Effects of physiologic pacing versus ventricular pacing on the risk of stroke and death due to cardiovascular causes

Article Abstract:

A pacemaker that stimulates both the upper and lower part of the heart does not significantly reduce the risk of stroke or death from cardiovascular disease. These so-called physiologic pacemakers mimic the heart better than pacemakers that only stimulate the ventricles, which are the lower part of the heart. But in a study of 2,568 patients who were randomly assigned to receive a ventricular or a physiologic pacemaker, the rate of stroke or death from cardiovascular disease was similar in both groups. The only benefit was a slightly lower risk of atrial fibrillation in the patients who received a physiologic pacemaker.

author: Talajic, Mario, Connolly, Stuart J., Kerr, Charles R., Gent, Michael, Roberts, Robin S., Yusuf, Salim, Gillis, Anne M., Sami, Magdi H., Tang, Anthony S.L., Klein, George J., Lau, Ching, Newman, David M.
Methods, Cardiovascular diseases, Patient outcomes, Mortality, Stroke (Disease), Stroke, Cardiac pacing

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Pacemaker therapy for prevention of syncope in patients with recurrent severe vasovagal syncope: a randomized trial

Article Abstract:

A pacemaker will not necessarily prevent vasovagal syncope, according to a study of 100 patients. Syncope is the medical term for fainting, and vasovagal syncope means the fainting is caused by a nerve disorder. In this study, all 100 patients received a pacemaker, but 48 had a real pacemaker and 52 had a dummy pacemaker. The risk of recurring fainting was similar in both groups.

author: Connolly, Stuart J., Gent, Michael, Roberts, Robin S., Sheldon, Robert, Thorpe, Kevin E., Ellenbogen, Kenneth A., Wilkoff, Bruce L., Morillo, Carlos
Electromedical and Electrotherapeutic Apparatus Manufacturing, Electromedical equipment, Pacemakers, Fainting

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Comparison of beta-Blockers, amiodarone plus beta-Blockers, or sotalol for prevention of shocks from implantable cardioverter defibrillators: The OPTIC Study: A randomized trial

Article Abstract:

A study was conducted to determine whether amiodarone plus beta-blocker or sotalol are better than beta-blocker alone for prevention of implantable cardioverter defibrillator (ICD) high-voltage shocks, which are painful. The conclusion revealed that amiodarone plus beta-blocker is effective for preventing the shocks and is more effective than sotalol but has an increased risk of drug-related adverse effects.

author: Talajic, Mario, Dorian, Paul, Connolly, Stuart J., Gent, Michael, Roberts, Robin S., Thorpe, Kevin, Bailin, Steven, Fain, Eric S., Champagne, Jean, Coutu, Benoit, Gronefeld, Gerian C., Honhnloser, Stefan H.
United States, Health aspects, Usage, Amiodarone, Electric shock, Electric shock injuries, Sotalol

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subjects list: Evaluation, Prevention, Pacemaker, Artificial (Heart), Pacemakers
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