Infectious Mononucleosis - Prognosis
Most people recover from mononucleosis in about two to three weeks. They are then able to resume their normal activities, especially if they rested during their illness. A patient may not feel completely recovered, however, for a period of up to three months after being cured.
One of the most common problems in treating mononucleosis is that people are eager to return to their usual activities too quickly. When that happens, the disease may return. Once the disease has completely run its course, a person cannot be reinfected.

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