DERIVATIVES AND METHODS OF USE THEREOF 12-16-2010
11. 20100317593 2,3-DIHYDRO-1H-INDENE COMPOUNDS - Provided herein are 2,3-dihydro-1H-indene compounds, methods for making the compounds, pharmaceutical compositions 12-16-2010
12. 20100292222 CHEMICAL COMPOUNDS 751 - The invention concerns bicyclic compounds of Formula STR00001 wherein, R 11-18-2010
13. 20100286181 PYRROLE DERIVATIVES WITH ANTIBACTERIAL ACTIVITY 11-11-2010
14. 20100280048 Some 2-pyrazinone derivatives and their use as inhibitors of neutrophile elastase 11-04-2010
15. 20100278835 NOVEL COMPOUNDS 660 - The invention provides compounds of formula STR00001 wherein R 11-04-2010
16. 20100273811 N-[5-[2-(3,5-Dimethoxyphenyl)ethyl]-1H-pyrazol-3-yl]-4-(3,4-dimethylpipera- zin-1-yl)benzamide and Salts Thereof 10-28-2010
17. 20100267699 CHEMICAL COMPOUNDS - 643 - The invention concerns bicyclic compounds of Formula I STR00001 wherein , R 10-21-2010
18. 20100261723 TRISUBSTITUTED PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF PROLIFERATIVE DISEASES 10-14-2010
19. 20100261719 CHEMICAL COMPOUNDS - In one aspect, the present invention relates to compounds of Formula and to pharmaceutically acceptable salts thereof, wherein: n 10-14-2010
20. 20100261690 NOVEL COMBINATIONS - pharmaceutical product comprising, in combination, a named glucocorticosteroid receptor agonist and a 10-14-2010
21. 20100256105 NOVEL COMPOUNDS - compounds of formula STR00001 wherein n, p, R 10-07-2010
22. 20100256103 NOVEL COMPOUNDS - named compounds of formula STR00001 and pharmaceutical compositions containing them and their use in therapy 10-07-2010
23. 20100249131 MORPHOLINO PYRIMIDINE DERIVATIVES USED IN DISEASES LINKED TO MTOR KINASE AND/OR PI3K 09-30-2010
24. 20100249112 COMBINATION OF CHK AND PARP INHIBITORS FOR THE TREATMENT OF CANCERS 09-30-2010
25. 20100240686 CHEMICAL COMPOUNDS - Compounds of formula : STR00001 which possess cell-cycle inhibitory activity are described 09-23-2010
26. 20100240645 COMBINATION OF CHECKPONIT KINASE (CHK) AND TELANGIECTASIA MUTATED (ATM) INHIBITORS FOR THE TREATMENT OF CANCER 09-23-2010
27. 20100227858 TRISUBSTITUTED PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF PROLIFERATIVE DISEASES 09-09-2010
28. 20100226917 METHODS FOR THE TREATMENT OF HEMATOLOGIC MALIGNANCIES 09-09-2010
29. 20100222344 4-ANILINO-SUBSTITUTED QUINAZOLINE DERIVATIVES AS TYROSINE KINASE INHIBITORS 09-02-2010
30. 20100216791 PYRIDINYLQUINAZOLINAMINE DERIVATIVES AND THEIR USE AS B-RAF INHIBITORS 08-26-2010
31. 20100215618 NOVEL COMPOUNDS - 644 - The invention provides compounds of formula STR00001 wherein R 08-26-2010
32. 20100210648 PYRAZOLYLAMINOPYRIMIDINE DERIVATIVES USEFUL AS TYROSINE KINASE INHIBITORS 08-19-2010
33. 20100204246 5-AMINOPYRAZOL-3-YL-3H-IMIDAZO (4,5-B) PYRIDINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF CANCER 08-12-2010
34. 20100204231 AMINO-THIAZOLYL-PYRIMIDINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF CANCER 08-12-2010
35. 20100197749 CHEMICAL COMPOUNDS - of formula and : STR00001 or pharmaceutically acceptable salts thereof 08-05-2010
36. 20100190745 HETEROCYCLIC UREA DERIVATIVES AND METHODS OF USE THEREOF 07-29-2010
37. 20100179161 PYRAZOLINE DERIVATIVES FOR THE TREATMENT OF TURBERCULOSIS 07-15-2010
38. 20100179150 ANTIBACTERIAL PIPERDINE DERIVATIVES - Compounds of formula and their pharmaceutically acceptable salts are described 07-15-2010
