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MERCK AND CO., INC

RAHWAY, NJ US

1. 20100099923 Process for the Preparation of Bicyclo[3.1.0]Hexanols 04-22-2010
2. 20100099750 RNA INTERFERENCE MEDIATED INHIBITION OF MUSCARINIC COLINERGIC RECEPTOR GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) 04-22-2010
3. 20100099744 RNA INTERFERENCE MEDIATED INHIBITION OF MATRIX METALLOPROTEINASE 13 (MMP13) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) 04-22-2010
4. 20100099743 RNA INTERFERENCE MEDIATED INHIBITION OF CHECKPOINT KINASE-1 (CHK-1) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) 04-22-2010
5. 20100099716 CETP INHIBITORS - Compounds having the structures of Formula I including pharmaceutically acceptable salts of the compounds 04-22-2010
6. 20100099695 HCV NS3 Protease Inhibitors - macrocyclic compounds of formula that are useful as inhibitors of the hepatitis C virus NS3 protease 04-22-2010
7. 20100099673 DECAHYDROQUINOLINE ANALOGS AS CB2 RECEPTOR MODULATORS, USEFUL IN THE TREATMENT OF PAIN, RESPIRATORY AND NON-RESPIRATORY DISEASES 04-22-2010
8. 20100093811 HIV PROTEASE INHIBITORS - Compounds of Formula I are disclosed: , wherein X 04-15-2010
9. 20100093779 HCV NS3 PROTEASE INHIBITORS - macrocyclic compounds of formula that are useful as inhibitors of the hepatitis C virus NS3 protease 04-15-2010
10. 20100093759 BICYCLIC ANILIDE HETEROCYCLIC CGRP RECEPTOR ANTAGONISTS 04-15-2010
11. 20100093665 SILYLATED PIPERIDINE DERIVATIVES - Compounds of formula I: I wherein at least one of R4 and R5 comprises Si3 as a substituent selectively attenuate 04-15-2010
12. 20100092505 Method for Shielding Functional Sites or Epitopes on Proteins 04-15-2010
13. 20100087446 2-SUBSTITUTED INDOLE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS 04-08-2010
14. 20100087419 HIV INTEGRASE INHIBITORS - Compounds of Formula I are inhibitors of HIV integrase and inhibitors of HIV replication: STR00001 wherein X 04-08-2010
15. 20100087360 Heterocycle-substituted benzimidazole derivative 04-08-2010
16. 20100081696 FLUORO SUBSTITUTED CYCLOALKANOINDOLES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT 04-01-2010
17. 20100081643 NOVEL CYCLIC BENZIMIDAZOLE DERIVATIVES USEFUL AS ANTI-DIABETIC AGENTS 04-01-2010
18. 20100081642 CB-1 RECEPTOR MODULATOR PHARMACEUTICAL FORMULATIONS 04-01-2010
19. 20100076059 METHOD OF EVALUATING COMPOUND EFFICACIOUS IN TREATING OBESITY BY USING Slc25a10 03-25-2010
20. 20100076046 Antiviral Indoles - Compounds of the formula wherein A, B, D, M, Ar, W, X, Y, Z and R 03-25-2010
21. 20100076004 BICYCLIC SPIROPIPERIDINE BETA-SECRETASE INHIBITORS FOR THE TREATMENT OF ALZHEIMER'S DISEASE 03-25-2010
22. 20100076002 Method of Treating Atherosclerosis, Dyslipidemias and Related Conditions and Pharmaceutical Compositions 03-25-2010
23. 20100075987 ACYL BIPIPERIDINYL COMPOUNDS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT 03-25-2010
24. 20100075970 INHIBITORS OF AKT ACTIVITY - compounds which contain substituted pyridazines and pyrimidines moieties which inhibit the activity of Akt 03-25-2010
25. 20100075907 NEUROMEDIN U RECEPTOR AGONISTS AND USES THEREOF 03-25-2010
26. 20100074888 ANIMAL HAVING MODIFICATION IN MGAT2 GENE 03-25-2010
27. 20100069452 MINERALOCORTICOID RECEPTOR MODULATORS - diphenylmethyl imidazole mineralocorticoid receptor modulators compounds having the structure STR00001 and their 03-18-2010
28. 20100069419 SPIROPIPERIDINE BETA-SECRETASE INHIBITORS FOR THE TREATMENT OF ALZHEIMER'S DISEASE 03-18-2010
29. 20100069359 CONSTRAINED SPIROCYCLIC COMPOUNDS AS CGRP RECEPTOR ANTAGONISTS 03-18-2010
30. 20100069347 HETEROCYCLYL-SUBSTITUTED ANTI-HYPERCHOLESTEROLEMIC COMPOUNDS 03-18-2010
31. 20100063308 LIPID NANOPARTICLE BASED COMPOSITIONS AND METHODS FOR THE DELIVERY OF BIOLOGICALLY ACTIVE MOLECULES 03-11-2010
32. 20100063091 RENIN INHIBITORS - disubstituted piperidinyl renin inhibitor compounds having the structure and their use in treating cardiovascular events and renal 03-11-2010
33. 20100063056 BIPYRIDINE CARBOXAMIDE OREXIN RECEPTOR ANTAGONISTS 03-11-2010
34. 20100063032 SUBSTITUTED PYRIDO[2,3-D]PYRIMIDINE DERIVATIVES AS CANNABINOID-1 RECEPTOR MODULATORS 03-11-2010
35. 20100063024 Dihydropyrazolopyrimidinone Derivatives - compounds of a general formula : STR00001 wherein Ar 03-11-2010
36. 20100063013 CATHEPSIN CYSTEINE PROTEASE INHIBITORS - novel compounds of the formula , wherein R'-R7, X, Y, D and n are as defined in the specification 03-11-2010
37. 20100062523 Expression of Class 2 Mannosidase and Class III Mannosidase in Lower Eukaryotic Cells 03-11-2010
38. 20100062516 Expression of Class 2 Mannosidase and Class III Mannosidase in Lower Eukaryotic Cells 03-11-2010
39. 20100056597 INDOLEDIONE DERIVATIVE - compound represented by the general formula : STR00001 [wherein R1a and R2a each means hydrogen, lower cycloalkyl, lower alkyl, 03-04-2010
40. 20100056580 NOVEL CRYSTALLINE SALT FORM OF AN ANTIDIABETIC COMPOUND 03-04-2010
41. 20100056563 NOVEL 1.8-NAPHTHYRIDINE COMPOUNDS - naphthyridine compounds useful as HIF prolyl hydroxylase inhibitors to treat anemia and like conditions 03-04-2010
42. 20100056550 TRICYCLIC HETEROAROMATIC COMPOUNDS AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES 03-04-2010
43. 20100056516 1-HYDROXY NAPHTHYRIDINE COMPOUNDS AS ANTI-HIV AGENTS 03-04-2010
44. 20100056498 SUBSTITUTED MONOCYCLIC CGRP RECEPTOR ANTAGONISTS 03-04-2010
45. 20100048888 Lipid Nanoparticle Based Compositions and Methods for the Delivery of Biologically Active Molecules 02-25-2010
46. 20100048717 CATHEPSIN B INHIBITORS - Compounds of formula : are found to be selective inhibitors of cathepsin B, and hence useful in treating a variety of 02-25-2010
47. 20100048623 PIPERIDINES AND RELATED COMPOUNDS FOR THE TREATMENT OF ALZHEIMER'S DISEASE 02-25-2010
48. 20100048600 NOVEL BENZIMIDAZOLE DERIVATIVES - compound of the formula : STR00001 02-25-2010
49. 20100048555 IMIDAZOTHIAZOLE DERIVATIVES AS MARK INHIBITORS 02-25-2010
50. 20100048551 Tricyclic Compounds Useful as Inhibitors of Kinases 02-25-2010
51. 20100041893 FORMATION OF TETRA-SUBSTITUTED ENAMIDES AND STEREOSELECTIVE REDUCTION THEREOF 02-18-2010
52. 20100041724 Process For Synthesizing A CETP Inhibitor 02-18-2010
53. 20100041680 PIPERIDINE DERIVATIVES - Compounds of formula I: I selectively inhibit production of Ab and hence find use in treatment of Alzheimer's disease and other 02-18-2010
54. 20100041667 Piperidine and pyrrolidine beta-secretase inhibitors for the treatment of alzheimer's disease 02-18-2010
55. 20100041660 NOVEL 2-PYRIDINECARBOXAMIDE DERIVATIVES - compound which has a glucokinase-activating effect and is useful as a therapeutic agent for diabetes mellitus 02-18-2010
56. 20100041652 TYROSINE KINASE INHIBITORS - compounds that are capable of inhibiting modulating and/or regulating signal transduction of both receptor-type and 02-18-2010
57. 20100041102 ANTAGONISTS OF PCSK9 - Antagonists of human proprotein convertase subtilisin-kexin type 9 are disclosed 02-18-2010
58. 20100041097 Synthetic gene control region - which comprises a gene regulatory sequence comprising a binding site for a gene regulatory protein of a yeast strain 02-18-2010
59. 20100041026 Method for Identiflying Modulators of Rufy2 Useful for Treating Alzheimer's Disease 02-18-2010
60. 20100040611 ANTAGONISTS OF PCSK9 - Antagonists of human proprotein convertase subtilisin-kexin type 9 are disclosed 02-18-2010
61. 20100040610 ANTAGONISTS OF PCSK9 - Antagonists of human proprotein convertase subtilisin-kexin type 9 are disclosed 02-18-2010
