Do Statins Prevent Both Cardiovascular Disease and Fracture?

Article Abstract:

Controlled clinical trials will be necessary to determine whether drugs called statins can lower the risk of bone fractures. Statins are used to reduce blood cholesterol levels and lower the risk of cardiovascular disease. Two studies published in 2000 found that statins may lower the risk of bone fractures. Animal studies have shown that statins can increase bone mass, so this may explain these results. However, the studies were both observational studies, not controlled clinical trials. Until such clinical trials are done, people with osteoporosis should not be treated with statins unless they also have high cholesterol levels.

author: Cummings, Steven R., Bauer, Douglas C.
Editorial, Bones, Anticholesteremic agents

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Relationship of changes in physical activity and mortality among older women

Article Abstract:

Regular physical exercise can lower an elderly woman's risk of death by 50%, according to a study of 7,553 women 65 years old or older. Women 75 years old and older and those with poor health may not benefit as much from exercise as younger, healthier women. Most research on the health benefits of exercise have focused on middle-aged people.

author: Cummings, Steven R., Ensrud, Kristine E., Cauley, Jane A., Bauer, Douglas C., Gregg, Edward W., Stone, Katie, Thompson, Theodore J.
Cardiovascular diseases, Exercise, Aged women, Elderly women, Death of

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Cost-effectiveness of bone densitometry followed by treatment of osteoporosis in older men

Article Abstract:

The benefits of phosphonate therapy in older men relevant to prevention of fractures associated with osteoporosis are presented.

author: Kane, Robert L., Cummings, Steven R., Ensrud, Kristine E., Bauer, Douglas C., Melton, L. Joseph, III, Orwoll, Eric S., Taylor, Brent C., Fink, Howard A., Schousboe, John T.
United States, Care and treatment, Evaluation, Diagnosis, Medical care, Cost of, Health care costs, Osteoporosis, Bone densitometry

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subjects list: Health aspects, Prevention, Fractures (Injuries), Fractures
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