Tumor removal

Tumor removal is a surgical procedure to remove an abnormal growth.

A tumor can be either benign, like a wart, or malignant, in which case it isa cancer. Benign tumors are well circumscribed and are generally easy to remove completely. In contrast, cancers pose some of the most difficult problemsin all of surgery.

Currently 40% of all cancers are treated with surgery alone. In 55%, surgeryis combined with other treatments--usually radiation therapy or chemotherapy.

The doctor needs to decide if surgery should be done at all. Because cancersspread (metastasize) to normal tissues, sometimes at the other end of the body, the ability of surgery to cure must be addressed at the outset. As long asthe cancer is localized, the initial presumption is that cure should be attempted by removing it as soon as possible.

Non-curative surgery may make other treatments more effective. "Debulking" acancer--making it smaller--is thought to assist radiation and chemotherapy toget to the remaining pieces of the cancer and be more effective.

Another important function surgery performs in cancer treatment is accuratelyassessing the nature and extent of the cancer. Most cancers cannot be adequately identified without a piece being placed under a microscope. This piece is obtained by surgery. Surgery is also the only way to determine exactly howfar the tumor has spread. There are a few standard methods of comparing one cancer to another for the purposes of comparing treatments and estimating outcomes. These methods are called "staging." The most universal method is the TNM system.

  • "T" stands for "tumor" and reflects the size of the tumor.
  • "N" represents the spread of the cancer to lymph nodes, largely determined by those nodes removed at surgery that contain cancer cells. Since cancers spread mostly through the lymph system, this is a useful measure of theirability to disperse.
  • "M" refers to the metastases, how far they arefrom the original cancer and how often they have multiplied.

Other methods of staging include Duke's method and similar systems, which addto the above criteria the degree of invasion of the cancer into the surrounding tissues.

Staging is particularly important with lymphomas such as Hodgkin's disease. These cancers may appear in many places in the lymphatic system. Because theyare very radiosensitive, radiation treatment is often curative if all the cancer is irradiated. Therefore, it must all be located. Surgery is a common, usually essential, method of performing this staging. If the disease is too widespread, the staging procedure will dictate chemotherapy instead of radiation.

Curative cancer surgery demands special considerations. There is a danger ofspreading or seeding the cancer during the process of removing it. Presumingthe cancer cells can grow almost anywhere in the body they end up, the surgeon must not "spill" cells into the operating field or "knock them loose" intothe blood stream. Special techniques called "block resection" and "no touch"are used. Block resection means taking the entire specimen out as a single piece. "No touch" means that only the normal tissue removed with specimen is handled; the cancer itself is never touched. This prevents "squeezing" cancer cells out into the circulation. Further, in this technique pains are taken toclamp off the blood supply first, preventing cells from leaving by that routelater in the surgery.

To diagnose cancer, four types of biopsy techniques are used:

  • Aspiration biopsy. A needle is inserted into the tumor and a sample is withdrawn.
  • Needle biopsy. A special cutting needle is inserted into the core of the tumor and a core sample is cut out.
  • Incisional biopsy. A portion of a large tumor is removed, usually before complete tumor removal.
  • Excisional biopsy. A whole lesion is removed along with surrounding normal tissue.

Once surgical removal has been decided, an oncologic surgeon will remove thetumor whole, taking with it a large section of the surrounding normal tissue.The healthy tissue is removed to minimize the risk of possible seeding.

When surgical removal of a tumor is unacceptable as a sole treatment, a portion of the tumor is removed to "debulk" the mass. Debulking aids radiation andchemotherapy treatments.

Retesting and periodical examinations are necessary to ensure that a tumor has not reformed after total removal.

The possibility of mestastasis and seeding are risks that have to be considered in consultation with an oncologist.

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