62. 20100036135 Process for Making Hydroisoindoline Tachykinin Receptor Antagonists 02-11-2010
63. 20100035991 AMIDE BASE SALTS OF SAHA AND POLYMORPHIS THEREOF 02-11-2010
64. 20100035931 TRIPYRIDYL CARBOXAMIDE OREXIN RECEPTOR ANTAGONISTS 02-11-2010
65. 20100035857 ANTI-HYPERCHOLESTEROLEMIC COMPOUNDS - This invention provides cholesterol absorption inhibitors of Formula I:I and the pharmaceutically acceptable salts 02-11-2010
66. 20100035835 NUCLEOSIDE ARYL PHOSPHORAMIDATES FOR THE TREATMENT OF RNA-DEPENDENT RNA VIRAL INFECTION 02-11-2010
67. 20100035818 OPTIMIZED EXPRESSION OF HPV 52 L1 IN YEAST 02-11-2010
68. 20100029736 2-SUBSTITUTED PROLINE BIS-AMIDE OREXIN RECEPTOR ANTAGONISTS 02-04-2010
69. 20100029726 CYCLOHEXANESULFONYL DERIVATIVES AS GLYT1 INHIBITORS TO TREAT SCHIZOPHRENIA 02-04-2010
70. 20100029701 MACROCYCLIC SPIROPIPERIDINE BETA-SECRETASE INHIBITORS FOR THE TREATMENT OF ALZHEIMER'S DISEASE 02-04-2010
71. 20100029697 SUBSTITUTED PYRIDO[3,2-E][1,2,4]TRIAZOLO[4,3-C]PYRIMIDINE DERIVATIVES AS CANNABINOID-1 RECEPTOR MODULATORS 02-04-2010
72. 20100029688 BIPIPERIDINYL COMPOUNDS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT 02-04-2010
73. 20100029678 DIURETICS - compound having the structure STR00001 wherein X is selected from the group consisting of: a bond, --NHCH 02-04-2010
74. 20100029666 Macrocyclic Quinoxaline Compounds as HCV NS3 Protease Inhibitors 02-04-2010
75. 20100029012 Method for identifying modulators of the NRF2-KEAP1-AREP pathway 02-04-2010
76. 20100028951 PRODUCTION OF GLYCOPROTEINS WITH MODIFIED FUCOSYLATION 02-04-2010
77. 20100028333 RECEPTOR FOR AMYLOID BETA AND USES THEREOF 02-04-2010
78. 20100022771 REACTION APPARATUS, AND REACTION METHOD - The present invention is directed at obtaining a high yield of a target substance and simultaneously securing 01-28-2010
79. 20100022630 Method of treatment using fatty acid synthesis inhibitors 01-28-2010
80. 20100022598 Substituted inmidazoles as bombesin receptor subtype-3 modulators 01-28-2010
81. 20100022573 INHIBITORS OF AKT ACTIVITY - The instant invention provides for substituted naphthyridine compounds that inhibit Akt activity 01-28-2010
82. 20100022477 FUSED AROMATIC PTP-1B INHIBITORS - The invention encompasses the novel class of compounds represented by the formula below, which are inhibitors of the 01-28-2010
83. 20100022468 NUCLEOSIDE CYCLIC PHOSPHORAMIDATES FOR THE TREATMENT OF RNA-DEPENDENT RNA VIRAL INFECTION 01-28-2010
84. 20100022404 Gene/protein marker for prediction or diagnosis of pharmacological efficacy of aurora a inhibitor 01-28-2010
85. 20100021991 Methods for Producing Modified Glycoproteins 01-28-2010
86. 20100017894 Mutants of Human App and Their Use for the Production of Transgenice Animals 01-21-2010
87. 20100016561 N-Acetylglucosaminyltransferase III Expression in Lower Eukaryotes 01-21-2010
88. 20100016555 N-Acetylglucosaminyltransferase III Expression in Lower Eukaryotes 01-21-2010
89. 20100016335 NOVEL AMINOPYRIDINE DERIVATIVES HAVING AURORA A SELECTIVE INHIBITORY ACTION 01-21-2010
90. 20100016308 Tetrahydroindole Derivatives for Treatment of Alzheimer's Disease 01-21-2010
91. 20100015218 COMPOSITIONS AND METHODS FOR POTENTIATED ACTIVITY OF BIOLOGICALLY ACTIVE MOLECULES 01-21-2010
92. 20100010041 DIFLUORINATED PIPERIDINES FOR TREATMENT OF ALZHEIMER'S DISEASE AND RELATED CONDITIONS 01-14-2010
93. 20100009987 AMINOTHIAZOLE DERIVATIVES AS INHIBITORS OF MARK 01-14-2010
94. 20100009967 SOLID DOSAGE FORMULATIONS OF TELCAGEPANT POTASSIUM 01-14-2010
95. 20100009962 Benzyl-substituted quinolone m1 receptor positive allosteric modulators 01-14-2010
96. 20100009959 Pentacyclic Indole Derivatives as Antiviral Agents 01-14-2010
97. 20100009957 NOVEL INHIBITORS OF BETA-LACTAMASE - class of 7-oxo-2,6-diazabicyclo-[3 01-14-2010
98. 20100009866 Surface Display of Whole Antibodies in Eukaryotes 01-14-2010
99. 20100009461 Npcil1 (Npc3) And Methods Of Identifying Ligands Thereof 01-14-2010
100. 20100004287 Cyclic Derivatives as Inhibitors of Stearoyl-Coenzyme a Delta-9 Desaturase 01-07-2010
101. 20100004280 Substituted imidazoles as bombesin receptor subtype-3 modulators 01-07-2010
102. 20100004245 AZACYCLOALKANE DERIVATIVES AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE 01-07-2010
103. 20100004229 Potassium Channel Inhibitors - pyridin-3-yl pyridin-3-amine compounds and derivatives thereof having the structure formula useful as potassium channel 01-07-2010
104. 20100004184 Anti-hypercholesterolemic compounds - This invention provides cholesterol absorption inhibitors of Formula , and the pharmaceutically acceptable salts 01-07-2010
105. 20100004158 GLUCAGON RECEPTOR ANTAGONIST COMPOUNDS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE 01-07-2010
106. 20100003665 Real-time HPV PCR Assays - fluorescent multiplex PCR assay for detecting the presence of an HPV type in a sample using multiple fluorophores to 01-07-2010
107. 20100003276 Methods for treating anthrax and inhibiting lethal factor 01-07-2010
108. 20090325991 Spirolactam Bicyclic CGRP Receptor Antagonists 12-31-2009
109. 20090325990 ACYLATED SPIROPIPERIDINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR MODULATORS 12-31-2009
110. 20090325953 P38 KINASE INHIBITING AGENTS - Compounds described by the chemical formula or pharmaceutically acceptable salts thereof: STR00001 are inhibitors of p38 12-31-2009
111. 20090325936 IMIDAZOPYRIDINE ANALOGS AS CB2 RECEPTOR MODULATORS, USEFUL IN THE TREATMENT OF PAIN, RESPIRATORY AND NON-RESPIRATORY DISEASES 12-31-2009
112. 20090325862 Histone Deacetylase Inhibitors for the Treatment of Neurodegeneration 12-31-2009
113. 20090318560 FORMULATIONS FOR CATHEPSIN K INHIBITORS - The instant invention relates to pharmaceutical compositions comprising cathepsin K inhibitors as the active 12-24-2009
114. 20090318541 Benzothiophene hydroxamic acid derivatives with carbamate, urea, amide and sulfonamide substitutions 12-24-2009
115. 20090318518 INDOLE AND INDOLINE CYCLOPROPYL AMIDE DERIVATIVES AS EP4 RECEPTOR ANTAGONISTS 12-24-2009
116. 20090318476 Azacycloalkane Derivatives as Inhibitors of Stearoyl-Coenzyme a Delta-9 Desaturase 12-24-2009
117. 20090317850 Crystal Structure of Human 70KD Ribosomal Protein S6 Kinase 1 Kinase Domain 12-24-2009
118. 20090317840 AUTOMATED DETERMINATION OF CHLAMYDIA INFECTION-FORMING UNITS 12-24-2009
119. 20090312335 Hiv Integrase Inhibitors - Substituted hydroxytetrahydropyrrolopyrazinone and substituted hydroxytetrahydro-pyrazolopyrazinone compounds of Formula are 12-17-2009
120. 20090312303 Antidiabetic Bicyclic Compounds - Bicyclic compounds containing a phenyl or pyridyl ring fused to a cycloalkyl or heterocyclic ring to which is attached 12-17-2009
121. 20090312241 Macrocyclic Compounds as Antiviral Agents 12-17-2009
122. 20090306375 Process for production of 4(3H)-quinazolinone derivative 12-10-2009
123. 20090306202 D-homoandrosta-17-yl carbamate derivatives as selective glucocorticoid receptor ligands 12-10-2009
124. 20090306169 Use of Fused Pyrrole Carboxylic Acids for the Treatment of Neurodegenerative and Psychiatric Diseases and D-Amino Acid Oxidase Inhibitors 12-10-2009
125. 20090306115 Phenyl ethyne compounds - In accordance with the present invention, there is provided a novel class of heterocyclic compounds 12-10-2009
126. 20090306076 Morpholine Carboxamide Prokineticin Receptor Antagonists 12-10-2009
