Recent advances in the development of HIV-1 vaccines using replication-incompetent adenovirus vectors

Article Abstract:

The difficulties in developing an effective AIDS vaccine have served to highlight the deficiencies in the overall understanding of the underlying virologic and immunologic processes. The salient features of these difficulties include the virus's high degree of genetic diversity, resistance to neutralization by antibodies, and relentless destruction of the host's immune system.

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Mechanisms of pulmonary fibrosis

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The concept of pulmonary fibrosis as a dysregulated repair process in the variation of classical inflammatory is presented. The environmental factors and host response factors that may influence these varied manifestations are discussed.

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Lead poisoning

Article Abstract:

The surveys on lead research, and evolving knowledge of the distribution, toxicology, and remediation of lead toxicity are presented. The most important organic network affected by lead is the toxicology central nervous system (CNS).

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