Developmental and activity-dependent regulation of kainate receptors at thalamocortical synapses

Article Abstract:

Fast excitatory synaptic transmission in the mammalian brain is mostly mediated by ionotrophic glutamate receptors. The three subtypes of these receptors are AMPA, NMDA and kainate. Kainate-receptor subunits are expressed widely in the mammalian central nervous system. The developing thalamocortical synapses are shown to express postsynaptic kainate receptors along with AMPA receptors, although the two subtypes do not co-localize. The kainate receptor contribution to transmission falls during the period for experience-dependent plasticity.

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Identification of genes that modify ataxin-1-induced neurodegeneration

Article Abstract:

Research on genetic aspects of neurodegeneration liked to ataxin-1, is examined in detail.

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Transformation from temporal to rate coding in a somatosensory thalamocortical pathway

Article Abstract:

The somatosensory thalamocortical pathway is discussed.

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