127. 20090306071 Inhibitors of Janus Kinases - The instant invention provides for compounds that inhibit the four known mammalian JAK kinases and PDK1 12-10-2009
128. 20090306058 Sulphone Derivatives for Treatment of Cancer 12-10-2009
129. 20090306037 Combination of a Dipeptidyl Peptidase-IV Inhibitor and a Cannabinoid CB1 Receptor Antagonist for the Treatment of Diabetes and Obesity 12-10-2009
130. 20090305314 Upregulation of Adamts4 Protease Activity for the Treatment of Alzheimer's Disease 12-10-2009
131. 20090304594 Methods for Predicting Treatment Response Based On the Expression Profiles of Protein and Transcription Biomarkers 12-10-2009
132. 20090298949 AMINOALKYLPHENOLS, METHODS OF USING AND MAKING THE SAME 12-03-2009
133. 20090298856 2,3 Substituted fused bicyclic pyrimidin-4(3H)-ones modulating the function of the vanilliod-1receptor (VR1) 12-03-2009
134. 20090298073 Kidney Toxicity Biomarkers - Novel biomarkers for kidney toxicity 12-03-2009
135. 20090298046 Assays for Histone Deacetylase 1/2 Selective Inhibitors 12-03-2009
136. 20090291988 Reversible Inhibitors of Monoamine Oxidase A and B 11-26-2009
137. 20090291965 Histone Deacetylase Inhibitors With Aryl-Pyrazolyl-Motifs 11-26-2009
138. 20090291955 Azacyclohexane Derivatives as Inhibitors of Stearoyl-Coenzyme a Delta-9 Desaturase 11-26-2009
139. 20090291941 Tyrosine Kinase Inhibitors - pyrido[3 2-c]benzazocinone derivatives and related compounds that are useful for treating cellular proliferative diseases 11-26-2009
140. 20090286825 Indole derivatives as crth2 receptor antagonists 11-19-2009
141. 20090286777 5,6,Fused Pyrrolidine Compounds Useful as Tachykinin Receptor Antagonists 11-19-2009
142. 20090286772 2-(Phenyl or Heterocyclic)-1H-Phenanthro[9,10-D]Imidazoles 11-19-2009
143. 20090286765 Therapeutic Agents - compound of the formula : wherein R 11-19-2009
144. 20090282913 METHOD AND APPARATUS FOR MEASURING THE VOLUME OF AN ANIMAL PAW 11-19-2009
145. 20090281306 Process for the Preparation of Cgrp Antagonist 11-12-2009
146. 20090281154 Ophthalmic Compositions for Treating Ocular Hypertension 11-12-2009
147. 20090281117 Substituted Imidazole-4-Carboxamides as Cholecystokinin -1 Receptor Modulators 11-12-2009
148. 20090281103 Renin Inhibitors - novel renin inhibitors of the general Formula and their use as active ingredients in the preparation of pharmaceutical compositions 11-12-2009
149. 20090281080 Spirohydantoin Tricyclic CGRP Receptor Antagonists 11-12-2009
150. 20090275619 Amide Substituted Indazole and Benzotriazole Derivatives as Poly(ADP-Ribose)Polymerase (PARP) Inhibitors 11-05-2009
151. 20090275617 Aryl-Substituted Nitrogen-Containing Heterocyclic Compounds 11-05-2009
152. 20090275550 Pyridyl Amide T-Type Calcium Channel Antagonists 11-05-2009
153. 20090275515 2-HYDROXY-2-PHENYLTHIOPHENYLPROPIONAMIDES AS ANDROGEN RECEPTOR MODULATORS 11-05-2009
154. 20090270511 PRODRUGS OF INHIBITORS OF CATHEPSIN S - compounds of formula which are prodrugs of inhibitors of cathepsin S and as such are useful in the prevention 10-29-2009
155. 20090270477 POLYMORPHS OF A HYDROISOINDOLINE TACHYKININ RECEPTOR ANTAGONIST 10-29-2009
156. 20090270467 Aminocyclohexanes as Dipeptidyl Peptidase-IV Inhibitors for the Treatment or Prevention of Diabetes 10-29-2009
157. 20090270451 Piperdine Glycine Transporter Inhibitors 10-29-2009
158. 20090270436 SPIROCHROMANON DERIVATIVES - compound of a general formula : wherein Ar1 represents a group formed from an aromatic ring selected from a group 10-29-2009
159. 20090270434 AZACYCLOALKANE DERIVATIVES AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE 10-29-2009
160. 20090270406 Combination Therapy for the Treatment of Urinary Frequency, Urinary Urgency and Urinary Incontinence 10-29-2009
161. 20090270395 EP4 Receptor Agonist, Compositions and Methods Thereof 10-29-2009
162. 20090270351 PHOSPHORUS DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS 10-29-2009
163. 20090269278 Radiolabeled Glycine Trasporter Inhibitors 10-29-2009
164. 20090264622 Rhesus monkey Nur77 - The Macaca mulatta Nur77 nuclear receptor and the nucleic acid encoding the rhNur77 nuclear receptor are described 10-22-2009
165. 20090264479 Papain Family Cysteine Protease Inhibitors for the Treatment of Parasitic Diseases 10-22-2009
166. 20090264476 CB-1 receptor modulator formulations - Described herein are solid stable pharmaceutical formulations of cannabinoid receptor inverse agonists 10-22-2009
167. 20090264473 Novel Crystalline Forms of Antidiabetic Compounds 10-22-2009
168. 20090264436 CB-1 receptor modulator formulations - Described herein are solid stable pharmaceutical formulations of cannabinoid receptor inverse agonists 10-22-2009
169. 20090264426 Bicyclic aromatic substituted pyridone derivative 10-22-2009
170. 20090264405 Cetp Inhibitors - Compounds of Formula I including pharmaceutically acceptable salts of the compounds are CETP inhibitors 10-22-2009
171. 20090258918 EP4 receptor agonist, compositions and methods thereof 10-15-2009
172. 20090258913 Triazole Derivatives as Inhibitors of 11-Beta-Hydroxysteroid Dehydrogenase-1 10-15-2009
173. 20090258903 Aminoethane Sulfonamide Orexin Receptor Antagonists 10-15-2009
174. 20090258894 Fused Aminopiperidines as Dipeptidyl Peptidase-IV Inhibitors for the Treatment or Prevention of Diabetes 10-15-2009
175. 20090258891 Macrocyclic Compounds As Antiviral Agents 10-15-2009
176. 20090258885 Diphenylmethane Derivatives as Inhibitors of Leukotriene Biosynthesis 10-15-2009
177. 20090258884 Substituted amides - Novel compounds of the structural formula are antagonists and/or inverse agonists of the Cannabinoid-1 receptor and are useful in 10-15-2009
178. 20090258871 Aza-Substituted Spiro Derivatives - compound of the following formula or its pharmaceutically-acceptable salt is provided: STR00001 [wherein X 10-15-2009
179. 20090258862 Niacin receptor agonists, compositions containing such compounds and methods of treatment 10-15-2009
180. 20090258853 Somatostatin Agonists - This invention relates to compounds which are agonists of somatostatin and selective toward somatostatin receptor subtype SSTR2 10-15-2009
181. 20090258852 Inhibitors of Checkpoint Kinases - The instant invention provides for compounds which comprise benzoisoquinolinones and aza derivatives that inhibit 10-15-2009
182. 20090258851 DIARYL SUBSTITUTED ALKANES - The instant invention provides compounds of Formula II which are 5-lipoxygenase activating protein inhibitors 10-15-2009
183. 20090253769 Inhibitors of mammalian hdac 11 useful for treating hdac 11 mediated disorders 10-08-2009
184. 20090253756 Indole Amide Derivatives as EP4 Receptor Antagonists 10-08-2009
185. 20090253744 Acylated piperidine derivatives as melanocortin-4 receptor modulators 10-08-2009
186. 20090253734 INHIBITORS OF AKT ACTIVITY - The instant invention provides for substituted naphthyridine compounds that inhibit Akt activity 10-08-2009
187. 20090253705 HYDROXYMETHYL PYRROLIDINES AS BETA 3 ADRENERGIC RECEPTOR AGONISTS 10-08-2009
188. 20090253681 HIV Integrase Inhibitors - Compounds of Formula I are inhibitors of FHV integrase and inhibitors of FHV replication , wherein m, n, X, R 10-08-2009
189. 20090253673 Substituted Pyrazoles as Ghrelin Receptor Antagonists 10-08-2009
190. 20090253672 Cathepsin Cysteine Protease Inhibitors - This invention relates to a novel class of compounds represented by the formula below wherein the meanings of 10-08-2009
191. 20090253665 METHOD OF TREATMENT OF DISEASE USING AN ADENOSINE A1 RECEPTOR ANTAGONIST AND AN ALDOSTERONE INHIBITOR 10-08-2009
