Comparison of the Atkins, Zone, Ornish, and LEARN diets for change in weight and related risk factors among overweight premenopausal women: The A to Z Weight Loss Study: A randomized trial

Article Abstract:

An A to Z Weight Loss Study was conducted to examine the effects of four weight-loss diets, that is, Atkins, Zone, LEARN and Ornish, and gradations of carbohydrate intake on weight loss and related metabolic variables in overweight and obese premenopausal women. Results of the randomized trial revealed that the Atkins diet with the lowest carbohydrate content was most effective, indicating that a low-carbohydrate, high-protein, high-fat diet might be considered effective for weight loss.

author: King, Abby C., Stafford, Randall S., Kraemer, Helena C., Gardner, Christopher D., Kiazand, Alexandre, Alhassan, Sofiya, Soowon Kim, Balise, Raymond R.
Health aspects, Women, Food and nutrition, Comparative analysis

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Efficacy and safety of low-carbohydrate diets: a systematic review

Article Abstract:

There is little evidence that low-carbohydrate diets are effective in producing long-term weight loss, according to researchers who analyzed 107 studies involving 3,268 people. Only five of the studies followed the participants for longer than three months. The weight loss that occurs from this diet occurs primarily from the reduced calories rather than the low-carbohydrate content of the diet. The Atkins diet is a well-known example of a low-carbohydrate diet.

author: Krumholz, Harlan M., Olkin, Ingram, Sanders, Lisa, Bravata, Dena M., Huang, Jane, Gardner, Christopher D., Bravata, Dawn M.
Evaluation, Low-carbohydrate diet, Low carbohydrate diet

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Nonvalidation of reported genetic risk factors for acute coronary syndrome in a large-scale replication study

Article Abstract:

A systematic literature review was performed to identify 85 variants in 70 genes and determine extensive validation of putative genetic risk factors for acute coronary syndromes (ACS). None of the 85 genetic variants implicated as susceptibility factors for ACS, which called for robust replication of putative genetic risk factors before their introduction into clinical care.

author: Krumholz, Harlan M., Lifton, Richard P., Spertus, John A., Morgan, Thomas M.
Science & research, Research, Genetic aspects, Heart diseases, Atherosclerosis, Genetic susceptibility

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subjects list: United States, Reducing diets, Atkins diet, Clinical report