Infectious Mononucleosis - Treatment

The most effective treatment for mononucleosis is rest because a person's body needs time to fight off the infection. Individuals with mild cases may not require bed rest, but they should restrict their physical activity. In any case, vigorous physical activity, such as athletics or heavy lifting, should be avoided. Such activities can cause the spleen to rupture, making the condition much more serious.

Treatments are available for the symptoms of mononucleosis. For example, drinking water and fruit juices can help relieve the sore throat and dehydration that often accompany mononucleosis. Gargling with salt water or taking throat lozenges may also relieve discomfort. Over-the-counter medications, such as acetaminophen (pronounced uh-see-tuh-MIN-uh-fuhn, trade name Tylenol) or ibuprofen (pronounced i-byoo-PRO-fuhn, trade name Advil), may relieve symptoms such as fever and headache. Aspirin should not be given to children because it may cause Reye's syndrome (see Reye's syndrome entry), a serious illness.

Antibiotics are not effective in curing mononucleosis. However, they may be helpful in treating some symptoms of the disease. For example, they may help relieve the discomfort of the sore throat that often occurs with mononucleosis. Cortisone can also be used to reduce swelling and inflammation in the throat and tonsils.