Assocation of ABO incompatibility with elevation of nucleated red blood cell counts in term neonates

Article Abstract:

An increased amount of nucleated red blood cells in the cord blood of newborn babies could be a sign of ABO incompatibility, according to a study of 1,661 newborn babies. Nucleated blood cells are immature blood cells. Fortunately, ABO incompatibility is not usually a serious condition in most babies.

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Nucleated red blood cells in cord blood of singleton term neonates

Article Abstract:

Establishing the normal numbers of circulating red blood cells with nuclei in the newborn may prove useful in determining whether the baby experienced lack of oxygen in labor. Mature red blood cells do not have nuclei. Immature red blood cells may be rushed into circulation in response to stress. Researchers counted the number of nucleated red blood cells per 100 white cells in blood samples taken from the umbilical cords of 1,100 newborns. The values ranged from none to 89 with an average of 9 per 100 white blood cells.

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Nucleated red blood cells as a marker of acidemia in term neonates

Article Abstract:

Elevated blood levels of nucleated red blood cells in the fetus appear to be a marker of low oxygen levels during pregnancy. In a study of 1,561 newborn babies, those with elevated levels of nucleated red blood cells were more likely to have acidemia. Acidemia can be a consequence of low oxygen levels.

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