A blueprint of 'bad air'

Article Abstract:

Bowman and colleagues have revealed the entire sequence of the Plasmodium falciparum chromosome 3, giving 7% of the total P. falciparum genome. The genome is complex but there is a certain organization where clusters of genes encoding proteins produced at similar stages in the life cycle appear to be grouped in certain chromosomes. The genome sequence should be used to identify new drug targets, to help in developing vaccines and to understand the pathogenesis of malaria.

User Contributions:

Comment about this article or add new information about this topic:

Comment:  (50-4000 characters)

Name:

E-mail:

Security Code:

The worm revealed

Article Abstract:

The Caenorhabditis elegans Genome Project started in 1983, and the project later sought to obtain the complete genome sequence of the worm. This sequencing has been described as essentially complete, and has yielded the largest genome sequenced to date, and the first genome sequence for a multicellular organism. This project shows that complex genomes can be sequenced, and provides a model for genome efforts.

User Contributions:

Comment about this article or add new information about this topic:

Comment:  (50-4000 characters)

Name:

E-mail:

Security Code:

Functional links between proteins

Article Abstract:

Marcotte and colleagues and Enright and colleagues have developed computational methods associating proteins through properties other than their similar amino-acid sequences. They have compared phylogenetic profiles and expression patterns and as there is no reliance on direct sequence similarity, the method will find many applications in genomics.

User Contributions:

Comment about this article or add new information about this topic:

Comment:  (50-4000 characters)

Name:

E-mail:

Security Code: