The association of estrogen replacement therapy and the Raynaud phenomenon in postmenopausal women

Article Abstract:

Estrogen replacement therapy with estrogen alone may increase a woman's risk of Raynaud syndrome. Raynaud syndrome causes blood vessels to contract, which increases cold sensitivity, and there is evidence that hormones are involved. In 497 postmenopausal women participating in the Framingham Offspring Study, those who used estrogen alone were 2.5 times more likely to experience symptoms of Raynaud syndrome compared to women who were not using hormone therapy. Women who took estrogen and progesterone had the same risk as non-users.

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In some women, postmenopausal hormone use increases short-term risk for heart disease, but decreases risk in the long term

Article Abstract:

Women with a history of coronary artery disease or heart attack who take hormone replacement therapy have an increased risk of another heart attack in the short term but a lower risk in the long term. This was true regardless of whether the treatment was estrogen only or estrogen combined with progestin.

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Hormone replacement therapy in postmenopausal women with heart disease and risk for gallstones that require surgery

Article Abstract:

Hormone replacement therapy may increase a woman's risk of gallstones, particularly large gallstones that would require surgery. This was the conclusion of researchers who studied 2,253 postmenopausal women.

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