A prospective study of benign breast disease and the risk of breast cancer

Article Abstract:

Women with benign breast disease may have a higher risk of developing breast cancer than women who do not. Their risk may be even higher if their breast disease consists of atypical hyperplasia and they are premenopausal. A review of breast biopsy samples from 121 women in the Nurses' Health Study who subsequently developed breast cancer showed that women who had benign breast disease without atypical hyperplasia were slightly more likely to develop breast cancer, but women with atypical hyperplasia were almost four times more likely to develop breast cancer. Among women younger than 55 who had atypical hyperplasia, the risk of developing breast cancer was six times the risk in women of the same age who did not have benign breast disease. In postmenopausal women with atypical hyperplasia, the risk of developing breast cancer was twice that in women without benign breast disease.

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Radial scars in benign breast-biopsy specimens and the risk of breast cancer

Article Abstract:

Radial scars increase the risk of breast cancer independently of any other abnormality of breast tissue. Radial scars are benign abnormalities in the breast. Researchers reviewed breast biopsy samples from 1,396 women in the Nurses' Health Study, 255 of whom subsequently developed breast cancer. Seven percent of the women had one or more radial scars and most were small. Women with radial scars had twice the risk of breast cancer. Women with other abnormalities and radial scars had a higher risk of breast cancer than women with the same abnormality but no radial scars.

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Physical activity and survival after breast cancer diagnosis

Article Abstract:

A study is conducted to determine whether physical activity among women with breast cancer decreases their risk of death from breast cancer compared with more sedentary women. Physical activity after a breast cancer diagnosis might reduce the risk of death from this disease.

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