192. 20090247770 PROCESS FOR MAKING LACTAM TACHYKININ RECEPTOR ANTAGONISTS 10-01-2009
193. 20090247596 THIOPHENECARBOXAMIDE DERIVATIVES AS EP4 RECEPTOR LIGANDS 10-01-2009
194. 20090247565 Tyrosine Kinase Inhibitors - imidazo[1 2-a]pyrimidine derivatives that are useful for treating cellular proliferative diseases 10-01-2009
195. 20090247560 Diaryl ketimine derivative - Provided is a compound of a formula : STR00001 [wherein R 10-01-2009
196. 20090247549 Methods of using saha and bortezomib for treating cancer 10-01-2009
197. 20090247514 Spirolactam aryl cgrp receptor antagonists 10-01-2009
198. 20090247504 Indazole Derivatives for Treatment of Alzheimer's Disease 10-01-2009
199. 20090247499 SULFONYLATED PIPERAZINES AS CANNABINOID-1 RECEPTOR MODULATORS 10-01-2009
200. 20090247460 Inhibitor of vascular endothelial cell growth factor 10-01-2009
201. 20090246192 1D05 PCSK9 antagonists - Antagonists of human proprotein convertase subtilisin-kexin type 9 are disclosed 10-01-2009
202. 20090239946 Pharmaceutical compositions of HDAC inhibitors and chelatable metal compounds, and metal-HDAC inhibitors chelate complexes 09-24-2009
203. 20090239905 PIPERIDINES AND RELATED COMPOUNDS FOR THE TREATMENT OF DEMENTIA 09-24-2009
204. 20090239876 Substituted 4-Hydroxypyrimidine-5-Carboxamides 09-24-2009
205. 20090239870 Spirohydantoin Aryl Cgrp Receptor Antagonists 09-24-2009
206. 20090239862 Substituted Imidazole 4-Carboxamides as Cholecystokinin-1 Receptor Modulators 09-24-2009
207. 20090239849 Aryl-Fused Spirocyclic Compounds - novel class of aryl-fused spirocyclic compounds 09-24-2009
208. 20090239843 Bridged diazepan orexin receptor antagonists 09-24-2009
209. 20090233992 HEPATITIS C VIRUS VACCINE - The present invention features Ad6 vectors and a nucleic acid encoding a Met-NS3-NS4A-NS4B-NS5A-NS5B polypeptide containing 09-17-2009
210. 20090233936 Fused Aminopiperidines as Dipeptidyl Peptidase-4 Inhibitors for the Treatment or Prevention of Diabetes 09-17-2009
211. 20090233896 Inhibitors of checkpoint kinases - The instant invention provides for compounds which comprise substituted pyridyl aminothiazoles that inhibit CHK1 09-17-2009
212. 20090232795 1B20 PCSK9 ANTAGONISTS - Antagonists of human proprotein convertase subtilisin-kexin type 9 are disclosed 09-17-2009
213. 20090221679 Novel HIV Targets - Using a method to measure the effect of downregulation of certain cellular proteins on HIV integration 09-03-2009
214. 20090221669 Disubstituted Aniline Compounds - novel class of disubstituted aniline compounds 09-03-2009
215. 20090221611 Fused Triazole Tachykinin Receptor Antagonists 09-03-2009
216. 20090221592 Dodecylsulfate Salt Of A Dipeptidyl Peptidase-Iv Inhibitor 09-03-2009
217. 20090221571 HIV INTEGRASE INHIBITORS - Pyridopyrimidine carboxamide compounds of Formula I are inhibitors of HIV integrase and inhibitors of HIV replication: 09-03-2009
218. 20090221535 IMMUNOGENIC COMPOSITIONS FOR GRAM POSITIVE BACTERIA SUCH AS STREPTOCOCCUS AGALACTIAE 09-03-2009
219. 20090215825 SUBSTITUTED PYRAZOLES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE 08-27-2009
220. 20090215775 Sulphonamido-Substituted Cyclohexyl Sulphones for Treatment of Cancer 08-27-2009
221. 20090215101 HCV Protease substrates - The present invention features HCV NS3 protease substrates containing a europium label and a quenching group 08-27-2009
222. 20090209571 Phenanthrene derivatives as MPGES-1 inhibitors 08-20-2009
223. 20090209566 Spirocyclic Compounds - novel class of substituted spirocyclic compounds represented by the following structural Formula: I Wherein A 08-20-2009
224. 20090209564 Glucagon Receptor Antagonist Compounds, Compositions Containing Such Compounds And Methods Of Use 08-20-2009
225. 20090209562 Fused ring 4-oxopyrimidine derivative - compound represented by formula below or a pharmaceutically acceptable salt thereof 08-20-2009
226. 20090209556 SOLUBLE GUANYLATE CYCLASE ACTIVATORS - compound having the structure STR00001 useful for treatment or prevention of cardiovascular diseases 08-20-2009
227. 20090209544 Aminotetrahydropyrans as Dipeptidyl Peptidase-IV Inhibitors for the Treatment or Prevention of Diabetes 08-20-2009
228. 20090209523 Pyrrolo[1,2-A] Pyrazin-1(2H)-One and Pyrrolo[1,2-D][1,2,4]Triazin-1(2H)-One Derivatives as Inhibitors of Poly(Adp-Ribose)Polymerase (Parp) 08-20-2009
229. 20090209024 Combinatorial DNA library for producing modified N-glycans in lower eukaryotes 08-20-2009
230. 20090203922 Process for Synthesizing 2-Phenyl-1H-Phenanthro[9,10-d]Imidazole Derivative 08-13-2009
231. 20090203903 Thiazolyl mglur5 antagonists and methods for their use 08-13-2009
232. 20090203710 Novel piperidine derivative - Provided are a histamine-H3 receptor antagonist 08-13-2009
233. 20090203684 Tyrosine kinase inhibitors - 5H-benzo[4 5]cyclohepta[1 2-b]pyridine derivatives of formula that are useful for treating cellular proliferative diseases 08-13-2009
234. 20090203105 URA5 gene and methods for stable genetic integration in yeast 08-13-2009
235. 20090203008 Rapid method to determine inhibitor sensitivity of NS3/4A protease sequences cloned from clinical samples 08-13-2009
236. 20090202987 Canis sphingosine 1-phosphate receptor isoform 2 08-13-2009
237. 20090197908 Benzocycloheptapyridines as inhibitors of the receptor tyrosine kinase met 08-06-2009
238. 20090197904 Sulphamides for Treatment of Cancer - Bridged bicyclic sulphamides of formula are disclosed for treatment of cancer 08-06-2009
239. 20090197900 METHODS OF TREATING HEART FAILURE AND RENAL DYSFUNCTION IN INDIVIDUALS WITH AN ADENOSINE A1 RECEPTOR ANTAGONIST 08-06-2009
240. 20090197883 Diphenyl Substituted Cycloalkanes, Compositions Containing Such Compounds and Methods Of Use 08-06-2009
241. 20090197299 Method for Assessing Airborn Microorganisms 08-06-2009
242. 20090192174 Novel Aminopyridine Derivatives Having Aurora a Selective Inhibitory Action 07-30-2009
243. 20090192158 Methods for Treating or Preventing Neoplasias 07-30-2009
244. 20090192155 Identification of Compounds Suitable for Treating Ad 07-30-2009
245. 20090192143 Substituted diazepan orexin receptor antagonists 07-30-2009
246. 20090192139 CGRP RECEPTOR ANTAGONISTS - compounds of Formula I: STR00001 and Formula II: STR00002 useful as antagonists of CGRP receptors and useful in the 07-30-2009
247. 20090191578 Canis sphingosine 1-phosphate receptor isoform 5 07-30-2009
248. 20090191552 Novel Human Acidic Mammalian Chitinase and Use Thereof 07-30-2009
249. 20090187028 Process for preparing Chiral Dipeptidyl Peptidase -IV Inhibitor Intermediates 07-23-2009
250. 20090186928 Novel crystalline forms of an inhibitor of 11-beta-hydroxysteroid dehydrogenase type 1 07-23-2009
251. 20090186926 Self-Emulsifying Formulations of CETP Inhibitors 07-23-2009
252. 20090186919 PIPERIDINE DERIVATIVES FOR TREATMENT OF ALZHEIMER'S DISEASE 07-23-2009
253. 20090186871 Tyrosine kinase inhibitors - compounds that are capable of inhibiting modulating and/or regulating signal transduction of both receptor-type and 07-23-2009
254. 20090182021 Tricyclic Beta-Secretase Inhibitors for the Treatment of Alzheimer's Disease 07-16-2009
255. 20090182002 Tyrosine kinase inhibitors - This invention relates to salt forms of the compound N-[-1 4-dioxan-2-ylmethyl]-N-methyl-N'-[3--- 5-oxo-5H-benzo[4 07-16-2009
256. 20090182001 Inhibitors of checkpoint kinases - The instant invention provides for compounds which comprise fused imidazoles that inhibit CHK1 activity 07-16-2009
