Advances in vascular neuroeffector mechanisms

Article Abstract:

A symposium was held during the 1998 International Congress of Pharmacology in Porto, Portugal, emphasizing on developments in the field of vascular function. Composed of five sessions, the meeting specifically focused on vascular neuroeffector mechanisms. The subjects discussed included mechanisms involved in neurotransmission at the vascular level, intrinsic pathways leading to vascular smooth muscle contraction and relaxation, and pre- and post-junctional adrenoreceptors.

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Peripheral versus central mechanisms in the behavioral effects of cytokines

Article Abstract:

Researchers continue to study the action of cytokines on the peripheral and central regions of the brain. Cytokines such as IL-1 and other pyrogens are pro-inflammatroy agents which are often causes of inflammation and pain at the sites of injection. Its effect is greatest at the brain, where it affects gut function and at the liver, where it induces the release of acute-phase proteins.

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Chromaffin cell mechanisms: understanding catecholamine storage and release

Article Abstract:

Researchers at a conference discussed the synthesis and release of catecholamines by chromaffin cells. Topics included the biosynthesis of transmitters, packaging of the granule core, the triggering of exocytosis, and the actions of the contents on target cells.

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