39. 20100173909 PIPERIDINE COMPOUNDS AND USES THEREOF - 596 07-08-2010
40. 20100168143 QUINAZOLINE DERIVATIVES - The invention provided a compound of formula for use in the treatment of disease in particular proliferative diseases such as 07-01-2010
41. 20100160627 NOVEL LACTAMS AND USES THEREOF - Compounds having the formula STR00001 pharmaceutical compositions containing them and their methods of use for the 06-24-2010
42. 20100160325 4-(3-AMINOPYRAZOLE) PYRIMIDINE DERIVATIVES FOR USE AS TYROSINE KINASE INHIBITORS IN THE TREATMENT OF CANCER 06-24-2010
43. 20100158863 TRIAZOLOANILINOPYRIMIDINE DERIVATIVES FOR USE AS ANTIVIRAL AGENTS 06-24-2010
44. 20100152441 COMPOUNDS FOR THE TREATMENT OF MULTI-DRUG RESISTANT BACTERIAL INFECTIONS 06-17-2010
45. 20100152219 PYRAZOLE DERIVATIVES AS INHIBITORS OF RECEPTOR TYROSINE KINASES 06-17-2010
46. 20100152169 4-OXOQUINAZOLIN-3-YL BENZAMIDE DERIVATIVES FOR THE TREATMENT OF CYTOKINE DISEASES 06-17-2010
47. 20100144759 NOVEL N-(FLUORO-PYRAZINYL)-PHENYLSULFONAMIDES AS MODULATORS OF CHEMOKINE RECEPTOR CCR4 06-10-2010
48. 20100144717 2-QUINOLINONE AND 2-QUINOXALINONE-DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS 06-10-2010
49. 20100137397 Chemical Compounds - compound of the formula or a pharmaceutically-acceptable salt: possess glycogen phosphorylase inhibitory activity and accordingly 06-03-2010
50. 20100137313 HETEROCYCLIC DERIVATIVES AND METHODS OF USE THEREOF 06-03-2010
51. 20100137304 NOVEL CRYSTALLINE FORMS OF THE ANTI-CANCER COMPOUND ZD1839 06-03-2010
52. 20100137303 NEW COMPOUND 255 - Compounds of formula and their pharmaceutically acceptable salts are described 06-03-2010
53. 20100105655 NOVEL COMPOUNDS 515 - There is provided novel pyrimidine derivatives of formula STR00001 or pharmaceutically acceptable salts thereof 04-29-2010
54. 20100098763 PHARMACEUTICAL FORMULATION 514 - pharmaceutical formulation comprising the drug 4-[3--4-fluoro-ben- zyl]-2H-phthalazin-1-one in a solid dispersion with 04-22-2010
55. 20100094010 CHEMICAL PROCESS - Processes for preparing compounds of Formula I and IV STR00001 are described 04-15-2010
56. 20100086942 COMPOUNDS - binding members, especially antibody molecules, for CXCL13 04-08-2010
57. 20100075942 N-PHENYL-4-PYRIDIN-2-YL-BENZAMIDE DERIVATIVES AS HISTONE DEACYLASE (HDAC) INHIBITORS FOR THE TREATMENT OF CANCER 03-25-2010
58. 20100069412 PHOSPHONOXY QUINAZOLINE DERIVATIVES AND THEIR PHARMACEUTICAL USE 03-18-2010
59. 20100048543 PYRIMIDINE COMPOUNDS HAVING TIES (TEK) INHIBITORY ACTIVITY 02-25-2010
60. 20100041912 METHOD FOR THE WITTIG REACTION IN THE PREPARATION OF CARBOPROST 02-18-2010
61. 20100035896 Combination of N-(3-methoxy-5-methylpyrazin-2-yl)-2-(4-[1,3,4-oxadiazol-2-yl]phenyl)pyri- dine-3-sulphonamide and an anti-mitotic cytotoxic agent 02-11-2010
62. 20100029643 HETEROCYCLYC SULFONAMIDES HAVING EDG-1 ANTAGONISTIC ACTIVITY 02-04-2010
63. 20100022534 2-BENZIMIDAZOLYL-6-MORPHOLINO-4- (AZETIDINE, PYRROLIDINE, PIPERIDINE OR AZEPINE) PYRIMIDINE DERIVATIVES AS PI3K AND MTOR INHIBITORS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS 01-28-2010
64. 20100022476 PYRAZOLYLAMINO SUBSTITUTED QUINAZOLES FOR THE TREATMENT OF CANCER 01-28-2010
65. 20100016279 BICYCLIC DERIVATIVES FOR USE IN THE TREATMENT OF ANDROGEN RECEPTOR ASSOCIATED CONDITIONS-155 01-21-2010
