Interaction of the erythropoietin and stem-cell-factor receptors

Article Abstract:

Erythropoietin (EPO) is essential for the growth and survival of HCD57 cells, an EPO-dependent erythroid-progenitor cell line expressing high levels of KIT, but the KIT ligand stem-cell factor (SCF) receptor can substitute for EPO as long as both KIT and EPO receptors are expressed. KIT can be activated by EPO receptor tyrosine phosphorylation that is induced by SCF. Therefore, both KIT and SCF are essential for non-haematopoietic survival, migration and proliferation as well as the further proliferation and maturation of colony-forming unit erythriod.

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The meaning of life

Article Abstract:

Issues are presented concerning the disagreements which have occurred between scientists working on embryonic stem cell research and 'pro-life' groups over the point at which an embryo becomes a human being.

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IVF and the history of stem cells

Article Abstract:

The importance of research on stem cells is examined in detail, with a history of that research, and legal and ethical issues explained.

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