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Strategies for the treatment of sepsis

Article Abstract:

Much more research into the nature of sepsis is needed before adequate treatments can be developed. Sepsis occurs when a bacterial infection spreads into the bloodstream, causing a widespread inflammatory response. It is thought to involve endotoxins released by bacteria and some drugs have been designed to block endotoxins. Most have not been effective. The other aspect of sepsis is the inflammatory response, which could be blocked at some point. However, so far no drugs have proved effective in blocking this reaction.

Drug therapy, Inflammation, Inflammation mediators, Septic shock

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Statins and the acute-phase response

Article Abstract:

Cholesterol-lowering drugs called statins appear to reduce inflammation as well as lowering cholesterol levels. This was demonstrated in patients with increased levels of C-reactive protein, which is a marker of inflammation.

Physiological aspects, C-reactive protein, Anticholesteremic agents

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