Resistance to herpes stromal keratitis conferred by an IgG2a-derived peptide

Article Abstract:

Research on mice demonstrates that exposure to an IgG2a-derived, allotype-bearing peptide can confer a resistance to herpes stromal keratitis (HSK), a virally induced autoimmune reaction. The peptide is recognized by T-cell clones specific for corneal self antigens which also mediate HSK. Therefore, self-tolerance and autoimmunity prevention may be maintained due to sequestered tissue proteins and circulating proteins sharing peptide subsequence expressions.

author: Rodriguez, Alejandro, Foster, C. Stephen, Bikoff, Elizabeth K., Avery, Anne C., Zhao, Zi-Shan, Soheilian, Masoud, Cantor, Harvey
Physiological aspects, Immunological tolerance, Immunologic tolerance, Herpes, Keratitis

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An unusual social display by gorillas

Article Abstract:

Issues are presented concerning the generation of large splash displays by wild silverback western lowland gorillas. The antagonistic nature of the displays and the social interaction of the gorillas are discussed.

author: Buchanan-Smith, Hannah M., Parnell, Richard J.
Behavior, Observations, Social behavior in animals, Animal social behavior

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KSHV-like herpesviruses in chimps and gorillas

Article Abstract:

Issues are presented concerning the discovery of a virus similar to the Kaposi's-sarcoma-associated herpes-virus in 5 gorillas and 25 chimpanzees whose blood was sampled in wild populations in West Africa.

author: Lewis, John, Georges-Courbot, Marie-Claude, Lacoste, Vincent, Mauclere, Philippe, Dubreuil, Guy, Gessain, Antoine
Diseases, Chimpanzees, Kaposi's sarcoma

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subjects list: Research, Herpesvirus diseases, Herpesvirus infections, Gorillas
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