257. 20090181994 TRIAZOLE DERIVATIVES AS INHIBITORS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE-1 07-16-2009
258. 20090181946 Benzaepinones as Sodium Channel Blockers 07-16-2009
259. 20090176986 Process for the Preparation of Pyridine Heterocycle Cgrp Antagonist Intermediate 07-09-2009
260. 20090176861 Cathepsin cysteine protease inhibitors - novel class of compounds mainly substituted leucinamide-carboxylate derivatives of formula wherein X is O or NR 07-09-2009
261. 20090176859 Cathepsin cysteine protease inhibitors - novel class of compounds mainly, leucinamide-amino-carboxylate derivatives of formula wherein Y is CR 07-09-2009
262. 20090176854 PYRAZOLE DERIVATIVES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE 07-09-2009
263. 20090176836 Cyclic Ketal Beta-Secretase Inhibitors for the Treatment of Alzheimer's Disease 07-09-2009
264. 20090176789 Diazaspirodecane orexin receptor antagonists 07-09-2009
265. 20090176765 Pyridinone and Pyridazinone Derivatives as Inhibitors of Poly (Adp-Ribose) Polymerase (Parp) 07-09-2009
266. 20090176757 Bicyclic Spirohydantoin CGRP Receptor Antagonists 07-09-2009
267. 20090176263 Canis sphingosine 1-phosphate receptort isoform 1 07-09-2009
268. 20090176243 Novel monkey GPR103 and monkey QRFP and method of evaluating compound by using GPR103 07-09-2009
269. 20090170891 Niacin Receptor Agonists, Compositions Containing Such Compounds and Methods of Treatment 07-02-2009
270. 20090170863 Acylated Spiropiperidine Derivatives as Melanocortin-4 Receptor Modulators 07-02-2009
271. 20090170830 Tricyclic Beta-Secretase Inhibitors for the Treatment of Alzheimer's Disease 07-02-2009
272. 20090170828 Azetidine Derivatives as Inhibitors of Stearoyl-Coenzyme a Delta-9 Desaturase 07-02-2009
273. 20090170824 Diarylsulfones as 5-HT2A Antagonists - Compounds of formula I: STR00001 are potent and selective antagonists of the human 5-HT 07-02-2009
274. 20090170159 PRODUCTION OF GLYCOPROTEINS WITH REDUCED O-GLYCOSYLATION 07-02-2009
275. 20090163559 Estrogen receptor modulators - compounds and derivatives thereof, their synthesis, and their use as estrogen receptor modulators 06-25-2009
276. 20090163544 Use of NK-3 Receptor Antagonists for the Treatment of Nausea and Vomiting 06-25-2009
277. 20090163379 Eukaryotic cell display systems - expression vectors and helper display vectors which can be used in various combinations as vector sets for display of 06-25-2009
278. 20090162377 Immunoglobulins comprising predominantly a Gal2GlcNAc2Man3GlcNAc2 glycoform 06-25-2009
279. 20090156825 Fluorescent compounds that bind to histone deacetylase 06-18-2009
280. 20090156619 Heterocycle Substituted Amide and Sulfur Amide Derivatives as Histone Deacetylase (HDAC) Inhibitors 06-18-2009
281. 20090156617 Tyrosine kinase inhibitors - imidazo[1 2-a]pyrimidine derivatives that are useful for treating cellular proliferative diseases 06-18-2009
282. 20090156591 Thiophene and Thiazole Substituted trifluoroethanone Derivatives as Histone Deacetylase (Hdac) Inhibitors 06-18-2009
283. 20090156579 Combination of a Dipeptidyl Peptidase-4 Inhibitor and an Anti-Hypertensive Agent for the Treatment of Diabetes and Hypertension 06-18-2009
284. 20090155847 Combinatorial DNA library for producing modified N-glycans in lower eukaryotes 06-18-2009
285. 20090155298 Matrix Metalloproteinase 11 Vaccine - Compositions comprising matrix metalloproteinase 11 or stromelysin-3 or the nucleic acid en-> 06-18-2009
286. 20090149526 Tetracyclic Indole Derivatives as Antiviral Agents 06-11-2009
287. 20090149470 Novel aminopyridine derivatives having aurora a selective inhibitory action 06-11-2009
288. 20090149467 Tyrosine Kinase Inhibitors - pyridinyloxy- and pyrimidinyloxyindole derivatives that are useful for treating cellular proliferative diseases 06-11-2009
289. 20090149398 6,11-3c-bicyclic 8a-azalide derivatives - Compounds of Formula , and pharmaceutically acceptable salts, esters, and prodrugs thereof: are disclosed, 06-11-2009
290. 20090148850 Methods for identifying modulators of P2RY14 06-11-2009
291. 20090143429 Quinoline Derivatives as Neurokinin Receptor Antagonists 06-04-2009
292. 20090143413 Thiazole Derivatives as CXCR3 Receptor Modulators 06-04-2009
293. 20090137587 Phenylpyridone Derivative - compound represented by the formula is contained as an active ingredient: STR00001 wherein R 05-28-2009
294. 20090137576 Novel Piperidine Derivative - substance having an antagonistic effect on the binding of histamine to a histamine H3 receptor or an inhibitory effect on 05-28-2009
295. 20090137548 1,3-Oxazolidin-2-One Derivatives Useful as Cetp Inhibitors 05-28-2009
296. 20090137546 Anti-Hypercholesterolemic Compounds - This invention provides cholesterol absorption inhibitors of Formula I: and the pharmaceutically acceptable salts 05-28-2009
297. 20090137529 SUBSTITUTED ESTERS AS CANNABINOID-1 RECEPTOR MODULATORS 05-28-2009
298. 20090136979 Class IIA Histone Deacetylase (HDAC) Substrate 05-28-2009
299. 20090136570 Taste-Masked Tablets and Granules - Orally administered taste-masked tablets and granules contain a hydroxypyrimidinone carboxamide a 05-28-2009
300. 20090136525 Immunoglobulins Comprising Predominantly a Glcnacman3Glcnac2 Glycoform 05-28-2009
301. 20090136449 Tetracyclic Indole Derivatives as Antiviral Agents 05-28-2009
302. 20090131664 Method for Producing 4(3H)-Quinazolinone Derivative 05-21-2009
303. 20090131494 Non-Nucleoside Reverse Transcriptase Inhibitors 05-21-2009
304. 20090131472 P38 Kinase Inhibiting Agents - Compounds described by the chemical formula or pharmaceutically acceptable salts thereof: are inhibitors of p38 and are 05-21-2009
305. 20090131465 Synthesis and crystalline forms of melanocortin-4 receptor agonist 05-21-2009
306. 20090131464 SPIROCHROMANONE DERIVATIVES AS ACETYL COENZYME A CARBOXYLASE (ACC) INHIBITORS 05-21-2009
307. 20090131451 Diagnosis and treatment of type 2 diabetes and other disorders 05-21-2009
308. 20090131423 Tyrosine Kinase Inhibitors - imidazo[1 2-a]pyrimidine derivatives that are useful for treating cellular proliferative diseases 05-21-2009
309. 20090131419 Sulphones which modulate the action of gamma secretase 05-21-2009
310. 20090130709 Endomannosidases in the modification of glycoproteins in eukaryotes 05-21-2009
311. 20090124799 Process for the preparation of Caprolactam Cgrp Antagonist 05-14-2009
312. 20090124689 CETP Inhibitors - Compounds having a biphenyl group substituted with a phenyl or heteroaromatic group as shown in Formula I 05-14-2009
313. 20090124665 Potassium Channel Inhibitors - compounds having the structure useful as potassium channel inhibitors to treat cardiac arrhythmias, and the like 05-14-2009
314. 20090124661 HCV NS3 PROTEASE INHIBITORS - macrocyclic compounds of formula that are useful as inhibitors of the hepatitis C virus NS3 protease 05-14-2009
315. 20090124648 Synthesis and Crystalline Forms of Npy5 Antagonist 05-14-2009
316. 20090124641 Mitotic Kinesin Inhibitors - fluorinated 2-aminomethylquinazolinone derivatives that are useful for treating cellular proliferative diseases 05-14-2009
317. 20090124603 Diazepan Orexin Receptor Antagonists - diazepan compounds which are antagonists of orexin receptors 05-14-2009
318. 20090124601 Tartaric Acid Salts of a Dipeptidyl Peptidase-IV Inhibitor 05-14-2009
319. 20090124600 N-Alkyl-Azacycloalkyl NMDA/NR2B Antagonists 05-14-2009
320. 20090124000 Recombinant Vectors - Methods and materials are provided for integrating heterologous nucleic acids into the genome of a cell or virus without 05-14-2009