66. 20100004247 COMBINATION COMPRISING A MEK INHIBITOR AND AN AURORA KINASE INHIBITOR 188 01-07-2010
67. 20100004181 COMBINATION COMPRISING N-(3-METHOXY-5-METHYLPYRAZIN-2-YL)-2-(4-(1,3,4-OXADIAZOL-2-YL)PHENYL) PYRIDINE-3-SULPHONAMIDE AND AN LHRH ANALOGUE AND/OR A BISPHOSPHONATE 01-07-2010
68. 20090325954 2-BENZIMIDAZOLYL-6-MORPHOLINO-4-PHENYLPYRIMIDINE DERIVATIVES AS PI3K AND MTOR INHIBITORS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS 12-31-2009
69. 20090325902 HETEROCYCLIC UREA DERIVATIVES AND METHODS OF USE THEREOF 12-31-2009
70. 20090324601 TARGETED BINDING AGENTS DIRECTED TO PDGFR-ALPHA AND USES THEREOF 12-31-2009
71. 20090318468 PYRAZOLE COMPOUNDS 436 - There is provided novel compounds of formula or : STR00001 or pharmaceutically acceptable salsts thereof 12-24-2009
72. 20090318427 BENZODIAZEPINE DERIVATIVES FOR TREATING HEPATITIS C INFECTION 12-24-2009
73. 20090312556 N-(2-AMINIPHENYL)-4-(5-((ETHYLAMINO)METHYL)-1,2-THIAZOL-2-YL) BENZAMIDE AND N-(2-AMINOPHENYL)-4-(5-((ISOPROPYLAMINO)METHYL)-1,2-THIAZOL-2-YL) BENZAMIDE AS HDAC INHIBITORS 12-17-2009
74. 20090312396 METHODS FOR CANCER TREATMENT USING TAK1 INHIBITORS 12-17-2009
75. 20090312336 DIHYDROPTERIDINE COMPOUNDS AS ANTI PROLIFERATIVE AGENTS 12-17-2009
76. 20090306116 PYRIMIDINE DERIVATIVES FOR THE INHIBITION OF IGF-IR TYROSINE KINASE ACTIVITY 12-10-2009
77. 20090291961 COMBINATION OF AN MEK INHIBITOR AND THE SRC KINASE INHIBITOR AZD0530 FOR USE IN THE TREATMENT OF CANCER 11-26-2009
78. 20090286982 NOVEL SALT-554 - 4--7-methoxy-6-{[1-pipe- ridin-4-yl]oxy}quinazoline difumarate pharmaceutical compositions containing the difumarate 11-19-2009
79. 20090275570 SUBSTITUTED HETEROCYCLES AND THEIR USE AS CHK1, PDK1 AND PAK INHIBITORS 11-05-2009
80. 20090270450 CHEMICAL COMPOUNDS - of formula : STR00001 or pharmaceutically acceptable salts thereof which possess CSF-1R kinase inhibitory activity and are 10-29-2009
81. 20090270390 PYRIMIDINE DERIVATIVES - The invention concerns pyrimidine derivatives of Formula wherein each of p, R 10-29-2009
82. 20090253671 TRICYCLIC DERIVATIVES OF AZETIDINE AND PYRROLE WITH ANTIBACTERIAL ACTIVITY 10-08-2009
83. 20090253616 COMBINATION THERAPY FOR THE TREATMENT OF CANCER 10-08-2009
84. 20090215770 Substituted Quinazoline Derivatives as Inhibitors of Aurora Kinases 08-27-2009
85. 20090209022 Crystal Structure of Ump Kinase and Uses Thereof 08-20-2009
86. 20090203663 CHEMICAL COMPOUNDS - compounds that inhibit a5b1 function processes for their preparation 08-13-2009
87. 20090202568 Binding members for interleukin-4 receptor alpha (IL-4Ra)-173 08-13-2009
88. 20090170849 QUINAZOLINONE DERIVATIVES HAVING B-RAF INHIBITORY ACTIVITY 07-02-2009
89. 20090163525 SUBSTITUTED QUINAZOLINES WITH ANTI-CANCER ACTIVITY 06-25-2009
90. 20090163524 Novel Protein Kinase B Inhibitors - 060 - novel group of compounds of Formula or salts thereof: STR00001 wherein Y, Z 06-25-2009
91. 20090149484 QUINAZOLIN-4-ONE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM 06-11-2009
92. 20090137624 Chemical Compounds - This invention relates to novel compounds having the formula : and to their pharmaceutical compositions and to their methods of use 05-28-2009
93. 20090137601 L-Phenylalanine Derivatives - compounds that inhibit of a5b1 function processes for their preparation 05-28-2009
94. 20090131463 NOVEL COMPOUNDS - The invention provides compounds of formula STR00001 in which R 05-21-2009
