ALS: Life and death in a bad neighborhood

Article Abstract:

Activation of microglia, the resident immune effector cells in the central nervous system (CNS), occurs as a prominent feature early in CNS inflammation, and is a consistent finding the common late-onset neuro-degenerative disorders. Findings from mouse and rat models of amyotrophic lateral sclerosis, add weightage to arguments that targeting of inflammatory cells might be a fruitful therapeutic approach.

Author: Monk, Peter N., Shaw, Pamela
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2006
Care and treatment, Risk factors, Amyotrophic lateral sclerosis

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Seeing death in the living

Article Abstract:

The authors discuss the studies on cardiomyocyte apoptosis which occurs during reperfusion injury. The topics of interest include apoptosis imaging non-ivasively in the intact heart.

Author: Gotlieb, Roberta A., Kitsis, Richard N.
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2001
Genetic aspects, Heart cells

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IL-1alpha responds to necrotic cell death

Article Abstract:

The article takes a look at acute neutrophilic response in cell death due to necrosis.

Author: Elkon, Keith B.
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2007
Science & research, Research, Cell research, Cytological research, Interleukin-1, Necrosis

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Subjects list: Health aspects, United States, Cell death
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