A freely diffusible form of Sonic hedgehog mediates long-range signalling

Article Abstract:

Evidence is presented for a freely diffusible form of Sonic hedgehog that is multimeric, cholesterol modified and biologically potent. It is shown that the native form's availability is regulated by two functional antagonists of the Sonic hedgehog pathway.

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Gene expression in Pseudomonas aeruginosa biofilms

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Research is presented describing the study of opportunitistic pathogenic bacteria and the role of biofilm lifestyles in preventing persistent infections.

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Networks of nanotubes and containers

Article Abstract:

Research is presented describing the study of complex fluid membrane networks for the benefit of microfluidics and microelectronics.

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