95. 20090131444 Aminopiperidine Quinolines and Their Azaisosteric Analogues with Antibacterial Activity 05-21-2009
96. 20090123478 Human antibody molecules for IL-13 - Specific binding members, in particular human anti-IL-13 antibody molecules and especially those which neutralise 05-14-2009
97. 20090123476 TARGETED BINDING AGENTS DIRECTED TO UPAR AND USES THEREOF 05-14-2009
98. 20090123474 COMBINATION OF ANGIOPOIETIN-2 ANTAGONIST AND OF VEGF-A, KDR AND/OR FLTL ANTAGONIST FOR TREATING CANCER 05-14-2009
99. 20090118305 PYRIDINE AND PYRAZINE DERIVATIVES - 083 - The invention concerns pyridine and pyrazine derivatives of Formula I STR00001 or a 05-07-2009
100. 20090118261 QUINAZOLINONE DERIVATIVES AND THEIR USE AS B-RAF INHIBITORS 05-07-2009
101. 20090118220 SUBSTITUTED ADENINES AND THE USES THEREOF 05-07-2009
102. 20090111860 SULFONAMIDE COMPOUNDS USEFUL AS ADG RECEPTOR MODULATORS 04-30-2009
103. 20090111828 L-ALANINE DERIVATIVES - compounds that inhibit of a5b1 function processes for their preparation 04-30-2009
104. 20090105324 IMIDAZOLE DERIVATIVES FOR USE AS EDG-1 ANTAGONISTS 04-23-2009
105. 20090099210 ENANTIOMERS OF SELECTED FUSED HETEROCYCLICS AND USES THEREOF 04-16-2009
106. 20090099203 COMPOSITION 064 - pharmaceutical composition which comprises N--2-pyri- dine-3-sulphonamide with mannitol and/or microcrystalline cellulose is described 04-16-2009
107. 20090099174 COMBINATION 059 - This invention relates to a combination product as defined herein comprising a MEK inhibitor and a mTOR-selective inhibitor 04-16-2009
108. 20090062267 L-ALANINE DERIVATIVES AS a5beta1 ANTAGONISTS 03-05-2009
109. 20090062246 THERAPEUTIC TREATMENT-014 - combination comprising N--2-pyri- dine-3-sulphonamide or a pharmaceutically acceptable salt thereof 03-05-2009
110. 20090060919 BINDING MEMBERS FOR IgE MOLECULES - This invention relates to binding members, especially antibody molecules, for IgE 03-05-2009
111. 20090054469 QUINAZOLINONE DERIVATIVES AND THEIR USE AS B-RAF INHIBITORS 02-26-2009
112. 20090054428 NOVEL PYRIMIDINE DERIVATIVES 965 - The invention concerns compounds of Formula I, or a pharmaceutically acceptable salt thereof, STR00001 where R 02-26-2009
113. 20090054411 4-ANILINOQUINOLINE-3-CARBOXAMIDES AS CSF-1R KINASE INHIBITORS 02-26-2009
114. 20090054398 CHEMICAL COMPOUNDS - new method for treating disorders associated with activation of the Notch signal transduction pathway comprising administering an 02-26-2009
115. 20090054396 SUBSTITUTED THIOPHENES AND USES THEREOF - This invention relates to novel compounds having the structural formula and to their pharmaceutical salts, 02-26-2009
116. 20090054394 POLYMORPHISMS IN MGST3 ARE ASSOCIATED WITH ELEVATED ALAT LEVELS AFTER XIMELAGATRAN TREATMENT 02-26-2009
117. 20090048269 CHEMICAL COMPOUNDS-821 - chemical compounds of the formula STR00001 or pharmaceutically acceptable salts thereof 02-19-2009
118. 20090048203 SUBSTITUTED ADENINES AND THE USES THEREOF 02-19-2009
119. 20090036424 ASSOCIATION BETWEEN HLA-DRBI*07 ALLELE AND SUSCEPTIBILY TO INCREASED LEVELS OF ALAT FOLLOWING XIMELAGATRAN ADMINISTRATION 02-05-2009
120. 20090029991 BENZAMIDE DERIVATIVES USEFUL AS HISTONE DEACETYLASE INHIBITORS 01-29-2009
121. 20090029367 POLYMORPHISMS IN PON1 ARE ASSOCIATED WITH ELEVATED ALANINE AMINOTRANSFERASE LEVELS AFTER XIMELAGATRAN OR TACRINE ADMINISTRATION 01-29-2009
