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Dietary fatty acids temporarily alter liver very long-chain fatty acid composition in mice

Article Abstract:

Mice were fed different diets of safflower, peanut, olive and glycerol trioleate oils to determine the effects of dietary fatty acids very long-chain fatty acid (VLFA) composition in tissues. Results show an increase in the liver saturated VLFA after eight months of dietary fat feeding. In addition, the levels of liver peroxisomal beta-oxidation of lignocerate were found to be similar in all groups. These findings suggest that the saturated VLFA composition of liver is influenced by dietary fatty acids shorter than VLFA.

Demyelinating diseases, Peroxisomes, Adrenoleukodystrophy

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Reply to letter of M. Meydani and S.N. Meydani

Article Abstract:

Tocopherols act as second-line defenses against increased stress of (n-3) fatty acids and should be considered in the study of protective enzymes responsible for the generation of reactive oxygen species. Furthermore, the higher urinary and thiobarbituric acid-reactive substances observed in female rats compared to male rats was explained on the basis of the difference among sexes in the pattern of fatty acid incorporation in tissues.

Vitamin E, Oxidation-reduction reaction, Oxidation-reduction reactions

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