A conditioned dendritic cell can be a temporal bridge between a CD4 plus T-helper and a T-killer cell

Article Abstract:

Antigenspecific T-killer and T-helper cells have to locate each other if they are to generate immune responses. They are unable to detect each other, but they can use a dendritic cell displaying antigens to both of them. The three cell types are migratory and uncommon, so it seems unlikely that they will interact together. They need not meet simultaneously, however. The helper cell may initially condition dendritic cells which are then able to stimulate killer cells.

author: Matzinger, Polly, Ridge, John Paul, Rosa, Francesca Di
T cell antigen receptors, T cells, Dendrites

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End game for B cells

Article Abstract:

Issues are presented concerning the important role played by plasma cells in the immune system. Their ability to secrete antibodies to dispatch invading cells and the discovery of the protein required for plasma cell production are discussed.

author: Calame, Kathryn
Evaluation, Cover Story, Plasma cells

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Antibody alterations

Article Abstract:

Issues are presented concerning the change which occurs in antibody molecules as part of the response of the immune system. The ability of the altered antibody molecules to bind with intruding molecules is discussed.

author: Martin, Alberto, Scharff, Matthew D.

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subjects list: Research, Analysis, Immunological research, Immunologic research, Physiological aspects, Antibodies
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