321. 20090123571 Method of treating men with testosterone supplement and 5alpha-reductase inhibitor 05-14-2009
322. 20090123538 Angiotensin II Receptor Antagonists - The compounds of the present invention are polymorphic crystalline forms of the compound 05-14-2009
323. 20090118304 2-HETEROARYL-SUBSTITUTED INDOLE DERIVATIVE 05-07-2009
324. 20090118300 Substituted Imidazole 4-Carboxamides as Cholecystokinin-1 Receptor Modulators 05-07-2009
325. 20090118296 Heteroaromatic Compounds As Inhibitors Of Stearoyl-Coenzyme A Delta-9 Desaturase 05-07-2009
326. 20090118291 Histone deacetylase inhibitors - This invention relates to hydroxamic acid derivatives having a carbamate linkage that are inhibitors of histone 05-07-2009
327. 20090118223 Novel 2'-c-methyl and 4'c-methyl nucleoside derivatives 05-07-2009
328. 20090118200 Proline bis-amide orexin receptor antagonists 05-07-2009
329. 20090117616 Methods for reducing or eliminating alpha-mannosidase resistant glycans for the production of glycoproteins 05-07-2009
330. 20090117590 Human calcium sensitive potassium channel beta3 subunit proteins, encoding nucleic acid and uses thereof 05-07-2009
331. 20090111997 Method of Generating Amorphous Solid for Water-Insoluble Pharmaceuticals 04-30-2009
332. 20090111832 Imidazolidinone Compounds Useful as Beta-Secretase Inhibitors for the Treatment of Alzheimer's Disease 04-30-2009
333. 20090105479 4-Oxo-1-3-Substituted Phenyl-1,4-Dihydro-1,8-Napthyridene-3-Carboxamide Phosphodiesterase-4 Inhibitor and a Method of Preparing Same 04-23-2009
334. 20090105321 Indole Amide Derivatives as Ep4 Receptot Ligands 04-23-2009
335. 20090105318 Amidoethylthioether Orexin Receptor Antagonists 04-23-2009
336. 20090105310 Glucagon Receptor Antagonist Compounds, Compositions Containing Such Compounds and Methods of Use 04-23-2009
337. 20090105284 Aminocyclohexanes as Dipeptidyl Peptidase-IV for the Treatment or Prevention of Diabetes 04-23-2009
338. 20090105270 Kinase inhibition and anticancer therapy 04-23-2009
339. 20090105265 Pharmaceutical Compositions of Combinations of Dipeptidyl Peptidase-4 Inhibitors With Metformin 04-23-2009
340. 20090105264 Substituted Nicotinamide Compounds - novel class of substituted nicotinamides 04-23-2009
341. 20090105234 EP4 Receptor Agonist, Compositions and Methods Thereof 04-23-2009
342. 20090105228 Heterocyclic benzodiazepine cgrp receptor antagonists 04-23-2009
343. 20090105227 Thienopyrroles As Antiviral Agents - tetracyclic thienopyrrole compounds of formula wherein Ar A 04-23-2009
344. 20090105219 Spirolactam Tricyclic CGRP Receptor Antagonists 04-23-2009
345. 20090105210 Bicyclic Pyrimidines as Dipeptidyl Peptidase-IV Inhibitors for the Treatment or Prevention of Diabetes 04-23-2009
346. 20090105136 NPY Y2 Agonist for Use as Therapeutic Agent for Disease Accompanied by Diarrhea 04-23-2009
347. 20090104220 Method to Make a Peptide-Carrier Conjugate with a High Immunogenicity 04-23-2009
348. 20090104210 Peptide compounds for treating obesity and insulin resistance 04-23-2009
349. 20090099264 Fluoroalkylamine Derivatives as Cathepsin Inhibtors 04-16-2009
350. 20090099226 Quinoline derivatives as ep4 antagonists 04-16-2009
351. 20090099200 Azacyclohexane derivatives as inhibitors of stearoyl-coenzyme a delta-9 desaturase 04-16-2009
352. 20090099168 HIV Integrase inhibitors - Pyridopyrazine- and pyrimidopyrazine-dione compounds are inhibitors of HIV integrase and inhibitors of HIV replication 04-16-2009
353. 20090099126 Ribonucleoside Cyclic Acetal Derivatives for the Treatment of RNA-Dependent RNA Viral Infection 04-16-2009
354. 20090098604 Synthetic gene encoding human epidermal growth factor 2/NEU antigen and uses thereof 04-16-2009
355. 20090098155 Peptide conjugate compositions and methods for the prevention and treatment of alzheimer's disease 04-16-2009
356. 20090093552 Addition of lecithin as an antistatic agent for the crystallization processing of organic molecules 04-09-2009
357. 20090093527 Azacyclopentane Derivatives as Inhibitors of Stearoyl-Coenzyme a Delta-9 Desaturase 04-09-2009
358. 20090093444 Cathepsin Cysteine Protease Inhibitors - This invention relates to a novel class of compounds which are cysteine protease inhibitors including but not 04-09-2009
359. 20090093020 Methods for reducing or eliminating alpha-mannosidase resistant glycans in the production of glycoproteins 04-09-2009
360. 20090092971 Method for Detecting p53 Dysfunction, Method for Molecular Diagnosis of Cancer and Method for Evaluating Compound Effective in Treating Cancer 04-09-2009
361. 20090089889 Neuromedin u receptor subtype 1 deficient transgenic mice and uses thereof 04-02-2009
362. 20090088477 Compounds and methods for leukotriene biosynthesis inhibition 04-02-2009
363. 20090088458 N-(Pyridin-4-Yl)-2-Phenylbutanamides as Androgen Receptor Modulators 04-02-2009
364. 20090088452 Indole Orexin Receptor Antagonists - substituted indole compounds which are antagonists of orexin receptors 04-02-2009
365. 20090088436 P38 Kinase Inhibiting Agents - Compounds described by the chemical formula or pharmaceutically acceptable salts thereof: STR00001 are inhibitors of p38 04-02-2009
366. 20090088431 Heteroaromatic Compounds as Inhibitors of Stearoyl-Coenzyme a Delta-9 Desaturase 04-02-2009
367. 20090082320 Fluorinated 4-azasteroid derivatives as androgen receptor modulators 03-26-2009
368. 20090082308 Benzothiophene derivatives - novel class of benzothiophene amide derivatives 03-26-2009
369. 20090082221 Cross-Species and Multi-Species Display Systems 03-26-2009
370. 20090081681 Method For Genetic Selection Of High-Plasmid Producing E. Coli Clones 03-26-2009
371. 20090081645 METHOD OF ASSUMING DRUG SENSITIVITY TO CDK4 INHIBITOR 03-26-2009
372. 20090076101 Thiophene and Thiazole Substituted Trifluoroethanone Derivatives as Histone Deacetylase (HDAC) Inhibitors 03-19-2009
373. 20090075998 2-(phenyl or heterocyclic)-1H-phenantrho[9,10-d]imidazoles as mPGES-1 inhibitors 03-19-2009
374. 20090075979 CETP Inhibitors - Compounds having the structure of Formula including pharmaceutically acceptable salts of the compounds 03-19-2009
375. 20090075869 HCV NS3 protease inhibitors - macrocyclic compounds of formula that are useful as inhibitors of the hepatitis C virus NS3 protease 03-19-2009
376. 20090075319 Method of Detecting Reactive Metabolite - method of detecting a reactive metabolite which comprises steps of conducting a metabolic reaction of a test 03-19-2009
377. 20090074890 Substituted Triazoles as Sodium Channel Blockers 03-19-2009
378. 20090069391 Benzothiophene hydroxamic acid derivatives 03-12-2009
379. 20090069385 Antidiabetic Oxazolidinediones and Thiazolidinediones 03-12-2009
380. 20090069376 VLA-4 Antagonists - Substituted N--[N-sulfonyl-prolyl]-phenylalanine derivatives of the present invention are antagonists of the VLA-4 integrin and are 03-12-2009
381. 20090069344 Modulators of hcv replication - compounds of formula : STR00001 where X, Y, R 03-12-2009
382. 20090069312 Potassium Channel Inhibitors - dipyridin-3-ylmethoxy compounds and derivatives thereof having the structure I useful as potassium channel inhibitors to 03-12-2009
383. 20090069284 Substituted 3-alkyl and 3-alkenyl azetidine derivatives 03-12-2009
384. 20090069283 Potassium Channel Inhibitors - pyridine substituted ethanol compounds and derivatives thereof having the structure useful as potassium channel 03-12-2009
