Visualizing worm micelle dynamics and phase transitions of a charged diblock copolymer in water

Article Abstract:

The dynamics and transitions of single cylindrical micelles and vesicles composed of a charged diblock copolymer in water using fluorescence microscopy and atomic force microscopy was described. The transition kinetics and phase diagrams indicate divalent cation is about 5-10-fold more effective than monovalent in stabilizing all nonspherical morphologies.

author: Yan Geng, Discher, Dennis E., Ahmed, Fariyal, Bhasin, Nishant
Usage, Fluorescence, Micelles, Chemical properties

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Simulation of diblock copolymer self-assembly, using a coarse-grain model

Article Abstract:

Fitting the required parameters to properties taken from all-atom molecular dynamics simulations and experimental data develops a coarse-grain model for amphiphilic diblock copolymers. The model semiquantitatively reproduces a number of experimental results that were not explicitly used in the parameterization.

author: Srinivas, Goundla, Nielsen, Steve O., Shelly, john C., Discher, Dennis E., Klein, michael L.
Chemistry, Physical and theoretical, Physical chemistry, Block copolymers, Properties

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Interactions of membrane-active peptides with thick, neutral, nonzwitterionic bilayers

Article Abstract:

Antimicrobial peptide-lipid systems is studied that led to significant advancement in membrane biophysics. The study is performed on lipid bilayers that are generally charged or zwitterionic and restricted to a thickness range of 3-5 nm.

author: Discher, Dennis E., Lal, Jyotsana, Vijayan, Kandaswamy, Janmey, Paul, Goulian, Mark
Illinois, Peptides

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subjects list: Research, Copolymers
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