The effect of specific hormones on fibrinolysis in pregnancy

Article Abstract:

Hydrocortisone appears to play a role in the increased tendency to form blood clots that is characteristic of late pregnancy. Researchers cultured blood vessel lining cells from umbilical cord veins and measured the production of clotting promoters and inhibitors in the presence of the hormones hydrocortisone, estrogen, progesterone, and prolactin. Hormones were added in concentrations duplicating those found in the blood of pregnant women. Only hydrocortisone significantly increased the production of factors facilitating clot formation.

Author: Vintzileos, Anthony M., Knuppel, Robert A., Houlihan, Christopher M., Guo, Jian-Zhong, Hahn, Do Won
Physiological aspects, Hydrocortisone, Fibrinolysis

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Analysis of repeat cesarean delivery indications: implications of heterogeneity

Article Abstract:

Modifying practice patterns could increase the vaginal birth after cesarean rate. Of 376 women who had at least one prior cesarean section, 45% had an elective cesarean delivery and 31% labored, but the labor ended in another cesarean. Women with insurance were seven times more likely to have an elective cesarean compared with Medicaid or self-pay patients. Women who labored but had a repeat cesarean were more likely to have labor induced, not to have the amniotic sac artificially broken, and to have early placement of an epidural.

Author: Vintzileos, Anthony M., Smulian, John C., Lake, Marian F., Hanley, Maryellen L., McLean, David A.
Analysis, Planning, Cesarean section, Vaginal birth after cesarean

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