Aberrant CFTR-dependent HCO(sub 3)(super -) transport in mutations associated with cystic fibrosis

Article Abstract:

Research is presented concerning the influence and importance of HCO(sub 3)(super -) transport in cystic fibrosis and in the function of secretory epithelia. Wild type cystic fibrosis transmembrane conductance regulator was compared with 17 mutants.

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Bilingual bacteria

Article Abstract:

The cholera causing bilingual bacterium, Vibrio cholerae, uses two distinct signaling molecules to inhibit its virulence. The functions and identity of the two signals are reported.

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Quorum-sensing signals indicate that cystic fibrosis lungs are infected with bacterial biofilms

Article Abstract:

Cystic fibrosis sputum was found to produce P-aeruginosa quorum-sensing signals.

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