Evaluation of the anti-inflammatory activity of zhankuic acids isolated from the fruiting bodies of Antrodia camphorata

Article Abstract:

The fruiting body of Antrodia camphorata (Polyporaceae) was traditionally used for the treatment of diarrhea, abdominal pain, hypertension, cancer, and so on. A study established an acute cellular model in isolated peripheral human neutrophils is presented to examine the anti-inflammatory effects of zhankuic acids identified from A. camphorata.

author: Yuh-Chiang Shen, Yea-Hwey Wang, Yueh-Ching Chou, Chieh-Fu Chen, Cheng-Jen Chou, Lie-Chwen Lin, Jung-Hsiung Tien, Tun-Tschu Chang

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Intestinal anti-inflammatory activity of paepalantine, an isocoumarin isolated from the capitula of paepalanthus bromelioides, in the trinitrobenzenesulphonic acid model of rat colitis

Article Abstract:

Paepalantine, an isocoumarin isolated from the capitula of Paepalanthus bromelioides, was tested for its anti-inflammatory properties in the trinitrobenzenesulphonic acid (TNBS) model of rat colitis. This was done under two experimental conditions, when the colonic mucosa is intact or when the mucosa is recovering from previous damage.

author: Di Stasi, Luiz C., Camuesco, Desireem, Vilegas, Wagner, Nieto, Ana, Zarzuelo, Antonio, Galvez, Julio
Antioxidants, Antioxidants (Nutrients)

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In vitro anti-inflammatory activity of panduratin A isolated from Kaempferia pandurata in RAW 264.7 cells

Article Abstract:

An active compound, panduratin A, was isolated from a methanol extract of Kaempferia pandurata (Zingiberaceae). An examination suggests that panduratin A could exert its inhibitory effects on the production of NO and PGE2 through the suppression of NF-kB activation, thus showing its potential for use as an anti-inflammatory agent.

author: Jung-Mi Yun, Hoonjeong Kwon, Jae-Kwan Hwang
COX-2 inhibitors, Zingiberaceae

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subjects list: Research, United States, Medicinal plants, Anti-inflammatory drugs, Anti-inflammatory agents
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