The somatic mutation theory of cancer: Growing problems with the paradigm?

Article Abstract:

The somatic mutation theory is the prevailing paradigm in cancer research for the last 50 years. The cancer is derived from a single somatic cell that has accumulated multiple DNA mutations are one of its few premises which is highlighted.

Author: Soto, Ana M., Sonnenschein, Carlos
United States, Somatic cells

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What paper say: where is the somatic mutation that causes aging?

Article Abstract:

It has been proposed that somatic mutations make major contributions to aging. The results show that the key genes involved in brain function and mitochondrial function are progressively inactivated with age.

Author: Driver, Christopher
Aging, Mitochondrial DNA, Aging (Biology)

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Problems of somatic mutation and cancer

Article Abstract:

Somatic mutation plays a key role in transforming normal cancer into cancerous cells. The rise and fall of somatic mutation rates during cancer progression is discussed.

Author: Nowak, Martin A., Frank, Steven A.
Care and treatment

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Subjects list: Research, Cancer, Antibody diversity
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