122. 20090023719 PYRIMIDINE DERIVATIVES 934 - compound of formula STR00001 where one of A 01-22-2009
123. 20090012084 3-CINNOLINECARBOXAMIDE DERIVATIVES AND THEIR USE FOR TREATING CANCER 01-08-2009
124. 20080312255 PIPERDINE COMPOUNDS AND USES THEREOF-911 12-18-2008
125. 20080312211 Antibacterial Pyrrolopyridines, Pyrrolopyrimidines and Pyrroloazepines-154 12-18-2008
126. 20080312206 Chemical Compounds-149 - chemical compounds or pharmaceutically acceptable salts thereof of the formula which possess CSF 1R kinase inhibitory activity 12-18-2008
127. 20080306096 Quinazoline Derivatives, Process for Their Preparation and Their Use as Anti-Cancer Agents 12-11-2008
128. 20080293744 Enantiomers of Selected Fused Pyrimidones and Uses in the Treatment and Prevention of Cancer 11-27-2008
129. 20080287475 4-(3-Aminopyrazole) Pyrimidine Derivatives for Use as Tyrosine Kinase Inhibitors in the Treatment of Cancer 11-20-2008
130. 20080287437 Pyrazolylaminopyrimidine Derivatives Useful as Tyrosine Kinase Inhibitors 11-20-2008
131. 20080275022 Substituted Quinazolones as Anti-Cancer Agents 11-06-2008
132. 20080274486 Method of Assaying Fad Synthetase - methods of determining activity of flavin adenine dinucleotide synthetase 11-06-2008
133. 20080269500 Process for the Preparation of 4-Aminopyrazole Derivatives 10-30-2008
134. 20080269294 Benzamide Compounds Useful as Histone Deacetylase Inhibitors 10-30-2008
135. 20080269266 NOVEL COMPOUNDS 747 - There is provided novel pyrimidine derivatives of formula or pharmaceutically acceptable salts thereof 10-30-2008
136. 20080269214 Pyrrole Derivatives as Dna Gyrase and Topoisomerase Inhibitors 10-30-2008
137. 20080267914 Chemical Compounds - Compounds of formula are found to be active in inhibiting replication of flaviviridae viruses , wherein R 10-30-2008
138. 20080262811 Crystal Structure of Haemophilus Influenzae Nad Dependent Dna Ligase and Uses Thereof 10-23-2008
139. 20080261240 METHOD - for attenuating a microorganism which comprises inhibiting in the microorganism a metabolic pathway essential for viability 10-23-2008
140. 20080255183 N-[HETEROARYLCARBONYL]-3-THIENYL-L-ALANINE DERIVATIVES AS a5beta1 ANTAGONISTS 10-16-2008
141. 20080255105 Biphenyl Derivatives and Their Use in Treating Hepatitis C 10-16-2008
142. 20080248077 Formulation - slow release anastrozole formulations more particularly to biodegradable polymers 10-09-2008
143. 20080248048 Interleukin-13 Antibody Composition - pharmaceutical composition comprising an interleukin-13 antibody more particularly a monoclonal interleukin-13 10-09-2008
144. 20080242663 NOVEL PYRIMIDINE DERIVATIVES 698 - The invention concerns compounds of Formula I, or a pharmaceutically acceptable salt thereof, where R 10-02-2008
145. 20080221124 Ethanolamine Salt of N- (3-Methoxy-5-Methylpyrazin-2Yl) -2- (4-[1, 3, 4-Oxadiazole-2-Yl] Phenyl) Pyridine-3-Sulphonamide 09-11-2008
146. 20080207616 Quinoxalines as B Baf Inhhibitors - chemical compounds of the formula or pharmaceutically acceptable salts thereof 08-28-2008
147. 20080206303 Prolonged Release Formulations Comprising Anastrozole 08-28-2008
148. 20080200649 Method - for optimised refolding of a protein which method comprises selecting for the protein at least three control factors which affect refolding of 08-21-2008
149. 20080199481 COMPOUNDS - binding members, especially antibody molecules, for CXCL13 08-21-2008