385. 20090069250 Inhibitors of Histone Deacetylase - novel class of compounds 03-12-2009
386. 20090068678 Method for identifying modulators of NOAH10 useful for treating Alzheimer's disease 03-12-2009
387. 20090062349 1-Hydroxycycloalkanecarboxamide derivatives 03-05-2009
388. 20090062327 Inhibitors of AKT Activity - The instant invention provides for compounds that inhibit Akt activity 03-05-2009
389. 20090062302 Jak2 Tyrosine Kinase Inhibition - methods for inhibiting JAK2 tyrosine kinase 03-05-2009
390. 20090062297 Hydroxyalkylarylamide Derivatives - novel class of hydroxyalkylarylamide derivatives 03-05-2009
391. 20090062293 1,4-Substituted Piperazine Derivatives - compound represented by the formula : STR00001 or a pharmaceutically acceptable salt thereof, wherein: R 03-05-2009
392. 20090062280 Ophthalmic Compositions for Treating Ocular Hypertension 03-05-2009
393. 20090062269 Niacin Receptor Agonists, Compositions Containing Such Compounds and Methods of Treatment 03-05-2009
394. 20090054662 Process for synthesizing a substituted pyrazole 02-26-2009
395. 20090054506 Glucagon receptor antagonist compounds, compositions containing such compounds and methods of use 02-26-2009
396. 20090054483 Substituted Quinolines as Inhibitors of Leukotriene Biosynthesis 02-26-2009
397. 20090054462 Hydroisoindoline tachykinin receptor antagonists 02-26-2009
398. 20090054448 Amino Acid Derivatives as Histone Deacetylase (HDAC) Inhibitors 02-26-2009
399. 20090054440 Quinoline derivatives as neurokinin receptor antagonists 02-26-2009
400. 20090054423 Niacin receptor agonists, compositions containing such compounds and methods of treatment 02-26-2009
401. 20090054408 Monocyclic anilide spirolactam cgrp receptor antagonists 02-26-2009
402. 20090054399 HIV INTEGRASE INHIBITORS - Tricyclic compounds of Formula are inhibitors of HIV integrase and inhibitors of HIV replication: wherein bond a, ring A, R 02-26-2009
403. 20090048308 VLA-4 Antagonists - 4-Thio 4-sulfinyl and 4-sulfonyl proline derivatives of the present invention are antagonists of the VLA-4 integrin and are useful 02-19-2009
404. 20090048283 Salt of an androgen receptor modulator - The biphthalate salts of compound I are modulators of the androgen receptor in a tissue selective manner 02-19-2009
405. 20090048276 Inhibitors of Fatty Acid Synthase (Fas) - The instant invention provides for compounds which comprise substituted 3-aryl-4-hydroxyquinolin-2-ones that 02-19-2009
406. 20090048248 Octahydropyrano[3,4-C]Pyrrole Tachykinin Receptor Antagonists 02-19-2009
407. 20090048239 Therapeutic compounds - class of macrocyclic compounds of formula , wherein R 02-19-2009
408. 20090048228 Heterocycle Derivatives As Histone Deacetylase (Hdac) Inhibitors 02-19-2009
409. 20090048227 Substituted-1-Phthalazinamines As Vr- 1 Antagonists 02-19-2009
410. 20090047702 Method for Identifying Modulators of Keah6 Useful for Treating Alzheimer's Disease 02-19-2009
411. 20090047303 Method for improving the immunogenicity of plasmodium antigens 02-19-2009
412. 20090042966 Mitotic Kinesin Inhibitors - fluorinated dihydropyrazole compounds that are useful for treating cellular proliferative diseases 02-12-2009
413. 20090042954 2-(Aryl)Azacyclylmethyl Carboxylates, Sulfonates, Phosphonates, Phosphinates and Heterocycles as S1p Receptor Antagonists 02-12-2009
414. 20090042944 Potassium Channel Inhibitors - compounds having the structure useful as potassium channel inhibitors to treat cardiac arrhythmias, and the like 02-12-2009
415. 20090042926 Niacin Receptor Agonists, Compositions Containing Such Compounds and Methods of Treatment 02-12-2009
416. 20090042892 Cetp Inhibitors - Compounds having the structure of Formula including pharmaceutically acceptable salts of the compounds 02-12-2009
417. 20090042854 Hexahydro-3H-Pyrrolizin-3-Ones Useful as Tachykinin Receptor Antagonists 02-12-2009
418. 20090036503 Triazole Derivatives as Inhibitors of 11-Beta-Hydroxysteroid Dehydrogenase-1 02-05-2009
419. 20090036443 Thienopyrroles as antiviral agents - thienopyrrole compounds of formula 02-05-2009
420. 20090035277 Hepatitis C Virus Nucleic Acid Vaccine - The present invention features nucleic acid constructs that can be used as a HCV nucleic acid vaccine 02-05-2009
421. 20090030048 Novel pharmaceutical compounds - The instant invention provides compounds of Formula Ia which are leukotriene biosynthesis inhibitors 01-29-2009
422. 20090030043 Potassium Channel Inhibitors - tetraaryl methyl amine compounds and derivatives thereof having the structure useful as potassium channel inhibitors to 01-29-2009
423. 20090030012 Pyridine, Pyrimidine and Pyrazine Derivatives as Cxcr3 Receptor Modulators 01-29-2009
424. 20090029406 Npy Y4 Agonist as Therapeutic Agent for Disease Accompanied by Intestinal Tract Dysfunction 01-29-2009
425. 20090025095 Method for Evaluating Compound Using Barlp and Substance for Regulating Eating and Body Weight 01-22-2009
426. 20090023774 Pyridine analogs as C5A antagonists - novel compounds of Formula I which are antagonists of the C5a receptor 01-22-2009
427. 20090023767 Inhibitors of Checkpoint Kinases - The instant invention provides for compounds which comprise fused pyrazoles that inhibit CHK1 activity 01-22-2009
428. 20090023163 Method of Measuring Enzyme Activity and Method of Evaluating Compound 01-22-2009
429. 20090018340 Formation of Tetra-Substituted Enamides and Stereoselective Reduction Thereof 01-15-2009
430. 20090018056 Heteroarylcarbamoylbenzene derivatives 01-15-2009
431. 20090018054 Cholesteryl Ester Transfer Protein Inhibitors 01-15-2009
432. 20090017468 METHOD OF SCREENING COMPOUND DIRECTLY ACTIVATING GLYCOGEN SYNTHASE 01-15-2009
433. 20090012134 Arylsulfonyl Benzofused Heterocycles as 5-Ht2a Antagonists 01-08-2009
434. 20090012076 Tyrosine kinase inhibitors - 5H-benzo[4 5]cyclohepta[1 2-b]pyridine derivatives 01-08-2009
435. 20090012075 Fluorinated Arylamide Derivatives - novel class of fluorinated arylamide derivatives 01-08-2009
436. 20090012061 A Method of Treating Cancer - method of treating cellular proliferative diseases in particular cancer 01-08-2009
437. 20090007283 Transgenic Rodents Selectively Expressing Human B1 Bradykinin Receptor Protein 01-01-2009
438. 20090005418 Mitotic Kinesin Inhibitors - dihydroisoxazoles that are useful for treating cellular proliferative diseases 01-01-2009
439. 20090005389 2,5 Diaza-Bicyclo [2.2.1] Heptane Derivatives as Calcium Channel Blockers 01-01-2009
440. 20090005323 Cathepsin K Inhibitors and Obesity - This invention relates to the treatment of obesity the treatment of obesity related disorders prevention of weight 01-01-2009
441. 20080318976 Alpha-Hydroxy Amides as Bradykinin Antagonists or Inverse Agonists 12-25-2008
442. 20080318930 Sulfonyl Compound as Inhibitors of 11-Beta-Hydroxysteroid Dehydrogenase-1 12-25-2008
443. 20080318927 Substituted monocyclic CGRP receptor antagonists 12-25-2008
444. 20080318310 Method and Apparatus for Automatically Isolating Microbial Species 12-25-2008
445. 20080312286 Indanone Potentiators of Metabotropic Glutamate Receptors 12-18-2008
446. 20080312274 Quinoline Derivatives as Neurokinin Receptor Antagonists 12-18-2008
447. 20080311137 Carcinoembryonic Antigen Fusions and Uses Thereof 12-18-2008
448. 20080306139 Antibiotic Compounds - Fermentation of a nutrient medium with a eubacterium Streptomyces sp 12-11-2008
449. 20080305081 Novel aminopyrimidine derivatives as PLK1 inhibitors 12-11-2008
450. 20080300261 Arylacetic Acids and Related Compounds for Treatment of Alzheimer's Disease 12-04-2008
