A Brownian dynamics simulation of an acyl chain and a molecule confined in a phospholipid bilayer in the gel and liquid crystal phases

Article Abstract:

A Brownian dynamics simulation of a saturated 16 C atom acyl chain, in an environment that reproduces a phospholipid bilayer in the gel phase, is presented. The simulations of t-PnA, a fluoresent fatty acid widely used to probe lateral lipid domains in bilayers and membranes, reinforces the validity of the mean-field description.

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Molecular dynamics simulations of ubiquinone inside a lipid bilayer

Article Abstract:

A series of multiple nanosecond molecular dynamics simulations is carried out for a dipalmitoylphosphatidycholine lipid bilayer system in water solution, with ubiquinone (UQ) freely moving inside the bilayer. The mobility and the preferential positions of the quinone molecule are studied.

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Influence of lipid chemistry on the osmotic response of cell membranes: effect of non-bilayer forming lipids

Article Abstract:

The effect of four non-bilayer forming lipids on the stability of phosphatidylcholine (PC, a bilayer forming lipid) membranes is examined. Large unilamellar vesicles were subjected to hypo-osmotic gradients and the leakage of their contents was quantified.

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