451. 20080299616 Malate Synthase Regulatory Sequences for Heterologous Gene Expression in Pichia 12-04-2008
452. 20080293684 Heterocyclic Acetophenone Potentiators of Metabotropic Glutamate Receptors 11-27-2008
453. 20080287523 Pyrrolidin-3-Yl Compounds Useful as Beta-Secretase Inhibitors for the Treatment of Alzheimer's Disease 11-20-2008
454. 20080287489 Ophthalmic compositions for treating ocular hypertension 11-20-2008
455. 20080287457 Inhibitors of Akt Activity - compounds which contain substituted naphthyridines which inhibit the activity of Akt 11-20-2008
456. 20080287414 Mitotic Kinesin Inhibitors - tricyclic pyrazoles according to Formula that are useful for treating cellular proliferative diseases 11-20-2008
457. 20080287394 Hiv Integrase Inhibitors - Hydroxy-substituted pyrazinopyrrolopyridazine dione compounds are inhibitors of HIV integrase and inhibitors of HIV 11-20-2008
458. 20080286275 Antigen Binding Proteins Directed Against Scavenger Receptor B1 that Inhibit Hcv Replication 11-20-2008
459. 20080280966 Hydroisoindoline Tachykinin Receptor Antagonists 11-13-2008
460. 20080280956 Heteroarylsulfonyl Stilbenes as 5-Ht2a Antagonists 11-13-2008
461. 20080280945 Crystalline forms of an HIV integrase inhibitor 11-13-2008
462. 20080280902 Inhibitors of Checkpoint Kinases - The instant invention provides for compounds which comprise substituted quinolinones that inhibit CHK1 activity 11-13-2008
463. 20080280899 Inhibitors of Akt Activity - compounds which contain substituted napthyridines which inhibit the activity of Akt 11-13-2008
464. 20080280889 Inhibitors of Akt Activity - compounds which contain substituted pyridazines and pyrimidines moieties which inhibit the activity of Akt 11-13-2008
465. 20080280873 Biaryl Substituted Pyrazinones as Sodium Channel Blockers 11-13-2008
466. 20080280857 CGRP receptor antagonists - compounds of Formula I: and Formula II: useful as antagonists of CGRP receptors and useful in the treatment or prevention of 11-13-2008
467. 20080280842 Fluorinated Pyrrolo[2,3-D]Pyrimidine Nucleosides for the Treatment of Rna-Dependent Rna Viral Infection 11-13-2008
468. 20080280836 Anti-hypercholesterolemic biaryl azetidinone compounds 11-13-2008
469. 20080280313 Coccidian Parasite Casein Kinase I as a Chemotherapeutic Target for Antiprotozoal Agents 11-13-2008
470. 20080275097 Non-nucleoside reverse transcriptase inhibitors 11-06-2008
471. 20080275069 Quinazoline Derivative - compound or its pharmaceutically-acceptable salt of formula wherein R 11-06-2008
472. 20080275004 N-Substituted hydroxypyrimidinone carboxamide inhibitors of HIV integrase 11-06-2008
473. 20080274498 Methods for producing modified glycoproteins 11-06-2008
474. 20080274476 Assay Method - There is disclosed a method for determining the activity of gamma-secretase in a text subject, using a biological sample from the subject 11-06-2008
475. 20080274452 Process For Large Scale Production Of Plasmid Dna By E.Coli Fermentation 11-06-2008
476. 20080274107 Tyrosine kinase inhibitors - compounds which inhibit regulate and/or modulate tyrosine kinase signal transduction 11-06-2008
477. 20080269302 Macrocyclic Tertiary Amine Beta-Secretase Inhibitors for the Treatment of Alzheimer's Disease 10-30-2008
478. 20080269287 Substituted Pyridone Derivative - Compounds of a formula [wherein A represents formula R3 is a hydrogen lower alkyl et al 10-30-2008
479. 20080269279 Substituted furo[2,3-B] pyridine derivatives as cannabinoid-1 receptor modulators 10-30-2008
480. 20080269182 Method of treating cancers with SAHA and Pemetrexed 10-30-2008
481. 20080262051 Triazole derivatives which are SMO antagonists 10-23-2008
482. 20080262046 Amidopropoxyphenyl Orexin Receptor Antagonists 10-23-2008
483. 20080262035 Amide Derivatives as Inhibitors of Histone Deacetylase 10-23-2008
484. 20080261972 Cgrp Receptor Antagonists - Compounds of Formula 10-23-2008
485. 20080261944 Indole Derivatives as Antiviral Agents - indole compounds of the formula : wherein R 10-23-2008
486. 20080261938 Tetracyclic Indole Derivatives as Antiviral Agents 10-23-2008
487. 20080255216 Diaryltriazoles as Inhibitors of 11-Beta-Hydroxysteroid Dehydrogenase-1 10-16-2008
488. 20080255072 Composition for Inhibition of Cathepsin K 10-16-2008
489. 20080254059 Adenovirus Serotype 26 Vectors, Nucleic Acid and Viruses Produced Thereby 10-16-2008
490. 20080249146 Imidazole and Thioazole Derivatives as Antiviral Agents 10-09-2008
491. 20080249093 (3,4-Disubstituted)Propanoic Carboxylates as Sip (Edg) Receptor Agonists 10-09-2008
492. 20080248062 Papillomavirus vaccine compositions - pharmaceutical compositions comprising virus-like particles of HPV 10-09-2008
493. 20080248040 Nucleic Acid Molecules Encoding Novel Human Low-Voltage Activated Calcium Channel Proteins, Designed-Alpha 1I-1 and Alpha 1I-2, Encoded Proteins and Methods of Use Thereof 10-09-2008
494. 20080242722 Combination Therapy for Treating Cyclooxygenase-2 Mediated Diseases or Conditions in Patients at Risk of Thrombotic Cardiovascular Events 10-02-2008
495. 20080242657 Treatment of Tremor with Histamine H3 Inverse Agonists or Hist Amine H3 Antagonists 10-02-2008
496. 20080242643 Nitric Oxide Releasing Prodrugs of Diaryl-2-(5H)-Furanones as Cyclooxygenase-2 Inhibitors 10-02-2008
497. 20080242597 Antibiotic compounds - novel thiazolyl peptide antibiotics capable of treating serious bacterial infections in mammals 10-02-2008
498. 20080234281 Mitotic Kinesin Inhibitors - N-substituted benzylic aniline derivatives that are useful for treating cellular proliferative diseases 09-25-2008
499. 20080227786 Novel Crystalline Salts of a Dipeptidyl Peptidase-IV Inhibitor 09-18-2008
500. 20080227778 Isoquinolinone Potassium Channel Inhibitors 09-18-2008
501. 20080227758 Nitric Oxide Releasing Prodrugs of Diaryl-2-(5h)-Furanones as Cyclooxygenase-2 Inhibitors 09-18-2008
502. 20080226660 Optimized Expression of Hpv 58 L1 in Yeast 09-18-2008
503. 20080221198 Novel Crystalline Forms of Antidiabetic Compounds 09-11-2008
504. 20080221157 Amide Derivatives as Inhibitors of Histone Deacetylase 09-11-2008
505. 20080214594 Inhibitors Of Checkpoint Kinases - The instant invention provides for compounds which comprise fused pyrazoles that inhibit CHK1 activity 09-04-2008
506. 20080214522 Antiviral indoles - Compounds of the formula : wherein A, B, D, M, Ar, W, X, Y, Z and R 09-04-2008
507. 20080214511 Tricyclic Anilide Spirolactam Cgrp Receptor Antagonists 09-04-2008
508. 20080207693 Mitotic Kinesin Inhibitors - dihydropyrazole compounds that are useful for treating cellular proliferative diseases 08-28-2008
509. 20080207666 Substituted pyrano[2,3-B]pyridine derivatives as cannabinoid-1 receptor modulators 08-28-2008
510. 20080206786 Trace amine receptor 1 of the african green monkey 08-28-2008
511. 20080200513 Pyridine N-Oxides As Antiviral Agents - pyridinone derivatives of formula : wherein Z represents C 08-21-2008
512. 20080200494 Imidazopyridine Derivatives - The invention provides imidazopyridine derivatives represented by the general formula [I] [in which R 08-21-2008
513. 20080200376 Compositions and Methods For the Treatment Of Obesity and Sexual Dysfunction 08-21-2008
514. 20080199942 Method of engineering a cytidine monophosphate-sialic acid synthetic pathway in fungi and yeast 08-21-2008
515. 20080199459 Mitotic Kinesin Inhibitors - dihydropyrrole compounds that are useful for treating cellular proliferative diseases 08-21-2008